Sensors (Basel, Switzerland)最新文献

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An Integrated Smart Pond Water Quality Monitoring and Fish Farming Recommendation Aquabot System 智能池塘水质监测和养鱼综合推荐 Aquabot 系统
Sensors (Basel, Switzerland) Pub Date : 2024-06-01 DOI: 10.3390/s24113682
Md. Moniruzzaman Hemal, Atiqur Rahman, Nurjahan, Farhana Islam, Samsuddin Ahmed, M. S. Kaiser, Muhammad Raisuddin Ahmed
{"title":"An Integrated Smart Pond Water Quality Monitoring and Fish Farming Recommendation Aquabot System","authors":"Md. Moniruzzaman Hemal, Atiqur Rahman, Nurjahan, Farhana Islam, Samsuddin Ahmed, M. S. Kaiser, Muhammad Raisuddin Ahmed","doi":"10.3390/s24113682","DOIUrl":"https://doi.org/10.3390/s24113682","url":null,"abstract":"The integration of cutting-edge technologies such as the Internet of Things (IoT), robotics, and machine learning (ML) has the potential to significantly enhance the productivity and profitability of traditional fish farming. Farmers using traditional fish farming methods incur enormous economic costs owing to labor-intensive schedule monitoring and care, illnesses, and sudden fish deaths. Another ongoing issue is automated fish species recommendation based on water quality. On the one hand, the effective monitoring of abrupt changes in water quality may minimize the daily operating costs and boost fish productivity, while an accurate automatic fish recommender may aid the farmer in selecting profitable fish species for farming. In this paper, we present AquaBot, an IoT-based system that can automatically collect, monitor, and evaluate the water quality and recommend appropriate fish to farm depending on the values of various water quality indicators. A mobile robot has been designed to collect parameter values such as the pH, temperature, and turbidity from all around the pond. To facilitate monitoring, we have developed web and mobile interfaces. For the analysis and recommendation of suitable fish based on water quality, we have trained and tested several ML algorithms, such as the proposed custom ensemble model, random forest (RF), support vector machine (SVM), decision tree (DT), K-nearest neighbor (KNN), logistic regression (LR), bagging, boosting, and stacking, on a real-time pond water dataset. The dataset has been preprocessed with feature scaling and dataset balancing. We have evaluated the algorithms based on several performance metrics. In our experiment, our proposed ensemble model has delivered the best result, with 94% accuracy, 94% precision, 94% recall, a 94% F1-score, 93% MCC, and the best AUC score for multi-class classification. Finally, we have deployed the best-performing model in a web interface to provide cultivators with recommendations for suitable fish farming. Our proposed system is projected to not only boost production and save money but also reduce the time and intensity of the producer’s manual labor.","PeriodicalId":221960,"journal":{"name":"Sensors (Basel, Switzerland)","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141415296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of Appropriate Scaling of Networks and Images for Convolutional Neural Network-Based Nerve Detection in Ultrasound-Guided Nerve Blocks 研究基于卷积神经网络的超声引导神经阻滞中神经检测的网络和图像的适当缩放比例
Sensors (Basel, Switzerland) Pub Date : 2024-06-01 DOI: 10.3390/s24113696
T. Sugino, Shinya Onogi, Rieko Oishi, Chie Hanayama, Satoki Inoue, Shinjiro Ishida, Yuhang Yao, Nobuhiro Ogasawara, Masahiro Murakawa, Yoshikazu Nakajima
{"title":"Investigation of Appropriate Scaling of Networks and Images for Convolutional Neural Network-Based Nerve Detection in Ultrasound-Guided Nerve Blocks","authors":"T. Sugino, Shinya Onogi, Rieko Oishi, Chie Hanayama, Satoki Inoue, Shinjiro Ishida, Yuhang Yao, Nobuhiro Ogasawara, Masahiro Murakawa, Yoshikazu Nakajima","doi":"10.3390/s24113696","DOIUrl":"https://doi.org/10.3390/s24113696","url":null,"abstract":"Ultrasound imaging is an essential tool in anesthesiology, particularly for ultrasound-guided peripheral nerve blocks (US-PNBs). However, challenges such as speckle noise, acoustic shadows, and variability in nerve appearance complicate the accurate localization of nerve tissues. To address this issue, this study introduces a deep convolutional neural network (DCNN), specifically Scaled-YOLOv4, and investigates an appropriate network model and input image scaling for nerve detection on ultrasound images. Utilizing two datasets, a public dataset and an original dataset, we evaluated the effects of model scale and input image size on detection performance. Our findings reveal that smaller input images and larger model scales significantly improve detection accuracy. The optimal configuration of model size and input image size not only achieved high detection accuracy but also demonstrated real-time processing capabilities.","PeriodicalId":221960,"journal":{"name":"Sensors (Basel, Switzerland)","volume":"11 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141392340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of a Personalized Multiclass Classification Model to Detect Blood Pressure Variations Associated with Physical or Cognitive Workload 开发个性化多分类模型,检测与体力或认知工作量相关的血压变化
Sensors (Basel, Switzerland) Pub Date : 2024-06-01 DOI: 10.3390/s24113697
Andrea Valerio, D. Demarchi, Brendan O’Flynn, Paolo Motto Ros, Salvatore Tedesco
{"title":"Development of a Personalized Multiclass Classification Model to Detect Blood Pressure Variations Associated with Physical or Cognitive Workload","authors":"Andrea Valerio, D. Demarchi, Brendan O’Flynn, Paolo Motto Ros, Salvatore Tedesco","doi":"10.3390/s24113697","DOIUrl":"https://doi.org/10.3390/s24113697","url":null,"abstract":"Comprehending the regulatory mechanisms influencing blood pressure control is pivotal for continuous monitoring of this parameter. Implementing a personalized machine learning model, utilizing data-driven features, presents an opportunity to facilitate tracking blood pressure fluctuations in various conditions. In this work, data-driven photoplethysmograph features extracted from the brachial and digital arteries of 28 healthy subjects were used to feed a random forest classifier in an attempt to develop a system capable of tracking blood pressure. We evaluated the behavior of this latter classifier according to the different sizes of the training set and degrees of personalization used. Aggregated accuracy, precision, recall, and F1-score were equal to 95.1%, 95.2%, 95%, and 95.4% when 30% of a target subject’s pulse waveforms were combined with five randomly selected source subjects available in the dataset. Experimental findings illustrated that incorporating a pre-training stage with data from different subjects made it viable to discern morphological distinctions in beat-to-beat pulse waveforms under conditions of cognitive or physical workload.","PeriodicalId":221960,"journal":{"name":"Sensors (Basel, Switzerland)","volume":"59 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141408595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computer Vision and Augmented Reality for Human-Centered Fatigue Crack Inspection 计算机视觉和增强现实技术用于以人为本的疲劳裂纹检测
Sensors (Basel, Switzerland) Pub Date : 2024-06-01 DOI: 10.3390/s24113685
Rushil Mojidra, Jian Li, Ali Mohammadkhorasani, Fernando Moreu, C. Bennett, William N. Collins
{"title":"Computer Vision and Augmented Reality for Human-Centered Fatigue Crack Inspection","authors":"Rushil Mojidra, Jian Li, Ali Mohammadkhorasani, Fernando Moreu, C. Bennett, William N. Collins","doi":"10.3390/s24113685","DOIUrl":"https://doi.org/10.3390/s24113685","url":null,"abstract":"A significant percentage of bridges in the United States are serving beyond their 50-year design life, and many of them are in poor condition, making them vulnerable to fatigue cracks that can result in catastrophic failure. However, current fatigue crack inspection practice based on human vision is time-consuming, labor intensive, and prone to error. We present a novel human-centered bridge inspection methodology to enhance the efficiency and accuracy of fatigue crack detection by employing advanced technologies including computer vision and augmented reality (AR). In particular, a computer vision-based algorithm is developed to enable near-real-time fatigue crack detection by analyzing structural surface motion in a short video recorded by a moving camera of the AR headset. The approach monitors structural surfaces by tracking feature points and measuring variations in distances between feature point pairs to recognize the motion pattern associated with the crack opening and closing. Measuring distance changes between feature points, as opposed to their displacement changes before this improvement, eliminates the need of camera motion compensation and enables reliable and computationally efficient fatigue crack detection using the nonstationary AR headset. In addition, an AR environment is created and integrated with the computer vision algorithm. The crack detection results are transmitted to the AR headset worn by the bridge inspector, where they are converted into holograms and anchored on the bridge surface in the 3D real-world environment. The AR environment also provides virtual menus to support human-in-the-loop decision-making to determine optimal crack detection parameters. This human-centered approach with improved visualization and human–machine collaboration aids the inspector in making well-informed decisions in the field in a near-real-time fashion. The proposed crack detection method is comprehensively assessed using two laboratory test setups for both in-plane and out-of-plane fatigue cracks. Finally, using the integrated AR environment, a human-centered bridge inspection is conducted to demonstrate the efficacy and potential of the proposed methodology.","PeriodicalId":221960,"journal":{"name":"Sensors (Basel, Switzerland)","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141399542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electrochemical Diffusion Study in Poly(Ethylene Glycol) Dimethacrylate-Based Hydrogels 聚(乙二醇)二甲基丙烯酸酯水凝胶中的电化学扩散研究
Sensors (Basel, Switzerland) Pub Date : 2024-06-01 DOI: 10.3390/s24113678
E. Melnik, Steffen Kurzhals, G. Mutinati, Valerio Beni, Rainer Hainberger
{"title":"Electrochemical Diffusion Study in Poly(Ethylene Glycol) Dimethacrylate-Based Hydrogels","authors":"E. Melnik, Steffen Kurzhals, G. Mutinati, Valerio Beni, Rainer Hainberger","doi":"10.3390/s24113678","DOIUrl":"https://doi.org/10.3390/s24113678","url":null,"abstract":"Hydrogels are of great importance for functionalizing sensors and microfluidics, and poly(ethylene glycol) dimethacrylate (PEG-DMA) is often used as a viscosifier for printable hydrogel precursor inks. In this study, 1–10 kDa PEG-DMA based hydrogels were characterized by gravimetric and electrochemical methods to investigate the diffusivity of small molecules and proteins. Swelling ratios (SRs) of 14.43–9.24, as well as mesh sizes ξ of 3.58–6.91 nm were calculated, and it was found that the SR correlates with the molar concentration of PEG-DMA in the ink (MCI) (SR = 0.1127 × MCI + 8.3256, R2 = 0.9692) and ξ correlates with the molecular weight (Mw) (ξ = 0.3382 × Mw + 3.638, R2 = 0.9451). To investigate the sensing properties, methylene blue (MB) and MB-conjugated proteins were measured on electrochemical sensors with and without hydrogel coating. It was found that on sensors with 10 kDa PEG-DMA hydrogel modification, the DPV peak currents were reduced to 92 % for MB, 73 % for MB-BSA, and 23 % for MB-IgG. To investigate the diffusion properties of MB(-conjugates) in hydrogels with 1–10 kDa PEG-DMA, diffusivity was calculated from the current equation. It was found that diffusivity increases with increasing ξ. Finally, the release of MB-BSA was detected after drying the MB-BSA-containing hydrogel, which is a promising result for the development of hydrogel-based reagent reservoirs for biosensing.","PeriodicalId":221960,"journal":{"name":"Sensors (Basel, Switzerland)","volume":"1995 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141400869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transformable Quadruped Wheelchairs Capable of Autonomous Stair Ascent and Descent 能自主上下楼梯的可变形四足轮椅
Sensors (Basel, Switzerland) Pub Date : 2024-06-01 DOI: 10.3390/s24113675
Atsuki Akamisaka, Katashi Nagao
{"title":"Transformable Quadruped Wheelchairs Capable of Autonomous Stair Ascent and Descent","authors":"Atsuki Akamisaka, Katashi Nagao","doi":"10.3390/s24113675","DOIUrl":"https://doi.org/10.3390/s24113675","url":null,"abstract":"Despite advancements in creating barrier-free environments, many buildings still have stairs, making accessibility a significant concern for wheelchair users, the majority of whom check for accessibility information before venturing out. This paper focuses on developing a transformable quadruped wheelchair to address the mobility challenges posed by stairs and steps for wheelchair users. The wheelchair, inspired by the Unitree B2 quadruped robot, combines wheels for flat surfaces and robotic legs for navigating stairs and is equipped with advanced sensors and force detectors to interact with its surroundings effectively. This research utilized reinforcement learning, specifically curriculum learning, to teach the wheelchair stair-climbing skills, with progressively increasing complexity in a simulated environment crafted in the Unity game engine. The experiments demonstrated high success rates in both stair ascent and descent, showcasing the wheelchair’s potential in overcoming mobility barriers. However, the current model faces limitations in tackling various stair types, like spiral staircases, and requires further enhancements in safety and stability, particularly in the descending phase. The project illustrates a significant step towards enhancing mobility for wheelchair users, aiming to broaden their access to diverse environments. Continued improvements and testing are essential to ensure the wheelchair’s adaptability and safety across different terrains and situations, underlining the ongoing commitment to technological innovation in aiding individuals with mobility impairments.","PeriodicalId":221960,"journal":{"name":"Sensors (Basel, Switzerland)","volume":"10 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141396992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lightweight Ghost Enhanced Feature Attention Network: An Efficient Intelligent Fault Diagnosis Method under Various Working Conditions 轻量级幽灵增强型特征注意网络:各种工作条件下的高效智能故障诊断方法
Sensors (Basel, Switzerland) Pub Date : 2024-06-01 DOI: 10.3390/s24113691
Huaihao Dong, Kai Zheng, Siguo Wen, Zheng Zhang, Yuyan Li, Bobin Zhu
{"title":"Lightweight Ghost Enhanced Feature Attention Network: An Efficient Intelligent Fault Diagnosis Method under Various Working Conditions","authors":"Huaihao Dong, Kai Zheng, Siguo Wen, Zheng Zhang, Yuyan Li, Bobin Zhu","doi":"10.3390/s24113691","DOIUrl":"https://doi.org/10.3390/s24113691","url":null,"abstract":"Recent advancements in applications of deep neural network for bearing fault diagnosis under variable operating conditions have shown promising outcomes. However, these approaches are limited in practical applications due to the complexity of neural networks, which require substantial computational resources, thereby hindering the advancement of automated diagnostic tools. To overcome these limitations, this study introduces a new fault diagnosis framework that incorporates a tri-channel preprocessing module for multidimensional feature extraction, coupled with an innovative diagnostic architecture known as the Lightweight Ghost Enhanced Feature Attention Network (GEFA-Net). This system is adept at identifying rolling bearing faults across diverse operational conditions. The FFE module utilizes advanced techniques such as Fast Fourier Transform (FFT), Frequency Weighted Energy Operator (FWEO), and Signal Envelope Analysis to refine signal processing in complex environments. Concurrently, GEFA-Net employs the Ghost Module and the Efficient Pyramid Squared Attention (EPSA) mechanism, which enhances feature representation and generates additional feature maps through linear operations, thereby reducing computational demands. This methodology not only significantly lowers the parameter count of the model, promoting a more streamlined architectural framework, but also improves diagnostic speed. Additionally, the model exhibits enhanced diagnostic accuracy in challenging conditions through the effective synthesis of local and global data contexts. Experimental validation using datasets from the University of Ottawa and our dataset confirms that the framework not only achieves superior diagnostic accuracy but also reduces computational complexity and accelerates detection processes. These findings highlight the robustness of the framework for bearing fault diagnosis under varying operational conditions, showcasing its broad applicational potential in industrial settings. The parameter count was decreased by 63.74% compared to MobileVit, and the recorded diagnostic accuracies were 98.53% and 99.98% for the respective datasets.","PeriodicalId":221960,"journal":{"name":"Sensors (Basel, Switzerland)","volume":"71 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141408518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Novel Methodology for Measuring Ambient Thermal Effects on Machine Tools 测量环境热效应对机床影响的新方法
Sensors (Basel, Switzerland) Pub Date : 2024-04-01 DOI: 10.3390/s24072380
F. Egaña, U. Mutilba, J. Yagüe-Fabra, E. Gomez-Acedo
{"title":"A Novel Methodology for Measuring Ambient Thermal Effects on Machine Tools","authors":"F. Egaña, U. Mutilba, J. Yagüe-Fabra, E. Gomez-Acedo","doi":"10.3390/s24072380","DOIUrl":"https://doi.org/10.3390/s24072380","url":null,"abstract":"Large machine tools are critically affected by ambient temperature fluctuations, impacting their performance and the quality of machined products. Addressing the challenge of accurately measuring thermal effects on machine structures, this study introduces the Machine Tool Integrated Inverse Multilateration method. This method offers a precise approach for assessing geometric error parameters throughout a machine’s working volume, featuring a low level of uncertainty and high speed suitable for effective temperature change monitoring. A significant innovation is found in the capability to automatically realise the volumetric error characterisation of medium- to large-sized machine tools at intervals of 40–60 min with a measurement uncertainty of 10 µm. This enables the detailed study of thermal errors which are generated due to variations in ambient temperature over extended periods. To validate the method, an extensive experimental campaign was conducted on a ZAYER Arion G™ large machine tool using a LEICA AT960™ laser tracker with four wide-angle retro-reflectors under natural workshop conditions. This research identified two key thermal scenarios, quasi-stationary and changing environments, providing valuable insights into how temperature variations influence machine behaviour. This novel method facilitates the optimization of machine tool operations and the improvement of product quality in industrial environments, marking a significant advancement in manufacturing metrology.","PeriodicalId":221960,"journal":{"name":"Sensors (Basel, Switzerland)","volume":"133 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140760209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cyber–Physical Systems for High-Performance Machining of Difficult to Cut Materials in I5.0 Era—A Review 面向 I5.0 时代难切削材料高性能加工的网络物理系统--综述
Sensors (Basel, Switzerland) Pub Date : 2024-04-01 DOI: 10.3390/s24072324
Hossein Gohari, Mahmoud Hassan, Bin Shi, Ahmad Sadek, Helmi Attia, Rachid M’Saoubi
{"title":"Cyber–Physical Systems for High-Performance Machining of Difficult to Cut Materials in I5.0 Era—A Review","authors":"Hossein Gohari, Mahmoud Hassan, Bin Shi, Ahmad Sadek, Helmi Attia, Rachid M’Saoubi","doi":"10.3390/s24072324","DOIUrl":"https://doi.org/10.3390/s24072324","url":null,"abstract":"The fifth Industrial revolution (I5.0) prioritizes resilience and sustainability, integrating cognitive cyber-physical systems and advanced technologies to enhance machining processes. Numerous research studies have been conducted to optimize machining operations by identifying and reducing sources of uncertainty and estimating the optimal cutting parameters. Virtual modeling and Tool Condition Monitoring (TCM) methodologies have been developed to assess the cutting states during machining processes. With a precise estimation of cutting states, the safety margin necessary to deal with uncertainties can be reduced, resulting in improved process productivity. This paper reviews the recent advances in high-performance machining systems, with a focus on cyber-physical models developed for the cutting operation of difficult-to-cut materials using cemented carbide tools. An overview of the literature and background on the advances in offline and online process optimization approaches are presented. Process optimization objectives such as tool life utilization, dynamic stability, enhanced productivity, improved machined part quality, reduced energy consumption, and carbon emissions are independently investigated for these offline and online optimization methods. Addressing the critical objectives and constraints prevalent in industrial applications, this paper explores the challenges and opportunities inherent to developing a robust cyber–physical optimization system.","PeriodicalId":221960,"journal":{"name":"Sensors (Basel, Switzerland)","volume":"339 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140763689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Colorectal Cancer Diagnosis through Breath Test Using a Portable Breath Analyzer—Preliminary Data 使用便携式呼气分析仪通过呼气测试诊断大肠癌--初步数据
Sensors (Basel, Switzerland) Pub Date : 2024-04-01 DOI: 10.3390/s24072343
A. Picciariello, A. Dezi, L. Vincenti, M. Spampinato, Wenzhe Zang, Pamela Riahi, Jared Scott, Ruchi Sharma, Xudong Fan, D. Altomare
{"title":"Colorectal Cancer Diagnosis through Breath Test Using a Portable Breath Analyzer—Preliminary Data","authors":"A. Picciariello, A. Dezi, L. Vincenti, M. Spampinato, Wenzhe Zang, Pamela Riahi, Jared Scott, Ruchi Sharma, Xudong Fan, D. Altomare","doi":"10.3390/s24072343","DOIUrl":"https://doi.org/10.3390/s24072343","url":null,"abstract":"Screening methods available for colorectal cancer (CRC) to date are burdened by poor reliability and low patient adherence and compliance. An altered pattern of volatile organic compounds (VOCs) in exhaled breath has been proposed as a non-invasive potential diagnostic tool for distinguishing CRC patients from healthy controls (HC). The aim of this study was to evaluate the reliability of an innovative portable device containing a micro-gas chromatograph in enabling rapid, on-site CRC diagnosis through analysis of patients’ exhaled breath. In this prospective trial, breath samples were collected in a tertiary referral center of colorectal surgery, and analysis of the chromatograms was performed by the Biomedical Engineering Department. The breath of patients with CRC and HC was collected into Tedlar bags through a Nafion filter and mouthpiece with a one-way valve. The breath samples were analyzed by an automated portable gas chromatography device. Relevant volatile biomarkers and discriminant chromatographic peaks were identified through machine learning, linear discriminant analysis and principal component analysis. A total of 68 subjects, 36 patients affected by histologically proven CRC with no evidence of metastases and 32 HC with negative colonoscopies, were enrolled. After testing a training set (18 CRC and 18 HC) and a testing set (18 CRC and 14 HC), an overall specificity of 87.5%, sensitivity of 94.4% and accuracy of 91.2% in identifying CRC patients was found based on three VOCs. Breath biopsy may represent a promising non-invasive method of discriminating CRC patients from HC.","PeriodicalId":221960,"journal":{"name":"Sensors (Basel, Switzerland)","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140756532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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