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The Brown University Psychopharmacology Update最新文献

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Your Medication Information 您的用药信息
The Brown University Psychopharmacology Update Pub Date : 2025-04-29 DOI: 10.1002/pu.31319
{"title":"Your Medication Information","authors":"","doi":"10.1002/pu.31319","DOIUrl":"https://doi.org/10.1002/pu.31319","url":null,"abstract":"<p>Paliperidone (generic) – Invega (brand)</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 6","pages":"9-10"},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143884097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study suggests benefit of continuing antipsychotic during pregnancy 研究表明怀孕期间持续服用抗精神病药物有益
The Brown University Psychopharmacology Update Pub Date : 2025-03-27 DOI: 10.1002/pu.31303
{"title":"Study suggests benefit of continuing antipsychotic during pregnancy","authors":"","doi":"10.1002/pu.31303","DOIUrl":"https://doi.org/10.1002/pu.31303","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 5","pages":"6-8"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intravenous hydroxyzine shows promise for treatment of delirium 静脉注射羟嗪有望治疗谵妄
The Brown University Psychopharmacology Update Pub Date : 2025-03-27 DOI: 10.1002/pu.31305
{"title":"Intravenous hydroxyzine shows promise for treatment of delirium","authors":"","doi":"10.1002/pu.31305","DOIUrl":"https://doi.org/10.1002/pu.31305","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 5","pages":"8"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study finds low correspondence between known genetic variations and treatment targets 研究发现，已知基因变异与治疗目标之间的相关性较低
The Brown University Psychopharmacology Update Pub Date : 2025-03-27 DOI: 10.1002/pu.31304
{"title":"Study finds low correspondence between known genetic variations and treatment targets","authors":"","doi":"10.1002/pu.31304","DOIUrl":"https://doi.org/10.1002/pu.31304","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 5","pages":"8"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psilocybin-assisted therapy leads to personality shifts in patients with alcohol use disorder 裸盖菇素辅助治疗导致酒精使用障碍患者的人格转变
The Brown University Psychopharmacology Update Pub Date : 2025-03-27 DOI: 10.1002/pu.31300
{"title":"Psilocybin-assisted therapy leads to personality shifts in patients with alcohol use disorder","authors":"","doi":"10.1002/pu.31300","DOIUrl":"https://doi.org/10.1002/pu.31300","url":null,"abstract":"<p>Adults with alcohol use disorder who received two sessions of psilocybin-assisted therapy demonstrated personality shifts toward normalization of abnormal trait expression, a secondary analysis of a randomized trial has found. A decrease in impulsiveness was found to be associated with reduced drinking post-treatment, with the strongest effect for psilocybin-treated individuals who had engaged in moderate- or high-risk drinking before treatment.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 5","pages":"3-4"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comprehensive study of GLP-1 effects suggests neuropsychiatric benefits 综合研究表明GLP-1对神经精神有益处
The Brown University Psychopharmacology Update Pub Date : 2025-03-27 DOI: 10.1002/pu.31301
{"title":"Comprehensive study of GLP-1 effects suggests neuropsychiatric benefits","authors":"","doi":"10.1002/pu.31301","DOIUrl":"https://doi.org/10.1002/pu.31301","url":null,"abstract":"<p>A study evaluating the effects of glucagon-like peptide-1 (GLP-1) receptor agonists on 175 health outcomes found an association with lower risk of substance use, psychotic, and neurocognitive disorders in patients diagnosed with diabetes. Conversely, use of GLP-1 drugs was associated with higher risk of gastrointestinal disorders.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 5","pages":"4-5"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Your Medication Information 您的用药信息
The Brown University Psychopharmacology Update Pub Date : 2025-03-27 DOI: 10.1002/pu.31306
{"title":"Your Medication Information","authors":"","doi":"10.1002/pu.31306","DOIUrl":"https://doi.org/10.1002/pu.31306","url":null,"abstract":"<p>Donepezil (generic) - Aricept (brand)</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 5","pages":"9-10"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cohort study suggests benefit of earlier initiation of clozapine 队列研究表明早期开始氯氮平的益处
The Brown University Psychopharmacology Update Pub Date : 2025-03-27 DOI: 10.1002/pu.31297
{"title":"Cohort study suggests benefit of earlier initiation of clozapine","authors":"","doi":"10.1002/pu.31297","DOIUrl":"https://doi.org/10.1002/pu.31297","url":null,"abstract":"<p>A population-based cohort study has found that among patients with first-episode schizophrenia who experienced a relapse, continuation of the same treatment or switching to a non-clozapine antipsychotic was not as effective as switching to clozapine in preventing a second relapse. The results call into question the recommendation in treatment guidelines to use clozapine only as third-line treatment. Study results were published in the February 2025 issue of <i>Lancet Psychiatry</i>.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 5","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Despite adverse event risk, anti psychotic polypharmacy has continued to rise 尽管存在不良事件风险，抗精神病药物的使用仍在持续增加
The Brown University Psychopharmacology Update Pub Date : 2025-03-27 DOI: 10.1002/pu.31298
{"title":"Despite adverse event risk, anti psychotic polypharmacy has continued to rise","authors":"","doi":"10.1002/pu.31298","DOIUrl":"https://doi.org/10.1002/pu.31298","url":null,"abstract":"<p>Concurrent use of two or more anti­psychotics has continued to increase over the past 50 years despite its association with a higher risk of adverse events, a systematic review and meta-analysis has found. In comparison with anti­psychotic monotherapy, polypharmacy was associated with higher risk of adverse outcomes such as relapse and psychiatric hospitalization. Results of the review and meta-analysis were published online Nov. 12, 2024, in <i>Lancet Psychiatry</i>.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 5","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychotropic-induced weight gain and telomere length 精神药物引起的体重增加和端粒长度
The Brown University Psychopharmacology Update Pub Date : 2025-03-27 DOI: 10.1002/pu.31299
Y. W. Francis Lam Pharm.D., FCCP
{"title":"Psychotropic-induced weight gain and telomere length","authors":"Y. W. Francis Lam Pharm.D., FCCP","doi":"10.1002/pu.31299","DOIUrl":"https://doi.org/10.1002/pu.31299","url":null,"abstract":"<p>Research suggests that shortening of telomeres, protective cap-like structures at the ends of chromosomes, as well as inflammation, are associated with decreased cellular lifespan, and as such have been implicated in several age-related medical conditions (Gavia-García et al., 2021). A meta-analysis has reported an association between shorter telomere length and several psychiatric conditions, including anxiety, bipolar disorder, depression, post-traumatic stress disorder, and psychosis (Darrow et al., 2016).</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 5","pages":"2-3"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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