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Disparities in perioperative mortality outcomes between First Nations and non-First Nations peoples in Australia: protocol for a systematic review and planned meta-analysis. 澳大利亚原住民与非原住民围手术期死亡率结果的差异:系统综述和计划荟萃分析协议。
IF 6.3 4区 医学
Systematic Reviews Pub Date : 2024-08-05 DOI: 10.1186/s13643-024-02611-3
Edith B Waugh, Matthew J L Hare, David A Story, Lorena Romero, Mark Mayo, Heidi Smith-Vaughan, Jennifer R Reilly
{"title":"Disparities in perioperative mortality outcomes between First Nations and non-First Nations peoples in Australia: protocol for a systematic review and planned meta-analysis.","authors":"Edith B Waugh, Matthew J L Hare, David A Story, Lorena Romero, Mark Mayo, Heidi Smith-Vaughan, Jennifer R Reilly","doi":"10.1186/s13643-024-02611-3","DOIUrl":"10.1186/s13643-024-02611-3","url":null,"abstract":"<p><strong>Background: </strong>Health inequities persist among First Nations people living in developed countries. Surgical care is pivotal in addressing a significant portion of the global disease burden. Evidence regarding surgical outcomes among First Nations people in Australia is limited. The perioperative mortality rate (POMR) indicates timely access to safe surgery and predicts long-term survival after major surgery. This systematic review will examine POMR among First Nations and non-First Nations peoples in Australia.</p><p><strong>Methods: </strong>A systematic search strategy using MEDLINE, Embase, Emcare, Global Health, and Scopus will identify studies that include First Nations people and non-First Nations people who underwent a surgical intervention under anaesthesia in Australia. The primary focus will be on documenting perioperative mortality outcomes. Title and abstract screening and full-text review will be conducted by independent reviewers, followed by data extraction and bias assessment using the ROBINS-E tool. Meta-analysis will be considered if there is sufficient homogeneity between studies. The quality of cumulative evidence will be evaluated following the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) criteria.</p><p><strong>Discussion: </strong>This protocol describes the comprehensive methodology for the proposed systematic review. Evaluating disparities in perioperative mortality rates between First Nations and non-First Nations people remains essential in shaping the discourse surrounding health equity, particularly in addressing the surgical burden of disease.</p><p><strong>Systematic review registration: </strong>PROSPERO CRD42021258970.</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"208"},"PeriodicalIF":6.3,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11299354/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141894400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The outcomes of paediatric cataract surgery with intraocular lens insertion in sub-Saharan Africa: a systematic review. 撒哈拉以南非洲地区小儿白内障手术与眼内人工晶体植入术的结果:系统性综述。
IF 6.3 4区 医学
Systematic Reviews Pub Date : 2024-08-02 DOI: 10.1186/s13643-024-02607-z
Priscilla Princess Mhango, Thokozani Linda Zungu, Harold Ismael Nkume, Alinune Musopole, Shaffi Yusuf Mdala
{"title":"The outcomes of paediatric cataract surgery with intraocular lens insertion in sub-Saharan Africa: a systematic review.","authors":"Priscilla Princess Mhango, Thokozani Linda Zungu, Harold Ismael Nkume, Alinune Musopole, Shaffi Yusuf Mdala","doi":"10.1186/s13643-024-02607-z","DOIUrl":"10.1186/s13643-024-02607-z","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Importance: &lt;/strong&gt;Cataract is one of the leading causes of childhood blindness in Africa. The management of this condition requires timely surgical extraction of the cataractous lens with immediate optical correction and long-term follow-up to monitor visual improvement and manage complications that may arise. This review provides an opportunity to benchmark outcomes and to shed light on the reasons for those outcomes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objectives: &lt;/strong&gt;To review the published literature and report on the outcomes of paediatric cataract surgery with intraocular lens insertion in sub-Saharan Africa.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Data source: &lt;/strong&gt;The EMBASE, PubMed, Scopus, and Web of Science were searched for relevant articles.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Study selection: &lt;/strong&gt;We included all published primary studies from sub-Saharan Africa on cataract surgery outcomes in children aged 0-16 years with primary intraocular lens implantation conducted between 1990 and 2020. Eligible studies were those published in English or for which an English translation was available. In addition, reviewers screened the reference lists of all studies included in the full-text review for eligible studies. During the review, studies fitting the inclusion criteria above except for having been conducted in middle and high-income countries were tagged and placed in a comparison arm.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Data extraction and synthesis: &lt;/strong&gt;Study eligibility was determined by two independent reviewers, and data extraction was conducted by one reviewer with entries checked for accuracy by another reviewer. Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines for data synthesis were followed. The Joanna Briggs Institute (JBI) critical appraisal checklist was used for quality appraisal of the studies. The statistical software R was used in the analysis, and data were pooled using a random-effects model. Forest plots were generated using the R package 'metafor'.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Main outcomes and measures: &lt;/strong&gt;The primary outcome was visual acuity (VA) after cataract surgery and the proportions of eyes that achieved good, borderline, or poor visual outcome according to the World Health Organisation (WHO) categorisation of post-operative visual acuity. The secondary outcome measures reported included lag time to surgery, rates of follow-up, and rate of complications.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Eight out of 4763 studies were eligible for inclusion in this review, and seven were included in the quantitative analysis. There was a male preponderance in the study population, and the mean age at the time of cataract surgery ranged from 3.4 to 8.4 years. Visual outcomes were available for short-term visual outcomes (1 to 6 months) as the studies had a significant loss to follow-up. The pooled proportion of eyes that achieved a good visual acuity (i.e. equal to or greater than 6/18) in the short-term period was 31% (CI, 20-42). The comparative studies","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"204"},"PeriodicalIF":6.3,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11295353/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141879503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Automation of duplicate record detection for systematic reviews: Deduplicator. 系统综述重复记录检测自动化:Deduplicator.
IF 6.3 4区 医学
Systematic Reviews Pub Date : 2024-08-02 DOI: 10.1186/s13643-024-02619-9
Connor Forbes, Hannah Greenwood, Matt Carter, Justin Clark
{"title":"Automation of duplicate record detection for systematic reviews: Deduplicator.","authors":"Connor Forbes, Hannah Greenwood, Matt Carter, Justin Clark","doi":"10.1186/s13643-024-02619-9","DOIUrl":"10.1186/s13643-024-02619-9","url":null,"abstract":"<p><strong>Background: </strong>To describe the algorithm and investigate the efficacy of a novel systematic review automation tool \"the Deduplicator\" to remove duplicate records from a multi-database systematic review search.</p><p><strong>Methods: </strong>We constructed and tested the efficacy of the Deduplicator tool by using 10 previous Cochrane systematic review search results to compare the Deduplicator's 'balanced' algorithm to a semi-manual EndNote method. Two researchers each performed deduplication on the 10 libraries of search results. For five of those libraries, one researcher used the Deduplicator, while the other performed semi-manual deduplication with EndNote. They then switched methods for the remaining five libraries. In addition to this analysis, comparison between the three different Deduplicator algorithms ('balanced', 'focused' and 'relaxed') was performed on two datasets of previously deduplicated search results.</p><p><strong>Results: </strong>Before deduplication, the mean library size for the 10 systematic reviews was 1962 records. When using the Deduplicator, the mean time to deduplicate was 5 min per 1000 records compared to 15 min with EndNote. The mean error rate with Deduplicator was 1.8 errors per 1000 records in comparison to 3.1 with EndNote. Evaluation of the different Deduplicator algorithms found that the 'balanced' algorithm had the highest mean F1 score of 0.9647. The 'focused' algorithm had the highest mean accuracy of 0.9798 and the highest recall of 0.9757. The 'relaxed' algorithm had the highest mean precision of 0.9896.</p><p><strong>Conclusions: </strong>This demonstrates that using the Deduplicator for duplicate record detection reduces the time taken to deduplicate, while maintaining or improving accuracy compared to using a semi-manual EndNote method. However, further research should be performed comparing more deduplication methods to establish relative performance of the Deduplicator against other deduplication methods.</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"206"},"PeriodicalIF":6.3,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11295717/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141879501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of pharmacological treatments for severe agitation in real-world emergency settings: protocol of individual-participant-data network meta-analysis. 真实世界急救环境中严重躁动的药物治疗效果:个人参与者数据网络荟萃分析协议。
IF 6.3 4区 医学
Systematic Reviews Pub Date : 2024-08-02 DOI: 10.1186/s13643-024-02623-z
Spyridon Siafis, Hui Wu, Nobuyuki Nomura, Johannes Schneider-Thoma, Irene Bighelli, Carolin Lorenz, Joseph E Dib, Prathap Tharyan, Leonie A Calver, Geoffrey K Isbister, Esther W Y Chan, Jonathan C Knott, Celene Y L Yap, Célia Mantovani, Marc L Martel, David Barbic, William G Honer, Wulf-Peter Hansen, Gisele Huf, Jacob Alexander, Nirmal S Raveendran, Evandro S F Coutinho, Josef Priller, Clive E Adams, Georgia Salanti, Stefan Leucht
{"title":"Effectiveness of pharmacological treatments for severe agitation in real-world emergency settings: protocol of individual-participant-data network meta-analysis.","authors":"Spyridon Siafis, Hui Wu, Nobuyuki Nomura, Johannes Schneider-Thoma, Irene Bighelli, Carolin Lorenz, Joseph E Dib, Prathap Tharyan, Leonie A Calver, Geoffrey K Isbister, Esther W Y Chan, Jonathan C Knott, Celene Y L Yap, Célia Mantovani, Marc L Martel, David Barbic, William G Honer, Wulf-Peter Hansen, Gisele Huf, Jacob Alexander, Nirmal S Raveendran, Evandro S F Coutinho, Josef Priller, Clive E Adams, Georgia Salanti, Stefan Leucht","doi":"10.1186/s13643-024-02623-z","DOIUrl":"10.1186/s13643-024-02623-z","url":null,"abstract":"<p><strong>Background: </strong>Severe psychomotor agitation and aggression often require immediate pharmacological intervention, but clear evidence-based recommendations for choosing among the multiple options are lacking. To address this gap, we plan a systematic review and individual-participant-data network meta-analysis to investigate their comparative effectiveness in real-world emergency settings with increased precision.</p><p><strong>Methods: </strong>We will include randomized controlled trials investigating intramuscular or intravenous pharmacological interventions, as monotherapy or in combination, in adults with severe psychomotor agitation irrespective of the underlying diagnosis and requiring rapid tranquilization in general or psychiatric emergency settings. We will exclude studies before 2002, those focusing on specific reasons for agitation and placebo-controlled trials to avoid concerns related to the transitivity assumption and potential selection biases. We will search for eligible studies in BIOSIS, CENTRAL, CINAHL Plus, Embase, LILACS, MEDLINE via Ovid, PubMed, ProQuest, PsycINFO, ClinicalTrials.gov, and WHO-ICTRP. Individual-participant data will be requested from the study authors and harmonized into a uniform format, and aggregated data will also be extracted from the studies. At least two independent reviewers will conduct the study selection, data extraction, risk-of-bias assessment using RoB 2, and applicability evaluation using the RITES tool. The primary outcome will be the number of patients achieving adequate sedation within 30 min after treatment, with secondary outcomes including the need for additional interventions and adverse events, using odds ratios as the effect size. If enough individual-participant data will be collected, we will synthesize them in a network meta-regression model within a Bayesian framework, incorporating study- and participant-level characteristics to explore potential sources of heterogeneity. In cases where individual-participant data are unavailable, potential data availability bias will be explored, and models allowing for the inclusion of studies reporting only aggregated data will be considered. We will assess the confidence in the evidence using the Confidence in Network Meta-Analysis (CINeMA) approach.</p><p><strong>Discussion: </strong>This individual-participant-data network meta-analysis aims to provide a fine-tuned synthesis of the evidence on the comparative effectiveness of pharmacological interventions for severe psychomotor agitation in real-world emergency settings. The findings from this study can greatly be provided clearer evidence-based guidance on the most effective treatments.</p><p><strong>Systematic review registration: </strong>PROSPERO CRD42023402365.</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"205"},"PeriodicalIF":6.3,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11295517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141879502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The netball injury evidence base: a scoping review of methodologies and recommendations for future approaches. 净网球伤害证据基础:方法范围审查和未来方法建议。
IF 6.3 4区 医学
Systematic Reviews Pub Date : 2024-08-01 DOI: 10.1186/s13643-024-02629-7
Sara Horne, Aliah Faisal Shaheen, Bill Baltzopoulos, Laura Hills
{"title":"The netball injury evidence base: a scoping review of methodologies and recommendations for future approaches.","authors":"Sara Horne, Aliah Faisal Shaheen, Bill Baltzopoulos, Laura Hills","doi":"10.1186/s13643-024-02629-7","DOIUrl":"10.1186/s13643-024-02629-7","url":null,"abstract":"<p><strong>Background: </strong>Netball is a sport with a large participation base and a high risk of injuries. Effective injury prevention strategies are dependent upon a clear understanding of injury issues, aetiology and mechanisms, requiring robust research methodologies to ensure a reliable evidence base. This scoping review aims to identify the characteristics and range of netball injury research methodologies, to inform recommendations for future research.</p><p><strong>Methods: </strong>A systematic search of SPORTDiscus, MEDLINE, CINAHL and Academic Search Complete, PubMed, Scopus and Web of Science, from 1985 to May 2023 identified relevant studies. Inclusion criteria included peer-reviewed studies assessing injury incidence, aetiology and mechanisms in netball.</p><p><strong>Results: </strong>Following screening, 65 studies were included (68% descriptive epidemiology, 32% analytic epidemiology). Descriptive epidemiology reported data from hospital/clinic and insurance databases (57%) and netball competitions (43%). Only two studies used ongoing, systematic injury surveillance in netball cohorts, and significant heterogeneity existed in study designs, data collection methods, injury definitions and injury incidence rates calculations. Studies assessed a limited number of risk factors (descriptive competition studies: median: n = 4; analytic studies median: n = 6), with 76% using a simplistic reductionist approach to determine causality. Basic descriptions and retrospective recall of injury mechanisms reduced accuracy. Only two studies conducted comprehensive assessments of injury mechanisms using video-based methods.</p><p><strong>Conclusion: </strong>To establish an accurate netball injury evidence base, future research should prioritise the development of reliable, continuous surveillance systems. The International Olympic Committee (IOC) consensus statement guidelines are recommended for accurate injury data collection and reporting. A multifactorial approach should be adopted to assess the complex interaction between multiple risk factors, player load and the injury inciting event. Comprehensive descriptions of injury mechanisms using video methods, alongside descriptions from medical staff are recommended. This information is crucial for developing targeted prevention strategies.</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"203"},"PeriodicalIF":6.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11295446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141875960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of anesthesia on the success rate of external cephalic version: GRADE- assessed systematic review and meta-analysis of randomized controlled trials. 麻醉对头外翻转术成功率的影响:对随机对照试验进行GRADE评估的系统回顾和荟萃分析。
IF 6.3 4区 医学
Systematic Reviews Pub Date : 2024-07-30 DOI: 10.1186/s13643-024-02616-y
Liming Lei, Zhiyong Fang, Chenyang Xu, Zhaohui Wang, Hui Li, Li Ma
{"title":"Effect of anesthesia on the success rate of external cephalic version: GRADE- assessed systematic review and meta-analysis of randomized controlled trials.","authors":"Liming Lei, Zhiyong Fang, Chenyang Xu, Zhaohui Wang, Hui Li, Li Ma","doi":"10.1186/s13643-024-02616-y","DOIUrl":"10.1186/s13643-024-02616-y","url":null,"abstract":"<p><strong>Background: </strong>External cephalic version (ECV) is a medical procedure in which an extracorporeal manipulation is performed to render the breech presentation (BP) fetus in the cephalic position. The use of anesthesia to facilitate repositioning has been evaluated in various randomized clinical trials (RCTs), but its potential effectiveness remains controversial.</p><p><strong>Methods: </strong>A systematic literature search was carried out in 8 electronic databases. In the meta-analysis, a random effects model was used to calculate the pooled relative risk (RR) and its 95% confidence interval (CI), and the pooled standardized mean difference (SMD) and its 95% CI, in order to systematically assess the effect of anesthesia on the success rates of ECV, vaginal delivery, cesarean delivery as well as other outcomes. Relevant subgroup analyses, publication bias test and sensitivity analyses were also conducted.</p><p><strong>Results: </strong>This review included 17 RCTs. Women who received anesthesia had a significantly higher incidence of successful ECV (RR: 1.37, 95% CIs: 1.19-1.58) and vaginal delivery (RR: 1.23, 95% CIs: 1.03-1.47), and a significantly lower incidence of cesarean delivery (RR: 0.69, 95% CIs: 0.53-0.91), compared with those who did not.</p><p><strong>Conclusion: </strong>The administration of anesthesia not only significantly reduces maternal pain but also significantly increases the success rate of ECV in women with malpresentation at term, leading to a significant rise in the incidence of vaginal delivery. However, it may increase the incidence of maternal hypotension.</p><p><strong>Systematic review registration: </strong>The protocol was prospectively registered with PROSPERO, registration CRD42022381552.</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"202"},"PeriodicalIF":6.3,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11290114/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141856602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of remote ischemic conditioning on mortality after kidney transplantation: the systematic review and meta-analysis of randomized controlled trials. 远程缺血调理对肾移植术后死亡率的影响:随机对照试验的系统回顾和荟萃分析。
IF 6.3 4区 医学
Systematic Reviews Pub Date : 2024-07-29 DOI: 10.1186/s13643-024-02618-w
Eunji Ko, Ha Yeon Park, Choon Hak Lim, Hyun Jung Kim, Yookyung Jang, Hyunyoung Seong, Yun Hee Kim, Hyeon Ju Shin
{"title":"The effect of remote ischemic conditioning on mortality after kidney transplantation: the systematic review and meta-analysis of randomized controlled trials.","authors":"Eunji Ko, Ha Yeon Park, Choon Hak Lim, Hyun Jung Kim, Yookyung Jang, Hyunyoung Seong, Yun Hee Kim, Hyeon Ju Shin","doi":"10.1186/s13643-024-02618-w","DOIUrl":"10.1186/s13643-024-02618-w","url":null,"abstract":"<p><strong>Background: </strong>Ischemic-reperfusion injury resulting from kidney transplantation declines the post-transplant graft function. Remote ischemic conditioning (RIC) is known to be able to reduce the criticality of ischemic reperfusion injury. This study aimed to meta-analyze whether the application of remote ischemic conditioning to kidney transplantation patients improves clinical outcomes.</p><p><strong>Methods: </strong>Researchers included randomized controlled studies of the application of RIC to either kidney donors or recipients. Articles were retrieved from PubMed, Embase, Web of Science, and Cochrane Library. The risk of bias was evaluated using RoB 2.0. The primary outcome was mortality after transplantation. Secondary outcomes were the incidence of delayed graft function, graft rejection, and post-transplant laboratory results. All outcomes were integrated by RevMan 5.4.1.</p><p><strong>Results: </strong>Out of 90 papers, 10 articles (8 studies, 1977 patients) were suitable for inclusion criteria. Mortality collected at all time points did not show a significant difference between the groups. Three-month mortality (RR, 3.11; 95% CI, 0.13-75.51, P = 0.49) tended to increase in the RIC group, but 12-month (RR, 0.70; 95% CI, 0.14-3.45, P = 0.67) or final-reported mortality (RR, 0.49; 95% CI, 0.23-1.06, P = 0.07) was higher in the sham group than the RIC group. There was no significant difference between the RIC and sham group in delayed graft function (RR, 0.64; 95% CI, 0.30-1.35, P = 0.24), graft rejection (RR, 1.13; 95% CI, 0.73-1.73, P = 0.59), and the rate of time required for a 50% reduction in baseline serum creatinine concentration of less than 24 h (RR, 0.98; 95% CI, 0.61-1.56, P = 0.93).</p><p><strong>Conclusions: </strong>It could not be concluded that the application of RIC is beneficial to kidney transplantation patients. However, it is noteworthy that long-term mortality tended to decrease in the RIC group. Since there were many limitations due to the small number of included articles, researchers hope that large-scale randomized controlled trials will be included in the future.</p><p><strong>Systematic review registration: </strong>PROSPERO CRD42022336565.</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"201"},"PeriodicalIF":6.3,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11285121/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of mobile health interventions on service users’ health outcomes and the role of health professions: a systematic review of systematic reviews—protocol 移动医疗干预对服务使用者健康结果的影响以及医疗专业的作用:系统性审查的系统性审查--协议
IF 3.7 4区 医学
Systematic Reviews Pub Date : 2024-07-27 DOI: 10.1186/s13643-024-02624-y
Fathiya Alkhuzaimi, Deborah Rainey, Christine Brown Wilson, Jacqueline Bloomfield
{"title":"The impact of mobile health interventions on service users’ health outcomes and the role of health professions: a systematic review of systematic reviews—protocol","authors":"Fathiya Alkhuzaimi, Deborah Rainey, Christine Brown Wilson, Jacqueline Bloomfield","doi":"10.1186/s13643-024-02624-y","DOIUrl":"https://doi.org/10.1186/s13643-024-02624-y","url":null,"abstract":"Mobile health tools have gained prominence in global health care in recent years. Mobile health (mHealth) interventions have demonstrated their impact on managing healthcare service users’ health. A pilot search revealed many systematic reviews on the effectiveness of mobile health tools on service users’ health outcomes. However, how the role of healthcare professionals in promoting the adoption of mobile health may lead to improved outcomes needs to be clarified. Therefore, this systematic review aims to synthesise existing systematic reviews that examine both the impact of mobile health interventions on service users’ outcomes and the role of healthcare professionals in facilitating the adoption of mobile health solutions. Five electronic databases will be searched: EMBASE, CINHAL Plus, MEDLINE, Web of Science, and the Cochrane Library for systematic reviews exploring the impact of mobile health interventions on service users’ outcomes and the role of healthcare professionals in facilitating the adoption of mobile health solutions. Systematic reviews published in English dated from January 2015 to June 2024 will be included. Screening and selection of the reviews against inclusion and exclusion criteria will be performed by three independent reviewers, as well as data extraction and quality assessment. Current systematic reviews in mHealth have primarily focused on assessing the effectiveness of mHealth interventions for managing a range of conditions. While these reviews provide valuable input into the outcomes for mHealth, more is needed to know about the impact of the involvement of health professions on service users’ outcomes when adopting mHealth. This systematic review of systematic reviews aims to bridge this critical gap in the literature by critically appraising and synthesising the evidence of mHealth interventions’ impact on service user outcomes and the level of involvement of health professionals. PROSPERO CRD 42023414435.","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"53 10 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141770424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conceptualisation of health among young people: a protocol for systematic review and thematic synthesis of qualitative studies 年轻人的健康概念化:定性研究的系统审查和专题综合规程
IF 3.7 4区 医学
Systematic Reviews Pub Date : 2024-07-27 DOI: 10.1186/s13643-024-02614-0
Katrin Metsis, Joanna Inchley, Andrew James Williams, Sebastian Vrahimis, Lamorna Brown, Frank Sullivan
{"title":"Conceptualisation of health among young people: a protocol for systematic review and thematic synthesis of qualitative studies","authors":"Katrin Metsis, Joanna Inchley, Andrew James Williams, Sebastian Vrahimis, Lamorna Brown, Frank Sullivan","doi":"10.1186/s13643-024-02614-0","DOIUrl":"https://doi.org/10.1186/s13643-024-02614-0","url":null,"abstract":"Self-reported health is a widely used health indicator in surveys and questionnaires. The measure gained attention when research identified its association with mortality in the 1970s and 1980s. The measure is also associated with morbidity and other health outcomes such as the utilisation of health services. Self-reported health is a particularly useful measure for young people because this age group is generally clinically healthy. However, it is known that many chronic conditions have long latency periods that are initiated early in life. Because of its predictive nature, self-reported health can be used to estimate young people’s current and future health. Despite its widespread use, however, self-reported health remains a poorly understood concept. This paper presents the protocol for a systematic review that will identify and synthesise qualitative studies that investigate the factors that are considered by young people when they assess their health, and when they talk about health overall. The population of the review is young people aged 10–24 years, with or without health conditions. We will search the databases of MEDLINE (Ovid®), PsycINFO (APA PsycNet), ProQuest Sociology Collection, and Web of Science Core Collection™. We will also utilise techniques of reference checking and forward citation searching, as this strategy has been shown to result in a higher number of high-quality studies in social science systematic reviews. Google Scholar and Google Search were used during preliminary searches; Google Scholar will be utilised for forward citation searching. We will include studies written in English, German, or Finnish; there will be no lower date limit. One reviewer will screen all citations. A second reviewer will independently screen a sample of 20% of the abstracts. Data will be extracted by one researcher, two other researchers will independently review all data extracted, and quality appraisal will be completed by the first reviewer. We will utilise the Quality Framework for the appraisal of included articles and thematic synthesis of qualitative studies. The results of this systematic review will improve the understanding of the factors that are considered during the self-assessments of health; this will improve the interpretation of the results of quantitative research. Also, an improved understanding of the conceptualisation of health will inform the development of health policies and interventions that support young people’s health. PROSPERO CRD42022367519.","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"4 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141770421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Future support on evidence-informed priority setting and situational analysis of the potential role of Health Technology Assessment in Africa to support future pandemic preparedness and response: protocol for a scoping review. 未来支持以证据为依据确定优先事项,并对非洲卫生技术评估在支持未来大流行病防备和应对方面的潜在作用进行形势分析:范围界定审查协议。
IF 6.3 4区 医学
Systematic Reviews Pub Date : 2024-07-26 DOI: 10.1186/s13643-024-02610-4
Benjamin S C Uzochukwu, Chinyere Okeke, Francis Ruiz, Sergio Torres-Rueda, Joseph Kazibwe, Adaora Uzochukwu, Anna Vassall
{"title":"Future support on evidence-informed priority setting and situational analysis of the potential role of Health Technology Assessment in Africa to support future pandemic preparedness and response: protocol for a scoping review.","authors":"Benjamin S C Uzochukwu, Chinyere Okeke, Francis Ruiz, Sergio Torres-Rueda, Joseph Kazibwe, Adaora Uzochukwu, Anna Vassall","doi":"10.1186/s13643-024-02610-4","DOIUrl":"10.1186/s13643-024-02610-4","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 pandemic has highlighted the importance of evidence-informed priority setting and situational analysis in pandemic preparedness and response. Health Technology Assessment (HTA) has been identified as an essential tool for evidence-informed decision-making in healthcare. However, the potential role of HTA in pandemic preparedness and response in Africa has yet to be explored. The objective of this scoping review is to ascertain the current understanding of the possible role of HTA in Africa to support future pandemic preparedness and response.</p><p><strong>Methods: </strong>We will conduct a scoping review of literature published between 2010 and 2024. Electronic databases like Embase, PubMed, Scopus, Web of Science, and Google Scholar will be utilized to perform the search. We will also search grey literature sources such as websites of relevant organizations and government agencies. The search will only include studies that were conducted in the English language. Two reviewers will evaluate the titles and abstracts of the publications independently to determine their eligibility using Covidence. Full-text articles will be reviewed for eligibility and data extraction. The data will be extracted using a standardized form. The extracted data will include information on the study design, objectives, methods, findings, and conclusions. The thematic analysis approach will guide the data analysis. Themes and sub-themes will be identified and reported. The review will be reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) guidelines.</p><p><strong>Discussion: </strong>This scoping review will identify the existing knowledge on the potential role of HTA in Africa to support future pandemic preparedness and response. The findings will aid in identifying deficiencies in knowledge and provide valuable insights for future study. Additionally, they will inform policy-makers and other stakeholders about the potential contribution of the Health Technology Assessment (HTA) in enhancing Africa's readiness and response to pandemics.</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"198"},"PeriodicalIF":6.3,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11282749/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141767510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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