Skeletal Muscle最新文献

{"title":"Two functional variants at 6p21.1 were associated with lean mass","authors":"Yu-Fang Pei, Wen-Zhu Hu, Xiao-Lin Yang, Xin-Tong Wei, Gui-Juan Feng, Hong Zhang, Hui Shen, Q. Tian, H. Deng, Lei Zhang","doi":"10.1186/s13395-019-0212-3","DOIUrl":"https://doi.org/10.1186/s13395-019-0212-3","url":null,"abstract":"","PeriodicalId":21747,"journal":{"name":"Skeletal Muscle","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2019-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13395-019-0212-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42035426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barium chloride injures myofibers through calcium-induced proteolysis with fragmentation of motor nerves and microvessels","authors":"Aaron B. Morton, C. Norton, N. Jacobsen, Charmain A. Fernando, D. Cornelison, S. Segal","doi":"10.1186/s13395-019-0213-2","DOIUrl":"https://doi.org/10.1186/s13395-019-0213-2","url":null,"abstract":"","PeriodicalId":21747,"journal":{"name":"Skeletal Muscle","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2019-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13395-019-0213-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49456704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"LIM and cysteine-rich domains 1 (LMCD1) regulates skeletal muscle hypertrophy, calcium handling, and force","authors":"D. Ferreira, A. Cheng, A. Cheng, Leandro Z. Agudelo, Leandro Z. Agudelo, I. Červenka, T. Chaillou, T. Chaillou, J. Correia, Margareta Porsmyr-Palmertz, M. Izadi, Alicia Hansson, Vicente Martínez-Redondo, Paula Valente-Silva, Amanda T. Pettersson-Klein, J. Estall, M. Robinson, K. Nair, J. Lanner, J. Ruas","doi":"10.1186/s13395-019-0214-1","DOIUrl":"https://doi.org/10.1186/s13395-019-0214-1","url":null,"abstract":"","PeriodicalId":21747,"journal":{"name":"Skeletal Muscle","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2019-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13395-019-0214-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42838714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Defective angiogenesis in CXCL12 mutant mice impairs skeletal muscle regeneration","authors":"D. Hardy, Mylène Fefeu, Aurore Besnard, David Briand, P. Gasse, F. Arenzana‐Seisdedos, P. Rocheteau, F. Chrétien","doi":"10.1186/s13395-019-0210-5","DOIUrl":"https://doi.org/10.1186/s13395-019-0210-5","url":null,"abstract":"","PeriodicalId":21747,"journal":{"name":"Skeletal Muscle","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2019-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13395-019-0210-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42217089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunohistochemical phenotyping of T cells, granulocytes, and phagocytes in the muscle of cancer patients: association with radiologically defined muscle mass and gene expression","authors":"A. Añoveros-Barrera, A. Bhullar, C. Stretch, A. Dunichand-Hoedl, K. Martins, A. Rieger, D. Bigam, T. McMullen, O. Bathe, C. T. Putman, C. Field, V. Baracos, V. Mazurak","doi":"10.1186/s13395-019-0209-y","DOIUrl":"https://doi.org/10.1186/s13395-019-0209-y","url":null,"abstract":"","PeriodicalId":21747,"journal":{"name":"Skeletal Muscle","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2019-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13395-019-0209-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41736515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ibuprofen inhibited migration of skeletal muscle cells in association with downregulation of p130cas and CrkII expressions","authors":"Chih-Hao Liao, Li-Ping Lin, Tung-Yang Yu, Chih-Chin Hsu, Jong‐Hwei S. Pang, W. Tsai","doi":"10.1186/s13395-019-0208-z","DOIUrl":"https://doi.org/10.1186/s13395-019-0208-z","url":null,"abstract":"","PeriodicalId":21747,"journal":{"name":"Skeletal Muscle","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2019-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13395-019-0208-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42149816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"miR-146a deficiency does not aggravate muscular dystrophy in mdx mice","authors":"Iwona Bronisz-Budzyńska, Katarzyna Chwalenia, Olga Mucha, P. Podkalicka, Karolina-Bukowska-Strakova, A. Józkowicz, A. Łoboda, M. Kozakowska, J. Dulak","doi":"10.1186/s13395-019-0207-0","DOIUrl":"https://doi.org/10.1186/s13395-019-0207-0","url":null,"abstract":"","PeriodicalId":21747,"journal":{"name":"Skeletal Muscle","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2019-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13395-019-0207-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48350974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NAD+ improves neuromuscular development in a zebrafish model of FKRP-associated dystroglycanopathy","authors":"E. Bailey, Sarah S. Alrowaished, Elisabeth A. Kilroy, Emma S. Crooks, Daisy M. Drinkert, Chaya M. Karunasiri, Joseph J. Belanger, A. Khalil, Joshua B. Kelley, C. Henry","doi":"10.1186/s13395-019-0206-1","DOIUrl":"https://doi.org/10.1186/s13395-019-0206-1","url":null,"abstract":"","PeriodicalId":21747,"journal":{"name":"Skeletal Muscle","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2019-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13395-019-0206-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46646228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estrogen signaling effects on muscle-specific immune responses through controlling the recruitment and function of macrophages and T cells","authors":"Zhaohong Liao, Tao Huang, Jiangwei Xiao, Ruicai Gu, Jun Ouyang, Gang Wu, Hua Liao","doi":"10.1186/s13395-019-0205-2","DOIUrl":"https://doi.org/10.1186/s13395-019-0205-2","url":null,"abstract":"","PeriodicalId":21747,"journal":{"name":"Skeletal Muscle","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2019-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13395-019-0205-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44335018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regulation of murine skeletal muscle growth by STAT5B is age- and sex-specific.","authors":"Ryan G Paul,&nbsp;Alex S Hennebry,&nbsp;Marianne S Elston,&nbsp;John V Conaglen,&nbsp;Chris D McMahon","doi":"10.1186/s13395-019-0204-3","DOIUrl":"https://doi.org/10.1186/s13395-019-0204-3","url":null,"abstract":"<p><strong>Background: </strong>Sexually dimorphic growth has been attributed to the growth hormone (GH)/insulin-like growth factor 1 (IGF1) axis, particularly GH-induced activation of the intracellular signal transducer and activator of transcription 5B (STAT5B), because deletion of STAT5B reduces body mass and the mass of skeletal muscles in male mice to that in female mice. However, it remains unclear why these effects are sex- and species-specific, because the loss of STAT5B retards growth in girls, but not in male mice. Our objectives were to determine whether sexually dimorphic growth of skeletal muscle persisted in STAT5B^-/- mice and investigate the mechanisms by which STAT5B regulates sexually dimorphic growth.</p><p><strong>Methods: </strong>Blood and skeletal muscle were harvested from male and female STAT5B^-/- mice and their wild-type littermates from the onset of puberty to adulthood.</p><p><strong>Results: </strong>Growth of the skeleton and skeletal muscles was retarded in both sexes of STAT5B^-/- mice, but more so in males. Although reduced, sexually dimorphic growth of skeletal muscle persisted in STAT5B^-/- mice with an oxidative shift in the composition of myofibres in both sexes. Concentrations of IGF1 in blood and skeletal muscle were reduced in male STAT5B^-/- mice at all ages, but only in female STAT5B^-/- mice at the onset of puberty. Expression of androgen receptor (AR) and oestrogen receptor alpha (ERα) mRNA and protein was reduced in skeletal muscles of male and female STAT5B^-/- mice, respectively. Loss of STAT5B abolished the sexually dimorphic expression of myostatin protein and Igf1, Ar, Erα, suppressor of cytokine signalling 2 (Socs2), and cytokine-inducible SH2-containing protein (Cis) mRNA in skeletal muscle.</p><p><strong>Conclusions: </strong>STAT5B appears to mediate GH signalling in skeletal muscles of male mice at all ages, but only until puberty in female mice. STAT5B also appears to mediate the actions of androgens and oestrogens in both male and female mice, but sexually dimorphic growth persists in STAT5B^-/- mice.</p>","PeriodicalId":21747,"journal":{"name":"Skeletal Muscle","volume":"9 1","pages":"19"},"PeriodicalIF":4.9,"publicationDate":"2019-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13395-019-0204-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37094681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}