Meditsinskaya Fizika最新文献_第4页

The Influence of the Technical Parameters of the SRS Plans on the Dosimetric and Radiobiologic Evaluation SRS计划技术参数对剂量学和放射生物学评价的影响

Meditsinskaya Fizika Pub Date : 2022-07-12 DOI: 10.52775/1810-200x-2022-94-2-33-41

I. R. Sagov, Y. Sutygina, E. Sukhikh

{"title":"The Influence of the Technical Parameters of the SRS Plans on the Dosimetric and Radiobiologic Evaluation","authors":"I. R. Sagov, Y. Sutygina, E. Sukhikh","doi":"10.52775/1810-200x-2022-94-2-33-41","DOIUrl":"https://doi.org/10.52775/1810-200x-2022-94-2-33-41","url":null,"abstract":"Background: The purpose of this study was to evaluate influence of technical parameters on Stereotactic Radiosurgery (SRS) plans on dosimetric evaluation. Materials and methods: There were considered and selected two patients who had brain tumors and had been treating in Tomsk Regional Oncology Center. All treatment plans were simulated using the Monaco treatment planning system v 5.11 (Elekta Instrument AB, Stockholm) on the Elekta Synergy linac with photon beam nominal energy 6 MV. For study there were created several plans with different technical parameters (number of arcs, increment, gantry angle, collimator angle, couch angle, minimum segment width). Each plan was evaluated by metrics such as Conformal, Homogeneity and Gradient indexes. Results: If we use a large increment value it may create few sectors and which can produce low quality plans, and increase treatment time, otherwise if we use a too small increment value it will give us more sectors and they can increase the quality of the plan. The dose which was measured with higher MSW showed to us better agreement with the calculated dose. Conclusion: It is valuable to carefully select technical parameters. The use of rigid increment value, segment width or increasing number of arcs can make plans have lower quality and to rise time of treatment.","PeriodicalId":222791,"journal":{"name":"Meditsinskaya Fizika","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132369016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment and Registration of Effective Doses Used in Diagnostic Nuclear Medicine Examinations 核医学诊断检查中有效剂量的评估和注册

Meditsinskaya Fizika Pub Date : 2022-07-12 DOI: 10.52775/1810-200x-2022-94-2-64-75

I. Zvonova, L. Chipiga, A. Vodovatov, E. R. Ladanova, S. Ryzhov

{"title":"Assessment and Registration of Effective Doses Used in Diagnostic Nuclear Medicine Examinations","authors":"I. Zvonova, L. Chipiga, A. Vodovatov, E. R. Ladanova, S. Ryzhov","doi":"10.52775/1810-200x-2022-94-2-64-75","DOIUrl":"https://doi.org/10.52775/1810-200x-2022-94-2-64-75","url":null,"abstract":"Over the recent period, the Russian healthcare system has been undertaking a nation-wide renewal of equipment for nuclear medicine, which, in turn, opens a gate to new diagnostic radiopharmaceuticals (DRPs) to routine practice. The market welcomed a new class of targeted DRPs. Dozens of PET centres and diagnostic rooms where DRPs with ultrashort-lived radionuclides are used for medical examination have been put into operation. All this dictates the need to modify the existing guidelines that govern this area. In 2021, there was an update in the procedural guidelines (PGs) MU 2.6.1.3700-21 “Assessment and registration of effective doses used in diagnostic nuclear medicine examinations”. The document presented the dose coefficients for new DRPs based on the latest data from the International Commission on Radiological Protection and the literature. This included calculation of the effective doses (using tissue weighting factors) from 1 MBq of radioactivity for approximately 280 DRPs used across five different age groups, as per ICRP Publication 60. These PGs apply to diagnostic nuclear medicine examinations performed using DRPs, scintigraphy, single-photon emission computed tomography (SPECT) and positron emission tomography (PET) alone or in combination with X-ray computed tomography (SPECT/CT; PET/CT). The guidelines do not apply to radionuclide therapies that involve DRP administration that require individual planning and assessment of the absorbed doses across the target regions, critical organs and other radiosensitive organs and tissues.","PeriodicalId":222791,"journal":{"name":"Meditsinskaya Fizika","volume":" 12","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132075898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantitative Assessment of the Quality of External Radiotherapy Planning for Patients with Prostate Cancer 前列腺癌患者外放疗计划质量的定量评价

Meditsinskaya Fizika Pub Date : 2022-07-12 DOI: 10.52775/1810-200x-2022-94-2-12-19

Yu. A. Lazareva, I. Lebedenko

{"title":"Quantitative Assessment of the Quality of External Radiotherapy Planning for Patients with Prostate Cancer","authors":"Yu. A. Lazareva, I. Lebedenko","doi":"10.52775/1810-200x-2022-94-2-12-19","DOIUrl":"https://doi.org/10.52775/1810-200x-2022-94-2-12-19","url":null,"abstract":"Purpose. To quantify the quality of treatment planning for patients with prostate cancer for three different radiotherapy technologies. Materials and methods. The quality of irradiation planning was assessed using the index of homogeneity, conformality and comparison of critical organs doses for 40 patients with prostate cancer using various irradiation technologies: 3D conformal radiation therapy 3DCRT, radiation therapy with intensity modulation IMRT, radiation therapy with intensity modulation in rotation mode RapidArc. The technologies are implemented on conventional electron accelerators of the Clinac iX (Varian, USA), Clinac 2300 CD (Varian, USA) and UniquePower (Varian, USA) models with a nominal photon radiation energy 6 and 18 MeV. Results. The dependences of the homogeneity indices HI, conformality CI within the target, and critical organs doses on the irradiation technology for patients with prostate cancer were obtained. Taking into account the predictive capabilities of the HI index for relapse-free survival, the optimal technology for irradiating patients was chosen. It has been shown that Rapid Arc technology dominates for prostate cancer.","PeriodicalId":222791,"journal":{"name":"Meditsinskaya Fizika","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130501851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Experience of Radiation Theapy Using Non-Coplanar Fields Angles VMAT in the Implementation of Radiotherapy for Prostata Cancer Patients 非共面视场角VMAT在前列腺癌患者放疗中的应用体会

Meditsinskaya Fizika Pub Date : 2022-07-12 DOI: 10.52775/1810-200x-2022-94-2-27-32

S. N. Buksha, Y. Y. Ionkova

引用次数: 0

Development and Application of Diagnostic Reference Levels for Adult Patients in Diagnostic Radiology 成人放射诊断参考水平的发展与应用

Meditsinskaya Fizika Pub Date : 2022-04-25 DOI: 10.52775/1810-200x-2022-93-1-81-96

Y. Druzhinina, Z. Lantukh, A. Vodovatov, S. Morozov, S. Ryzhov, E. N. Sokolov, M. Shatenok, L. Chipiga, K. Tolkachev

{"title":"Development and Application of Diagnostic Reference Levels for Adult Patients in Diagnostic Radiology","authors":"Y. Druzhinina, Z. Lantukh, A. Vodovatov, S. Morozov, S. Ryzhov, E. N. Sokolov, M. Shatenok, L. Chipiga, K. Tolkachev","doi":"10.52775/1810-200x-2022-93-1-81-96","DOIUrl":"https://doi.org/10.52775/1810-200x-2022-93-1-81-96","url":null,"abstract":"Radiation protection of patients is based on the principles of justification and optimization. The principle of optimization, the most important and effective one, relies on the system of diagnostic reference levels (DRLs) that have been successfully used in global practice and are officially introduced in Basic Sanitary Rules for Radiation Safety-99/2010. \u0000The guidelines establish diagnostic reference levels for adult X ray imaging in medical settings and determine their application to balance radiation protection of patients and the provision of high-quality diagnostic information. The guidelines relate to medical X-ray diagnostic and radiological examinations and are intended for the staff and management of medical facilities, agencies that are responsible for radiation control in medical facilities, and can also be used by expert institutions and agencies for health security and disease control. \u0000The guidelines consider and compare various methods to determine the DRLs based on measured and/or calculated dosimetric parameters, such as the dose-area product, entrance dose, mean glandular dose, activity, and effective dose. Furthermore, they propose a scheme to determine the standard dose values depending on the type of X-ray diagnostic device used; present the steps to apply the DRLs in practice; establish measures in case the standard doses exceed the DRLs; and define the levels to perform optimization.","PeriodicalId":222791,"journal":{"name":"Meditsinskaya Fizika","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128922841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancement of Genotoxic Activity of g-Irradiation of Human Lung Carcinoma A549 cells in the Presence of Gold Nanoparticles 金纳米颗粒对肺癌A549细胞基因毒性的增强作用

Meditsinskaya Fizika Pub Date : 2022-01-31 DOI: 10.52775/1810-200x-2021-92-4-24-31

А. Rzyanina, G. Mytsin, K. Voskanyan, V. Gaevskiy

引用次数: 0

Independent Dose Calculation when External Radiotherapy Cancer Patient Planning 癌症患者计划外放疗时的独立剂量计算

Meditsinskaya Fizika Pub Date : 2022-01-31 DOI: 10.52775/1810-200x-2021-92-4-32-38

I. Lebedenko, L. Kosenkova, E. O. Sannicova, O. S. Zaichenko

{"title":"Independent Dose Calculation when External Radiotherapy Cancer Patient Planning","authors":"I. Lebedenko, L. Kosenkova, E. O. Sannicova, O. S. Zaichenko","doi":"10.52775/1810-200x-2021-92-4-32-38","DOIUrl":"https://doi.org/10.52775/1810-200x-2021-92-4-32-38","url":null,"abstract":"Purpose: Independent dose calculation (IDC) and quantitative processing of the calculating the 3D \u0000CRT, IMRT, RapidArc results of patients irradiation plans was conducted. Criteria for passing the exposure plans for the implementation of radiation therapy was developed. \u0000Materials and methods: An independent manual dose calculation of patient exposure plans was performed using 3D CRT, IMRT and RapidArc techniques. Discrepancies were obtained for three groups of \u0000patients: 3D CRT group contained 1584 patients, the group of patients who received IMRT included \u0000647 patients. The patient group, in which rotary mode RapidArc was performed, included 364 patients. \u0000Results: As the analysis result of the IDC for 3D CRT, IMRT, RapidArc technologies, the quantitative indicators were ranked. The allowable discrepancies between the dose IDC and the dose calculated by the \u0000TPS were proposed for consideration: for 3D CRT technology from –5 to +10 %, for IMRT from 1.5 to 6 \u0000times, for RapidArc from 1, 5 to 2.5 times. Outside the specified intervals, it is necessary to check and \u0000reschedule plans or conduct verification.","PeriodicalId":222791,"journal":{"name":"Meditsinskaya Fizika","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114082105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Features of Distributions Created in a Water Phantom by Narrow Bremsstrahlung Radiation Beams from 10 to 20 MV 10 ~ 20 MV窄轫致辐射光束在水影中产生的分布特征

Meditsinskaya Fizika Pub Date : 2022-01-31 DOI: 10.52775/1810-200x-2021-92-4-13-23

V. Klimanov, A. Belousov, Y. Kirpichev, M. Kolyvanova, J. Z. Smirnova

{"title":"Features of Distributions Created in a Water Phantom by Narrow Bremsstrahlung Radiation Beams from 10 to 20 MV","authors":"V. Klimanov, A. Belousov, Y. Kirpichev, M. Kolyvanova, J. Z. Smirnova","doi":"10.52775/1810-200x-2021-92-4-13-23","DOIUrl":"https://doi.org/10.52775/1810-200x-2021-92-4-13-23","url":null,"abstract":"The paper analyzes the features of the spatial and energy distributions of photons in depth, in radius \u0000and in energy for small fields created in water by narrow beams of high-energy bremsstrahlung radiation from medical accelerators and mono-directional, monoenergetic beams of photons. In particular, \u0000the relationship between the spatial dependences of the absorbed dose, total kerma, and ionization \u0000kerma is discussed. Using numerical simulation, the features of photon spectra in small fields at a \u0000depth of 10 cm in a water phantom for bremsstrahlung beams with maximum energies of 10, 15, 18 \u0000and 20 MeV were determined as applied to the design of Varian accelerator heads. It is shown that, in \u0000contrast to wide fields, the energy distribution of photons in these fields practically does not change \u0000within the central region of the field and strongly softens when leaving this region. With a decrease in \u0000the size of small fields from 4.04.0 to 0.50.5 cm, a certain hardening of the spectra is observed in the \u0000central region (the average energy increases by 2–4 %) and is much more significant outside this region. \u0000The work also determined the values of the clinical dimensions of small fields generated by high-energy \u0000beams of Varian accelerators of different energies in a water phantom at a depth of 10 cm, depending on \u0000the settings of the collimation system. \u0000This work was carried out with the financial support of the Russian Foundation for Basic Research and \u0000SITMA within the framework of scientific project No. 18-52-34008.","PeriodicalId":222791,"journal":{"name":"Meditsinskaya Fizika","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122906982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perspectives of Technical Equipment Development for External Radiotherapy in Russian Federation in My View 我认为俄罗斯联邦外放射治疗技术设备发展的展望

Meditsinskaya Fizika Pub Date : 2022-01-31 DOI: 10.52775/1810-200x-2021-92-4-5-12

I. Tarutin

{"title":"Perspectives of Technical Equipment Development for External Radiotherapy in Russian Federation in My View","authors":"I. Tarutin","doi":"10.52775/1810-200x-2021-92-4-5-12","DOIUrl":"https://doi.org/10.52775/1810-200x-2021-92-4-5-12","url":null,"abstract":"This article is devoted to problems of radiotherapy technical maintenance development in Russian Federation on next 10–15 years. The next trends of development are discussed: \u00001. The composition of equipment included in radiotherapy complexes. \u00002. The situation with development of high technology radiotherapy (HTR) on Russia in 2021 year. \u00003. The international modes to number of HTR complexes included linear accelerators (LA). \u00004. The necessity in future number of LA and HTR complexes in Russia. \u00005. how calculate the number of LA and HTR complexes in every separate clinic. \u00006. Special possibilities of main Russian clinics. \u00007. Where to purchase HTR complexes included LA to other small clinics? \u00008. What types of LA is necessary to buy? \u00009. What types of LA is necessary produce on Russian plants? \u000010.What cost of project will be if it will be accept? \u000011.The development of service centers. \u000012.The staff maintenance. \u000013.The creation of building for disposed new technique or reconstruction of old treatment rooms. \u000014.The normative rules limit. \u000015.New types of LA. \u000016.Metrology maintenance. \u000017.Dosimetrical maintenance. \u000018.the development of proton accelerators and neutron generators in Russia. \u000019.How many years is necessary to wait of production Russian LA beginning? \u0000The problem the creation of technical equipment maintenance in Russia for modern radiotherapy on \u0000leading international level is very complex, heterogeneous and expensive. It can’t be realized without \u0000serious state support. But it is necessary to begin this realization even now. The specialists of necessary \u0000level are enough in country. It is necessary to create the general conceptual project of it realization, and \u0000after that create separate but very large problems included in it.","PeriodicalId":222791,"journal":{"name":"Meditsinskaya Fizika","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129027660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis o the State of The Problem of Radioactive Waste in Nuclear Medicine 核医学中放射性废物问题现状分析

Meditsinskaya Fizika Pub Date : 2022-01-31 DOI: 10.52775/1810-200x-2021-92-4-45-54

B. Narkevich

引用次数: 0