Srpski arhiv za celokupno lekarstvo最新文献_第9页

Assessment of blood transfusion use during hospital treatment of COVID-19 patients - a single center experience 评估COVID-19患者住院治疗期间的输血使用情况——单中心经验

4区医学

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI: 10.2298/sarh231206102m

Vojislava Milutinovic, Mirjana Kovac, Bogdan Crnokrak, Marija Zdravkovic

{"title":"Assessment of blood transfusion use during hospital treatment of COVID-19 patients - a single center experience","authors":"Vojislava Milutinovic, Mirjana Kovac, Bogdan Crnokrak, Marija Zdravkovic","doi":"10.2298/sarh231206102m","DOIUrl":"https://doi.org/10.2298/sarh231206102m","url":null,"abstract":"Introduction/Objective. There is very limited data regarding the need for transfusion and its effect on the overall mortality of patients with coronavirus disease 2019 (COVID-19). The aim of our study is to determine the need for blood component transfusion in patents treated for COVID-19 infection. Methods. This retrospective observational study included 4,426 COVID-19 positive patients, who were treated, in the period between June 23, 2020, and May 2, 2021, at the Bezanijska Kosa University Hospital Medical Center. Of these patients, 826 were treated in the intensive care units of the hospital. Of the total number of patients, 326 (7.4%) received transfusions. The clinical presentation, the structure of the applied transfusion therapy, the laboratory parameters, and the treatment outcome were analyzed in this study. Results. Of the 828 patients treated in the intensive care units, 151 (18.2%) patients required transfusion, while transfusion was necessary in a total of 4.9% of patients treated in the hospital wards. Of the total number of all transfused patients, 86% received erythrocytes, one third of them received fresh frozen plasma, 10% received cryoprecipitate, while platelets were administered in around 6% of the patients. The mortality rate in the tested group was 46%. Conclusion. The frequency of the application of blood components was significantly higher in patients with a severe form of the disease. The presence of comorbidities did not affect the need for transfusion therapy. In the group of patients treated in the intensive care units, 85% received erythrocytes, 39% received fresh frozen plasma, 19% received cryoprecipitate and 7% received platelets.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135610237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The first human case of multilocular Echinococcosis recognized in Serbia 塞尔维亚发现首例人类多房棘球蚴病病例

4区医学

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI: 10.2298/sarh230112060l

Dusan Lalosevic, Mirjana Zivojinov, Valentina Isakovic, Dejan Ivanov, Vladan Trivunovic, Maja Ruzic

{"title":"The first human case of multilocular Echinococcosis recognized in Serbia","authors":"Dusan Lalosevic, Mirjana Zivojinov, Valentina Isakovic, Dejan Ivanov, Vladan Trivunovic, Maja Ruzic","doi":"10.2298/sarh230112060l","DOIUrl":"https://doi.org/10.2298/sarh230112060l","url":null,"abstract":"Introduction. Echinococcus multilocularis causes multilocular or alveolar echinococcosis, which differs from infection caused by Echinococcus granulosus in clinical presentation in humans. The most common definitive hosts for E. multilocularis are foxes and jackals, while domestic mammals like dogs and cats are rare. Humans are rare and accidental intermediate hosts. Cystic echinococcosis in humans is endemic in Serbia, while more severe alveolar echinococcosis has not yet been recorded. Case outline. We present a case of a 67-year-old female from a small village in the Sremska Mitrovica municipality. The onset of symptoms was several years ago, with liver pain which progressed over time. Differential diagnoses included benign liver tumors like haemangioma, cystic echinococcosis and abscess formed in the cystic echinococcal lesion. Left lateral hepatectomy was performed, and S II/III liver segments were removed. Pathological examination showed numerous small empty vesicle spaces with chitin membrane without protoscolices, surrounded by massive fibrosis and infiltrative growth into the liver parenchyma, all indicative marks of multilocular echinococcosis. Surgical margins were found positive for echinococcal vesicles showing that echinococcal tissue was not completely removed. Thus albendazole therapy was introduced. Epidemiological interview revealed that the patient lived in an endemic region of multilocular echinococcosis, in a house with two hunting dogs and backyard where contamination of soil with fox feces could occur. Conclusion. This is the first case of human multilocular echinococcosis recorded in Serbia, which should alert the medical community to improve prophylactic and diagnostic procedures and surgical techniques to better manage this zoonotic disease.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135686311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Can we distinguish conventional osteosarcoma subtypes (osteoblastic and chondroblastic) based on their magnetic resonance signal intensities? 我们能否根据其磁共振信号强度来区分常规骨肉瘤亚型(成骨细胞和软骨细胞)?

4区医学

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI: 10.2298/sarh220920085g

Sabriye Gülçin Bozbeyoğlu, Ayse Nur Toksoz Yildirim

{"title":"Can we distinguish conventional osteosarcoma subtypes (osteoblastic and chondroblastic) based on their magnetic resonance signal intensities?","authors":"Sabriye Gülçin Bozbeyoğlu, Ayse Nur Toksoz Yildirim","doi":"10.2298/sarh220920085g","DOIUrl":"https://doi.org/10.2298/sarh220920085g","url":null,"abstract":"Introduction/Objectives. Osteosarcoma (OS) is the most common primary malignant bone tumor in adolescents and young adults, with a tendency to produce variable amounts of osteoid, cartilage, and fibrous matrices. The objective of this study is to differentiate between osteosarcoma subtypes osteoblastic and chondroblastic according to their magnetic resonance (MR) signal intensities and X-ray findings. Methods. We performed a retrospective analysis for 21 pathologically proven osteosarcoma subtypes: osteoblastic (n = 14) and chondroblastic (n = 7). Conventional images of the bone of origin, periosteal reactions, lytic and sclerotic features, the presence of calcification, and pathological fractures were investigated with X-rays. We measured the mean ROI values for each lesion with MRI sequences. Results. Among the osteosarcoma lesions, 57% were localized at the knee. X-ray evaluations of the osteoblastic osteosarcomas revealed pure lytic lesions in 35.7% and pure sclerotic lesions in 35.7%. Chondroblastic osteosarcomas revealed pure lytic lesions in 14.3% and pure sclerotic lesions in 42.9%. Due to variable osteoblastic, chondroblastic, and fibroblastic areas and proportions of the ossified matrix, osteosarcoma lesions have a heterogeneous MR signal. However, no statistically significant value was detected. Conclusion. According to our results, MRI signal characteristics and X-ray findings may not be able to distinguish osteosarcoma subtypes, so prospective studies with larger patient cohorts are needed.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135840834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychiatric characteristics of homicide perpetrators in Serbia 塞尔维亚杀人案罪犯的精神特征

4区医学

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI: 10.2298/sarh220911088k

Vladimir Knezevic, Dragana Ratkovic, Svetlana Ivanovic-Kovacevic, Ana Vejnovic, Valentina Sobot, Masa Comic, Jelena Knezevic

{"title":"Psychiatric characteristics of homicide perpetrators in Serbia","authors":"Vladimir Knezevic, Dragana Ratkovic, Svetlana Ivanovic-Kovacevic, Ana Vejnovic, Valentina Sobot, Masa Comic, Jelena Knezevic","doi":"10.2298/sarh220911088k","DOIUrl":"https://doi.org/10.2298/sarh220911088k","url":null,"abstract":"Introduction/Objective. Homicide, a major public concern, has always attracted the attention of criminology, psychiatry, psychology, and other related disciplines. The objective of this study was to determine the frequency and type of mental disorders in 94 attempted-committed homicide perpetrators. Methods. The authors conducted a psychiatric assessment of all perpetrators based on psychiatric interviews, psychological testing, and the examination of available medical records. Results. The key findings of this study imply that there is a large percentage of violent crime perpetrators with mental disorders (62%). When we excluded people with personality disorders from this group, we found that the most common major mental disorders among the perpetrators were psychosis and alcohol use disorders (approximately 10% each). Conclusion. The results highlight the importance of the early identification and treatment of people with mental disorders in the general population, as this could reduce the possibility of criminal behavior. The high overall incidence of mental disorders in the group of homicide perpetrators indicates the need for a reform of psychiatric services in Serbia and the promotion of psychiatry in the community, which would contribute to bringing professionals closer to people with mental disorders and thus, timely recognition and treatment of these patients.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135841486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characteristics of patients with diagnosed chronic fungal rhinosinusitis surgically treated in the past five years 近五年来外科治疗的慢性真菌性鼻窦炎患者的特点

IF 0.2 4区医学

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI: 10.2298/sarh211016053b

Maja M Buljčik-Čupić, S. Savovic, S. Lemajic-Komazec, D. Dragičević, T. Tesic, I. Sivčev

{"title":"Characteristics of patients with diagnosed chronic fungal rhinosinusitis surgically treated in the past five years","authors":"Maja M Buljčik-Čupić, S. Savovic, S. Lemajic-Komazec, D. Dragičević, T. Tesic, I. Sivčev","doi":"10.2298/sarh211016053b","DOIUrl":"https://doi.org/10.2298/sarh211016053b","url":null,"abstract":"Introduction/Objective Fungal rhinosinusitis comprises of a wide range of immune-pathological responses, including invasive, chronic, granulomatous, and allergic diseases. Aim of this study was to determine total number of patients, their characteristics, frequency of symptoms, the manner of disease manifestation and the success of therapy. Methods Study included 21 patients with diagnosis FRS made according to the 2012 EPOS guidelines. Results Based on VAS(visual analogue scale), feeling of localized pressure, ie. facial pain was dominant in 9.57 ? 0.98, than the secretion from the nose is 8.14 ? 1.62, problem of the breathing on the nose in 6.67 ? 3.25, while reduction the sense of smell was in 2.14 ? 3.00. T-test showed there is a statistically significant difference between mucosal changes on the diseased and healthy sides of the patient's face (p <0.0001). Intraoperative in 18 (85.71%) patients only one sinus was affected. The most commonly affected sinus was maxillary, in 13 (54.17%) cases, followed by sphenoid sinus in 5 (20.83%) cases. As a cause of rhinosinusitis Aspergillus was proven in 12 (57.14%) patients. Conclusion The dominant symptom of patients with fungal rhinosinusitis was localized pain / pressure in the area of the affected sinus. Endoscopically, on the side of the affected sinus, the pathological mucosa with thick, pithy, mucous secretion dominated. The maxillary sinus is primarily unilaterally affected, in more than half of the patients. Aspergillus has been proven to be the most common cause of rhinosinusitis.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"15 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68726213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atypical clinical presentation of rheumatoid arthritis 类风湿性关节炎的非典型临床表现

IF 0.2 4区医学

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI: 10.2298/sarh220529081b

K. Boskovic, Aleksandra Savic, B. Erdeljan, S. Subin-Teodosijević, A. Glavcic

{"title":"Atypical clinical presentation of rheumatoid arthritis","authors":"K. Boskovic, Aleksandra Savic, B. Erdeljan, S. Subin-Teodosijević, A. Glavcic","doi":"10.2298/sarh220529081b","DOIUrl":"https://doi.org/10.2298/sarh220529081b","url":null,"abstract":"Introduction. Rheumatoid arthritis is a systemic autoimmune disease with inflammation of the joints as its hallmark. Extra-articular manifestations affect nearly half of the patients either at the onset of disease or later during the disease course. Case outline. A 43-year-old man complained over a chest pain, dry cough and fatigue. Diagnosis of pericarditis was made based on echocardiography findings. Due to worsening of respiratory symptoms he was admitted to the hospital. Initial diagnostic workup revealed elevated concentrations of acute phase reactants, pericardial effusion and bilateral pulmonary nodules. Pathohistological analysis of lung nodules ruled out malignancy and tuberculosis. He was treated with colhicine which led to a regression of a pericardial effusion. Afterwards, due to arthritis of the right wrist, high erythrocyte sedimentation rate and C-reactive protein, positive immunoserology and bone erosion at the distal ulna diagnosis of seropositive rheumatoid arthritis was established. He was treated with antimalarial, methotrexate and glucocorticoids until suffering from COVID-19 pneumonia which triggered arthritis flare. Owing to the loss of efficiency of combination therapy with methotrexate and glucocorticoid, baricitinib was added to the treatment. Low disease activity was achieved after 3 months of administering baricitinib and methotrexate, and no adverse events occurred during 20 months of this therapy. Conclusion. Every patient with pericarditis of unknown etiology should be diagnostically evaluated in term of connective tissue disease including rheumatoid arthritis, because the initial clinical presentation in some group of patients could lack characteristic synovitis.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68728897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cardiac surgery intensive care unit nursing workload assessment using nursing activities score 应用护理活动评分法评估心脏外科重症监护病房护理工作量

IF 0.2 4区医学

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI: 10.2298/sarh220729066s

N. Stojaković, Bojan Mihajlović, J. Ninkovic, Jovan Rajic, Jelena Vuckovic, M. Golubović, L. Velicki

{"title":"Cardiac surgery intensive care unit nursing workload assessment using nursing activities score","authors":"N. Stojaković, Bojan Mihajlović, J. Ninkovic, Jovan Rajic, Jelena Vuckovic, M. Golubović, L. Velicki","doi":"10.2298/sarh220729066s","DOIUrl":"https://doi.org/10.2298/sarh220729066s","url":null,"abstract":"Introduction/Objective. Nursing Activities Score (NAS) is one of the most accepted and widely used scores for assessing the workload of the nursing staff in regards of qualitative and quantitative adequacy. The aim of this study was to evaluate and analyze nursing workload in cardiac surgery intensive care unit (CSICU) using the NAS in a contemporary set of patients undergoing heart surgery. Methods. The study included 809 consecutive patients admitted to adult CSICU who had major cardiac surgery during the year of 2019. Demographic data were collected from medical records (gender, age, type of treatment, length of stay [LOS], and discharge), EuroSCORE II and NAS value. Results. The majority of patients underwent coronary (43.1%), valvular (32.6%) and combined (24.2%) cardiac surgery procedure. The average patient LOS in CSICU was 2.5 ? 3.4 days. The average NAS value in our sample was 100.8% ? 63.1%. NAS value during the first operative day was a poor marker of the outcome in terms of mortality (C-index 0.520, 95% CI - 0.422-0.617, p=0.676). Significant difference was observed in terms of average NAS value between the patients submitted to coronary surgery and combined surgery (p = 0.001). NAS has been shown to be useful for assessing activity in a CSICU, confirming the optimal workload of nurses, while higher NAS values in our hospital indicate increased workload compared to similar institutions. Conclusion. NAS provided viable information regarding the care and hospitalization of patients in a CSICU. In accordance to NAS, the optimal level of nursing workload was established in our hospital settings.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68729461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ileal leiomyosarcoma as a cause of small bowel obstruction 回肠平滑肌肉瘤是引起小肠梗阻的原因

IF 0.2 4区医学

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI: 10.2298/sarh220920063p

Jelena Pilipovic-Grubor, S. Stojanovic, Marija Grdinic, M. Živojinov, D. Petrović

{"title":"Ileal leiomyosarcoma as a cause of small bowel obstruction","authors":"Jelena Pilipovic-Grubor, S. Stojanovic, Marija Grdinic, M. Živojinov, D. Petrović","doi":"10.2298/sarh220920063p","DOIUrl":"https://doi.org/10.2298/sarh220920063p","url":null,"abstract":"Introduction. Ileal leiomyosarcoma is unusual form of malignant gastrointestinal tumor. Often insidious in clinical presentation, it frequently presents a diagnostic challenge. Occasionally, a correct diagnosis is finally established due to emergency situation. The aim of this study is to present the role of magnetic enterography in determining the precise cause of small bowel dilation. Case outline. A 59-year-old female patient presented with small bowel obstruction. Erect abdominal radiograph identified the presence of small bowel obstruction and excluded pneumoperitoneum. Non-contrast computed tomography of the abdomen and pelvis noted transitional zone in the region of terminal ileum with collapsed bowel lumen distal to the transitional point, without determined underlying cause. Magnetic resonance enterography observed obstructive intraluminal soft-tissue mass with fatty component sized up to 4 cm in terminal ileum, with mesenteric involvement. The abdominal surgeon revealed ileal intraluminal tumor which affected the locoregional mesentery and serosa of the adjacent bowel. Histological and immunohistochemical analysis confirmed the diagnosis of ileal leiomyosarcoma with involvement of wall serosa and mesenteric fat tissue. Conclusion. Magnetic resonance enterography is a reliable diagnostic tool for detection and diagnosis of malignant small bowel tumors. Sometimes, tumors manifest clinically as bowel obstruction. Surgical treatment is necessary, while histology and immunohistochemistry are crucial to confirm the diagnosis of small bowel leiomyosarcoma.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68729660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolism of the mother, placenta and fetus in diabetes 糖尿病中母体、胎盘和胎儿的代谢

IF 0.2 4区医学

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI: 10.2298/sarh221021012d

S. Dugalić, J. Todorović, Maja Macura, B. Gutic, Miloš Milinčić, Dragana D Božić, Milica Stojiljković, Milica Petronijevic, Luka de, I. Pantić, M. Perović, B. Parapid, M. Gojnić

引用次数: 0

Novel inflammatory markers and prognostic importance of platinum-sensitive ovarian carcinoma relapse 新的炎症标志物和铂敏感卵巢癌复发的预后重要性

IF 0.2 4区医学

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI: 10.2298/sarh221122057t

Fatih Tay, Mustafa Büyükkör, Öztürk Ateş

{"title":"Novel inflammatory markers and prognostic importance of platinum-sensitive ovarian carcinoma relapse","authors":"Fatih Tay, Mustafa Büyükkör, Öztürk Ateş","doi":"10.2298/sarh221122057t","DOIUrl":"https://doi.org/10.2298/sarh221122057t","url":null,"abstract":"Introduction/Objective. Ovarian carcinomas are the deadliest gynecological tumors. Despite advances in treatment options, survival rates are still not at the desired level. Since clinical signs are not typical in early-stage disease, 2/3rd of patients are diagnosed late. Carbohydrate Antigen 125 (CA125) does not have sufficient sensitivity and specificity in early-stage disease and early post-relapse progression. There is a need for a simple and cost-effective marker that correlates with CA125. For this purpose, we aimed to evaluate the potential of systemic inflammatory markers? as diagnostic aids. Methods. Patients with platinum-sensitive recurrent ovarian carcinomas were preferred because the treatment options were more diverse than the resistant group. Using retrospective data collection, 105 patients with platinum-sensitive recurrent ovarian carcinoma, admitted in the last four years were included in the study. Complete blood count data was recorded based on recurrence and progression periods. Results. When the systemic immune inflammatory index (SII) values were evaluated in combination with CA125 in terms of progression during the control visits after platinum-sensitive disease recurrence treatment, progression detection proportions increased to 97.5%, which was 82.9% when only CA125 was used. On the other hand, false positivity, which was 18.5% for CA125 alone, decreased to 2.5% when combined with SII. Furthermore, neutrophil lymphocyte ratio, WBC, and neutrophil values showed correlations with high CA125 values. Conclusion. The SII value could be used together with CA125 because it is easy to use, accessible, and has low cost in clinical practice, as well as to increase the accuracy rate and make precise corrections in the false positivity rate.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68730935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1