Sports Medicine最新文献

{"title":"Sport-Specific Impact Loading is Associated with Bone Mineral Density in Athletes: Implications for Relative Energy Deficiency in Sport (REDs) Assessment.","authors":"Trent Stellingwerff, Ming-Chang Tsai, Walter T P McCluskey, Louise M Burke, Matthew D Fliss, Kathryn E Ackerman, Ida A Heikura","doi":"10.1007/s40279-026-02478-5","DOIUrl":"10.1007/s40279-026-02478-5","url":null,"abstract":"<p><strong>Background: </strong>Both sport-specific impact loading and Relative Energy Deficiency in Sport (REDs) are known to impact bone mineral density and bone stress injuries in athletes; however, the interactive effects are still emerging.</p><p><strong>Objective: </strong>The primary aim was to investigate the effects of sport-specific impact loading on bone mineral density and bone stress injuries and the influence this has on the International Olympic Committee's REDs Clinical Assessment Tool-Version 2 severity/risk assessment.</p><p><strong>Methods: </strong>Female (n = 143) and male (n = 70) athletes (performance tier 3-5) from 13 different sports were cross-sectionally assessed with the Clinical Assessment Tool-Version 2 (questionnaire, blood, dual-energy X-ray absorptiometry-derived bone mineral density assessment), and prospectively assessed for new bone stress injuries, and compared across low-, medium-, and high-impact loading sports.</p><p><strong>Results: </strong>Spine and femoral neck Z-scores were significantly lower in low- and medium-impact versus high-impact sports (p < 0.01). The highest femoral neck Z-scores were in the high-impact group, with nearly all other low- and medium-impact groups being significantly (p < 0.016) lower regardless of REDs traffic-light status. The adjusted odds of future bone stress injuries were approximately three-fold higher in athletes with a recent bone stress injury (previous 2 years only; p = 0.16). Athletes in low-, medium- and high-impact sports with zero to low-risk REDs (green + yellow traffic-light) had femoral neck Z-scores of 0.4 ± 0.9, 0.5 ± 0.9 and 1.4 ± 1.0, respectively (p < 0.01).</p><p><strong>Conclusions: </strong>Sport-specific impact loading significantly influences bone mineral density independent of REDs risk/severity status. These findings indicate that practitioners should interpret bone mineral density results in the context of an athlete's specific sport background rather than relying solely on general population norms, enabling more accurate REDs risk assessment and targeted injury-prevention strategies.</p>","PeriodicalId":21969,"journal":{"name":"Sports Medicine","volume":" ","pages":"2893-2907"},"PeriodicalIF":11.0,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148253433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of Intermittent Hypoxic Training Strategies on Maximal Oxygen Uptake in Healthy Humans: A Meta-analysis with Meta-regression.","authors":"Dario Kohlbrenner, Abdallah Ghaith, Joey Fournier, Charles Khouri, Antonin Bordas, Samarmar Chacaroun, Monique Mendelson, Patrice Flore, Mathieu Marillier, Julien Brugniaux, Jean-Louis Pépin, Renaud Tamisier, Samuel Verges","doi":"10.1007/s40279-026-02482-9","DOIUrl":"10.1007/s40279-026-02482-9","url":null,"abstract":"<p><strong>Background: </strong>Intermittent hypoxic training aims to enhance exercise performance and health, commonly assessed through maximal oxygen uptake (VO₂max). Currently applied methods are live-high train-low (LHTL), live-low train-high (LLTH) and passive hypoxic conditioning (PHC). However, within these methods, numerous modes of application exist, and effectiveness is debated.</p><p><strong>Objective: </strong>To determine the effect of LHTL, LLTH and PHC on VO₂max in healthy participants, and identify factors associated with the amplitude of change in VO₂max.</p><p><strong>Methods: </strong>We conducted a systematic review with random-effects meta-analysis and meta-regression. Studies were identified through PubMed, EMBASE and Web of Science. We included controlled studies, calculating between-group standardised mean differences. Athlete and non-athlete populations were analysed separately. RoB2 was used to assess study quality and publication bias was investigated with funnel plots and the Egger's test.</p><p><strong>Results: </strong>Of the 5244 identified studies, 62 were included for analysis, resulting in a sample size of 1332 participants (610 athletes, 722 non-athletes). LHTL increased VO₂max significantly more than control in athletes (mean difference [MD] = 2.17; 95% CI = 0.77, 3.56) but not in non-athletes (MD = 3.1; 95% CI =  - 0.23, 6.43). LLTH did not increase VO₂max significantly more than control in athletes (MD = 0.89; 95% CI =  - 0.27, 2.05) but it did in non-athletes (MD = 1.70; 95% CI = 0.85, 2.54). PHC did not increase VO₂max significantly more than control in athletes (MD =  - 1.07; 95% CI =  - 3.51, 1.37) but it did in non-athletes (MD = 2.26; 95% CI = 1.00, 3.52). Multivariate meta-regressions identified the severity, duration, and frequency of hypoxic exposure to be significantly associated with the change in VO₂max.</p><p><strong>Conclusions: </strong>LHTL showed a significant effect on VO₂max in athletic populations while LLTH and PHC showed a significant effect on VO₂max in non-athletic populations only. Future studies should target investigating which characteristics (e.g. severity, duration) of the hypoxic exposure are most beneficial.</p>","PeriodicalId":21969,"journal":{"name":"Sports Medicine","volume":" ","pages":"2767-2782"},"PeriodicalIF":11.0,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13672411/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148977882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Comment on \"Developing a Fundamental Theoretical Definition for Athletic Injury: Metaphysics, Logic, and Mathematics\".","authors":"Judd T Kalkhoven","doi":"10.1007/s40279-026-02505-5","DOIUrl":"10.1007/s40279-026-02505-5","url":null,"abstract":"","PeriodicalId":21969,"journal":{"name":"Sports Medicine","volume":" ","pages":"2917-2919"},"PeriodicalIF":11.0,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148685904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Systematic Review with Meta-analysis of the Association between Changes in Muscle Strength and Clinical Outcome Changes in Patellofemoral Pain.","authors":"Guilherme S Nunes, Matheus Weide Solner, Jênifer de Oliveira, Bruna Wageck, Anna Julia Meireles Dangui","doi":"10.1007/s40279-026-02473-w","DOIUrl":"10.1007/s40279-026-02473-w","url":null,"abstract":"<p><strong>Objective: </strong>To investigate whether muscle strength changes observed in randomised controlled trials involving people with patellofemoral pain (PFP) are associated with concurrent changes in pain and physical function.</p><p><strong>Design: </strong>Systematic review with meta-analysis, applying a two-stage structural equation modelling approach with random-effects estimation.</p><p><strong>Eligibility criteria: </strong>Randomised clinical trials assessing non-surgical and non-pharmacological interventions that reported both muscle strength and at least one clinical outcome (pain or function) in people with PFP.</p><p><strong>Data sources: </strong>CINAHL, Cochrane Library, Embase, Medline and SPORTDiscus were searched from inception to April 2026.</p><p><strong>Results: </strong>From 16,750 records screened, 82 trials met the eligibility criteria (4023 participants). Regarding self-reported pain outcomes, low to moderate evidence certainty indicated significant associations between strength improvements and pain reduction for knee extensors (r =  - 0.75, β =  - 0.21), knee flexors (r =  - 0.46, β =  - 0.14), hip abductors (r =  - 0.91, β =  - 0.31), hip adductors (r =  - 0.26, β =  - 0.19), hip external rotators (r =  - 0.24, β =  - 0.06), hip internal rotators (r =  - 0.79, β =  - 0.31) and hip extensors (r =  - 0.58, β =  - 0.26). Regarding self-reported function, low to high evidence certainty indicated that strength improvements in knee extensors (r = 0.70, β = 0.15), knee flexors (r = 0.46, β = 0.07), hip abductors (r = 0.94, β = 0.15), hip adductors (r = 0.55, β = 0.11), and hip internal rotators (r = 0.98, β = 0.06) were significantly associated with improved function.</p><p><strong>Conclusions: </strong>This review provides evidence that improvements in lower limb muscle strength are associated with improvements in pain and physical function among people with PFP. These findings reinforce the clinical relevance of strength-focused rehabilitation, particularly targeting the knee and hip muscles.</p><p><strong>Registration number: </strong>CRD42023420875.</p>","PeriodicalId":21969,"journal":{"name":"Sports Medicine","volume":" ","pages":"2717-2731"},"PeriodicalIF":11.0,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13672437/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148259587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on: \"Developing a Fundamental Theoretical Definition for Athletic Injury: Metaphysics, Logic, and Mathematics\".","authors":"Anne Hecksteden, Oliver Faude, Lars Donath","doi":"10.1007/s40279-026-02504-6","DOIUrl":"10.1007/s40279-026-02504-6","url":null,"abstract":"","PeriodicalId":21969,"journal":{"name":"Sports Medicine","volume":" ","pages":"2913-2915"},"PeriodicalIF":11.0,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148679734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin B6 in Elite Athletes: Potential Implications of High Intakes.","authors":"Thomas Valente van Keulen, Nathan A Lewis, Charles R Pedlar","doi":"10.1007/s40279-026-02534-0","DOIUrl":"10.1007/s40279-026-02534-0","url":null,"abstract":"<p><p>Vitamin B6 plays a role in over 100 enzymatic reactions, and it is purported that athletes have higher requirements compared with the general population. Deficiency, while rare, may lead to adverse symptoms if severe or prolonged. Conversely, excessive intake may increase the risk of toxicity. This article discusses the potential implications of high vitamin B6 exposure in athletes and includes illustrative observational data on plasma pyridoxal 5'-phosphate (PLP) from routine biomarker monitoring in elite athletes. Observation-level deficiencies (< 30 nmol/L; 5.2%) and raised (> 125 nmol/L; 38.7%) PLP measurements (n = 654) in elite athletes (N = 396) participating in routine biomarker screening, alongside implications of possible intakes above athletes' requirements are discussed. Athletes' use of nutritional supplements, sports beverages, or even intravenous nutrition, which contain highly bioavailable doses of vitamin B6, are a plausible contributor to the observed high PLP concentrations. Chronic total vitamin B6 intake above 21 mg/day, particularly with low protein intake, may increase toxicity risk.</p>","PeriodicalId":21969,"journal":{"name":"Sports Medicine","volume":" ","pages":"2633-2639"},"PeriodicalIF":11.0,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148956557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary FODMAP Manipulation for Exercise-Associated Gastrointestinal Symptoms: Why Symptom Severity Should Guide Our Approach.","authors":"Rachel Scrivin, Natália Vilela Silva Daniel, Gary Slater, Ricardo J S Costa","doi":"10.1007/s40279-026-02474-9","DOIUrl":"10.1007/s40279-026-02474-9","url":null,"abstract":"<p><p>Exercise-induced gastrointestinal syndrome (EIGS) is a well-defined term that describes disruptions to gastrointestinal integrity and function that occur during exercise. A commonly reported outcome of EIGS is exercise-associated gastrointestinal symptoms (Ex-GIS), including flatulence, lower abdominal bloating and pain, and urge to defecate, which can compromise comfort, training quality and race-day execution. Low-fermentable oligo-, di-, mono-saccharide and polyol (FODMAP) diets are effective at reducing gastrointestinal symptoms in individuals with irritable bowel syndrome and, owing to similarities in symptom presentation, have increasingly been used by athletes to better manage Ex-GIS. This Current Opinion article argues that FODMAP manipulation should be used strategically rather than as a routine dietary default. For athletes with severe Ex-GIS, a short-term low-FODMAP approach may help attenuate symptoms around key training sessions and/or competition. In contrast, athletes with mild or infrequent symptoms may benefit from a more liberal FODMAP intake that mitigates disruptions to gastrointestinal integrity and potentially EIGS outcomes while avoiding unnecessary dietary restriction. However, neither approach has consistently been shown to improve performance. Accordingly, any modification of FODMAP intake should be individualized and guided by likely underlying primary mechanisms, symptom severity, exercise demands, and the need to maintain overall dietary adequacy.</p>","PeriodicalId":21969,"journal":{"name":"Sports Medicine","volume":" ","pages":"2641-2653"},"PeriodicalIF":11.0,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13672648/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148580151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reconceptualising Mental Fatigue via Perceptual Control: From Concept Label to Constitutive Definition.","authors":"Daniel F Gucciardi, Hugh Riddell, Stephen J Tidman, Kagan J Ducker, Warren Mansell","doi":"10.1007/s40279-026-02544-y","DOIUrl":"https://doi.org/10.1007/s40279-026-02544-y","url":null,"abstract":"<p><p>Mental fatigue is widely invoked to explain performance decrements across high-stakes domains. The prevailing definition calls mental fatigue \"a psychobiological state caused by prolonged demanding cognitive activity and characterised by subjective feelings of tiredness.\" This definition has two flaws. It confuses the label with the constitutive properties of the concept, and it treats the dissociations among self-report, performance and physiology as mixed measurement effects, when those dissociations are diagnostically informative. We argue this conflation reflects a definitional problem disguised as a measurement issue. Drawing on perceptual control theory, we reconceptualise mental fatigue as a transient state of an effort-regulation control system. In this state, the system's controlled perception-functional viability-persistently remains below its reference during sustained cognitive control. This state arises from, and is maintained by, resource-goal conflict-conflict between resource-management systems (signalling conservation needs) and goal-management systems (signalling task importance). Our constitutive definition does four things. It clarifies the entity (a specific regulator), specifies the property (persistent error reflecting unresolved resource-goal conflict) and articulates the intrinsic attribute (viability below reference). From these clarifications, it derives observable indicators along an economisation continuum-efficiency adjustments, reduced precision, elevated effort, disengagement-without collapsing the concept into any single indicator. Neighbouring constructs are distinguished by their conflict structure and economisation profile. The framework is offered as a falsifiable architecture that organises measurement, generates testable predictions, and accelerates the development of credible psychobiological markers and countermeasures.</p>","PeriodicalId":21969,"journal":{"name":"Sports Medicine","volume":" ","pages":""},"PeriodicalIF":11.0,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149220610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Exercise Training on the Metabolic Cost of Walking in Health and Disease: A Systematic Review and Meta-analysis.","authors":"Tibor Hortobágyi, Urs Granacher, Jennifer Brach, Davide Malatesta, Beáta Csizmadia, Bálint Kovács, Jingyi Ye, Mohamed Abdelaziz Emam, András Attila Horváth, Tomas Vetrovsky","doi":"10.1007/s40279-026-02553-x","DOIUrl":"https://doi.org/10.1007/s40279-026-02553-x","url":null,"abstract":"<p><strong>Background: </strong>The metabolic cost of walking (Cw) increases with heathy aging and in neurological conditions. No comprehensive assessment has been performed yet to determine whether chronic exercise training and rehabilitation could improve Cw.</p><p><strong>Objective: </strong>The purpose of this study was to determine whether the effects of chronic exercise interventions on Cw differ by type, dose, and intensity in healthy adults and individuals with neurological conditions (multiple sclerosis, Parkinson's disease, and stroke).</p><p><strong>Design: </strong>Systematic review and robust variance estimation meta-analysis with meta-regression following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.</p><p><strong>Data sources: </strong>Systematic search of Medline, Web of Science, and CINAHL databases.</p><p><strong>Results: </strong>A total of 27 studies with 36 intervention arms and 54 outcomes in 1177 participants, of those 703 healthy adults and 474 patients with multiple sclerosis (1 study), Parkinson's disease (1 study), and stroke (9 studies) were included. Across all types of training (aerobic, resistance, other), chronic physical exercise training improved Cw (g = 0.40, p = 0.001). Improvements were significant in healthy individuals (g = 0.49, p = 0.001) but not in patients with stroke (g = 0.24, p = 0.065). Meta-regression confirmed that population moderated the effects of training on Cw (p = 0.043) after adjusting for exercise training characteristics. In the adjusted meta-regression, higher study-level mean body mass index (BMI) was associated with smaller intervention effects on Cw (β = - 0.20, p = 0.040). Training type, duration, intensity, frequency, and session duration did not significantly moderate the training effects on Cw, although the meta-regression may have been underpowered to detect such associations. Heterogeneity (I² < 62.5%) and risk of bias were moderate.</p><p><strong>Conclusions: </strong>This is the first meta-synthesis examining the effects of diverse forms of exercise training on Cw in different populations. Chronic physical exercise training improves Cw in healthy adults, with smaller effects observed in individuals with stroke. The findings support chronic physical exercise training as an effective strategy for improving walking economy.</p>","PeriodicalId":21969,"journal":{"name":"Sports Medicine","volume":" ","pages":""},"PeriodicalIF":11.0,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Return to Competition and Career Sustainability After Primary ACL Reconstruction in Football: A Nationwide Cohort Study of Long-Term Participation.","authors":"Alexander Sandon, Christoffer von Essen, Abdulaziz Farooq, Magnus Forssblad","doi":"10.1007/s40279-026-02558-6","DOIUrl":"https://doi.org/10.1007/s40279-026-02558-6","url":null,"abstract":"<p><strong>Background: </strong>Return to competition (RTC) after anterior cruciate ligament reconstruction (ACLR) is frequently reported, but long-term football participation following return remains poorly described.</p><p><strong>Objective: </strong>The aim was to describe RTC rates after primary ACLR in football players and to evaluate post-RTC career sustainability, quantified by the number of matches and seasons played, across sex, age, and pre-injury level.</p><p><strong>Methods: </strong>In this decade-long nationwide cohort study, football players undergoing primary ACLR between 2014 and 2023 were identified in the Swedish Knee Ligament Registry and linked to the Swedish Football Association's match database. RTC was defined as participation in one or more official match after surgery. Analyses of post-RTC match and season participation were restricted to players who returned by the 2022 season or earlier, allowing a minimum potential follow-up of three seasons. Outcomes were compared across sex, age groups, and pre-injury level using non-parametric methods.</p><p><strong>Results: </strong>A total of 10,836 football players were included, of whom 6339 (58.5%) achieved RTC. RTC rates varied across pre-injury competitive levels, ranging from 90.4% at the top level to 35.9% at the recreational level (p < 0.001). Among players with sufficient follow-up (n = 4749), median post-RTC participation was 31 matches (interquartile range [IQR] 11-70) across three seasons (IQR 2-5). Men accumulated more matches after RTC than women (33 vs 29; p = 0.017) and remained active for more seasons (4 vs 3; p < 0.001). Pre-injury competitive level was strongly associated with career sustainability (p < 0.001): top-level players accumulated a median of 97 matches (IQR 42-148) across five seasons (IQR 3-6), whereas players competing at lower levels accumulated fewer matches and seasons. Age-related differences were significant in men but not in women.</p><p><strong>Conclusion: </strong>Football career sustainability following primary ACLR was greatest among players competing at higher pre-injury levels and, to a lesser extent, among men. Although RTC was commonly achieved, long-term participation after return was often limited, indicating that RTC alone provides an incomplete description of football participation after ACLR.</p>","PeriodicalId":21969,"journal":{"name":"Sports Medicine","volume":" ","pages":""},"PeriodicalIF":11.0,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}