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The Brown University Psychopharmacology Update最新文献

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Brexpiprazole-sertraline combination improves symptoms of PTSD 布雷哌唑-舍曲林联合治疗可改善PTSD症状
The Brown University Psychopharmacology Update Pub Date : 2025-03-03 DOI: 10.1002/pu.31285
{"title":"Brexpiprazole-sertraline combination improves symptoms of PTSD","authors":"","doi":"10.1002/pu.31285","DOIUrl":"https://doi.org/10.1002/pu.31285","url":null,"abstract":"<p>Combination treatment with brexpiprazole and sertraline was significantly more effective than sertraline plus placebo in reducing symptoms of post-traumatic stress disorder (PTSD) in adults, a Phase 3 study has found. The brexpiprazole-sertraline combination also showed good safety results in line with the safety profile of brexpiprazole. Study results were published online Dec. 18, 2024, in <i>JAMA Psychiatry</i>.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 4","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143533436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychotropic-induced lipid disturbances 精神药物引起的脂质紊乱
The Brown University Psychopharmacology Update Pub Date : 2025-03-03 DOI: 10.1002/pu.31286
Y. W. Francis Lam Pharm.D., FCCP
{"title":"Psychotropic-induced lipid disturbances","authors":"Y. W. Francis Lam Pharm.D., FCCP","doi":"10.1002/pu.31286","DOIUrl":"https://doi.org/10.1002/pu.31286","url":null,"abstract":"<p>Use of psychotropic drugs, especially but not only most second-generation antipsychotics, is associated with higher levels of lipids, posing an increased risk for developing cardiovascular disease (Pillinger et al., 2020). There is also evidence that plasma lipid levels and dyslipidemia are substantially impacted by clinical and genetic factors (Ramasamy, 2016).</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 4","pages":"2"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143533456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psilocybin therapy might help frontline pandemic workers 裸盖菇素治疗可能有助于一线疫情工作者
The Brown University Psychopharmacology Update Pub Date : 2025-03-03 DOI: 10.1002/pu.31292
{"title":"Psilocybin therapy might help frontline pandemic workers","authors":"","doi":"10.1002/pu.31292","DOIUrl":"https://doi.org/10.1002/pu.31292","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 4","pages":"7-8"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143533459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combining lisdexamfetamine and CBT improves outcomes in binge eating disorder 利地安非他明和CBT联合治疗可以改善暴食症的治疗效果
The Brown University Psychopharmacology Update Pub Date : 2025-03-03 DOI: 10.1002/pu.31288
{"title":"Combining lisdexamfetamine and CBT improves outcomes in binge eating disorder","authors":"","doi":"10.1002/pu.31288","DOIUrl":"https://doi.org/10.1002/pu.31288","url":null,"abstract":"<p>Combining lisdexamfetamine and cognitive-behavioral therapy (CBT) reduced binge eating behaviors to a greater extent than the individual treatments alone in patients with binge eating disorder and comorbid obesity, a 12-week randomized trial has found. The combined treatment also led to the greatest reductions in eating disorder psychopathology among the studied treatments.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 4","pages":"4-5"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143533534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Your Medication Information 您的用药信息
The Brown University Psychopharmacology Update Pub Date : 2025-03-03 DOI: 10.1002/pu.31296
{"title":"Your Medication Information","authors":"","doi":"10.1002/pu.31296","DOIUrl":"https://doi.org/10.1002/pu.31296","url":null,"abstract":"<p>Oxcarbazepine (generic) — Trileptal (brand)</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 4","pages":"9-10"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143533460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Guideline includes recommendations for initiating metformin with antipsychotic 指南包括建议开始使用二甲双胍与抗精神病药
The Brown University Psychopharmacology Update Pub Date : 2025-03-03 DOI: 10.1002/pu.31289
{"title":"Guideline includes recommendations for initiating metformin with antipsychotic","authors":"","doi":"10.1002/pu.31289","DOIUrl":"https://doi.org/10.1002/pu.31289","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 4","pages":"6-7"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143533535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stimulants, atomoxetine most efficacious in short term for adult ADHD 兴奋剂，阿托西汀短期内对成人多动症最有效
The Brown University Psychopharmacology Update Pub Date : 2025-03-03 DOI: 10.1002/pu.31295
{"title":"Stimulants, atomoxetine most efficacious in short term for adult ADHD","authors":"","doi":"10.1002/pu.31295","DOIUrl":"https://doi.org/10.1002/pu.31295","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 4","pages":"8"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143535871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychedelics and psychosis: Quantifying the risk 致幻剂和精神病：量化风险
The Brown University Psychopharmacology Update Pub Date : 2025-01-29 DOI: 10.1002/pu.31278
Lawrence H. Price M.D.
{"title":"Psychedelics and psychosis: Quantifying the risk","authors":"Lawrence H. Price M.D.","doi":"10.1002/pu.31278","DOIUrl":"https://doi.org/10.1002/pu.31278","url":null,"abstract":"<p>Just over a year ago, I somewhat reluctantly weighed in on the implications for psychiatry of the resurgent interest in psychedelic drugs (Price, 2024). In contrast to the “psychedelic era” of the 1960s and 1970s, this time public interest in these compounds has been accompanied by skillful politico-legal advocacy and systematic research. Both of those endeavors require high levels of funding, and both private philanthropic and for-profit pharmaceutical entities have, for better or worse, stepped in.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 3","pages":"7-8"},"PeriodicalIF":0.0,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143120851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Weight-loss drugs improve outcomes in patients with alcohol use disorder 减肥药物可改善酒精使用障碍患者的治疗效果
The Brown University Psychopharmacology Update Pub Date : 2025-01-29 DOI: 10.1002/pu.31274
{"title":"Weight-loss drugs improve outcomes in patients with alcohol use disorder","authors":"","doi":"10.1002/pu.31274","DOIUrl":"https://doi.org/10.1002/pu.31274","url":null,"abstract":"<p>Use of the glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide was associated with reduced risk of alcohol-related hospitalization in patients with alcohol use disorder (AUD), a cohort study has found. Both semaglutide and the GLP-1 receptor agonist liraglutide were associated with lower risk of hospitalization than use of medication treatments for AUD. Study results were published online Nov. 13, 2024, in <i>JAMA Psychiatry</i>.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 3","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143120842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Meta-analysis suggests safety of methylphenidate, atomoxetine in pregnancy 荟萃分析表明哌醋甲酯和阿托西汀在妊娠期的安全性
The Brown University Psychopharmacology Update Pub Date : 2025-01-29 DOI: 10.1002/pu.31279
{"title":"Meta-analysis suggests safety of methylphenidate, atomoxetine in pregnancy","authors":"","doi":"10.1002/pu.31279","DOIUrl":"https://doi.org/10.1002/pu.31279","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 3","pages":"6"},"PeriodicalIF":0.0,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143120852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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