Can inflammatory indexes predict the spontaneous passage of common bile duct stones?

IF 1.4 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Scottish Medical Journal Pub Date : 2023-11-01 Epub Date: 2023-09-11 DOI:10.1177/00369330231186434

İrfan Küçük, Yusuf Yazgan, Ersin Tural, İdris Yıldırım, Tuğba Akbaş Şimşek, Başak Çakır Güney, Mustafa Kaplan

{"title":"Can inflammatory indexes predict the spontaneous passage of common bile duct stones?","authors":"İrfan Küçük, Yusuf Yazgan, Ersin Tural, İdris Yıldırım, Tuğba Akbaş Şimşek, Başak Çakır Güney, Mustafa Kaplan","doi":"10.1177/00369330231186434","DOIUrl":null,"url":null,"abstract":"Objectives: We aimed to determine whether inflammatory indexes (II), including the neutrophil-lymphocyte ratio (NLR), the C-reactive protein (CRP) to albumin ratio (CAR), the CRP-lymphocyte ratio (CLR), and the systemic immune-inflammation index (SIII) can be diagnostic for common bile duct stones (CBDSs) excretion before endoscopic retrograde cholangiopancreatography (ERCP).Backgrounds: Because of the spontaneous clearance, it is mandatory to ascertain the presence of CBDSs before ERCP.Methods: Retrospectively, we evaluated two groups. Group A included 96 records in which CBDSs existed in magnetic resonance cholangiopancreatography (MRCP) and ERCP. Group B included 36 records in which CBDSs existed in MRCP but not ERCP. IIs were calculated on presentation and before ERCP.Results: Stone detection in ERCP had a 3.992-fold (95% 1.769-9.007) higher probability with a stone larger than 3.25 mm in MRCP. Before ERCP, CAR, and CLR values were higher in group A than in group B (3.88 [1.25-14.14] and 1.24 [0.50-9.66], p = 0.027 versus 8.79 [2.19-35] and 2.67 [1.02-20.05], p = 0.029, respectively). Higher CRP, CAR, and CLR values were considered significant for detecting a stone in ERCP (AUC: 0.627 [0.519-0.739], 0.625 [0.513-0.737], and 0.624 [0.514-0.734], respectively).Conclusion: Low CRP, CAR, and CLR values might associate with the spontaneous migration of CBDS.","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":" ","pages":"159-165"},"PeriodicalIF":1.4000,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Scottish Medical Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/00369330231186434","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/9/11 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

Abstract

Objectives: We aimed to determine whether inflammatory indexes (II), including the neutrophil-lymphocyte ratio (NLR), the C-reactive protein (CRP) to albumin ratio (CAR), the CRP-lymphocyte ratio (CLR), and the systemic immune-inflammation index (SIII) can be diagnostic for common bile duct stones (CBDSs) excretion before endoscopic retrograde cholangiopancreatography (ERCP).

Backgrounds: Because of the spontaneous clearance, it is mandatory to ascertain the presence of CBDSs before ERCP.

Methods: Retrospectively, we evaluated two groups. Group A included 96 records in which CBDSs existed in magnetic resonance cholangiopancreatography (MRCP) and ERCP. Group B included 36 records in which CBDSs existed in MRCP but not ERCP. IIs were calculated on presentation and before ERCP.

Results: Stone detection in ERCP had a 3.992-fold (95% 1.769-9.007) higher probability with a stone larger than 3.25 mm in MRCP. Before ERCP, CAR, and CLR values were higher in group A than in group B (3.88 [1.25-14.14] and 1.24 [0.50-9.66], p = 0.027 versus 8.79 [2.19-35] and 2.67 [1.02-20.05], p = 0.029, respectively). Higher CRP, CAR, and CLR values were considered significant for detecting a stone in ERCP (AUC: 0.627 [0.519-0.739], 0.625 [0.513-0.737], and 0.624 [0.514-0.734], respectively).

Conclusion: Low CRP, CAR, and CLR values might associate with the spontaneous migration of CBDS.

查看原文本刊更多论文

炎症指标能否预测胆总管结石的自发通过?

目的:我们旨在确定炎症指标(II)，包括中性粒细胞-淋巴细胞比率(NLR)， c反应蛋白(CRP)与白蛋白比率(CAR)， CRP-淋巴细胞比率(CLR)和全身免疫炎症指数(SIII)是否可以在内镜逆行胆管造影术(ERCP)前诊断胆总管结石(cbds)排泄。背景:由于自发性清除，在ERCP前必须确定cbds的存在。方法:回顾性评价两组患者。A组包括96例磁共振胆管造影(MRCP)和ERCP中存在cbds的记录。B组包括36例MRCP存在cbds而ERCP不存在cbds的记录。在提交时和ERCP前计算i。结果:MRCP结石大于3.25 mm时，ERCP结石检出率比MRCP高3.992倍(95% 1.769 ~ 9.007)。ERCP前，A组CAR、CLR值均高于B组(分别为3.88[1.25-14.14]、1.24 [0.50-9.66]，p = 0.027、8.79[2.19-35]、2.67 [1.02-20.05]，p = 0.029)。较高的CRP、CAR和CLR值对于ERCP中结石的检测具有重要意义(AUC分别为0.627[0.519-0.739]、0.625[0.513-0.737]和0.624[0.514-0.734])。结论:低CRP、CAR和CLR值可能与CBDS的自发迁移有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Scottish Medical Journal 医学-医学：内科

CiteScore

4.80

自引率

3.70%

发文量

审稿时长

>12 weeks

期刊介绍： A unique international information source for the latest news and issues concerning the Scottish medical community. Contributions are drawn from Scotland and its medical institutions, through an array of international authors. In addition to original papers, Scottish Medical Journal publishes commissioned educational review articles, case reports, historical articles, and sponsoring society abstracts.This journal is a member of the Committee on Publications Ethics (COPE).