Schweizer Archiv fur Tierheilkunde最新文献

{"title":"[Possible side effects of hormonal castration in a dog].","authors":"L V Kost, K J Rohner","doi":"10.17236/sat00454","DOIUrl":"https://doi.org/10.17236/sat00454","url":null,"abstract":"<p><strong>Introduction: </strong>A young, healthy male Labrador developed regurgitation, diarrhea, and decreased general condition after hormonal castration using a deslorelin implant (Suprelorin®) and concurrent cyproterone acetate injection. The gastrointestinal symptoms improved with symptomatic treatment, but lethargy persisted. The cause of the initial gastrointestinal symptoms is suspected to be impairment of the hypothalamic-pituitary-adrenal axis by the injected cyproterone acetate. Cyproterone acetate has a known glucocorticoid effect and inhibits the hypothalamic-pituitary-adrenal axis like other progestogens. Low-dose (0,1 mg/kg once daily) and high-dose (1 mg/kg once daily) prednisolone therapy led to a slight improvement in the general condition. Seven weeks after the cyproterone acetate injection, the dog was noticeably more active, but only after the surgical removal of the deslorelin implant did the owner considered the dog «back to his old self.« This suggests that the dog's reduced general condition was a side effect of the hormonal neutering. Twenty-one weeks after the deslorelin implant application and cyproterone acetate injection, and fourteen weeks after the last prednisolone administration, the adrenal glands responded normally in the ACTH stimulation test. One year later, the owner describes the dog as healthy without any gastrointestinal symptoms since then.</p>","PeriodicalId":21544,"journal":{"name":"Schweizer Archiv fur Tierheilkunde","volume":"167 5","pages":"301-308"},"PeriodicalIF":0.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Overview of known and new genetic defects and their prevalence in Swiss Fleckvieh cattle].","authors":"B A Weber, T Leuenberger, M Hauser, J C F Bousmar, C Gurtner, F R Seefried, C Drögemüller, J G P Jacinto","doi":"10.17236/sat00452","DOIUrl":"https://doi.org/10.17236/sat00452","url":null,"abstract":"<p><strong>Introduction: </strong>In the Swiss Fleckvieh (SF) cattle breed, derived from crosses between the Holstein (HO) and Simmental (SI) breeds, two inherited diseases, thrombocytopathy (TP) and bovine dilated cardiomyopathy (BDCMP), and four so-called fertility haplotypes, Fleckvieh haplotype 1,2,4,5 (FH1,2,4,5), have been described so far. In addition, the APOB-related hereditary disease cholesterol deficiency (CD) has been thoroughly described in the closely related HO breed after its discovery in 2015, but to date it has not been reported in the SF breed. The hereditary disease retinitis pigmentosa (RP), which leads to progressive retinal degeneration in homozygous carriers of a pathogenic variant of the RP1 gene, has been shown to occur in several European cattle breeds, but has not been described in the SF population. The aim of this study was to determine the prevalence of the known genetic defects and fertility haplotypes, as well as CD, in SF and the two closely related breeds, HO and SI. We also investigated the prevalence of RP in the SF population and characterised the genetic disease through a case series. To determine the prevalence, the SNP array genotyping data of over 65 000 cattle from the Swiss breeding association database were analyzed and based on those results, four RP1 homozygous animals were clinically evaluated. The allele frequency of the RP causing allele in SF was 13 % and the CD causing allele, previously described only in HO, was found in SF with an allele frequency of 1,17 %. The remaining six genetic defects occurred in SF either with a low allele frequency (TP 0,24 %, BDCMP 1,93 %, FH2 0,03 %, FH5 0,02 %) or not at all (FH1, FH4). The four RP1 homozygous animals with a mean age of 7,5 years old Showed varying degrees of visual impairment. Overall, the clinical and pathological findings were consistent with RP1-associated RP. In a suspected case, RP1 genotyping by genetic testing can confirm the diagnosis of RP. Due to the routine use of SNP genotyping to estimate breeding values, the genotypes of genetic defects are known, at least in the active breeding population, and can therefore be considered before matings. Avoiding risk mating will improve animal health and welfare and prevent animal losses, and therefore economic losses.</p>","PeriodicalId":21544,"journal":{"name":"Schweizer Archiv fur Tierheilkunde","volume":"167 5","pages":"280-291"},"PeriodicalIF":0.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Opportunistic Candida albicans infection with granulomatous meningoencephalitis and aggressive osteolysis.","authors":"A Siauciunaite, A Oevermann, K Beckmann, C Kümmerle-Fraune, S Meunier, O d'Anselme, M Waschk","doi":"10.17236/sat00453","DOIUrl":"https://doi.org/10.17236/sat00453","url":null,"abstract":"<p><strong>Introduction: </strong>Opportunistic Candida infection of the central nervous system is increasingly observed in immunocompromised humans and has recently been reported in three dogs. Calvarial bone lysis is a rare manifestation of chronic Candida infection in humans but has not been reported in dogs. This report describes the case of a 10-year-old immunocompromised Bullterrier dog with cerebral lesions associated with meningoencephalitis and multifocal aggressive bone lysis, destruction of turbinates and conchae, sinusitis, a nasopharyngeal mass, and regional lymphadenomegaly in MRI and CT. Histology and microbiological examinations revealed Candida albicans infection. The dog responded transiently to antifungal treatment but was euthanized due to clinical deterioration. Postmortem examination confirmed granulomatous fungal meningitis and multicentric T-cell lymphoma. This is the first report describing imaging features of an opportunistic Candida infection causing granulomatous meningoencephalitis in a dog. The dog in this case report showed aggressive bone lysis at the same location as granulomatous meningoencephalitis lesions, a rare feature of chronic Candida infection in humans.</p>","PeriodicalId":21544,"journal":{"name":"Schweizer Archiv fur Tierheilkunde","volume":"167 5","pages":"292-300"},"PeriodicalIF":0.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Udder morphology and milk yield of Lacaune dairy sheep.","authors":"P Makovicky, M Nagy","doi":"10.17236/sat00350","DOIUrl":"10.17236/sat00350","url":null,"abstract":"<p><strong>Introduction: </strong>This study analyses udder measurements in Lacaune ewes, with a particular focus on the effects of the control year (2022-2023) and lactation order on various udder traits. The number of Lacaune ewes included in the study ranged from 57 to 86 for various variables, while the number of control measurements was between 49 and 111. Significant year-on-year variations were observed in teat size and position, with teats generally decreasing in size with age. The control year had a significant impact on udder length, width, and depth, as well as teat length and angle. Our findings indicate that optimal teat angles for milking are around 45°. The order of lactation (parity) had a significant impact on udder size, particularly udder depth and length, which increased by the third lactation. The older ewes exhibited longer teats and a more horizontal teat position, indicative of larger udder cisterns. The results of the udder cistern measurements taken using different methods showed that cistern size tends to increase with age. It was found that larger cisterns correlate with higher milk yields and faster milk letdown. Although the impact of lactation order on cistern measurements was not statistically significant, the 'from the bottom' method proved more effective for assessing cistern size. There was considerable variation in the milkability parameters, including machine-milked and total milk yield. The correlation between udder attachment and milk production was significant, which highlights the importance of a strong udder attachment for efficient milk yield. A notable positive correlation between udder width and milk production indicates that wider udders yield more milk in shorter periods. The study findings indicate that larger udder cisterns, particularly on the left side, are associated with greater milk production. As ewes age and progress through lactations, udder morphology improves, facilitating better milkability. These findings provide a scientific basis for the use of specific udder traits in the selection of ewes with enhanced milk production potential for the Lacaune breed.</p>","PeriodicalId":21544,"journal":{"name":"Schweizer Archiv fur Tierheilkunde","volume":"25 1","pages":"225-238"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82822208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occlusion of a patent ductus arteriosus using an Amplatzer vascular plug II in a kitten.","authors":"M Baron Toaldo, N Schreiber","doi":"10.17236/sat00351","DOIUrl":"10.17236/sat00351","url":null,"abstract":"<p><strong>Introduction: </strong>A five-month-old kitten has been admitted to catheter assisted intravascular occlusion of a patent ductus arteriosus (PDA). Considering the small size of the patient, and of the femoral artery, a transvenous approach through the femoral vein was attempted. The PDA could be successfully occluded using an embolization device called Amplatzer vascular plug II. This device can be deployed retrogradely through the venous system, using a catheter, that must be passed through the caudal vena cava, right atrium and ventricle, and pulmonary artery, reaching the PDA. The intervention was assisted by fluoroscopic and transesophageal echocardiographic guidance. The cat recovered uneventfully from the procedure, and it was discharged the following day. Transvenous embolization of PDA can be successfully performed also in small patients or animals with comparably small peripheral arteries, like cats.</p>","PeriodicalId":21544,"journal":{"name":"Schweizer Archiv fur Tierheilkunde","volume":"135 1","pages":"240-244"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77295649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Work design approach to reduce stressors in small veterinary practices].","authors":"C Herren, O J Glardon, K Wolff","doi":"10.17236/sat00349","DOIUrl":"10.17236/sat00349","url":null,"abstract":"<p><strong>Introduction: </strong>Given the increasing shortage of skilled workers, working conditions in the veterinary sector are of central importance for the motivation and satisfaction of employees. Solutions to reduce stressors are important to keep skilled workers in their jobs in the long term and to counteract migration out of clinical work. An innovative approach to work design was developed as part of a master's thesis. The thesis was based on qualitative studies and structured according to defined characteristics, which can help to reduce stressors in small veterinary practices. The study aimed to develop an understanding of specific challenges in veterinary practices, as comparable research literature for the veterinary sector in Switzerland is limited. The theoretical basis of the work was based on findings from the human healthcare sector, which has similar problems. The qualitative data was collected through seven guided expert interviews, the transcripts were analyzed using Mayring's method. The resulting recommendation of this study can serve as a guideline for veterinary practices and aim to improve working conditions promoting employee satisfaction. The results not only contribute to the theoretical foundation in the area of work design, but also provide concrete impulses for small veterinary practices to increase their attractiveness and employee satisfaction.</p>","PeriodicalId":21544,"journal":{"name":"Schweizer Archiv fur Tierheilkunde","volume":"62 1","pages":"184-191"},"PeriodicalIF":0.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90223816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Influence of agents for permanent drinking water disinfection on the fermentation performance of rumen microorganisms in ruminants].","authors":"A Stettler, B Berchtold, S Probst","doi":"10.17236/sat00347","DOIUrl":"10.17236/sat00347","url":null,"abstract":"<p><strong>Introduction: </strong>Good quality drinking water and adequate water intake is essential in ensuring the health of livestock. Various factors can cause the formation of a biofilm in water pipes that acts as a reservoir for many different pathogens. The addition of disinfection agents, such as chlorine dioxide or peracetic acid, is proven to improve the quality of permanent drinking water. To date this method has primarily been used in pig and poultry housing, however, it is increasingly under discussion for use in cattle husbandry. As the effects of disinfectants in drinking water on rumen fermentation are not yet known, we performed a digestibility test using the Hohenheim Feed Value Test to determine the in vitro digestibility of organic matter (IVOMD). The influence of five different concentrations of chlorine dioxide and peracetic acid disinfectants on the IVOMD of hay and wheat were tested and rumen bacteria were counted under a microscope. The use of chlorine dioxide showed no major changes in the IVOMD of hay and wheat. At the recommended concentration of 0.5 mg/l, the IVOMD relative to the control was 97,1 % for hay and 102,7 % for wheat. The number of rumen bacteria was not affected by the use of chlorine dioxide. Conversely, the use of peracetic acid led to a significant reduction in rumen fermentation. At the recommended concentration of 15-25 mg/l (dosed at 15 mg/l and 25 mg/l), the IVOMD relative to the control was 38,2 % and 38,4 % for hay and 50,4 % and 22,4 % for wheat. The number of rumen bacteria also decreased significantly. Chlorine dioxide seemed to have little to no disinfection effect on in vitro ruminal fermentation, however, the exact mechanisms could not be determined in the present study. This trial shows that disinfectants for permanent drinking water disinfection in cattle farming should be used with caution. In particular, disinfection agents containing peracetic acid may impair fermentation of rumen microbes. Further research is required to determine if the results of the present in vitro study are transferable to practice.</p>","PeriodicalId":21544,"journal":{"name":"Schweizer Archiv fur Tierheilkunde","volume":"35 1","pages":"166-173"},"PeriodicalIF":0.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80173205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Temporal development of hypoxia markers in brachycephalic and -mesocephalic dogs after short physical exercise].","authors":"D A Koch, J Wenk, S Michel","doi":"10.17236/sat00348","DOIUrl":"10.17236/sat00348","url":null,"abstract":"<p><strong>Introduction: </strong>To objectify the oxygen debt in dogs with brachycephalic upper respiratory syndrome, eight mesocephalic dogs were subjected to a short running test on four test days and eight brachycephalic dogs on one test day. Blood samples were taken before and immediately after exercise and after 2 and 4 hours to assess cellular oxygenation. For this purpose, two available hypoxia markers, vascular endothelial growth factor (VEGF) and erythropoietin (EPO), were measured. The repeatability of the measurements was checked in the mesocephalic dogs. While VEGF measurement was repeatable over the 4 days of measurement, the EPO measurement was not. The VEGF basal values of the mesocephalic and brachycephalic dogs did not differ (7.6 ± 4.4 pg/ml and 6.9 ± 4.0 pg/ml, respectively). The measurement 4 hours after the running test showed significant differences. The VEGF value in the mesocephalic dogs increased by 42 % to 10.8 ± 4.7 pg/ml, while in the brachycephalic dogs it increased by 220 % to 22.1 ± 15.3 pg/ml. The EPO measurements showed a significant difference between the mesocephalic and brachycephalic dogs at all blood collection times; The basal value in mesocephalic dogs was approx. three times higher than in brachycephalic dogs (30.1 ± 22.6 mU/ml or 11.4 ± 3.5 mU/ml). However, the difference was not significant due to the large scatter in the mesocephalic dogs (p > 0.05). In contrast to the VEGF value, the EPO value did not change over the measurement period. The study shows that the presented method can be used together with the VEGF value for scientific and breeding purposes.</p>","PeriodicalId":21544,"journal":{"name":"Schweizer Archiv fur Tierheilkunde","volume":"98 1","pages":"175-183"},"PeriodicalIF":0.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75507275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Genetic defects in Braunvieh cattle of Switzerland - an overview].","authors":"S Glatthard, F R Seefried, A Gentile, J P G Jacinto, C Drögemüller","doi":"10.17236/sat00344","DOIUrl":"10.17236/sat00344","url":null,"abstract":"<p><strong>Introduction: </strong>Since 2010, genomic selection in Swiss cattle breeding has led to significant progress in the two local Braunvieh populations, Brown Swiss and Original Braunvieh. However, it has also contributed to further inbreeding, leading to an increased risk of outbreaks of monogenic recessive defects. Some long-known inherited diseases such as arachnomelia, spinal muscular atrophy, spinal dysmyelination, Weaver syndrome and renal dysplasia are now of little clinical importance, while new haplotypes and gene variants associated with reproductive disorders have recently been described. These include so-called fertility haplotypes and genetic diseases that rarely or never occur homozygous because the affected animals die shortly after birth or early in pregnancy. This work provides an overview of the known recessive genetic defects in Swiss Braunvieh cattle. Data from 56, 000 Swiss breeding cattle on 12 genetic defects show that known inherited diseases in Braunvieh only occur very sporadically (defect allele frequency < 1 %). Only the recently described achromatopsia (Original Braunvieh haplotype 1) has a relevant defect allele frequency of over 7 % and should be taken into account for mating plans in order to avoid calves with day blindness. In addition, the Braunvieh haplotypes 6 and 14 and the Original Braunvieh haplotypes 4 and 9 occur between 2-6 % and the mating of heterozygous carriers should be avoided in order to avoid homozygous offsprings that are presumably not embryonically viable. The further spread of known genetic defects can be prevented through comprehensive genotyping of the breeding populations and the careful selection of breeding animals, recently also with the help of digital apps for mating planning. Thus, genetically caused reproductive losses or the number of affected animals can be reduced, animal health and welfare can be sustainably improved through selective breeding.</p>","PeriodicalId":21544,"journal":{"name":"Schweizer Archiv fur Tierheilkunde","volume":"167 2","pages":"98-108"},"PeriodicalIF":0.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143410157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Evaluation of different cross-matching techniques in comparison to the tube agglutination method in dogs].","authors":"L Herter, C Weingart, N Merten, N Bock, B Kohn","doi":"10.17236/sat00345","DOIUrl":"10.17236/sat00345","url":null,"abstract":"<p><strong>Introduction: </strong>Cross-matching is used to determine the serological compatibility of donor and recipient blood. This procedure is used to detect possible antibodies against the donor's erythrocytes, thereby reducing the risk of immunological transfusion reactions. Various methods are available for cross-matching: In addition to the tube agglutination method, which is often viewed as a reference method, gel and immunochromatographic methods are available. In this study, a gel tube method, an antiglobulin-enhanced gel tube method, and an immunochromatographic method were evaluated in comparison to the tube agglutination method in 28 different major cross-matches. The evaluation resulted in 85,7 % agreement between the antiglobulin-enhanced gel tube method, in 60,7 % agreement between the gel tube method and in 35,7 % agreement between the immunochromatographic method and the tube agglutination method. Considering the macroscopically positive test results alone, the agreement between the tube agglutination method and the antiglobulin-enhanced gel tube method was 100 %, the gel tube method 62,5 % and with the immunochromatographic 0 %. Using the antiglobulin-enhanced gel tube method, 4/9 weakly positive cross-matches, which were positive with a microscopic degree of agglutination of 1+ - 2+ using the tube agglutination method, were compatible. In all other cross-matches with a higher degree of agglutination, the results were consistent with those of the tube agglutination method. Transfusion of incompatible blood products may result in hemolytic transfusion reactions. However, the clinical relevance of microscopically weakly positive cross-matches is unclear. The application of the various test kits took significantly less time compared to the tube agglutination procedure. Due to the strong agreement and reduction in required time, the antiglobulin-enhanced gel tube method offers a good alternative to the reference method, especially in emergency situations. On the other hand, there was only a weak agreement between the gel tube and no agreement between the immunochromatographic method and the reference method.</p>","PeriodicalId":21544,"journal":{"name":"Schweizer Archiv fur Tierheilkunde","volume":"167 2","pages":"109-119"},"PeriodicalIF":0.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143410156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}