Singapore medical journal最新文献_第7页

Percutaneous iliosacral screw fixation of sacral U-type fracture using a mid-foot intramedullary bolt: a case report 使用中足髓内栓经皮髂骶螺钉固定骶骨 U 型骨折：病例报告

IF 2.7 4区医学

Singapore medical journal Pub Date : 2024-01-08 DOI: 10.4103/singaporemedj.smj-2021-172

Peng Lee, Yong Sheng Chen, Amritpal Singh, Antony Gardner

引用次数: 0

Femoral neck system as a safe alternative to cannulated compression screw and dynamic hip screw in femoral neck fractures: an early comparative study 股骨颈系统在股骨颈骨折中作为插管加压螺钉和动态髋螺钉的安全替代品：早期比较研究

IF 2.7 4区医学

Singapore medical journal Pub Date : 2024-01-08 DOI: 10.4103/singaporemedj.smj-2022-024

Zhe Zheng Clyde Lim, Cheryl Marise Peilin Tan, Rex Premchand Antony Xavier, M. G. J. Yam, I. T. Chua

{"title":"Femoral neck system as a safe alternative to cannulated compression screw and dynamic hip screw in femoral neck fractures: an early comparative study","authors":"Zhe Zheng Clyde Lim, Cheryl Marise Peilin Tan, Rex Premchand Antony Xavier, M. G. J. Yam, I. T. Chua","doi":"10.4103/singaporemedj.smj-2022-024","DOIUrl":"https://doi.org/10.4103/singaporemedj.smj-2022-024","url":null,"abstract":"\u0000 \u0000 \u0000 The femoral neck system (FNS) is a safe alternative to cannulated compression screw (CCS) and dynamic hip screw (DHS) in femoral neck fractures.\u0000 \u0000 \u0000 \u0000 A dual-centre retrospective cohort study was performed on femoral neck fractures (AO type 31-B) treated with closed reduction and internal fixation using FNS, DHS or CCS between April 2016 and April 2020. Exclusion criteria were as follows: patients aged below 16 years; chronic fractures beyond 7 days; pathological fractures; fracture extension to the intertrochanteric region or ipsilateral neck and shaft fractures; and open fractures. A total of 85 patients were identified: FNS (n = 28), DHS (n = 29) and CCS (n = 28).\u0000 \u0000 \u0000 \u0000 The FNS and CCS groups had a lower Garden and Pauwels classification compared to the DHS group (both P < 0.001). Both FNS and CCS groups were comparable in postoperative orthopaedic complications (10.7% [n = 3] vs. 3.6% [n = 1], adjusted P = 0.321). The DHS group had more postoperative orthopaedic complications than the FNS group, but this was not statistically significant (27.6% [n = 8] vs. 10.7% [n = 3], adjusted P = 0.321). There were no significant differences in median time to radiological union or median femoral neck shortening at union (both P > 0.05) among the three groups.\u0000 \u0000 \u0000 \u0000 The new DePuy Synthes FNS is a safe alternative to CCS with comparable complication rates for femoral neck fractures that are less displaced and more stable. The FNS also appears to be a safe alternative to DHS in the fixation of femoral neck fractures for the few cases of high-energy femoral neck fractures.\u0000","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":"57 48","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139447147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful treatment of psoriasis-associated uveitis with ixekizumab after failure of secukinumab and risankizumab 在secukinumab和risankizumab治疗失败后使用ixekizumab成功治疗银屑病相关葡萄膜炎

IF 2.7 4区医学

Singapore medical journal Pub Date : 2024-01-02 DOI: 10.4103/singaporemedj.smj-2023-133

Angelyn Chen Yin Lua, Soon-Phaik Chee, Hazel Hwee Boon Oon

引用次数: 0

Jarisch–Herxheimer reaction in a patient with Weil’s disease 一名魏尔病患者的雅利什-赫克海默反应

IF 2.7 4区医学

Singapore medical journal Pub Date : 2024-01-02 DOI: 10.4103/singaporemedj.smj-2022-196

J. N. Ngiam, Tiara Joy Foo, Genevieve MY Tan, Jason Phua, Hui Fang Lim, P. Tambyah, G. Yan

引用次数: 0

Characteristics of patients who received Sinopharm BIPB vaccine in Singapore general practice 在新加坡全科诊所接种国药集团 BIPB 疫苗的患者特征

IF 2.7 4区医学

Singapore medical journal Pub Date : 2024-01-02 DOI: 10.4103/singaporemedj.smj-2022-082

E. Chng, Aloysius Chow, Helen Elizabeth Smith

引用次数: 0

Potential hurdles to prescribing COVID-19 oral antivirals in primary and community care 基层和社区医疗机构开具 COVID-19 口服抗病毒药物处方的潜在障碍

IF 2.7 4区医学

Singapore medical journal Pub Date : 2024-01-02 DOI: 10.4103/singaporemedj.smj-2023-054

Martin Yong Kwong Lee, Deanna Xiuting Koh, S. Chong, R. Chua

引用次数: 0

Medical and social domains of ageing research in Singapore (2008-2018): a scoping review. 新加坡老龄化的医学和社会领域研究（2008-2018 年）：范围综述。

IF 1.7 4区医学

Singapore medical journal Pub Date : 2024-01-01 Epub Date: 2021-10-31 DOI: 10.11622/smedj.2021172

Chen Hee Tam, Elaine Qiao Ying Ho, Sumali Subhashini Hewage, Shilpa Tyagi, Gerald Choon Huat Koh

{"title":"Medical and social domains of ageing research in Singapore (2008-2018): a scoping review.","authors":"Chen Hee Tam, Elaine Qiao Ying Ho, Sumali Subhashini Hewage, Shilpa Tyagi, Gerald Choon Huat Koh","doi":"10.11622/smedj.2021172","DOIUrl":"10.11622/smedj.2021172","url":null,"abstract":"Introduction: This scoping review examined the number, types and characteristics of journal publications on ageing in Singapore from 2008 to 2018 to determine how ageing research in medical and social domains in Singapore has transformed over time.Methods: Using relevant search terms, articles were extracted from multiple databases and then screened and reviewed for eligibility and inclusion by independent reviewers. Data such as article title, authors, year of publication, name of journal, type of journal, study design and the kind of data used were charted from the included articles for evidence synthesis.Results: Since 2008, there has been a steady increase in the number of publications on ageing in medical and social domains in Singapore. In the medical domain, publications on Ophthalmology (22%) made up the largest proportion of the existing medical literature on ageing in Singapore, followed by Physical Functioning (17%), which involved physiological measurements of physical well-being, and Geriatrics (16%). Non-medical publications comprised 38% of all the included publications, with publications on the social aspects of ageing (43%) forming the largest group in this cluster, followed by publications on Prevention (19%) and Healthcare services (18%). The study design was mostly observational (82%), with only 3% of interventional studies.Conclusion: While ageing research had expanded in Singapore in the last decade, it was predominantly discipline specific and observational in design. As ageing issues are complex, with biology intersecting with psychology and sociology, we call for greater interdisciplinary collaboration, the conduct of more interventional studies, as well as more research in understudied and emerging areas.","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"30-37"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10863733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39575951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improving children's cooperativeness during magnetic resonance imaging using interactive educational animated videos: a prospective, randomised, non-inferiority trial. 利用互动教育动画视频提高儿童在磁共振成像过程中的合作能力：一项前瞻性、随机、非劣效试验。

IF 2.7 4区医学

Singapore medical journal Pub Date : 2024-01-01 Epub Date: 2021-10-07 DOI: 10.11622/smedj.2021141

Evelyn Gabriela Utama, Seyed Ehsan Saffari, Phua Hwee Tang

{"title":"Improving children's cooperativeness during magnetic resonance imaging using interactive educational animated videos: a prospective, randomised, non-inferiority trial.","authors":"Evelyn Gabriela Utama, Seyed Ehsan Saffari, Phua Hwee Tang","doi":"10.11622/smedj.2021141","DOIUrl":"10.11622/smedj.2021141","url":null,"abstract":"Introduction: A previous prospective, randomised controlled trial showed that animated videos shown to children before magnetic resonance imaging (MRI) scan reduced the proportion of children needing repeated MRI sequences and improved confidence of the children staying still for at least 30 min. Children preferred the interactive video. We hypothesised that the interactive video is non-inferior to showing two videos (regular and interactive) in improving children's cooperativeness during MRI scans.Methods: In this Institutional Review Board-approved prospective, randomised, non-inferiority trial, 558 children aged 3-20 years scheduled for elective MRI scan from June 2017 to March 2019 were randomised into the interactive video only group and combined (regular and interactive) videos group. Children were shown the videos before their scan. Repeated MRI sequences, general anaesthesia (GA) requirement and improvement in confidence of staying still for at least 30 min were assessed.Results: In the interactive video group ( n = 277), 86 (31.0%) children needed repeated MRI sequences, two (0.7%) needed GA and the proportion of children who had confidence in staying still for more than 30 min increased by 22.1% after the video. In the combined videos group ( n = 281), 102 (36.3%) children needed repeated MRI sequences, six (2.1%) needed GA and the proportion of children who had confidence in staying still for more than 30 min increased by 23.2% after the videos; the results were not significantly different between the two groups.Conclusion: The interactive video group demonstrated non-inferiority to the combined videos group.","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"9-15"},"PeriodicalIF":2.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10863732/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39517433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is non-contrast-enhanced magnetic resonance imaging cost-effective for screening of hepatocellular carcinoma? 非造影剂增强磁共振成像用于筛查肝细胞癌是否具有成本效益？

IF 2.7 4区医学

Singapore medical journal Pub Date : 2024-01-01 Epub Date: 2021-10-11 DOI: 10.11622/smedj.2021153

Genevieve Jingwen Tan, Chau Hung Lee, Yan Sun, Cher Heng Tan

{"title":"Is non-contrast-enhanced magnetic resonance imaging cost-effective for screening of hepatocellular carcinoma?","authors":"Genevieve Jingwen Tan, Chau Hung Lee, Yan Sun, Cher Heng Tan","doi":"10.11622/smedj.2021153","DOIUrl":"10.11622/smedj.2021153","url":null,"abstract":"Introduction: Ultrasonography (US) is the current standard of care for imaging surveillance in patients at risk of hepatocellular carcinoma (HCC). Magnetic resonance imaging (MRI) has been explored as an alternative, given the higher sensitivity of MRI, although this comes at a higher cost. We performed a cost-effective analysis comparing US and dual-sequence non-contrast-enhanced MRI (NCEMRI) for HCC surveillance in the local setting.Methods: Cost-effectiveness analysis of no surveillance, US surveillance and NCEMRI surveillance was performed using Markov modelling and microsimulation. At-risk patient cohort was simulated and followed up for 40 years to estimate the patients' disease status, direct medical costs and effectiveness. Quality-adjusted life years (QALYs) and incremental cost-effectiveness ratio were calculated.Results: Exactly 482,000 patients with an average age of 40 years were simulated and followed up for 40 years. The average total costs and QALYs for the three scenarios - no surveillance, US surveillance and NCEMRI surveillance - were SGD 1,193/7.460 QALYs, SGD 8,099/11.195 QALYs and SGD 9,720/11.366 QALYs, respectively.Conclusion: Despite NCEMRI having a superior diagnostic accuracy, it is a less cost-effective strategy than US for HCC surveillance in the general at-risk population. Future local cost-effectiveness analyses should include stratifying surveillance methods with a variety of imaging techniques (US, NCEMRI, contrast-enhanced MRI) based on patients' risk profiles.","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"23-29"},"PeriodicalIF":2.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10863734/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39503921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Time to intubation with McGrath ™ videolaryngoscope versus direct laryngoscope in powered air-purifying respirator: a randomised controlled trial. 在动力空气净化呼吸器中使用 McGrath ™ 视频喉镜与直接喉镜的插管时间：随机对照试验。

IF 2.7 4区医学

Singapore medical journal Pub Date : 2024-01-01 Epub Date: 2021-10-24 DOI: 10.11622/smedj.2021165

Qing Yuan Goh, Sui An Lie, Zihui Tan, Pei Yi Brenda Tan, Shin Yi Ng, Hairil Rizal Abdullah

{"title":"Time to intubation with McGrath ™ videolaryngoscope versus direct laryngoscope in powered air-purifying respirator: a randomised controlled trial.","authors":"Qing Yuan Goh, Sui An Lie, Zihui Tan, Pei Yi Brenda Tan, Shin Yi Ng, Hairil Rizal Abdullah","doi":"10.11622/smedj.2021165","DOIUrl":"10.11622/smedj.2021165","url":null,"abstract":"Introduction: During the coronavirus disease 2019 (COVID-19) pandemic, multiple guidelines have recommended videolaryngoscope (VL) for tracheal intubation. However, there is no evidence that VL reduces time to tracheal intubation, and this is important for COVID-19 patients with respiratory failure.Methods: To simulate intubation of COVID-19 patients, we randomly assigned 28 elective surgical patients to be intubated with either McGrath™ MAC VL or direct laryngoscope (DL) by specialist anaesthetists who donned 3M™ Jupiter™ powered air-purifying respirators (PAPR) and N95 masks. The primary outcome was time to intubation.Results: The median time to intubation was 61 s (interquartile range [IQR] 37-63 s) and 41.5 s (IQR 37-56 s) in the VL and DL groups, respectively ( P = 0.35). The closest mean distance between the anaesthetist and patient during intubation was 21.6 ± 4.8 cm and 17.6 ± 5.3 cm in the VL and DL groups, respectively ( P = 0.045). There were no significant differences in the median intubation difficulty scale scores, proportion of successful intubations at the first laryngoscopic attempt and proportion of intubations requiring adjuncts. All the patients underwent successful intubation with no adverse event.Conclusion: There was no significant difference in the time to intubation of elective surgical patients with either McGrath™ VL or DL by specialist anaesthetists who donned PAPR and N95 masks. The distance between the anaesthetist and patient was significantly greater with VL. When resources are limited or disrupted during a pandemic, DL could be a viable alternative to VL for specialist anaesthetists.","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"2-8"},"PeriodicalIF":2.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10863731/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39550053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0