Spinal Cord Series and Cases最新文献_第7页

The relationship between balance control and thigh muscle strength and muscle activity in persons with incomplete spinal cord injury. 不完全脊髓损伤患者的平衡控制与大腿肌肉力量和肌肉活动之间的关系。

IF 1.2

Spinal Cord Series and Cases Pub Date : 2024-02-28 DOI: 10.1038/s41394-024-00620-x

Matthijs Ferdinand Wouda, Marte Fosvold Løtveit, Espen Ingvald Bengtson, Vegard Strøm

{"title":"The relationship between balance control and thigh muscle strength and muscle activity in persons with incomplete spinal cord injury.","authors":"Matthijs Ferdinand Wouda, Marte Fosvold Løtveit, Espen Ingvald Bengtson, Vegard Strøm","doi":"10.1038/s41394-024-00620-x","DOIUrl":"10.1038/s41394-024-00620-x","url":null,"abstract":"Study design: Cross-sectional study.Objectives: A spinal cord injury (SCI) can compromise the ability to maintain sufficient balance control during activities in an upraised position. The objective of the study was to explore the relationship between balance control and muscle strength and muscle activation in the lower extremities in persons with incomplete SCI (iSCI).Setting: Sunnaas Rehabilitation Hospital, Norway.Methods: Thirteen men and two women with iSCI and 15 healthy, matched controls were included. Performance of the Berg Balance Scale (BBS) short version (7 items) was used to indicate balance control. Maximal voluntary contraction (MVC) was performed to measure isometric muscle strength in thigh muscles (knee extension/flexion), while surface electromyography (EMG) was measured from M. Vastus Lateralis and M. Biceps Femoris. The relative activation of each muscle during each of the BBS tasks was reported as the percentage of the maximal activation during the MVC (%EMGmax).Results: The iSCI participants had a significantly lower BBS sum score and up to 40% lower muscle strength in knee- flexion and extension compared to the matched healthy controls. They also exhibited a significantly higher %EMGmax, i.e. a higher muscle activation, during most of the balance tests. Univariate regression analysis revealed a significant association between balance control and mean values of %EMGmax in Biceps Femoris, averaged over the seven BBS tests.Conclusions: The participants with iSCI had poorer balance control, reduced thigh muscle strength and a higher relative muscle activation in their thigh muscles, during balance-demanding activities.","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":"10 1","pages":"7"},"PeriodicalIF":1.2,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10902359/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139991239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intramedullary spinal cord abscess involving Actinomyces and Streptococcus: a case report and literature review. 涉及放线菌和链球菌的脊髓髓内脓肿：病例报告和文献综述。

IF 1.2

Spinal Cord Series and Cases Pub Date : 2024-02-17 DOI: 10.1038/s41394-024-00618-5

Shunsuke Nakamura, Hiroya Shimauchi-Ohtaki, Fumiaki Honda, Yutaka Tokue, Yuhei Yoshimoto

{"title":"Intramedullary spinal cord abscess involving Actinomyces and Streptococcus: a case report and literature review.","authors":"Shunsuke Nakamura, Hiroya Shimauchi-Ohtaki, Fumiaki Honda, Yutaka Tokue, Yuhei Yoshimoto","doi":"10.1038/s41394-024-00618-5","DOIUrl":"10.1038/s41394-024-00618-5","url":null,"abstract":"Introduction: Intramedullary spinal cord abscesses (ISCA) are rare and caused by central nervous system infections. Although polymicrobial infections are rarely seen in ISCAs, isolation of the causative pathogen is important for treatment. Here, we describe a very rare case of ISCA resulting from a mixed Streptococcus and Actinomyces infection.Case presentation: An 82-year-old man presented with acute posterior cervical pain and progressive quadriplegia. Radiological investigations revealed a mass lesion showing marginal enhancement at the level of the C3-4 vertebrae. Microsurgical drainage was performed, and Streptococcus and Actinomyces were identified as causative agents. Subsequent antibiotic treatment was noted to be beneficial to the patient.Discussion: This case suggests that mixed infection can develop into ISCA depending on the causative agents such as Actinomyces. Prompt pathogen-directed antibacterial therapy is required for ISCA treatment.","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":"10 1","pages":"6"},"PeriodicalIF":1.2,"publicationDate":"2024-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10874371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139898270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 and spinal cord injury: clinical presentation, clinical course, and clinical outcomes of people hospitalised. COVID-19 与脊髓损伤：住院患者的临床表现、临床过程和临床结果。

IF 1.2

Spinal Cord Series and Cases Pub Date : 2024-02-13 DOI: 10.1038/s41394-024-00617-6

Inge E Eriks-Hoogland, Michael A Barth, Lorena L Müller, Dominique Braun, Armin Curt, Mohit Arora, James W Middleton, Jürgen Pannek

{"title":"COVID-19 and spinal cord injury: clinical presentation, clinical course, and clinical outcomes of people hospitalised.","authors":"Inge E Eriks-Hoogland, Michael A Barth, Lorena L Müller, Dominique Braun, Armin Curt, Mohit Arora, James W Middleton, Jürgen Pannek","doi":"10.1038/s41394-024-00617-6","DOIUrl":"10.1038/s41394-024-00617-6","url":null,"abstract":"Study design: Retrospective study OBJECTIVES: To describe the presenting symptoms/signs, clinical course and outcomes in hospitalised people with spinal cord injury (SCI) and symptomatic COVID-19 infections.Setting: One university hospital and two SCI centres in Switzerland.Methods: Descriptive analysis of symptoms/signs, clinical course and outcomes of people with SCI with symptomatic COVID-19 infections and need for hospitalisation.Results: Twenty-two people with SCI were included, 15 (68%) were male, median age 64.5 years (interquartile range, IQR, 52-73 years). Nine (41%) had tetraplegia, and eight (36%) were classified with motor-complete lesions. Frequent clinical symptoms were fever (59%), coughing (54%), fatigue (50%), and dyspnoea (27%). Most frequent complications were bacterial pulmonary superinfection (18%), and acute respiratory distress syndrome (18%). Fifteen persons (68%) needed oxygen therapy during the course of hospitalisation, and 7 (32%) people were ventilated. Median length of stay (LOS) was 23 days (IQR 15-35), varying by age for people under 60 years with a median LOS of 9 days (IQR 8-27), and for those older than 60 years with a median of 34 days (IQR 17-39), respectively. In total, 3 persons (14%) died during hospitalisation, all older with paraplegia.Conclusions: Typical symptoms like fever and coughing were not present in all people. People with tetraplegia did not demonstrate worse outcomes, on the contrary, they had shorter LOS, no difference in ventilation needs, and no higher mortality compared to people with paraplegia. Older people showed longer LOS. This study recommends close supervision of the SCI population to detect early signs and symptoms of COVID-19 infection.","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":"10 1","pages":"5"},"PeriodicalIF":1.2,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10864293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139730576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The critical role of magnetic resonance imaging in the diagnosis of transverse myelitis: a case report. 磁共振成像在横贯性脊髓炎诊断中的关键作用：病例报告。

IF 1.2

Spinal Cord Series and Cases Pub Date : 2024-02-10 DOI: 10.1038/s41394-024-00616-7

Esther Omotola Adewuyi, Zainab Adedamola Abdulsalam, Olorunnisola Onaolapo Olatide

{"title":"The critical role of magnetic resonance imaging in the diagnosis of transverse myelitis: a case report.","authors":"Esther Omotola Adewuyi, Zainab Adedamola Abdulsalam, Olorunnisola Onaolapo Olatide","doi":"10.1038/s41394-024-00616-7","DOIUrl":"10.1038/s41394-024-00616-7","url":null,"abstract":"Introduction: Transverse Myelitis is a rare inflammatory disorder of the spinal cord, characterized by the inflammation of the myelin sheath covering nerve fibers. Although rare, Transverse Myelitis holds significant clinical importance due to its potential life-altering consequences. The case report provides insight into the clinical presentation of Transverse Myelitis and the importance of Magnetic Resonance Imaging in confirming Transverse Myelitis.Case presentation: A 27-year-old Nigerian female presented to a hospital facility after 2 months onset of paraplegia, urinary, and fecal incontinence. She was diagnosed with Acute Transverse Myelitis with Magnetic Resonance Imaging, a lacking imaging modality in Nigeria. On presentation, it was important to rule out spinal cord compression, a close differential to her presentation. Despite her late arrival at the facility, early diagnosis and prompt initiation of treatment with high-dose intravenous steroids and physiotherapy improved her quality of life.Discussion: This case report reveals the poor health-seeking behavior in developing countries and the need for imaging modalities like Magnetic Resonance Imaging for improved diagnoses of rare neurological conditions such as Transverse Myelitis. The lack of healthcare infrastructure has led to clinical misdiagnosis, patient mismanagement, and underrepresentation of data in the country, underscoring the critical role of diagnostic tools for improved patient care pre-treatment and post-treatment. Additionally, follow-up of these patients is important to prevent the long-term sequelae of Transverse Myelitis like Neuromyelitis Optica or Multiple Sclerosis.","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":"10 1","pages":"4"},"PeriodicalIF":1.2,"publicationDate":"2024-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10858937/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139716428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identifying prescribers of antibiotics in a primary care spinal cord injury cohort 在初级保健脊髓损伤队列中识别抗生素处方者

IF 1.2

Spinal Cord Series and Cases Pub Date : 2024-02-01 DOI: 10.1038/s41394-024-00615-8

Arrani Senthinathan, Melanie Penner, Karen Tu, Andrew M. Morris, B. Catharine Craven, Susan B. Jaglal

{"title":"Identifying prescribers of antibiotics in a primary care spinal cord injury cohort","authors":"Arrani Senthinathan, Melanie Penner, Karen Tu, Andrew M. Morris, B. Catharine Craven, Susan B. Jaglal","doi":"10.1038/s41394-024-00615-8","DOIUrl":"https://doi.org/10.1038/s41394-024-00615-8","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Study design</h3>A retrospective cross-sectional study.<h3 data-test=\"abstract-sub-heading\">Objective</h3>To identify who prescribes outpatient antibiotics among a primary care spinal cord injury (SCI) cohort.<h3 data-test=\"abstract-sub-heading\">Setting</h3>ICES databases in Ontario, Canada.<h3 data-test=\"abstract-sub-heading\">Methods</h3>A cohort of individuals with SCI were retrospectively identified using a tested-algorithm and chart reviews in a primary care electronic medical records database. The cohort was linked to a drug dispensing database to obtain outpatient antibiotic prescribing information, and prescriber details were obtained from a physician database.<h3 data-test=\"abstract-sub-heading\">Results</h3>Final cohort included three hundred and twenty individuals with SCI. The average annual number of antibiotic courses dispensed for the SCI cohort was 2.0 ± 6.2. For dispensed antibiotics, 58.9% were prescribed by rostered-primary care practice physicians, compared to 17.9% by emergency and non-rostered primary care physicians, 17.4% by specialists and 6.1% by non-physician prescribers. Those who lived in urban areas and rural areas, compared to those who lived in suburban areas, were more likely to receive antibiotics from emergency and non-rostered primary care physicians than from rostered-primary care practice physicians.<h3 data-test=\"abstract-sub-heading\">Conclusion</h3>Although individuals with SCI received outpatient antibiotic prescriptions from multiple sources, physicians from an individual’s rostered-primary care practice were the main antibiotic prescribers. As such, interventions to optimize antibiotics use in the SCI population should target the primary care practice.","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":"284 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139669423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sleeve gastrectomy as a bridge to maternity in a patient with obesity, infertility and tetraplegia. A case report 袖带胃切除术是肥胖、不孕和四肢瘫痪患者生育的桥梁。病例报告

IF 1.2

Spinal Cord Series and Cases Pub Date : 2024-01-20 DOI: 10.1038/s41394-024-00614-9

Franco Alejandro Corvatta, Virginia Margarita Cano Busnelli, Axel Federico Beskow, Susana Gutt, Fernando Gabriel Wright

{"title":"Sleeve gastrectomy as a bridge to maternity in a patient with obesity, infertility and tetraplegia. A case report","authors":"Franco Alejandro Corvatta, Virginia Margarita Cano Busnelli, Axel Federico Beskow, Susana Gutt, Fernando Gabriel Wright","doi":"10.1038/s41394-024-00614-9","DOIUrl":"https://doi.org/10.1038/s41394-024-00614-9","url":null,"abstract":"Traumatic spinal cord injury (SCI) is a major cause of severe and permanent disability in young adults. Overweight and obesity are commonly observed among patients affected with SCI, with reports of a prevalence of over 60 and 30% respectively. Case report: A 34 year-old woman suffering from tetraplegia after sustaining a traumatic injury to C5-C6 at age 23 as a result of a motor vehicle accident was presented to our hospital’s multidisciplinary bariatric team due to class II obesity. At the time of presentation to the team, eleven years after the accident, her BMI was calculated to be 39 Kg/m2 (weight 97 kg, height 1.57 meters). She was diagnosed with infertility while seeking pregnancy, and referred to our bariatric unit for weight loss. In addition, she had overcome the physical limitations of her injury, had a regular job and was engaged in regular physical activities such as swimming. In May 2017, she underwent laparoscopic sleeve gastrectomy (LSG) without complications and was discharged on postoperative day 2. 17 months following LSG, with a normal BMI, she became naturally pregnant. She had emergency cesarean at 35 weeks due to pneumonia but both patient and child recovered without sequelae. Currently, 4 years after surgery she maintains 37.11% total weight loss (weight 61 kg). She reports having a better quality of life with fewer medical intercurrencies. Conclusions: Patients with SCI and obesity, particularly women seeking to conceive, may be benefited by being referred to bariatric teams for assessment and treatment to improve results associated with sustained weight reduction.","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":"2 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139508689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Technical note: Traumatic atlanto-occipital dislocation and severe subaxial cervical distraction injury in an infant 技术说明：一名婴儿的外伤性寰枕脱位和严重的颈椎轴下牵拉伤

IF 1.2

Spinal Cord Series and Cases Pub Date : 2024-01-04 DOI: 10.1038/s41394-023-00612-3

Alexander M. Tucker, Peter J. Madsen, Shih-Shan Lang, Phillip B. Storm

{"title":"Technical note: Traumatic atlanto-occipital dislocation and severe subaxial cervical distraction injury in an infant","authors":"Alexander M. Tucker, Peter J. Madsen, Shih-Shan Lang, Phillip B. Storm","doi":"10.1038/s41394-023-00612-3","DOIUrl":"https://doi.org/10.1038/s41394-023-00612-3","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Introduction</h3>Traumatic injuries of the spine requiring surgery are rare in infancy. Fusion procedures in the very young are not well-described at the atlanto-occipital junction or subaxial spine. Here we describe novel segmental posterior instrumentation in a severe spinal column disruption in an infant.<h3 data-test=\"abstract-sub-heading\">Case presentation</h3>A 13-month-old male with atlanto-occipital dislocation and severe C6-7 distraction (ASIA impairment scale A) presented after a motor vehicle accident. He underwent instrumented fusion (occiput-C2 and C6-7) and halo placement. Postoperative imaging demonstrated reduction of the C6-7 vertebral bodies. Physical examination showed lower limb paraplegia and preserved upper extremity strength except for mild weakness in hand grip (3/5 on the MRC grading scale). Occiput-C2 instrumentation was performed using occipital keel and C2 pedicle screws with sublaminar C1 polyester tape. C6-7 reduction and fixation was performed with laminar hooks. Arthrodesis was promoted with lineage-committed cellular bone matrix allograft and suboccipital autograft. Anterior column stabilization was deferred secondary to a CSF leak. Intraoperative monitoring was performed throughout the procedure. Within 1 month after surgery the patient was able to manipulate objects against gravity. CT imaging revealed bony fusion and spontaneous reduction of C6-7.<h3 data-test=\"abstract-sub-heading\">Discussion</h3>Spinal instrumentation is technically challenging in infants, regardless of injury mechanism, particularly in cases with complete spinal column disruption, but an anterior fusion may be avoided in infants and small children with posterior stabilization and halo placement.","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":"2 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139093590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of postprandial hypotension with acarbose in an adult with cervical spinal cord injury: a case report 用阿卡波糖治疗一名颈脊髓损伤成人的餐后低血压：病例报告

IF 1.2

Spinal Cord Series and Cases Pub Date : 2023-12-18 DOI: 10.1038/s41394-023-00613-2

Sabrina S. Dieffenbach, Hannah Aura Shoval

{"title":"Treatment of postprandial hypotension with acarbose in an adult with cervical spinal cord injury: a case report","authors":"Sabrina S. Dieffenbach, Hannah Aura Shoval","doi":"10.1038/s41394-023-00613-2","DOIUrl":"https://doi.org/10.1038/s41394-023-00613-2","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Introduction</h3>Postprandial hypotension is a type of autonomic dysfunction where there is a decrease in systolic blood pressure of >20 mm HG within 2 h after eating thought to be due to poor cardiovascular compensation for splanchnic blood pooling that occurs with meals. This form of autonomic dysfunction is underdiagnosed in patients with spinal cord injury, likely in part because it can be asymptomatic.<h3 data-test=\"abstract-sub-heading\">Case presentation</h3>26-year-old with complete cervical spinal cord injury (SCI) presented with neck pain described as severe 10/10 pain, which felt like “a rope around his neck.” Pain came on during and after meals and was associated with a feeling of pressure behind his eyes, white spots in his vision along with feeling as if he was going to pass out. The caregiver noted a systolic blood pressure drop by about 30–40 points with meals and lost weight due to avoiding eating. A diagnosis of post-prandial hypotension (PPH) was made and Acarbose was started at a low dose 25 mg three times per day with meals. During follow up, the patient reported complete resolution of drops of blood pressure, neck pain, and all associated symptoms. The patient was able to eat comfortably and gained weight.<h3 data-test=\"abstract-sub-heading\">Discussion</h3>There are few case reports on PPH in SCI and none looking at acarbose on a young, nondiabetic person with SCI. Clinicians should be aware that PPH can occur in young otherwise healthy people with SCI. Further research is needed on PPH, including the use of acarbose, in the SCI population.","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":"106 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138715871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The presence of Candida parapsilosis with intrathecal baclofen pump in a person with high cervical spinal cord injury; infection or colonization? A Case Report. 高颈脊髓损伤患者鞘内巴氯芬泵伴假丝酵母旁裂症的存在感染还是殖民?一个病例报告。

IF 1.2

Spinal Cord Series and Cases Pub Date : 2023-11-30 DOI: 10.1038/s41394-023-00610-5

John Chan, Harminder Singh, Kazuko Shem

{"title":"The presence of Candida parapsilosis with intrathecal baclofen pump in a person with high cervical spinal cord injury; infection or colonization? A Case Report.","authors":"John Chan, Harminder Singh, Kazuko Shem","doi":"10.1038/s41394-023-00610-5","DOIUrl":"10.1038/s41394-023-00610-5","url":null,"abstract":"Introduction: Intrathecal baclofen (ITB) therapy is an effective method of treating spasticity in persons with spasticity due to spinal cord injury (SCI), but complications are not rare and can include spinal fluid leaks, infection, and catheter/pump malfunction.Case presentation: This study presents information related to an adult male patient with traumatic SCI and a history of two prior ITB pump pocket infections that required removal due to pump infection. The patient then developed skin erosion over the third pump, and the fluid around the pump grew methicillin-sensitive Staphylococcus aureus, diphtheroids, and Candida parapsilosis. The patient was initially treated with antibiotics and anti-fungal medication without removal of the ITB pump. The ITB pump was eventually removed 27 months later, and the fourth pump was implanted 10 months later.Discussion: ITB pumps can be an effective treatment modality for spasticity in people with SCI; however, complications, including infection, can occur and require pump removal. This case illustrates a case of possible Candida colonization of the ITB pump, which was eventually removed.","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":"9 1","pages":"55"},"PeriodicalIF":1.2,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689785/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138462749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Organophosphorus poisoning induced delayed neurotoxicity: a report of two cases. 有机磷中毒引起的迟发性神经毒性：附2例报告。

IF 0.7

Spinal Cord Series and Cases Pub Date : 2023-11-04 DOI: 10.1038/s41394-023-00611-4

Amrutha Viswanath, Apurba Barman, Jagannatha Sahoo, Souvik Bhattacharjee, Suman Patel

{"title":"Organophosphorus poisoning induced delayed neurotoxicity: a report of two cases.","authors":"Amrutha Viswanath, Apurba Barman, Jagannatha Sahoo, Souvik Bhattacharjee, Suman Patel","doi":"10.1038/s41394-023-00611-4","DOIUrl":"10.1038/s41394-023-00611-4","url":null,"abstract":"Introduction: Organophosphorus compounds (OPC) are one of the most commonly used pesticides worldwide and are often misused for suicidal poisoning due to their easy availability. Acute manifestations and management of organophosphorus (OP) poisoning have been reported several times. Organophosphorus-induced delayed neurotoxicity (OPIDN) is a rare delayed presentation of OP poisoning that involves central-peripheral distal axonopathy.Case presentation: In this study, we report two cases of OPIDN developed after a few weeks of OP poisoning. Clinical features, electrodiagnostic study findings, and rehabilitative measures adopted for the patients and their follow-up have been described in the report.Discussion: Organophosphorus (OP) poisoning may rarely produce features of delayed neurotoxicity, which may gradually appear after acute cholinergic symptoms. This report shows the importance of considering the delayed presentation of possible OPC toxicity in patients with neurological symptoms and a history of OPC exposure.","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":"9 1","pages":"54"},"PeriodicalIF":0.7,"publicationDate":"2023-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71486269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0