Srpski arhiv za celokupno lekarstvo最新文献_第8页

Comparison of diagnostic efficacy of the Abbott RealTime SARS-CoV-2 assay and the BGI real-time fluorescent RT-PCR kit for the RT-PCR-based detection of Severe Acute Respiratory Syndrome Coronavirus-2 雅培实时SARS-CoV-2检测试剂盒与华大基因实时荧光RT-PCR试剂盒检测严重急性呼吸综合征冠状病毒-2的诊断效果比较

IF 0.2 4区医学

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI: 10.2298/sarh230201074s

Jelena Stojčević-Maletić, I. Barjaktarović, Katarina Bačulov, V. Čabarkapa, V. Sakač, Z. Gojković

{"title":"Comparison of diagnostic efficacy of the Abbott RealTime SARS-CoV-2 assay and the BGI real-time fluorescent RT-PCR kit for the RT-PCR-based detection of Severe Acute Respiratory Syndrome Coronavirus-2","authors":"Jelena Stojčević-Maletić, I. Barjaktarović, Katarina Bačulov, V. Čabarkapa, V. Sakač, Z. Gojković","doi":"10.2298/sarh230201074s","DOIUrl":"https://doi.org/10.2298/sarh230201074s","url":null,"abstract":"Introduction/Objective. Based on the World Health Organization guidelines, the current \"gold standard\" to diagnose Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is reverse transcription-quantitative real-time polymerase chain reaction (RT-qPCR). The objective of this study was to compare and analyze the detection performance of two different authorized SARS-CoV-2 nucleic acid detection assays: the Abbott RealTime SARS-CoV-2 (ACOV) assay and the BGI Real-Time Fluorescent RT-PCR (BGI) kit. Methods. Our study included 384 randomly selected nasopharyngeal and oropharyngeal swabs previously tested by the ACOV and subsequently tested by the BGI kit for detecting SARS-CoV-2. All patients were adult individuals with symptoms or suspected of Coronavirus disease 2019 (COVID-19). Results. We found that the ACOV assay detected more cases of COVID-19 infection than the BGI assay. The positive percent agreement was 98.3% (95% confidence intervals (95% CI): 95.7-99.3%), while Cohen?s Kappa coefficient (Kappa) was 0.86 (95% CI: 0.80-0.91), indicating a strong level of agreement between these two tests. The negative percent agreement was 85.1% (95% CI: 78.3-90%), while 5.47% of cases were false negative using the BGI test to detect SARS-CoV-2. The sensitivity of the BGI test compared to Abbott was 91.73% (95% CI: 87.64-94.81%), and the specificity of the BGI test was 96.77% (95% CI: 91.95-99.11%). Conclusion. The Abbott kit showed a bit better diagnostic performance, and due to possible false negative results using the BGI test, we recommend complete testing with the ACOV test.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68731908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Resection of inferior vena cava leiomyosarcoma and reconstruction using ProxiCor patch 下腔静脉平滑肌肉瘤切除及ProxiCor贴片重建

IF 0.2 4区医学

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI: 10.2298/sarh230206069k

A. Karamarkovic, Vladica Cuk, J. Juloski

引用次数: 0

Concentrated triamcinolone acetonide suprachoroidally applied for the treatment of the diabetic macular oedema 浓缩曲安奈德黄斑上滴治疗糖尿病性黄斑水肿

IF 0.2 4区医学

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI: 10.2298/sarh211016051p

N. Petrovic, D. Todorović, Sunčica B Srećković, Mihailo Jovanović, Tatjana Sarenac-Vulovic

{"title":"Concentrated triamcinolone acetonide suprachoroidally applied for the treatment of the diabetic macular oedema","authors":"N. Petrovic, D. Todorović, Sunčica B Srećković, Mihailo Jovanović, Tatjana Sarenac-Vulovic","doi":"10.2298/sarh211016051p","DOIUrl":"https://doi.org/10.2298/sarh211016051p","url":null,"abstract":"Introduction/Objective The diabetic macular oedema is the accumulation of fluid in the macular tissue leading to its thickening. The aim of study was to evaluate the efficacy of concentrated Triamcinolone Acetonide 10mg/0.1ml injection into the suprachoroidal space in patients with diabetic macular oedema and decreased visual acuity. Methods In 12 eyes with diabetic macular oedema, without any prior treatment, using a small diameter 26G needle, an injection of 10mg/0.1ml Triamcinolone Acetonide was applied into the suprachoroidal space in the supero-temporal quadrant of the eye 4 mm from the limbus. Prior to the injection, as well as after 1,3,6,9 and 12 months after injection, visual acuity and intraocular pressure were measured, and central subfield thickness was recorded using Optical Coherence Tomography. Results After 1, 3, 6 and 9 post-injection months there was a statistically significant reduction in central subfield thickness (315.92 ?m, 257.66 ?m, 281.08?m and 295.51?m respectively) compared to baseline 447.67?m. At the end of the 12 month an increase in central subfield thickness was observed again 392.16?m. Visual acuity improved significantly from baseline (0.32) during the first 3 months (0.61) and remained stable until the end of the 9 month (0.51), but at the end of 12 months it decreased again (0.39). No significant intraocular pressure elevation and cataract development were observed in either eye during the entire follow-up period. Conclusion A single dose of 10 mg/0.1ml triamcinolone acetonide injected in suprachoroidal space can significantly stabilize diabetic macular oedema and maintain satisfactory visual acuity for up to 9 months.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68726060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preoperative embolization of juvenile nasopharyngeal angiofibroma using medium to large size particles 术前应用中~大颗粒栓塞青少年鼻咽血管纤维瘤

IF 0.2 4区医学

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI: 10.2298/sarh211127058n

D. Nestorovic, I. Nikolic, B. Pavlović, Saša Knežević, G. Tasic

{"title":"Preoperative embolization of juvenile nasopharyngeal angiofibroma using medium to large size particles","authors":"D. Nestorovic, I. Nikolic, B. Pavlović, Saša Knežević, G. Tasic","doi":"10.2298/sarh211127058n","DOIUrl":"https://doi.org/10.2298/sarh211127058n","url":null,"abstract":"Introduction. Juvenile nasopharyngeal angiofibroma are benign tumors, with locally aggressive behavior. Preoperative tumor embolization with polyvinyl alcohol particles can reduce intraoperative blood loss and facilitate surgical resection. Case outline. A 16-year-old male, was admitted to hospital due to profuse epistaxis and sense of nose fullness. MDCT examination showed a tumor mass in the right nasal cavity with extension to the right maxillary sinus and ethmoidal cells on the right, and in the left nasal cavity. It rested on the nasal septum, but without bone destruction. After application of contrast agent, described mass became intensely opacified. Preprocedural digital subtraction angiography of external and internal carotid arteries of both sides showed extensive pathological vascularization, which received main contribution from branches of maxillary artery on right and, to a lesser extent, on left side. Due to danger of penetration of a particle embolization agent of smaller diameter into orbital branches and possible retrograde migration into carotid artery, we decided to apply particle embolization agent of larger diameter (500-700 ??) than prescribed by modern standards. Tumor was completely surgically removed third day after embolization, and patient was discharged without any neurological deficit. Control contrast enhanced MDCT-s were performed at third and seventh month after surgery and showed no tumor residue or recurrence. Conclusion. The use of particles of larger diameter gave satisfactory results during operation - surgical excision of tumor, when dangerous anastomoses do not allow use of particles of smaller diameter and can be safely performed without significant neurological nor systemic complications.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68726766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of COVID-19 pandemic on pre-hospital and in-hospital time-dependent performance measures of treatment of patients with acute ischemic stroke - experience of a tertiary healthcare center COVID-19大流行对急性缺血性卒中患者院前和院内治疗时间依赖性绩效指标的影响——一家三级医疗保健中心的经验

IF 0.2 4区医学

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI: 10.2298/sarh220617062m

Lana Macura, Rea Mikulan, V. Padjen

{"title":"Impact of COVID-19 pandemic on pre-hospital and in-hospital time-dependent performance measures of treatment of patients with acute ischemic stroke - experience of a tertiary healthcare center","authors":"Lana Macura, Rea Mikulan, V. Padjen","doi":"10.2298/sarh220617062m","DOIUrl":"https://doi.org/10.2298/sarh220617062m","url":null,"abstract":"Introduction/Objective. The outbreak of COVID-19 pandemic has posed major challenges to the process of urgent care of patients with acute ischemic stroke (AIS) that requires optimal and well-coordinated pre- and in-hospital chains in order to enable recanalization therapy commencement the earliest possible. The study?s objection was to compare time-dependent performance measures and treatment results of patients with AIS hospitalized at a tertiary healthcare center before and during COVID 19 pandemic. Methods. Retrospective analysis was performed on AIS patients treated with recanalization therapy at Emergency Neurology Department of University Clinical Centre of Serbia, during the March-June period of years 2019, 2020, and 2021. Besides demographic and clinical characteristics, for each patient were calculated: time elapsed from stroke onset to hospital arrival (?onset-to-door\"), from hospitalization to the beginning of recanalization therapy (?door-to-needle\") and total time that elapsed from symptoms?s onset to treatment initiation (?onset-to-needle\"). Patients? functional outcome was assessed after three months by using modified Rankin scale (mRS) score. Results.Total of 84 patients were included (25/2019, 30/2020 and 29/2021; [p= 0.512]). No statistical significance was detected regarding age, gender, severity of stroke symptoms at hospital admission or type of received recanalization therapy. Our study showed no statistical difference regarding time needed to reach the hospital (p=0.441), ?door-to-needle\" time (p = 0.549), nor overall times elapsed from symptoms onset to therapy (p=0.481) among three groups of patients. Furthermore, comparison of patients? three-month functional outcomes didn?t show statistical significance (p = 0.922). Conclusion: This experienced tertiary healthcare system has shown notable resilience to the side-effects of COVID-19 pandemic.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68729306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characteristics of unintentional injuries in hospitalised children and adolescents - national retrospective study 住院儿童和青少年意外伤害的特点——全国回顾性研究

IF 0.2 4区医学

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI: 10.2298/sarh220929001j

Duška Jović, Snežana Petrović-Tepić, D. Knezevic, Aleksandar Tepić, S. Burgic, Vanja Radmanovic, M. Burgic-Radmanovic

{"title":"Characteristics of unintentional injuries in hospitalised children and adolescents - national retrospective study","authors":"Duška Jović, Snežana Petrović-Tepić, D. Knezevic, Aleksandar Tepić, S. Burgic, Vanja Radmanovic, M. Burgic-Radmanovic","doi":"10.2298/sarh220929001j","DOIUrl":"https://doi.org/10.2298/sarh220929001j","url":null,"abstract":"Introduction/Objective. Unintentional injuries is a global health issue among children and adolescents. The aim of this study was to examine the characteristics of unintentional injuries divided according to different age groups and sex among the children and adolescents who have been hospitalised in public hospitals of the Republic of Srpska, Bosnia and Herzegovina. Methods. A retrospective analysis of the e-base of the Agency for certification, accreditation and health care quality improvement of the Republic of Srpska data were collected from 10 public hospitals for patients aged ?19 years, who have been hospitalised for unintentional injuries in the period of January 2018 and December 2020. Results. The study identified 1,336 patients who were hospitalised for unintentional injuries, most of whom were boys (67.4%). Falls were the most frequent cause of hospitalisation in children of all age categories (aged 1 (70.6%), 1 to 4 (59.1%), 5 to 9 (68.5%)) and adolescents aged 10-14 (64.1%), while road traffic injuries were the leading cause of hospitalisation in adolescents aged 15 to 19 (62.6%). The cause of injury for the hospitalised patients were significantly related to age (p < 0.001) and sex (p < 0.05) groups. According to the nature of the injury in relation to the area of the body, the most frequent injuries were to the head (41.1%), caused by traffic accidents and falls. Conclusion. Since falls and road traffic injuries were the leading causes of hospitalisation, preventive measures should be taken to reduce the frequency of these injuries.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"41 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68729340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Abuse and addictive potential of pregabalin 普瑞巴林的滥用和成瘾性

IF 0.2 4区医学

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI: 10.2298/sarh220921070r

Dragana M. Ratković, V. Knežević, A. Dickov, Masa Comic, P. Savic

{"title":"Abuse and addictive potential of pregabalin","authors":"Dragana M. Ratković, V. Knežević, A. Dickov, Masa Comic, P. Savic","doi":"10.2298/sarh220921070r","DOIUrl":"https://doi.org/10.2298/sarh220921070r","url":null,"abstract":"Introduction. In the Republic of Serbia, pregabalin was marketed for the first time in 2006. Although the abuse of pregabalin has not been a common topic in the literature so far, it is often seen in everyday practice. Also, it seems that it is more common among addicts. Case outline. Mr. D. is a 41-year-old male patient, a perennial polytoxicomaniac on buprenorphine substitution therapy. He began using pregabalin because it caused euphoria and elevated mood, in daily doses which varies between 1050-2100 mg. The highest daily dose was 4200 mg. At the time he was admitted to the hospital for pregabalin detoxification, he met the general criteria for addiction syndrome. On admission, the patient was tense, anxious, irritable, drenched in sweat, and had insomnia. With an adequate dose of buprenorphine, the patient continued to complain about the reduction of the pregabalin dose and insisted on adjusting the dose. Shortly he was discharged from hospital at his personal request. After a month, during the check-up examination, he was diagnosed with a relapse of pregabalin use. He was readmitted to the hospital for detoxification treatment, the pregabalin dose was gradually reduced by 100 mg per week. After that the patient went to therapeutic community to continue treatment. Conclusion. This case indicates that practitioners have to be cautious when prescribing pregabalin to people prone to addiction. Further research is needed to identify risk factors for the development of pregabalin abuse syndrome, as well as to create clear guidelines for the treatment of abstinence syndrome.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68729724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges and suggestions for healthcare insurance of internal migrants in China 国内流动人口医疗保险面临的挑战与建议

IF 0.2 4区医学

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI: 10.2298/sarh221107059c

Zhao-Xin Chen

{"title":"Challenges and suggestions for healthcare insurance of internal migrants in China","authors":"Zhao-Xin Chen","doi":"10.2298/sarh221107059c","DOIUrl":"https://doi.org/10.2298/sarh221107059c","url":null,"abstract":"With its rapid social and economic development, China?s medical and healthcare services are also continually evolving. At present, China?s medical and healthcare field mainly comprises two aspects: service institutions and insurance systems. Healthcare insurance refers to the basic security system that provides medical services to the population and pays part of their remedial expenses by rationally organising financial resources. It is not only a safety net but also a social stabiliser for the population. It is also an important part of China?s medical and healthcare reform. Internal migrants are those who do not belong to the household registration system within a city?s jurisdiction and constantly move between districts. They primarily include temporary residents, people in transit and registered tourists. The main purpose of healthcare insurance is to meet the needs for medical funds in line with the current level of economic development. In short, it is a basic security system that grants people access to a doctor, regardless of their income. However, since internal migrants move between districts, it can be difficult to guarantee their healthcare insurance. Healthcare service needs of the internal floating population are constantly growing, but the coverage of remedial services provided by medical insurance is still not comprehensive, and the guarantee is not sufficient. We should solve the medical security problem of the internal floating population by improving the measures of transferring medical insurance, implementing a more reasonable medical insurance system for employees, lowering the threshold for participation and expanding the scope of assistance.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68730234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Therapeutic dilemmas in the management of a patient with long-term rheumatoid arthritis and severe clinical presentation of SARS-COV-2 infection 长期类风湿关节炎合并严重临床表现为SARS-COV-2感染患者的治疗困境

IF 0.2 4区医学

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI: 10.2298/sarh221204016j

T. Janković, A. Savić, J. Zvekic-Svorcan, A. Glavcic, K. Boskovic

{"title":"Therapeutic dilemmas in the management of a patient with long-term rheumatoid arthritis and severe clinical presentation of SARS-COV-2 infection","authors":"T. Janković, A. Savić, J. Zvekic-Svorcan, A. Glavcic, K. Boskovic","doi":"10.2298/sarh221204016j","DOIUrl":"https://doi.org/10.2298/sarh221204016j","url":null,"abstract":"Introduction. The objective of this case report is to present a clinical course of SARS-CoV-2 infection in a patient with long-term rheumatoid arthritis and concomitant rituximab therapy. Case outline. A 58-year-old female patient was diagnosed with seropositive rheumatoid arthritis at the age of 35. She was primarily prescribed chloroquine and glucocorticoid, afterwards methotrexate and biological agent - etanercept. Because of a secondary loss of response etanercept was switched to rituximab. She had 13 cycles of rituximab and the last was given on June 2020. In December 2020 she was hospitalized due to bilateral pneumonia and respiratory insufficiency. The results of the laboratory analysis revealed anemia, leukocytosis, thrombocytosis and markedly elevated C-reactive protein, procalcitonin, D-dimer, transaminases. The findings of the chest CT scan were consistent with COVID-19 pneumonia features with accompanying bilateral pleural effusion. The patient was treated with antibiotics, corticosteroids, tocilizumab, hepatoprotective, gastroprotective, oxygen therapy and parenteral anticoagulant. Three months after recovering from pneumonia, she developed arthritis flare, hence a JAK inhibitor, baricitinib, was started. Low disease activity was achieved with baricitinib monotherapy. Conclusion. Due to a risk of a severe COVID-19, a caution may be required when applying immunosuppressive therapy in patients with rheumatic diseases.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68731089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cardiac arrest and repeated ST-segment elevation caused by initially unrecognized coronary vasospasm 最初未被识别的冠状血管痉挛引起的心脏骤停和重复st段抬高

IF 0.2 4区医学

Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI: 10.2298/sarh230415072c

Neda Ćićarić, Djordje Stevanovic, Dušan Nikolić, V. Miloradovic

{"title":"Cardiac arrest and repeated ST-segment elevation caused by initially unrecognized coronary vasospasm","authors":"Neda Ćićarić, Djordje Stevanovic, Dušan Nikolić, V. Miloradovic","doi":"10.2298/sarh230415072c","DOIUrl":"https://doi.org/10.2298/sarh230415072c","url":null,"abstract":"Introduction. Coronary artery spasm (CAS) is defined as a transient vasoconstriction of an epicardial coronary artery with a total or subtotal vessel occlusion, causing myocardial ischemia. Although the overall incidence of CAS during coronary angiography is estimated to be between 0.3% and 1%, CAS remains an underdiagnosed and undertreated cause of acute cardiac events. Case outline. In this article, we report a case of a 62-year-old male presenting with cardiac arrest and repeated ST-segment elevations during chest pain episodes, caused by initially unrecognized CAS. Although percutaneous coronary intervention (PCI) is generally not recommended for the treatment of CAS, due to clinical manifestations and the presence of underlying flow-limiting stenosis, we decided to perform PCI of the left anterior descending coronary artery. During the two-year-follow up period, the patient reported no chest pains nor exercise limitations at regular outpatient controls. Conclusion. Coronary artery spasms should be considered an unrecognized cause of refractory angina, acute coronary syndrome, malignant arrhythmia, and even cardiac arrest. Although medical therapy is the first option for CAS treatment, PCI could be a safe and effective approach in selected patients.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68732418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0