Meditsinskaya Fizika最新文献

{"title":"Experience in the Treatment of Breast Cancer Using Tunnel Type Linear Accelerator","authors":"A. S. Uvarov, E. V. Shindiakin, V. K. Platonov, M. Zemko, L. Galchenko","doi":"10.52775/1810-200x-2022-96-4-37-42","DOIUrl":"https://doi.org/10.52775/1810-200x-2022-96-4-37-42","url":null,"abstract":"Purpose: Describes the features of dosimetric planning for breast cancer and conducts statistics analysis of the radiation treatment planning results, while taking into account 2.5 years of work experience on the Halcyon linear accelerator at the Irkutsk Regional Cancer Center. \u0000Materials and methods: Varian Halcyon tunnel type linear accelerator and Varian TrueBeam C-arm linear accelerator were used for breast irradiation. Treatment planning was performed in the Eclipse planning system, Acuros dose calculation algorithm. The experience of using the specified equipment and developments in the field of radiation treatment planning using the Halcyon system are presented. \u0000Results: Developed an approach to planning breast radiation at the Halcyon linear accelerator. A retrospective analysis of 84 radiation treatment plans on linear accelerators of various types was carried out. Breast treatment plans for Halcyon linear accelerator have equal dosimetric parameters in comparison to the TrueBeam treatment plans. \u0000Conclusion: Linear accelerator Halcyon can be used for treating breast cancer if staff understands specifics of treatment planning and treatment delivery.","PeriodicalId":222791,"journal":{"name":"Meditsinskaya Fizika","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127589936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the Constancy of the Dosimetric Parameters of the Proton Therapy System","authors":"V. Kiselev, A. Demidova, Y. Udalov, A. N. Kolesnikov, S. E. Gritsenko, E. N. Ustimova","doi":"10.52775/1810-200x-2022-95-3-65-70","DOIUrl":"https://doi.org/10.52775/1810-200x-2022-95-3-65-70","url":null,"abstract":"Purpose: Determination of fluctuation ranges of dosimetry parameters of the proton therapy system \u0000(PTS) to clarify the permissible limit deviations. \u0000Methods and materials: The basis for the quality assurance program (QA) of the PTS is the report of the \u0000American Association of Physicists in Medicine AAPM TG-224. According to this report, the QA program is a living, adaptive document that needs to be refined, corrected and optimized taking into account the features of the PTS being in use and the available dosimetry equipment. After setting-up \u0000checks within the framework of the daily QA program, it became possible to automatically collect data \u0000containing dosimetry parameters of the PTS for subsequent analysis. It was decided to investigate the \u0000stability over time of some dosimetry parameters of the PTS in order to determine the ranges of their \u0000fluctuations and, as a result, to clarify the permissible deviations of these parameters. \u0000Results: The stability of the parameters associated with the constancy of the proton beam energy selection was studied. As a result, the study showed that the values of the parameters associated with the \u0000constancy of the proton beam energy selection fluctuated within much smaller limits compared to \u0000those proposed in TG-224. \u0000Conclusion: The obtained result may allow us to reconsider the approach to proton therapy planning \u0000system in the FSBI FSCCRO of the FMBA of Russia, in particular, to the choice of PTV margins. The new \u0000refined tolerances for the maximum deviations of the analyzed parameters are proposed in this research work","PeriodicalId":222791,"journal":{"name":"Meditsinskaya Fizika","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117350681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glossary of Terms and Concepts in Medical Padiation Physics. Terminology Used in Technological Support of Radiation Therapy","authors":"S. Vatnitsky","doi":"10.52775/1810-200x-2022-95-3-86-105","DOIUrl":"https://doi.org/10.52775/1810-200x-2022-95-3-86-105","url":null,"abstract":"Medical radiation physics supports medical diagnostic and treatment process based on the use of ionizing radiation in radiation therapy, nuclear medicine, radiation diagnostics and radiation safety of patients and personnel. However, the successful implementation of this process requires close interaction \u0000of specialists in all the above areas. The basis of such interaction is the unification of the terminology \u0000and concepts used at various stages of the diagnostic and treatment process. The article presents a \u0000glossary on technological support of radiation therapy which contains the most commonly used terms \u0000in this field and explanations for each of them. The glossary is intended for use both in professional education, including postgraduate education, and for medical physicists and radiation oncologists working in radiological medical organization","PeriodicalId":222791,"journal":{"name":"Meditsinskaya Fizika","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124827076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methodical Notes on the Term “Intensity” in Medicine and Physics","authors":"D. A. Rogatkin","doi":"10.52775/1810-200x-2022-95-3-106-113","DOIUrl":"https://doi.org/10.52775/1810-200x-2022-95-3-106-113","url":null,"abstract":"In the article, as a discussion of the publication [1] published earlier in the journal on terminology in \u0000medical physics, the application of the term intensity in medicine and physics is considered. It is \u0000shown, contrary to the statement of the original article, that the term intensity is very widely used in \u0000various branches of physics, from optics and photometry to electrodynamics and radiophysics. At the \u0000same time, its ambiguity and non-identity of the use in different branches of physics, including the different dimensions of these quantities used, which often introduces a confusion and leads to errors in \u0000results, is also shown and discussed. For optics and photometry, according to the recommendations of \u0000the international SI system, the term intensity should be unambiguously understood as a quantity \u0000with the dimension W·sr–1. This is the main physical quantity of the SI system that characterizes radiation, but in Russian-language publications it is also called as a force of radiation, which can be misleading.","PeriodicalId":222791,"journal":{"name":"Meditsinskaya Fizika","volume":"171 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125937567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"On the Relationship Between Spatial and Temporary Dose Distribution in Radiotherapy Optimization","authors":"V. F. Lisin","doi":"10.52775/1810-200x-2022-94-2-20-26","DOIUrl":"https://doi.org/10.52775/1810-200x-2022-94-2-20-26","url":null,"abstract":"The method of mathematical modeling was used to conduct studies aimed at establishing the dependence of optimal dose-fractionation regimens on the spatial dose distribution in tissue and on the tumor location with respect to the spatial dose distribution. The TDF model was used to describe the response of normal tissue to radiation, and the multi-target model was used to describe the reaction of the tumor to radiation. It was shown for the first time that a change in the tumor location relative to the existing spatial dose distribution, as well as a change in the nature of its spatial distribution, led to a change in the parameters of the optimal dose fractionation regimen.","PeriodicalId":222791,"journal":{"name":"Meditsinskaya Fizika","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114797013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Studying IR Photohyperthermia Sensitized by Titanium Nitride Nanoparticles Using Tissue-Equivalent Phantoms","authors":"P. Shakhov, G. Tikhonowski, E. Popova-Kuznetsova, A. Zakharkiv, E. Gromushkina, S. M. Klimentov, A. Popov","doi":"10.52775/1810-200x-2022-94-2-85-95","DOIUrl":"https://doi.org/10.52775/1810-200x-2022-94-2-85-95","url":null,"abstract":"Purpose: To use tissue-equivalent phantom for studies of thermal fields in biological tissues during IR photo hyperthermia with plasmonic titanium nitride nanoparticles (TiN NPs). Material and methods: Gel phantom based on polyacrylamide (PAA) with addition of naphtol green dye and intralipid 10% was created. Optical properties (reduced scattering coefficient) of phantom ingredients were determined using added absorber technique. Thermal field distribution was studied with IR thermal imaging technique. 50 nm plasmonic TiN NPs, synthetized by laser ablation in liquids, were used as sensitizers of photothermic action. Photothermal experiments were performed using two phantoms: a phantom with homogeneous optical parameters, which are relevant to biological tissues (absorption coefficient µa=0.35 сm-1, reduced scattering coefficient µ's=30 сm-1), and a phantom containing 0.02 mg/ml of TiN NPs, which increased absorption coefficient by Dµa=0.65 сm-1. The part of phantom with the NPs was located under 5 mm layer of NPs-free phantom. Photothermal effect was excited by CW laser irradiation of 830 nm wavelength and 16 W/cm2 intensity (900 mW, beam diameter: 1.3 mm) for 2 min. Thermal field distribution inside the phantom was measured by IR thermal camera. Results: A tissue-equivalent gel phantom with independently tunable absorption and scattering coefficients was designed. The phantom had cubic shape with 30 30 30 mm size. Results of photothermal experiments showed that the use of TiN NPs as sensitizers IR photohyperthermia leads to a significant increase in tissue temperature (up to 5 degrees Celsius) at distances up to 15 mm under the phantom surface. In addition, a simple experimental setup for measuring scattering coefficient of a liquid phantom ingredients was described. Conclusion: A simple method for preparation of PAA phantom for modelling photothermal heating of biological tissues and studying thermal fields distributions was described. The phantom is handy and allows one to quickly experimentally simulate the photothermal response of biological tissues, including tissues containing various spatial distributions of photosensitive NPs. TiN NPs experimentally confirmed to be an effective sensitizer of IR photothermal effect.","PeriodicalId":222791,"journal":{"name":"Meditsinskaya Fizika","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133768312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glossary of Terms and Concepts in Medical Padiation Physics - Terminology in Proton and Light Ion Beam Radiation Therapy","authors":"S. Vatnitsky","doi":"10.52775/1810-200x-2022-94-2-96-107","DOIUrl":"https://doi.org/10.52775/1810-200x-2022-94-2-96-107","url":null,"abstract":"Medical radiation physics supports medical diagnostic and treatment process based on the use of ionizing radiation in radiation therapy, nuclear medicine, radiation diagnostics and radiation safety of patients and personnel. However, the successful implementation of this process requires close interaction of specialists in all the above areas. The basis of such interaction is the unification of the terminology and concepts used at various stages of the diagnostic and treatment process. This development is very important for high technological applications such as proton and light ion beam radiation therapy, where the description and correct and unambiguous interpretation of the terminology in the Russianlanguage literature is practically absent. The article presents a glossary on proton and light ion beam radiation therapy which contains the most commonly used terms in this field and explanations for each of them. The glossary is intended for use both in professional education, including postgraduate education, and for medical physicists and radiation oncologists working in radiological medical organizations.","PeriodicalId":222791,"journal":{"name":"Meditsinskaya Fizika","volume":"259 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132861709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of CTV to PTV Margin for Head and Neck Cancer with Daily Setup Using MVCBCT Imaging","authors":"K. S. Bessarabova, A. V. Mikhailova, I. Lebedenko, T. Krylova","doi":"10.52775/1810-200x-2022-94-2-5-11","DOIUrl":"https://doi.org/10.52775/1810-200x-2022-94-2-5-11","url":null,"abstract":"Purpose: Geometrical inaccuracies of setup using MV-CBCT imaging for patients with head and neck cancer were evaluated. Possibility of modifying of CTV to PTV margin while delineation of such tumors was estimated. Materials and methods: Additional adjustment of simulation kV CT pictures with MV-CBCT images received during the implementation of the online protocol was conducted for 35 patients with head and neck cancer. Offline analysis revealed the discrepancy in the results of online correction and offline analyses. CTV to PTV margin considering daily setup was computed. Results: Obtained values of CTV to PTV margin: 2.4 mm in Vrt, 2.1 mm in Lng and 2.5 mm in Lat. Upward variations from 5 mm margin used in unit were registered for 2 patients. Conclusions: Reduction of CTV to PTV margin up to 2.5 mm is precarious because CTV dose coverage is not reasonable for all patients. Implementation of routine work practice in Off-line Review is required for identification of problem cases and determination of individual CTV to PTV margin.","PeriodicalId":222791,"journal":{"name":"Meditsinskaya Fizika","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134348522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spherical Collimation Systems Radiation Fields Monte Carlo Calculation","authors":"D. D. Granin, O. V. Pashkov, P. Medvedev","doi":"10.52775/1810-200x-2022-94-2-46-63","DOIUrl":"https://doi.org/10.52775/1810-200x-2022-94-2-46-63","url":null,"abstract":"Purpose: To determine the optimal parameters of the collimation system of the gamma therapeutic apparatus. Material and methods: collimation system parameters Monte Carlo simulation in Geant4 Software Package. Results: Simulation in the Geant4 software package is a reliable tool for solving such problems The good agreement between calculated and experimental data was achieved. The proposed system of spherical beam collimation using a source similar to GIK-9-3(4) (manufactured by Mayak), with a value of SSD=1000 mm, is capable of providing the required characteristics of the radiation field over the entire range of its sizes. It seems appropriate to consider the reduction of radiation leakage with the help of a jagged shape of the contacting surfaces of the collimator jaws, since the dose is mainly due to leakage through poorly connected collimator jaws, reduced to a negative angle. Conclusion: The performed calculation of the collimation system makes it possible to use the obtained results for the design of radiation heads of gamma therapeutic devices without additional scientific research. The paper also provides a detailed description of the libraries of physical processes used in Geant4, which allows the reader, if necessary, to repeat the experiment for his/her own needs.","PeriodicalId":222791,"journal":{"name":"Meditsinskaya Fizika","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129193596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Possibilities of Using DWIBS for Clinical Tasks with the Measurement of the Apparent Diffusion Coefficient","authors":"V. O. Ripp, P. Menshchikov, D. Kupriyanov, P. Bulanov, K. Sergunova, D. Semenov, T. P. Berezovskaya, S. A. Ivanov, A. Kaprin","doi":"10.52775/1810-200x-2022-94-2-76-84","DOIUrl":"https://doi.org/10.52775/1810-200x-2022-94-2-76-84","url":null,"abstract":"Additional suppression of the background signal in diffusion-weighted images (DWIBS) allows to get more contrast images to highlight areas with restricted diffusion, for example, in many malignant primary and metastatic tumors. Due to fundamental differences in DWIBS and DWI acquisition, the apparent diffusion coefficient (ADC) values may differ, which could negatively affect attempts to compare with the available literature data or with conventional DWI studies. Purpose. Evaluation of the correctness of the calculation of the ADC values based on DWIBS images, compared to regular DWI. Material and methods. A comparative analysis of the ADC values obtained using DWIBS and conventional DWI on an MR-compatible phantom and on 20 healthy volunteers was carried out. Free breathing DWIBS as well as DWI with breath synchronization were acquired using 1.5 T MRI scanner. Results and discussion. ADC values measured with DWIBS and DWI were found to coincides well both for the phantom and for the volunteers in all the areas (vertebra, kidney, spleen), except for the liver, where the ADC values obtained from DWIBS images were 11 % lower than with standard DWI (1.06 vs 0.92 mm2/s). This may be due to the greater displacement of the liver during respiratory movements. The advantages of the DWIBS technique include a significant decrease in scan time (1.5-2 times with a 10 % decrease in signal-to-noise ratio compared to routine DWI), which allows for a quantitative analysis of ADC values in a whole-body scan in a comfortable timing for the patient. Conclusion. DWIBS can be recommended for calculating ADC values, however, a comparative analysis of ADC values in organs and tissues exposed to strong respiratory movements require additional assessments of repeatability and reproducibility directly when comparing areas with a strongly pronounced diffusion restriction.","PeriodicalId":222791,"journal":{"name":"Meditsinskaya Fizika","volume":"115 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131447569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}