Spine deformity最新文献

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Clinical and radiographic outcomes of 19 proximal thoracic pedicle subtraction osteotomies for adult spinal deformity: a case series. 19例胸椎近端椎弓根减截骨术治疗成人脊柱畸形的临床和影像学结果:一个病例系列。
IF 1.6
Spine deformity Pub Date : 2025-07-01 Epub Date: 2025-03-20 DOI: 10.1007/s43390-025-01076-1
Justin Bird, Maxwell M Scott, Christopher Lucasti, Benjamin C Graham, David Kowalski, Emily K Vallee, Danielle E Chipman, Dil V Patel, Christopher L Hamill
{"title":"Clinical and radiographic outcomes of 19 proximal thoracic pedicle subtraction osteotomies for adult spinal deformity: a case series.","authors":"Justin Bird, Maxwell M Scott, Christopher Lucasti, Benjamin C Graham, David Kowalski, Emily K Vallee, Danielle E Chipman, Dil V Patel, Christopher L Hamill","doi":"10.1007/s43390-025-01076-1","DOIUrl":"10.1007/s43390-025-01076-1","url":null,"abstract":"<p><strong>Purpose: </strong>To present a detailed analysis of postoperative clinical and radiographic outcomes of patients who underwent proximal thoracic pedicle subtraction osteotomy (PSO) for adult spinal deformity.</p><p><strong>Methods: </strong>A retrospective chart review was performed on 19 patients who underwent proximal thoracic (T2-T4) PSO between January 2018 and December 2021. Baseline patient characteristics, complications and radiographic outcomes were collected. Radiographic outcomes including thoracic kyphosis correction, overall segment correction, and global sagittal balance correction were measured using preoperative and postoperative radiographs.</p><p><strong>Results: </strong>19 patients with an average age of 66.9 ± 8.3 years underwent thoracic PSO, with 94.7% (n = 18) being females, in the setting of revision surgery. The mean thoracic kyphosis correction was 20.4 ± 8.5°. Overall segmental correction had a mean of 16.2 ± 3.9°. Global sagittal balance correction was an average of 13.9 ± 23.2 mm (mm). The median hospital stay was 4.0 (IQR: 3.0) days with a median of 1.0 (IQR: 2.0) days in the intensive care unit. 36.8% (n = 7) of patients had a major complication within 30 days: proximal junction kyphosis (PJK) (2), neurologic deficits (2), pneumonia (1), cardiopulmonary (1), death (1). 47.4% (n = 9) of patients had a major complication within 2 years: PJK (5), neurologic deficits (2), wound dehiscence/infection (1), pneumonia (1), cardiopulmonary (1), death (2). Average follow up was 636 (range: 43-1320).</p><p><strong>Conclusion: </strong>While thoracic PSO can achieve successful radiographic and clinical outcomes, it is also associated with a high risk of potential major complications and mortality, such as instrumentation or junctional failure and neurologic deficits.</p>","PeriodicalId":21796,"journal":{"name":"Spine deformity","volume":" ","pages":"1241-1251"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12227515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Left-sided thoracic curves in adolescent idiopathic scoliosis: are the outcomes different? 青少年特发性脊柱侧凸左胸弯曲:结局不同吗?
IF 1.6
Spine deformity Pub Date : 2025-07-01 Epub Date: 2025-04-02 DOI: 10.1007/s43390-025-01069-0
Bryan O Ren, Anne Marie Dumaine, Jerry Y Du, Daniel J Hedequist, Michael P Glotzbecker
{"title":"Left-sided thoracic curves in adolescent idiopathic scoliosis: are the outcomes different?","authors":"Bryan O Ren, Anne Marie Dumaine, Jerry Y Du, Daniel J Hedequist, Michael P Glotzbecker","doi":"10.1007/s43390-025-01069-0","DOIUrl":"10.1007/s43390-025-01069-0","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose was to compare outcomes in adolescent idiopathic scoliosis (AIS) patients with left vs. right main thoracic curves. A secondary purpose was to elucidate surgeon opinions between these two curve types and differences in surgical approach via a survey.</p><p><strong>Methods: </strong>A multicenter database was utilized to identify AIS patients with left thoracic curves without significant MRI abnormalities from 1996 to 2018 receiving posterior spinal fusion. A 1:1 propensity match was performed to right thoracic curves. Differences between the curve groups were analyzed.</p><p><strong>Results: </strong>Fifty patients had left thoracic curves. Curve direction had no impact on levels fused, surgical time, length of hospitalization, estimated blood loss, cell saver transfused, death, pain, pseudoarthrosis, reoperation, or infection rates. At two-years postoperatively, left curves had greater T2-T12 kyphosis (37 vs. 31°, p = .02), and variations in T1 tilt angle direction (30 vs. 39 left tilt, p = .04), EIV angulation (-2 vs. 5°, p < .01), EIV translation (0.6 vs. -0.2 cm, p = .03), and left shoulder elevation (12 in left curves vs. 25 in right curves, p = .01). There were no differences in correction rate, Cobb angle, lumbar curve, T12-S1 lordosis, shoulder height difference, or SRS 22 scores.</p><p><strong>Conclusion: </strong>In AIS, there are no significant differences in surgical characteristics or outcomes between left and right-thoracic curves. Notably, curve direction does not influence correction rate, surgical time, levels fused, length of hospitalization, blood loss, pain, SRS 22 scores, or rates of reoperation, infection, or pseudoarthrosis. There are some variations in radiographic parameters postoperatively that are unlikely to be clinically significant.</p>","PeriodicalId":21796,"journal":{"name":"Spine deformity","volume":" ","pages":"1067-1074"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12227501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143765023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developmental delay increases risk for complications within 30 days of pediatric spinal fusion surgery. 发育迟缓增加了小儿脊柱融合手术30天内并发症的风险。
IF 1.6
Spine deformity Pub Date : 2025-07-01 Epub Date: 2025-04-05 DOI: 10.1007/s43390-025-01081-4
Haseeb E Goheer, Zachary M Johnson, Alexander R Garcia, Brian Q Truong, Alden H Newcomb, Jonathan J Carmouche
{"title":"Developmental delay increases risk for complications within 30 days of pediatric spinal fusion surgery.","authors":"Haseeb E Goheer, Zachary M Johnson, Alexander R Garcia, Brian Q Truong, Alden H Newcomb, Jonathan J Carmouche","doi":"10.1007/s43390-025-01081-4","DOIUrl":"10.1007/s43390-025-01081-4","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to investigate whether developmental delay is a risk factor for postoperative complications following pediatric spinal fusion.</p><p><strong>Methods: </strong>The American College of Surgeons National Surgical Quality Improvement Program Pediatric database was queried to retrospectively identify patients who had undergone spinal fusions between 2016 and 2021. The study population was divided into two distinct groups 1) Patients with developmental delay 2) who have no delay. T-tests for continuous variables and chi-square tests for categorical variables were used to identify differences in perioperative characteristics between the two groups. Multivariable logistic regression analysis assessed the effect of preoperative developmental delay on post-operative surgical outcomes.</p><p><strong>Results: </strong>A total of 32,621 pediatric spinal fusion patients were identified, of which 7,637 had developmental delay and 24,984 had no delay. The developmental delay group had a higher rate of surgical complications and medical complications (5.38% vs 1.41%, p < 0.001). Developmental delay independently increased the risk for medical complications (OR: 1.099, 95% CI: (1.009-1.978), surgical complications (OR: 1.4833, 95% CI (1.197-1.838), extended hospital LOS (OR: 1.250, 95% CI (1.028-1.518), intensive care unit stay (OR: 1.333, 95% CI (1.227-1.446), and death (OR: 9.638, 95% CI: 2.150-68.700) following a multivariate logistic regression analysis.</p><p><strong>Conclusion: </strong>Patients with developmental delay undergoing pediatric spinal fusion had an increased risk for surgical complications. The findings of this study serve as a valuable resource in aiding surgeons in preoperative risk assessment and in facilitating comprehensive discussions with patients and their caregivers.</p>","PeriodicalId":21796,"journal":{"name":"Spine deformity","volume":" ","pages":"1033-1040"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12227350/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143788710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of a multi-disciplinary care pathway on intensive care unit and total hospital length of stay in high-risk neuromuscular scoliosis patients who require posterior spinal fusion: a quality improvement study. 多学科护理路径对需要后路脊柱融合术的高危神经肌肉性脊柱侧凸患者重症监护病房和总住院时间的影响:一项质量改善研究
IF 1.6
Spine deformity Pub Date : 2025-07-01 DOI: 10.1007/s43390-025-01112-0
Lorena V Floccari, Bryce Pember, Kenzie D Lundqvist, Matthew B Holloway, Richard P Steiner, Michael T Bigham, Kenneth T Bono, Todd F Ritzman
{"title":"The impact of a multi-disciplinary care pathway on intensive care unit and total hospital length of stay in high-risk neuromuscular scoliosis patients who require posterior spinal fusion: a quality improvement study.","authors":"Lorena V Floccari, Bryce Pember, Kenzie D Lundqvist, Matthew B Holloway, Richard P Steiner, Michael T Bigham, Kenneth T Bono, Todd F Ritzman","doi":"10.1007/s43390-025-01112-0","DOIUrl":"https://doi.org/10.1007/s43390-025-01112-0","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to establish a multi-disciplinary consensus-based standardized perioperative care pathway for high-risk neuromuscular scoliosis (NMS) patients requiring posterior spinal fusion (PSF) and to compare patient outcomes before and after its implementation.</p><p><strong>Methods: </strong>A retrospective comparative cohort study was performed at a freestanding children's hospital in the United States. A multi-disciplinary team reviewed published evidence and developed a consensus-based standardized perioperative pathway that was implemented in May 2018. Pre-pathway (1/2014-4/2018) NMS patients with complex multi-system involvement who underwent PSF were compared to post-pathway (5/2018-12/2023) patients in demographics, radiographic characteristics, surgical variables, disposition, length of stay (LOS), and complications.</p><p><strong>Results: </strong>Ninety-one patients were included (30 pre-pathway, 61 post-pathway). There were no significant differences in patient demographics or curve characteristics. Central venous catheters were used more often in the pre-pathway group (50.0% vs 27.9%, p = 0.039). The post-pathway group had longer mean fusion length (14.4 vs 15.3 levels, p = 0.015), greater frequency of pelvic instrumentation (43.3% vs 73.8%, p = 0.005), and a longer mean operative time (316 vs 357 min, p = 0.032). The post-pathway group had a significantly shorter median intensive care unit (ICU) LOS (2.5 vs 2.0 nights, p = 0.017) and a significantly shorter median hospital LOS (7.5 vs 5.0 days, p < 0.001). There were no statistically significant differences in early complications.</p><p><strong>Conclusion: </strong>After implementation of a comprehensive multi-disciplinary pathway for high-risk scoliosis patients, patients had a 20% shorter median ICU LOS and a 33% shorter median hospital LOS despite more complex surgeries. Both groups had a similar incidence of early postoperative complications.</p><p><strong>Level of evidence: </strong>Level III.</p>","PeriodicalId":21796,"journal":{"name":"Spine deformity","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144542163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to "ChatGPT to answer frequently asked questions on scoliosis: comment". 回复“ChatGPT回答脊柱侧凸常见问题:评论”。
IF 1.6
Spine deformity Pub Date : 2025-07-01 Epub Date: 2025-05-14 DOI: 10.1007/s43390-025-01109-9
Brigitte Lieu, Ethan Crawford, Logan Laubach, Teja Yeramosu, Chester Sharps, Joanna Horstmann, Victoria Kuester
{"title":"Response to \"ChatGPT to answer frequently asked questions on scoliosis: comment\".","authors":"Brigitte Lieu, Ethan Crawford, Logan Laubach, Teja Yeramosu, Chester Sharps, Joanna Horstmann, Victoria Kuester","doi":"10.1007/s43390-025-01109-9","DOIUrl":"10.1007/s43390-025-01109-9","url":null,"abstract":"","PeriodicalId":21796,"journal":{"name":"Spine deformity","volume":" ","pages":"1285-1286"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Construct-construct "rail technique" decreases screw strain during spinal deformity corrective maneuvers: a mechanical analysis. 构造-构造 "轨道技术 "可减少脊柱畸形矫正操作过程中的螺钉应变:机械分析。
IF 1.6
Spine deformity Pub Date : 2025-07-01 Epub Date: 2025-03-28 DOI: 10.1007/s43390-025-01079-y
Alekos A Theologis, Jason DePhillips, Nathaniel A Myers, Jonathan M Mahoney, Brandon S Bucklen
{"title":"Construct-construct \"rail technique\" decreases screw strain during spinal deformity corrective maneuvers: a mechanical analysis.","authors":"Alekos A Theologis, Jason DePhillips, Nathaniel A Myers, Jonathan M Mahoney, Brandon S Bucklen","doi":"10.1007/s43390-025-01079-y","DOIUrl":"10.1007/s43390-025-01079-y","url":null,"abstract":"<p><strong>Purpose: </strong>To compare screw strains adjacent to a simulated spinal osteotomy between segmental compression (SC) and cantilever bending (CB) to SC and CB performed over a construct-to-construct lateral accessory rod (\"rail\").</p><p><strong>Methods: </strong>10 PCF foam blocks were instrumented with 6 polyaxial pedicle screws, each with a linear strain gage. SC and CB were performed over a traditional construct (midline rods) or over a construct-to-construct lateral accessory rod. Real-time screw strains were collected and peak strains were reported and compared between corrective techniques.</p><p><strong>Results: </strong>Strains in screws closest to the osteotomy were significantly less during \"rail\" compression compared to traditional SC. Maximum screw strains were significantly lower during \"rail\" SC (p < .001) and CB (p = 0.003) compared to traditional SC and CB, respectively. Total screw strain was more evenly distributed over all 6 screws during \"rail\" compression and CB compared to traditional techniques, which concentrated strain at individual screws adjacent to the osteotomy.</p><p><strong>Conclusions: </strong>Performing SC and CB across an accessory construct-to-construct lateral (\"rail\") rod resulted in significantly lower strain on individual pedicle screws adjacent to a simulated spinal osteotomy compared to traditional SC and CB. As such, the \"rail\" may lessen risk of screw pull-out and screw plow during maneuvers to correct spinal deformities. Future work focused on building upon this controlled study in cadaveric specimens will be important to validate these findings in more clinically relevant scenarios.</p>","PeriodicalId":21796,"journal":{"name":"Spine deformity","volume":" ","pages":"987-995"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12227462/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143736214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of a classification system for potential sources of error in robotic-assisted spine surgery. 机器人辅助脊柱手术中潜在错误来源分类系统的开发。
IF 1.6
Spine deformity Pub Date : 2025-07-01 Epub Date: 2025-04-01 DOI: 10.1007/s43390-025-01066-3
Ritt R Givens, Terrence T Kim, Matan S Malka, Kevin Lu, Thomas M Zervos, Joseph Lombardi, Zeeshan Sardar, Ronald Lehman, Lawrence Lenke, Rajiv Sethi, Stephen Lewis, Daniel Hedequist, Themistocles Protopsaltis, A Noelle Larson, Sheeraz Qureshi, Brandon Carlson, David Skaggs, Michael G Vitale
{"title":"Development of a classification system for potential sources of error in robotic-assisted spine surgery.","authors":"Ritt R Givens, Terrence T Kim, Matan S Malka, Kevin Lu, Thomas M Zervos, Joseph Lombardi, Zeeshan Sardar, Ronald Lehman, Lawrence Lenke, Rajiv Sethi, Stephen Lewis, Daniel Hedequist, Themistocles Protopsaltis, A Noelle Larson, Sheeraz Qureshi, Brandon Carlson, David Skaggs, Michael G Vitale","doi":"10.1007/s43390-025-01066-3","DOIUrl":"10.1007/s43390-025-01066-3","url":null,"abstract":"<p><strong>Purpose: </strong>Robotic-assisted spine surgery (RASS) has increased in prevalence over recent years, and while much work has been done to analyze differences in outcomes when compared to the freehand technique, little has been done to characterize the potential pitfalls associated with using robotics. This study's goal was to leverage expert opinion to develop a classification system of potential sources of error that may be encountered when using robotics in spine surgery. This not only provides practitioners, particularly those in the early stages of robotic adoption, with insight into possible sources of error but also provides the community at large with a more standardized language through which to communicate.</p><p><strong>Methods: </strong>The Delphi method, which is a validated system of developing consensus, was utilized. The method employed an iterative presentation of classification categories that were then edited, removed, or elaborated upon during several rounds of discussion. Voting took place to accept or reject the individual classification categories with consensus defined as ≥ 80% agreement.</p><p><strong>Results: </strong>After a three-round iterative survey and video conference Delphi process, followed by an in-person meeting at the Safety in Spine Surgery Summit, consensus was achieved on a classification system that includes four key types of potential sources of error in RASS as well as a list of the most commonly identified sources within each category. Initial sources of error that were considered included: cannula skidding/skive, penetration, screw misplacement, registration failure, and frame shift. After completion of the Delphi process, the final classification included four major types of pitfalls including: Reference/Navigation, Patient Factors, Technique, and Equipment Factors (available at https://safetyinspinesurgery.com/ ).</p><p><strong>Conclusion: </strong>This work provides expert insight into potential sources of error in the setting of robotic spine surgery. The working group established four discrete categories while providing a standardized language to unify communication.</p>","PeriodicalId":21796,"journal":{"name":"Spine deformity","volume":" ","pages":"1231-1239"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trunk endurance differences between female adolescents with and without idiopathic scoliosis. 有和没有特发性脊柱侧凸的女性青少年躯干耐力的差异。
IF 1.6
Spine deformity Pub Date : 2025-07-01 Epub Date: 2025-03-21 DOI: 10.1007/s43390-025-01075-2
Hanh Thi Nguyen, Thanh-Van Le, Tan Minh Pham, Hieu Kim Huynh, Philippe Mahaudens, Ngoc-Minh Nguyen
{"title":"Trunk endurance differences between female adolescents with and without idiopathic scoliosis.","authors":"Hanh Thi Nguyen, Thanh-Van Le, Tan Minh Pham, Hieu Kim Huynh, Philippe Mahaudens, Ngoc-Minh Nguyen","doi":"10.1007/s43390-025-01075-2","DOIUrl":"10.1007/s43390-025-01075-2","url":null,"abstract":"<p><strong>Purpose: </strong>This study compared trunk muscle endurance between female adolescents with idiopathic scoliosis (AIS) and non-AIS groups.</p><p><strong>Methods: </strong>This cross-sectional study included 91 females. Trunk muscle endurance was assessed using the Ito-Shirado and Biering-Sørensen tests. Anthropometric and radiographic data were collected. The Mann-Whitney U test compared endurance and abdominal-to-paraspinal endurance ratio between groups. Spearman's correlation assessed relationships between endurance and participant characteristics.</p><p><strong>Results: </strong>The AIS group's performance on the Ito-Shirado and Biering-Sørensen tests was 57% and 68% of the non-AIS group's test durations, respectively (p = 0.001). However, there was no significant difference in the abdominal-to-paraspinal endurance ratio between the two groups (p = 0.7). Additionally, a low negative correlation was observed between paraspinal muscle endurance and both weight (rho = - 0.29, p = 0.006)) and BMI (rho = - 0.3, p = 0.005) in the AIS group, while abdominal endurance correlated negatively with height (rho = - 0.25, p = 001).</p><p><strong>Discussion: </strong>Females with AIS exhibit significantly reduced endurance in both paraspinal and abdominal muscles compared to healthy controls, despite maintaining a similar abdominal-to-paraspinal endurance ratio. The findings suggest the need for trunk muscle endurance evaluation and training in rehabilitation programs for individuals with AIS.</p>","PeriodicalId":21796,"journal":{"name":"Spine deformity","volume":" ","pages":"1059-1066"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimizing bone health for the prevention of revision adult spinal deformity surgery: a break-even analysis. 优化骨骼健康预防成人脊柱畸形翻修手术:盈亏平衡分析。
IF 1.6
Spine deformity Pub Date : 2025-07-01 Epub Date: 2025-04-11 DOI: 10.1007/s43390-025-01070-7
Andrew H Kim, William ElNemer, Marc Greenberg, Micheal Raad, Khaled M Kebaish
{"title":"Optimizing bone health for the prevention of revision adult spinal deformity surgery: a break-even analysis.","authors":"Andrew H Kim, William ElNemer, Marc Greenberg, Micheal Raad, Khaled M Kebaish","doi":"10.1007/s43390-025-01070-7","DOIUrl":"10.1007/s43390-025-01070-7","url":null,"abstract":"<p><strong>Purpose: </strong>To determine the viability of preoperative bone health optimization for the prevention of revision surgery due to osteoporosis among adult spinal deformity (ASD) patients using break-even economic modeling.</p><p><strong>Methods: </strong>The cost of a DXA scan and total 2-year cost of revision ASD surgery were obtained from institutional records. 2-Year ASD revision rates among patients with osteoporosis were obtained from the literature. An open-access database was used to determine the mean retail price for Teriparatide, Denosumab, and Zoledronic acid. Total optimization costs included the costs of a DXA scan and medication treatment. Costs were adjusted for inflation using the Consumer Price Index to 2023 U.S. dollars. A break-even economic analysis was performed to determine the absolute risk reduction (ARR) and number needed to treat (NNT) to economically justify each treatment.</p><p><strong>Results: </strong>DXA scan ($349.28) and revision ASD surgery ($147,731.78) costs were obtained from institutional records. The cost of optimizing patients with DXA and Teriparatide, Denosumab, and Zoledronic acid was $4,410.32, $3,832.78, and $1,552.61, respectively. Each treatment modality was cost-effective at all revision ASD surgery rates. Teriparatide was economically justified if the initial revision rate decreased by 2.99% (NNT = 34), Denosumab by 2.59% (NNT = 39), and Zoledronic acid by 1.05% (NNT = 96).</p><p><strong>Conclusion: </strong>Preoperative bone health optimization among ASD patients undergoing surgery is highly cost-effective in the prevention of revision surgery due to osteoporosis. Teriparatide would need to prevent 1 revision surgery out of 34 ASD surgeries, Denosumab 1 out of 39, and Zoledronic acid 1 out of 96 to break-even on costs.</p>","PeriodicalId":21796,"journal":{"name":"Spine deformity","volume":" ","pages":"1205-1212"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiographic and clinical findings associated with Klippel-Feil Syndrome: a case series. Klippel-Feil综合征的影像学和临床表现:一个病例系列。
IF 1.6
Spine deformity Pub Date : 2025-07-01 Epub Date: 2025-04-14 DOI: 10.1007/s43390-025-01072-5
Gabrielle Santangelo, Andrew Megas, Aniruddh Mandalapu, Ram Haddas, Addisu Mesfin
{"title":"Radiographic and clinical findings associated with Klippel-Feil Syndrome: a case series.","authors":"Gabrielle Santangelo, Andrew Megas, Aniruddh Mandalapu, Ram Haddas, Addisu Mesfin","doi":"10.1007/s43390-025-01072-5","DOIUrl":"10.1007/s43390-025-01072-5","url":null,"abstract":"<p><strong>Objectives: </strong>To characterize the patient demographics, medical comorbidities, spinal anatomic characteristics, and surgical management of patients with Klippel-Feil Syndrome (KFS).</p><p><strong>Methods: </strong>An institutional billing database was used to identify patients with KFS, which was confirmed by the authors' review of imaging. The patient data were categorized by patient demographics, medical comorbidities, spinal anatomic characteristics, and surgical management.</p><p><strong>Results: </strong>In our cohort of 93 patients with KFS, more females than males (53% vs 47%) were affected. The mean age was 46 years old. The most common levels of fusion were C2-C3 (15%) and C5-C6 (13%). Following the Samartzis classification, 67% were type I, 14% were type II, and 22% were type III. There was a 29% occurence of scoliosis. Among those with scoliosis, 27% were diagnosed in adolescence, 40% had scoliosis in the cervical region, 20% thoracic, and 20% lumbar. A total of 26% of patients underwent spine surgery primarily for stenosis (6/24) and myelopathy (5/24). Of the spine surgeries, 58.3% were posterior-based procedures, 16.7% anterior and posterior-based procedures, 12.5% anterior-based procedures, 8.3% of patients had a spinal discectomy, and 1 patient underwent a torticollis release. A total of 18 out of 24 of the surgical procedures (75%) were at or adjacent to the level of congenital fusion.</p><p><strong>Conclusion: </strong>KFS is commonly associated with degenerative changes, neural compression, and traumatic instability in intervertebral discs adjacent to fused vertebrae. Surgical intervention in patient with KFS largely involved posterior spinal fusions involving or adjacent to levels of congenital vertebral fusions.</p>","PeriodicalId":21796,"journal":{"name":"Spine deformity","volume":" ","pages":"1189-1195"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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