{"title":"Seven-day buprenorphine feasible in patients with minimal to mild opioid withdrawal","authors":"","doi":"10.1002/pu.31226","DOIUrl":"https://doi.org/10.1002/pu.31226","url":null,"abstract":"<p>Patients with opioid use disorder (OUD) who exhibited minimal to mild withdrawal at baseline experienced positive outcomes with use of an injectable 7-day formulation of buprenorphine, a nonrandomized trial has found. The study sample of 100 adults reported few serious adverse events and a high degree of satisfaction with the extended-release formulation of buprenorphine.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"35 11","pages":"3"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142404278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antidepressants and changes in adiposity","authors":"Y. W. Francis Lam Pharm.D., FCCP","doi":"10.1002/pu.31225","DOIUrl":"https://doi.org/10.1002/pu.31225","url":null,"abstract":"<p>It is not uncommon for patients with depression to have obesity as a comorbid condition (Mulugeta et al., 2019). Although antidepressants have been implicated in weight gain in patients with depression, the research evidence is conflicting and little data exist for assessing weight changes after more than 12 months of antidepressant therapy.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"35 11","pages":"2"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142404341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The vexing problem of akathisia","authors":"Lawrence H. Price M.D.","doi":"10.1002/pu.31228","DOIUrl":"https://doi.org/10.1002/pu.31228","url":null,"abstract":"<p>Sometimes, in the course of perusing the literature for articles that I think warrant coverage in the <i>Update</i>, I come across a worthy study that evokes a sense of déjà vu. When I investigate further, I usually find out that what I'm being reminded of is a study on the same topic from years earlier. Occasionally, it's actually the same study, and I've forgotten that we've already covered it in a previous issue (in the worst of these cases, I don't catch my error — fortunately, nothing gets by our ace managing editor, Gary Enos). Rarely, it's similar to a different study I've seen recently, but one that we didn't cover.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"35 11","pages":"7"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142404150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Suvorexant, lemborexant effective for preventing delirium in hospital patients","authors":"","doi":"10.1002/pu.31233","DOIUrl":"https://doi.org/10.1002/pu.31233","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"35 11","pages":"8"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142404154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis identifies factors associated with response to ketamine for TRD","authors":"","doi":"10.1002/pu.31210","DOIUrl":"https://doi.org/10.1002/pu.31210","url":null,"abstract":"<p>Outpatient treatment initiators and individuals with moderately severe or severe pretreatment depression were most likely to benefit from ketamine treatment over electroconvulsive therapy (ECT) for treatment-resistant depression (TRD), a newly published analysis has found. Individuals with the most severe pretreatment depression saw greater benefit from ECT early in treatment. Study results were published online June 25, 2024, in <i>JAMA Network Open</i>.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"35 10","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142137648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antipsychotic-associated breast cancer","authors":"Y. W. Francis Lam Pharm.D., FCCP","doi":"10.1002/pu.31212","DOIUrl":"https://doi.org/10.1002/pu.31212","url":null,"abstract":"<p>Research data suggest an association between antipsychotic-induced hyperprolactinemia and higher risk of breast cancer (Rahman et al., 2022; also, see “Breast cancer risk with antipsychotic use linked to prolactin levels;” https://doi.org/10.1002/pu.30853). This is likely secondary to the anti-dopaminergic properties of antipsychotics, especially those of first-generation agents.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"35 10","pages":"2"},"PeriodicalIF":0.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142137650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antidepressants for bipolar depression do not increase risk of mania","authors":"","doi":"10.1002/pu.31220","DOIUrl":"https://doi.org/10.1002/pu.31220","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"35 10","pages":"8"},"PeriodicalIF":0.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142137710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Benzodiazepine use not associated with increased risk of dementia","authors":"","doi":"10.1002/pu.31217","DOIUrl":"https://doi.org/10.1002/pu.31217","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"35 10","pages":"7"},"PeriodicalIF":0.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142137777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oral formulation of ketamine effective for treatment-resistant depression","authors":"","doi":"10.1002/pu.31215","DOIUrl":"https://doi.org/10.1002/pu.31215","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"35 10","pages":"6-7"},"PeriodicalIF":0.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142137708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}