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黄芪提取液作为一款化妆品原料的功效评价 黄芪提取液作为一款化妆品原料的功效评价
2区 计算机科学
Science China Information Sciences Pub Date : 2025-03-25 DOI: 10.61369/cdcst.10467
令姗 孔, 川 伍, 云才 田
{"title":"黄芪提取液作为一款化妆品原料的功效评价","authors":"令姗 孔, 川 伍, 云才 田","doi":"10.61369/cdcst.10467","DOIUrl":"https://doi.org/10.61369/cdcst.10467","url":null,"abstract":"参考黄芪注射液制备方法制备黄芪提取液，对其中总糖含量进行测定，同时也进行初步的功效评价。研究结果显示，黄芪液中总糖含量为21.03 mg/mL；0.6250% 和1.2500%的黄芪液对LPS诱导的RAW264.7 巨噬细胞分泌的IL-6 mRNA表达量显著性降低；0.1000%和0.5000%的黄芪液对UVA诱导的3T3细胞中的Collagen-I和Collagen-Ⅲ在mRNA表达水平无显著上调作用。但能显著降低UVA诱导的3T3细胞中的MMP-1和MMP-3 mRNA的表达水平，并且显著抑制MMP-3 mRNA的表达水平，其中0.1000%黄芪液对MMP-3mRNA表达量的抑制率为71.34%。结果表明，黄芪提取液具有抗炎和延缓衰老的药理作用。","PeriodicalId":21618,"journal":{"name":"Science China Information Sciences","volume":"2 1","pages":"125-125"},"PeriodicalIF":0.0,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147913544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
山茶（Camellia japonica）花提取物在干性敏感皮肤中的舒缓修护功效研究 山茶（Camellia japonica）花提取物在干性敏感皮肤中的舒缓修护功效研究
2区 计算机科学
Science China Information Sciences Pub Date : 2025-03-25 DOI: 10.61369/cdcst.10460
建华 张, 文姣 郭, 娜 李, 青云 董, 垠 吴, 亚利 张
{"title":"山茶（Camellia japonica）花提取物在干性敏感皮肤中的舒缓修护功效研究","authors":"建华 张, 文姣 郭, 娜 李, 青云 董, 垠 吴, 亚利 张","doi":"10.61369/cdcst.10460","DOIUrl":"https://doi.org/10.61369/cdcst.10460","url":null,"abstract":"评估山茶花提取物（CJFE）及含有其的面霜在体内外的舒缓修护功效。体外结果：CJFE显著抑制TRPV1的表达（P＜0.05），降低斑马鱼皮肤屏障通透性（P＜0.05）。含3 wt%CJFE的面霜使3D表皮模型活细胞层厚度增加，促进丝聚蛋白（FLG）和兜甲蛋白（LOR）生成。临床结果：干敏志愿者使用该面霜4周后，面部MMV和TEWL值显著改善（p<0.05），a*值和敏感性显著降低（P＜0.05）。本研究表明CJFE具备舒缓修护功效，适用于干敏皮肤，为山茶花在化妆品领域的应用提供了依据。","PeriodicalId":21618,"journal":{"name":"Science China Information Sciences","volume":"2 1","pages":"73-73"},"PeriodicalIF":0.0,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147893495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Book review: Crosswinds: Nehru, Zhou and the Anglo-American Competition over China by Vijay Gokhale 书评：《侧风：尼赫鲁、周与英美对中国的竞争》，作者：Vijay Gokhale
2区 计算机科学
Science China Information Sciences Pub Date : 2025-02-28 DOI: 10.1177/0920203x251318173a
Ravi Ranjan Kumar
{"title":"Book review: <i>Crosswinds: Nehru, Zhou and the Anglo-American Competition over China</i> by Vijay Gokhale","authors":"Ravi Ranjan Kumar","doi":"10.1177/0920203x251318173a","DOIUrl":"https://doi.org/10.1177/0920203x251318173a","url":null,"abstract":"","PeriodicalId":21618,"journal":{"name":"Science China Information Sciences","volume":"39 1","pages":"128-129"},"PeriodicalIF":0.0,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://journals.sagepub.com/doi/pdf/10.1177/0920203X251318173a","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147908469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
基于网络药理学及体外实验探究中草药组方协同调节皮肤老化的作用机制 基于网络药理学及体外实验探究中草药组方协同调节皮肤老化的作用机制
2区 计算机科学
Science China Information Sciences Pub Date : 2024-11-25 DOI: 10.61369/cdcst.7983
春波 冯
{"title":"基于网络药理学及体外实验探究中草药组方协同调节皮肤老化的作用机制","authors":"春波 冯","doi":"10.61369/cdcst.7983","DOIUrl":"https://doi.org/10.61369/cdcst.7983","url":null,"abstract":"人体皮肤结构和稳态平衡被破坏的主要原因有真皮层细胞外基质蛋白降解、DNA损伤和氧化应激等因素。本文采用有皮肤抗衰老性能报道的中草药（Traditional Chinese Medicine ，TCM），探索其不同组合的组方，包括人参、黄精、桂花、昙花和莲，基于网络药理学预测不同TCM组方的潜在功效靶点和抗衰老机制，比较了不同组方在皮肤中的生物活性组间区别，探究了不同组方中草药的抗衰老效果。通过体外实验多维度验证不同组方在相同浓度下的协同作用。结果显示，五味中草药组方比人参、黄精、昙花三味组方以及单味人参，具有在胶原蛋白促生、SA-&amp;beta;-半乳糖苷酶降低、&amp;gamma;H2AX诱导的DNA损伤降低等方面更强的抗皮肤衰老效果。","PeriodicalId":21618,"journal":{"name":"Science China Information Sciences","volume":"1 2","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147886333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
拉曼光谱在皮肤角质层水合状态、结构与成分研究中的应用 拉曼光谱在皮肤角质层水合状态、结构与成分研究中的应用
2区 计算机科学
Science China Information Sciences Pub Date : 2024-11-25 DOI: 10.61369/cdcst.8003
文海 吴, 彬 王, 蕾蕾 职
{"title":"拉曼光谱在皮肤角质层水合状态、结构与成分研究中的应用","authors":"文海 吴, 彬 王, 蕾蕾 职","doi":"10.61369/cdcst.8003","DOIUrl":"https://doi.org/10.61369/cdcst.8003","url":null,"abstract":"拉曼光谱具有在体逐层检测的优势，已应用于产品安全、功效及物质经皮渗透等研究中。基于拉曼光谱应用特点，在皮肤水合状态方面，探讨了如何通过拉曼光谱研究角质层水分含量、结合水、非结合水等不同皮肤水分类型；在角质层结构和成分方面，探讨了如何通过拉曼光谱研究天然保湿因子、脂质、角质层蛋白质等皮肤成分与结构。运用拉曼光谱能深入研究角质层逐层的水合状态、结构与成分等，为化妆品功效评估及机理研究提供了新思路。","PeriodicalId":21618,"journal":{"name":"Science China Information Sciences","volume":"1 2","pages":"106-106"},"PeriodicalIF":0.0,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147916876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
忍冬不同部位提取物抗氧化活性研究及其在护肤品中的应用 忍冬不同部位提取物抗氧化活性研究及其在护肤品中的应用
2区 计算机科学
Science China Information Sciences Pub Date : 2024-09-25 DOI: 10.61369/cdcst.7088
萌萌 沈, 雨桐 王, 正扬 张, 领 王
{"title":"忍冬不同部位提取物抗氧化活性研究及其在护肤品中的应用","authors":"萌萌 沈, 雨桐 王, 正扬 张, 领 王","doi":"10.61369/cdcst.7088","DOIUrl":"https://doi.org/10.61369/cdcst.7088","url":null,"abstract":"以忍冬的花和茎叶为原料，分别以乙醇和水为提取溶剂，制备得到四种忍冬粗提物。采用细胞实验验证了提取物的安全性，通过自由基清除实验和人体功效评价实验对四种忍冬提取物的抗氧化能力进行了研究。结果表明：四种忍冬粗提物均无细胞毒性且具有一定的抗氧化能力。其中，水提法制备得到的忍冬茎叶提取物抗氧化能力最好，受试者在连续使用添加了忍冬茎叶水提物的护肤品28天后，皮肤粗糙度改善率为29.02%，皮肤皱纹改善率为18.27%。本研究为忍冬茎叶研究和在护肤品中的应用提供一定的数据支撑。","PeriodicalId":21618,"journal":{"name":"Science China Information Sciences","volume":"1 1","pages":"77-77"},"PeriodicalIF":0.0,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147895965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
An STP look at logical blocking of finite state machines: formulation, detection, and search 有限状态机逻辑阻塞的 STP 观察：表述、检测和搜索
IF 8.8 2区 计算机科学
Science China Information Sciences Pub Date : 2024-09-13 DOI: 10.1007/s11432-022-4124-7
Yongyi Yan, Penglei Hao, Jumei Yue, Haitao Li, Jun-E Feng
{"title":"An STP look at logical blocking of finite state machines: formulation, detection, and search","authors":"Yongyi Yan, Penglei Hao, Jumei Yue, Haitao Li, Jun-E Feng","doi":"10.1007/s11432-022-4124-7","DOIUrl":"https://doi.org/10.1007/s11432-022-4124-7","url":null,"abstract":"<p>The logical blocking of finite state machines (FSMs) is examined at the three levels of formulation, detection, and search from an STP viewpoint (semi-tensor product of matrices). The research idea regards an FSM as a logical system. The realizing method treats the event sequence exciting an FSM as the input signal of a logical system and treats the current states of an FSM as the states of a logical system. Based on a recently developed bilinear dynamic model of FSMs, a difference equation-like model is first proposed to describe the logical blocking. By defining a loop structure of FSMs and using the difference equation-like model, a criterion is built by which whether a given FSM is blocking can be easily judged. If it is, several algorithms are designed to find all the logical blocking of the FSM. Further, these results are extended to apply to the case of nondeterministic FSMs and, thus, to networks of FSMs. The proposed STP approach may provide a new angle for considering the problems of FSMs, and the presented results may strengthen the links between systems governed by human-designed rules and systems governed by natural laws.</p>","PeriodicalId":21618,"journal":{"name":"Science China Information Sciences","volume":"192 1","pages":""},"PeriodicalIF":8.8,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142252193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
State and parameter identification of linearized water wave equation via adjoint method 通过邻接法识别线性化水波方程的状态和参数
IF 8.8 2区 计算机科学
Science China Information Sciences Pub Date : 2024-09-13 DOI: 10.1007/s11432-023-4094-4
Yang Yu, Cheng-Zhong Xu, Hai-Long Pei, Jinpeng Yu
{"title":"State and parameter identification of linearized water wave equation via adjoint method","authors":"Yang Yu, Cheng-Zhong Xu, Hai-Long Pei, Jinpeng Yu","doi":"10.1007/s11432-023-4094-4","DOIUrl":"https://doi.org/10.1007/s11432-023-4094-4","url":null,"abstract":"<p>In this paper, we focus on the state and parameter identification problem of a hydrodynamical system. This system is modeled as a linearized water wave equation (LWWE), a hyperbolic state-space model coupled with a Laplace equation. We assume that the wave elevation at two distinct points is the only measurement of water waves. We show that the state and water depth can be reconstructed from this point measurement records. The identification problem is recast as an optimization problem over an infinite-dimensional space. We propose the adjoint method-based identification algorithm to generate an estimated state and water depth. We then performed a numerical simulation to show the effectiveness of our designed algorithm by comparing it with existing studies.</p>","PeriodicalId":21618,"journal":{"name":"Science China Information Sciences","volume":"3 1","pages":""},"PeriodicalIF":8.8,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142252192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
TSCompiler: efficient compilation framework for dynamic-shape models TSCompiler：动态形状模型的高效编译框架
IF 8.8 2区 计算机科学
Science China Information Sciences Pub Date : 2024-09-13 DOI: 10.1007/s11432-024-4071-6
Xiang Luo, Chen Zhang, Chenbo Geng, Yanzhi Yi, Jiahui Hu, Renwei Zhang, Zhen Zhang, Gianpietro Consolaro, Fan Yang, Tun Lu, Ning Gu, Li Shang
{"title":"TSCompiler: efficient compilation framework for dynamic-shape models","authors":"Xiang Luo, Chen Zhang, Chenbo Geng, Yanzhi Yi, Jiahui Hu, Renwei Zhang, Zhen Zhang, Gianpietro Consolaro, Fan Yang, Tun Lu, Ning Gu, Li Shang","doi":"10.1007/s11432-024-4071-6","DOIUrl":"https://doi.org/10.1007/s11432-024-4071-6","url":null,"abstract":"<p>Today’s deep learning models face an increasing demand to handle dynamic shape tensors and computation whose shape information remains unknown at compile time and varies in a nearly infinite range at runtime. This shape dynamism brings tremendous challenges for existing compilation pipelines designed for static models which optimize tensor programs relying on exact shape values. This paper presents TSCompiler, an end-to-end compilation framework for dynamic shape models. TSCompiler first proposes a symbolic shape propagation algorithm to recover symbolic shape information at compile time to enable subsequent optimizations. TSCompiler then partitions the shape-annotated computation graph into multiple subgraphs and fine-tunes the backbone operators from the subgraph within a hardware-aligned search space to find a collection of high-performance schedules. TSCompiler can propagate the explored backbone schedule to other fusion groups within the same subgraph to generate a set of parameterized tensor programs for fused cases based on dependence analysis. At runtime, TSCompiler utilizes an occupancy-targeted cost model to select from pre-compiled tensor programs for varied tensor shapes. Extensive evaluations show that TSCompiler can achieve state-of-the-art speedups for dynamic shape models. For example, we can improve kernel efficiency by up to 3.97× on NVIDIA RTX3090, and 10.30 × on NVIDIA A100 and achieve up to five orders of magnitude speedups on end-to-end latency.</p>","PeriodicalId":21618,"journal":{"name":"Science China Information Sciences","volume":"39 1","pages":""},"PeriodicalIF":8.8,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142252190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NeurDB: an AI-powered autonomous data system NeurDB：人工智能驱动的自主数据系统
IF 8.8 2区 计算机科学
Science China Information Sciences Pub Date : 2024-09-13 DOI: 10.1007/s11432-024-4125-9
Beng Chin Ooi, Shaofeng Cai, Gang Chen, Yanyan Shen, Kian-Lee Tan, Yuncheng Wu, Xiaokui Xiao, Naili Xing, Cong Yue, Lingze Zeng, Meihui Zhang, Zhanhao Zhao
{"title":"NeurDB: an AI-powered autonomous data system","authors":"Beng Chin Ooi, Shaofeng Cai, Gang Chen, Yanyan Shen, Kian-Lee Tan, Yuncheng Wu, Xiaokui Xiao, Naili Xing, Cong Yue, Lingze Zeng, Meihui Zhang, Zhanhao Zhao","doi":"10.1007/s11432-024-4125-9","DOIUrl":"https://doi.org/10.1007/s11432-024-4125-9","url":null,"abstract":"<p>In the wake of rapid advancements in artificial intelligence (AI), we stand on the brink of a transformative leap in data systems. The imminent fusion of AI and DB (AI×DB) promises a new generation of data systems, which will relieve the burden on end-users across all industry sectors by featuring AI-enhanced functionalities, such as personalized and automated in-database AI-powered analytics, and self-driving capabilities for improved system performance. In this paper, we explore the evolution of data systems with a focus on deepening the fusion of AI and DB. We present NeurDB, an AI-powered autonomous data system designed to fully embrace AI design in each major system component and provide in-database AI-powered analytics. We outline the conceptual and architectural overview of NeurDB, discuss its design choices and key components, and report its current development and future plan.</p>","PeriodicalId":21618,"journal":{"name":"Science China Information Sciences","volume":"6 1","pages":""},"PeriodicalIF":8.8,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142252191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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