Scottish Medical JournalPub Date : 2023-11-01Epub Date: 2023-07-14DOI: 10.1177/00369330231187655
Hui Gan, Jiarong Lan, Hongxia Bei, Guangxing Xu
{"title":"The impact of sarcopenia on prognosis of patients with pancreatic cancer: A systematic review and meta-analysis.","authors":"Hui Gan, Jiarong Lan, Hongxia Bei, Guangxing Xu","doi":"10.1177/00369330231187655","DOIUrl":"10.1177/00369330231187655","url":null,"abstract":"<p><strong>Objective: </strong>To summarize recent findings on the association of low skeletal muscle mass and muscle quality with overall survival and recurrence-free survival in patients with pancreatic cancer.</p><p><strong>Methods: </strong>A systematic search was conducted using Medline (via PubMed), Embase and Scopus databases for observational studies reporting on the overall survival and recurrence-free survival. Pooled effect sizes were reported as hazards ratio along with 95% confidence intervals.</p><p><strong>Results: </strong>A total of 34 studies were included. Low skeletal muscle index (indicating muscle mass) was associated with poor overall survival (hazards ratio: 1.50; 95% confidence interval: 1.34, 1.67) and lower recurrence-free survival (hazards ratio: 1.28, 95% confidence interval: 1.15, 1.43). Low skeletal muscle attenuation (indicating muscle quality) was associated with poor overall survival (hazards ratio: 1.32; 95% confidence interval: 1.05, 1.66). Recurrence-free survival was similar in patients with low and normal/high skeletal muscle attenuation (hazards ratio: 1.12, 95% confidence interval: 0.89, 1.40).</p><p><strong>Conclusion: </strong>Both low skeletal muscle mass and poor muscle quality are associated with poor long-term survival. Low skeletal muscle index, but not low skeletal muscle attenuation, are associated with poor recurrence-free survival.</p>","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":" ","pages":"133-148"},"PeriodicalIF":1.4,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9832287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Do we need a co-pilot in the operating theatre? A cross-sectional study on surgeons' perceptions.","authors":"Priyal Taribagil, Timing Liu, Vish Bhattacharya, Sanjay Taribagil","doi":"10.1177/00369330231207989","DOIUrl":"10.1177/00369330231207989","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this original study was to investigate general surgeons' perceptions on the role of dual surgeon operating for high-risk, elective complex surgical procedures.</p><p><strong>Material and methods: </strong>A 21-part cross-sectional online survey was self-completed by 85 general surgeons across hospitals in the UK. The survey assessed the perception of dual surgeon operating on patient morbidity and mortality, surgeons' burnout rates, complaints, patient waiting times and overall trainee experience. Statistical analysis was performed using R version 3.6.1.</p><p><strong>Results: </strong>Overall 78.8% believed that dual surgeon operating could help to overcome these human factors. Sub-analysis includes improve surgeon fatigue (89.4%), improve confidence (83.5%), improve decision-making (76.5%), minimise technical error (69.4%), improve communication, team work and leadership skills (65.9%). 65.9% believed it would reduce surgeons' burnout. There was a statistically significant relationship between the participants believing it would reduce surgeons' burnout and those who felt it would reduce complaints, Chi-squared(4) = [30.8], <i>p</i> = [0.00000342]. A statistically significant relationship was noted between participants believing it would reduce surgeons' burnout and those who felt it would reduce patient mortality/morbidity, Chi-squared(4) = [19.9], <i>p</i> = [0.000517].</p><p><strong>Conclusion: </strong>The survey has highlighted positive surgeons' perceptions regarding dual surgeon operating.</p>","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":" ","pages":"166-174"},"PeriodicalIF":2.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41238343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RETRACTED: Erector spinae plane block for pain control after hip surgeries: A systematic review and meta-analysis.","authors":"Haiyan Pan, Guofang Fei","doi":"10.1177/00369330231193624","DOIUrl":"10.1177/00369330231193624","url":null,"abstract":"","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":" ","pages":"369330231193624"},"PeriodicalIF":2.7,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9945358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Scottish Medical JournalPub Date : 2023-08-01Epub Date: 2023-05-07DOI: 10.1177/00369330231174231
Sisith Ariyaratne, Rajesh Botchu, Karthikeyan P Iyengar
{"title":"ChatGPT in academic publishing: An ally or an adversary?","authors":"Sisith Ariyaratne, Rajesh Botchu, Karthikeyan P Iyengar","doi":"10.1177/00369330231174231","DOIUrl":"10.1177/00369330231174231","url":null,"abstract":"subsequent Academic Publishing","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":"68 3","pages":"129-130"},"PeriodicalIF":2.7,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10529702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Scottish Medical JournalPub Date : 2023-08-01Epub Date: 2023-05-31DOI: 10.1177/00369330231178910
Hui Sun, Qifeng Lv, Tingting Liu, Nan Zhang, Fengfeng Shi
{"title":"Diagnostic accuracy of cervical elastography for predicting preterm delivery: Systematic review and meta-analysis.","authors":"Hui Sun, Qifeng Lv, Tingting Liu, Nan Zhang, Fengfeng Shi","doi":"10.1177/00369330231178910","DOIUrl":"10.1177/00369330231178910","url":null,"abstract":"<p><strong>Objective: </strong>Cervical elastography has been used in pregnant women to diagnose preterm births. However, there is a variability in the measured elasticity parameters and imaging mode used. We evaluated the precision of cervical elastography in identifying preterm births.</p><p><strong>Methods: </strong>Extensive and methodical searches were made in the databases such as Scopus, Embase, Cochrane Library, PubMed Central, Medline, ScienceDirect, and Google Scholar from the inception until November 2022, for studies that report diagnostic accuracy of cervical elastography for preterm deliveries in antenatal women.</p><p><strong>Results: </strong>The pooled sensitivity and specificity value of cervical elastography for preterm deliveries were 82% (95%CI: 73%-89%) and 77% (95%CI: 64%-86%), respectively with area under curve (AUC) of 0.87 (95%CI: 0.72-0.95). The diagnostic odds ratio (DOR) was 15 (95%CI: 8-28), positive likelihood ratio (LRP) was 3.5 (95%CI: 2.3-5.5) and negative likelihood ratio LRN was 0.23 (0.16-0.34). Pooled sensitivity and specificity of shear wave elastography was 88% and 71%, respectively. Pooled sensitivity and specificity of strain elastography was 80% and 79%, respectively. Heterogeneity was significant, as indicated by chi-square test and an I<sup>2</sup> statistic of over 75.</p><p><strong>Conclusions: </strong>Cervical elastography can be used for predicting preterm deliveries with moderate to high level of accuracy.</p>","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":"68 3","pages":"110-120"},"PeriodicalIF":2.7,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10529738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Scottish Paediatric Society St Andrew's Day Paediatric Symposium Friday 12th November 2021.","authors":"","doi":"10.1177/00369330231187717","DOIUrl":"10.1177/00369330231187717","url":null,"abstract":"Background: Children with Down syndrome (DS) are at increased risk of coeliac disease (CD). Current screening practice in DS includes tissue transglutaminase IgA (TGA-IgA) serology. There is no standard UK guidance on the frequency of serology testing or inclusion of HLA-typing for CD predisposing antigens, DQ2 and DQ8. HLA testing can be performed before gluten exposure and to coincide with other routine investigations. A negative DQ2/DQ8 type means patients do not require further coeliac screening. A positive DQ2/DQ8 type allows risk strati fi cation of patients. We explored the cost-effectiveness and family acceptance of a screening strategy that involved both serology and HLA-typing of children with DS. Methods","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":"68 3","pages":"NP1-NP5"},"PeriodicalIF":2.7,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10196944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ST ANDREW'S DAY PAEDIATRIC SYMPOSIUM Friday 25th November 2022 Royal College of Physicians and Surgeons of Glasgow.","authors":"","doi":"10.1177/00369330231187720","DOIUrl":"10.1177/00369330231187720","url":null,"abstract":"Background: High-fl ow nasal cannula oxygen (HFNCO) therapy is a well-recognised therapy to provide respiratory support to infants with bronchiolitis. It has been provided on the general paediatric receiving ward in the Royal Hospital for Children (RHC), Glasgow for 3 years, having previously been delivered only in Paediatric Intensive Care Unit (PICU). Due to COVID-19 the requirement for PICUsto have a contingency plan to increase critical care capacity and initiate changes in critical care practice high-lighted the importance of providing ward-based HFNC. Aims: To ascertain the effectiveness and safety of using HFNC within the ward setting and establish the number of PICU days saved. Methodology:","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":"68 3","pages":"NP17-NP20"},"PeriodicalIF":2.7,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10587597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Can peritumoral edema evaluated by Magnetic Resonance Imaging before neoadjuvant chemotherapy predict complete pathological response in breast cancer?","authors":"Burcak Cakir Pekoz, Okan Dilek, Tolga Koseci, Zeynel Abidin Tas, Oktay Irkorucu, Bozkurt Gulek","doi":"10.1177/00369330231174230","DOIUrl":"https://doi.org/10.1177/00369330231174230","url":null,"abstract":"<p><strong>Background and aims: </strong>The complete pathological response (pCR) following neoadjuvant chemotherapy (NAC) in breast cancer is essential for the accurate prediction of prognosis. We aimed to evaluate the efficacy of the presence and type of peritumoral edema detected by magnetic resonance imaging (MRI) in predicting pCR to NAC in breast cancer patients.</p><p><strong>Methods and results: </strong>One hundred five patients with the diagnosis of invasive carcinoma were evaluated by MRI before NAC. Edema was evaluated in fat-suppressed T2-weighted images. The patients were categorized into three groups: patients with no peritumoral edema, patients with peritumoral edema, and patients demonstrating subcutaneous edema. The cases were categorized as being pCR and non-pCR. Molecular subtypes, lymphovascular invasion (LVI), tumor size, and apparent diffusion coefficient (ADC) were evaluated. A positive relationship was found between the presence of edema and tumor size. Subcutaneous edema was found to be statistically higher in non-pCR patients. While the number of pCR patients with subcutaneous edema was 17 (30.4%), the number of non-pCR patients with subcutaneous edema was 26 (53.1%) (<i>p</i> = 0.018). LVI was found to be statistically higher in patients with edema. The number of edema-negative and LVI (+) patients was 4 (15.4%), while the number of edema-positive and LVI (+) patients was 28 (35.4%) (<i>p</i> = 0.042). Intratumoral and peritumoral ADC values were significantly higher in tumors with edema.</p><p><strong>Conclusion: </strong>The presence of subcutaneous edema and LVI may be utilized for the prediction of pCR outcomes in breast cancer patients scheduled for NAC treatment.</p>","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":"68 3","pages":"121-128"},"PeriodicalIF":2.7,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10178456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Scottish Medical JournalPub Date : 2023-08-01Epub Date: 2023-05-30DOI: 10.1177/00369330231178909
Ping Liu, Fang Cao, Qian Yao, Lin Xu, Hao Dai
{"title":"Effectiveness of educational and training intervention for improving hand hygiene compliance amongst nurses: a systematic review and meta-analysis of randomised controlled trials.","authors":"Ping Liu, Fang Cao, Qian Yao, Lin Xu, Hao Dai","doi":"10.1177/00369330231178909","DOIUrl":"10.1177/00369330231178909","url":null,"abstract":"<p><strong>Background and aims: </strong>Developing and implementing an educational and training programmes for improving hand hygiene compliance of the nursing personnel might help in increasing their knowledge, promoting positive attitude and follow adequate practice measures.</p><p><strong>Material and methods: </strong>Systematic search was done in PubMed, SCOPUS, CENTRAL, EMBASE, ScienceDirect, Clinicaltrials.gov and Google Scholar databases for articles published between 1964 and December 2022. Meta-analysis was carried out using a random-effects model, and the results were reported as pooled risk ratio (RR) with 95% confidence intervals (CIs), pooled standardised mean differences (SMD) or risk ratios (RR).</p><p><strong>Results: </strong>Eight studies were included in the analysis. Most studies had higher risk of bias. Nurses receiving educational and training programmes had significantly higher compliance to hand hygiene practices (pooled RR of 1.69 [95% CI: 1.23-2.31; I<sup>2</sup> = 99.1%], p = 0.001). The pooled analysis based on studies reporting the compliance to hand hygiene as continuous outcome has reported the pooled SMD as 1.28 with 95% CI: 0.62 to 1.95 and I<sup>2</sup> = 74.5%. There were no single-study effects with respect to this outcome, since the sensitivity analysis showed no difference in either direction or strength of effect estimate.</p><p><strong>Conclusion: </strong>Educational and training programmes are effective in improving the hand hygiene compliance amongst the nursing professionals.</p>","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":"68 3","pages":"72-79"},"PeriodicalIF":2.7,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10176068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Scottish Medical JournalPub Date : 2023-08-01Epub Date: 2023-07-25DOI: 10.1177/00369330231188962
Lanqin Gao, Yazhen Zhan, Xingping Hu, Shuli Liao
{"title":"Platelet-lymphocyte ratio and lymphocyte-monocyte ratio in inflammatory bowel disease and disease activity: A systematic review and meta-analysis.","authors":"Lanqin Gao, Yazhen Zhan, Xingping Hu, Shuli Liao","doi":"10.1177/00369330231188962","DOIUrl":"10.1177/00369330231188962","url":null,"abstract":"<p><strong>Objective: </strong>This review aimed to examine if the platelet-lymphocyte ratio and lymphocyte-monocyte ratio can be useful in determining disease activity in patients with inflammatory bowel disease.</p><p><strong>Methods: </strong>PubMed, CENTRAL, Scopus, Embase, and Web of Science were searched for studies published up to 9 January 2023. Platelet-lymphocyte ratio and lymphocyte-monocyte ratio values from active and remission inflammatory bowel disease cases were compared to generate a mean difference (MD).</p><p><strong>Results: </strong>Nine studies were included. Meta-analysis showed that inflammatory bowel disease patients with active disease had significantly higher values of platelet-lymphocyte ratio as compared to those in remission (MD: 63.46 95% CI: 35.74, 91.17, <i>I</i><sup>2 </sup>= 89%). The values of platelet-lymphocyte ratio were significantly higher in both active ulcerative colitis and Crohn's disease patients. Meta-analysis also showed that lymphocyte-monocyte ratio values were significantly lower in active inflammatory bowel disease patients as compared to those under remission (MD: -1.28 95% CI: -1.42, -1.14, <i>I</i><sup>2 </sup>= 4%). Lymphocyte-monocyte ratio values were significantly lower in both ulcerative colitis and Crohn's disease patients with active disease.</p><p><strong>Conclusion: </strong>Platelet-lymphocyte ratio and lymphocyte-monocyte ratio can be useful blood-based markers in differentiating active disease in inflammatory bowel disease patients. Active cases of ulcerative colitis and Crohn's disease have high platelet-lymphocyte ratio and low lymphocyte-monocyte ratio as compared to those in remission. Further studies with a larger sample size are needed to strengthen conclusions.</p>","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":"68 3","pages":"101-109"},"PeriodicalIF":2.7,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10178494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}