Biotechnology and Bioprocessing最新文献

{"title":"COVID-19 Pandemic, Disparity and Vaccine: An Update","authors":"Prabir Mandal","doi":"10.31579/2766-2314/020","DOIUrl":"https://doi.org/10.31579/2766-2314/020","url":null,"abstract":"Coronaviruses are a diverse group of viruses infecting many different animals, and they can cause mild to severe respiratory infections in humans. In 2002 and 2012, respectively, two highly pathogenic coronaviruses with zoonotic origin, severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV), emerged in humans and caused fatal respiratory illness, making emerging coronaviruses a new public health concern in the twenty-first century1. In early December 2019, an outbreak of coronavirus disease 2019 (COVID-19), caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), occurred in Wuhan City, Hubei Province, China. On January 30, 2020 the World Health Organization declared the outbreak as a Public Health Emergency of International Concern. As of February 14, 2020, 49,053 laboratory-confirmed and 1,381 deaths have been reported globally.","PeriodicalId":220919,"journal":{"name":"Biotechnology and Bioprocessing","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133091645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Individuals' Expectations Once Coronavirus Vaccine Successful and Available in Saudi Society","authors":"S. Sabra","doi":"10.31579/2766-2314/016","DOIUrl":"https://doi.org/10.31579/2766-2314/016","url":null,"abstract":"This paper was for \"Individuals' Expectations Once Coronavirus Vaccine (CVV) Successful and Available in Saudi Society (SS)\". The aim was for review community member's opinion importance during the Coronavirus pandemic (CVP), obtaining Coronavirus infection (CVI) protection, thereby reducing CVI, protection, and maintaining the public health (PH) in SS, that used as survey by questionnaire in SS. The results showed all participating < 20*yr were 40% and > 20yr were 60%, the women were 50% equal to men 50% participating. The participants 85.5% stated about the difficulty of the CVP period. It was 83.5% of the participants agreed prefer a CVV if it is available. That cleared 38.5% agreed on the presence of the CVV for protection a period of six months only. That was 72.5% they want and prefer for the protection of the CVV be for a period of one year. So appeared 52.5% agreed to buy the vaccine from his own money. It was 85.5% of the participants confirmed to protect family members by using the CVV if it is available; also 85.5% strongly affirm that individual members of SS must take the CVV, if it is available. That presented 47.5% of the participants confirmed the use of the CVV if it is available and even if it had side effects. That concluded CVV presence important for individuals to CVI protect and affect life in SS. Recommended the CVV important to protect against CVI and must be dealt with when its quality and use in SS and worldwide.","PeriodicalId":220919,"journal":{"name":"Biotechnology and Bioprocessing","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130093744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Applying Preventive Health Conditions Strategy during Coronavirus Pandemic in KSA","authors":"S. Sabra","doi":"10.31579/2766-2314/014","DOIUrl":"https://doi.org/10.31579/2766-2314/014","url":null,"abstract":"This research was for \"Influence of Applying Preventive Health Conditions Strategy (PHCS) during Coronavirus Pandemic (CVP) in Kingdom of Saudi Arabia (KSA)\". The target was through questionnaire to individuals in KSA. That application of PHCS and persons contribution accountable establishments, to cover Coronavirus infection (CVI), caused CVP and control to redact it, numbers to maintain Saudi health (SH). Using \"Cross-sectional Study Method\", were on Network for survey study in Saudi community (SC), collected data and had analyzed. Remained 99% participants to questionnaire about everyone, remained 89% dedicated to smearing PHCS closely a total. It was 100% reinforced PHCS, that 98% had approving support non-compliance PHCS. As stayed 83% stationary numerous parties from their doings, and was 100% all individuals, braked family visits in anticipation of any CVI. That stared 85% immobile market exit except for about individuals since it was a need to achieve family responsibilities, and others dedicated at home to decrease CVI. Experiential 74% produced the PHCS to have injury in three quarters because of discontinuing the numerous doings. Here 26% originated that a quarter of persons had cases of CVI, where 55% the relations applied the PHCS about partial because of the attendance of people with the similar family. That concluded the results showed the existence of the PHCS importance in the existence and importance of the CVP. The extent to KSA individuals helped to reduce CVI and protect SH. That recommended PHCS position to SH reserve, deliver a fit culture, and reinforce persons for their help.","PeriodicalId":220919,"journal":{"name":"Biotechnology and Bioprocessing","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125973843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Studies on Biotechnological Roles of Pleurotus spp","authors":"P. Chaurasia","doi":"10.31579/2766-2314/018","DOIUrl":"https://doi.org/10.31579/2766-2314/018","url":null,"abstract":"Pleurotus fungi are one of the biotechnologically treasured fungi may also be known as oyster or tree mushrooms. Pleurotus ostreatus is a widely used oyster mushroom. Edible mushrooms of this category are generally known for their significant roles in the various field of biotechnology like in food industries, bioremediation, enzyme production, medicinal biotechnology, bioengineering and so on. They have various biotechnologically valuable applications as promising bioremediation, anti-diabetic, anti-inflammatory, anti-cancerous, anti-microbial, anti-oxidant, and nematocidal and many more. This short review describes about the recent studies (year 2020) on the biotechnological applications of Pleurotus spp.","PeriodicalId":220919,"journal":{"name":"Biotechnology and Bioprocessing","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127940847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lysosomal or brush border enzymuria in kidney enzyme activities in seronegative rheumatoid arthritis","authors":"D. Spasovski","doi":"10.31579/2766-2314/019","DOIUrl":"https://doi.org/10.31579/2766-2314/019","url":null,"abstract":"Introduction: To determine the effects of non-treated seronegative rheumatoid arthritis (RA) on proximal renal tubule, sensitivity of Alanine aminopeptidase (AAP), g-glutamyltransferase (g--GT), β2 microglobulin in urine β2M), as well as relation with rheumatoid factor (RF) and C-Reactive protein (CRP), DAS 28 disease activity index. Methods: RF was determined by agglutination test (Latex RF test, while kinetic methods were used for determination of Alanine aminopeptidase (AAP) and g-glutamyltransferase (g-GT), as well as MEIA (Micro particle Enzyme Immunoassay) to determine β2 microglobulin in urine. Samples (serum and urine) of 70 participants were examined (35 RA not treated, 35 health control group). Results: In 35 RF negative RA, AAP enzymuria was present in 12 (34.28%) patients, g-GT was present in 7 patients (20%), while β2 microglobulin was present in 3 patients (8.57%). In the healthy control group, 4 patients showed AAP positivity (11.42%), 2 patients g-GT positivity (5.71%) and 1 patient showed presence of β2 microglobulin in urine (2.85). RF was not present in any patient (0%). Conclusion: AAP has a higher sensitivity of g-GT and b2 microglobulin in the detection of asymptomatic renal lesions in non treated seronegative RA.","PeriodicalId":220919,"journal":{"name":"Biotechnology and Bioprocessing","volume":"110 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120980721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revisiting the paper on “Applications of graph theory to enzyme kinetics and protein folding kinetics: steady and non-steady state systems”","authors":"K. Chou","doi":"10.31579/2766-2314/012","DOIUrl":"https://doi.org/10.31579/2766-2314/012","url":null,"abstract":"About 30 years ago a very important paper on “Applications of graph theory to enzyme kinetics and protein folding kinetics: steady and non-steady state systems”","PeriodicalId":220919,"journal":{"name":"Biotechnology and Bioprocessing","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130078056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ameliorating Effect of Green Tea Aqueous Extract against Histo pathophysiological Changes Induced by Ciprofibrate in the liver of Male Albino Rats","authors":"A. Azab","doi":"10.31579/2766-2314/013","DOIUrl":"https://doi.org/10.31579/2766-2314/013","url":null,"abstract":"Background: The liver is a specific target for drug toxicity because of its role in removal and metabolism of chemicals by converting drugs into another forms that can be readily removed from the body. It is known that the main function of the liver is the elimination of toxins that may enter the body, thus becoming vulnerable damaged during this mechanism, which can be revealed as bleeding, congestion, necrosis or other conditions of liver injury. Ciprofibrate belongs to widely used class of lipid-regulating agents, which stimulate hepatic cells and the hepatic cell becomes uncontrollably divided, causing liver growth. It causes liver cell proliferation in addition to other pleiotropic effects such as peroxisome proliferation and induction of certain peroxisomal and cytosolic enzymes in liver. Objective: The present study aimed to evaluate the potential beneficial effects of green tea aqueous extract administration against the biochemical and histological alterations induced in the liver by ciprofibrate in male rats. Materials and Methods: In the current study 3 groups of 6 male rats were used (Control group, 100mgKg body weight, and Cipro 100mgKg body weight with green tea). The rats have been treated daily orally by gavages for 21 days. On the last day of the experiment the animals were killed then blood samples and parts from the liver were collected. Liver function was examined for the serum Alanine Aminotransferase (ALT), Aspartate Aminotransferase (AST), alkaline phosphates (ALP), enzyme activities, and serum total & direct bilirubin concentrations. The histopathological investigation was conducted for the liver tissues of all groups. Results: Treatment of male rats with 100 mgKg body weight of ciprofibrate caused a significant increase in serum ALT, AST, and ALP activities, total, and direct bilirubin concentration. Histologically, there were histological changes in central vein area and portal zones, revealed congestion in blood sinusoids, necrosis in hepatic cells, and damage in central vein lining epithelium. Co-administration of green tea aqueous extract with Ciprofibrate significantly improved the structural changes in the liver and the serum ALT, AST, and ALP activities, total, and direct bilirubin concentrations were significantly declined. Conclusion: It can be concluded that Ciprofibrate treatment induced elevation in liver function tests and severe histopathological changes and green tea aqueous extract was able to protect the liver against these effects in male rats. So, the patients should be advised to take green tea aqueous extract while they are treated by ciprofibrate.","PeriodicalId":220919,"journal":{"name":"Biotechnology and Bioprocessing","volume":"54 17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127442391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Specific epithet – a noun in the genitive case","authors":"I. Ilieva","doi":"10.31579/2766-2314/009","DOIUrl":"https://doi.org/10.31579/2766-2314/009","url":null,"abstract":"The current article is included in the larger research “The linguistic structure of binomial botanical denominations– specific epithet”, based on “Conspectus of the Bulgarian vascular flora”, fourth revised and updated edition, Sofia, 2012, and deals with a less common type of specific epithets - nouns in the genitive case. The epithets are organized alphabetically in several groups according to their semantic.","PeriodicalId":220919,"journal":{"name":"Biotechnology and Bioprocessing","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121435402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The CO2 level as a factor stimulating angiogenesis Phenomena of tissue regeneration and destruction","authors":"M. Pawlikowski","doi":"10.31579/2766-2314/008","DOIUrl":"https://doi.org/10.31579/2766-2314/008","url":null,"abstract":"The regeneration of vessels and their development occur in places of their destruction. This phenomenon suggests that the destruction process itself stimulates vascular development and entails tissue healing and self-repair. Understanding the phenomena of self-repair is extremely important in the process of restoring tissues and organs to the proper functioning of individual organs and the entire body. Therefore, the recognition of angiogenesis processes seems to be the key in the treatment of many diseases.","PeriodicalId":220919,"journal":{"name":"Biotechnology and Bioprocessing","volume":"152 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114639846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analytical Methods for Determination of Salbutamol, Ambroxol and Fexofenadine","authors":"Mahmoud M. Sebaiy","doi":"10.31579/2766-2314/004","DOIUrl":"https://doi.org/10.31579/2766-2314/004","url":null,"abstract":"In this review article, we will introduce all reported methods that have been developed for determination of certain anti-tussive and anti-histaminic drugs such as salbutamol, ambroxol and fexofenadine in their pure form, combined form with other drugs, combined form with degradation products, and in biological samples. We also will shed the light on the most important combination of drugs that are used for treatment of asthma and related diseases.","PeriodicalId":220919,"journal":{"name":"Biotechnology and Bioprocessing","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133209096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}