[巨食道测试对白瑞士牧羊犬有效吗?]

IF 0.8 4区 农林科学 Q3 VETERINARY SCIENCES
A Kehl, C Schelling
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引用次数: 0

摘要

基因测试在控制单基因疾病方面发挥着重要作用,因为它们揭示了每只被测试狗的基因型,从而允许选择遗传负担较低的动物。对于一些复杂的遗传疾病和异常,可以进行所谓的风险测试,这可能有助于选择繁殖动物。他们分析了导致携带者患上疾病或异常的更高风险的dna序列变异。在密切相关的白瑞士牧羊犬品种中分析了德国牧羊犬先天性特发性巨食道风险测试(CIM-test)的有效性。结果清楚地表明,该品种的cim测试几乎没有信息,选择可能不会降低患病率,而只会降低遗传变异性。饲养者和饲主应该得到相应的通知。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Is the megaesophagus test valid for White Swiss Shepherds (Berger Blanc Suisse)?]

Introduction: Gene tests play an important role for controlling monogenetic diseases because they reveal a genotype for each tested dog and thereby allow for the selection of animals with a lower genetic burden. For some complex inherited diseases and anomalies so called risk-tests are available and may support the selection of breeding animals. They analyze DNA-sequence variants which render a higher risk for carriers to develop a disease or anomaly. The usefulness of a risk-test for congenital idiopathic megaoesophagus (CIM-test) in German shepherds was analyzed in the closely related breed of White Swiss shepherds. The results showed clearly that the CIM-test in this breed is almost not informative, and a selection would probably not reduce the prevalence but only lower the genetic variability. Breeders and owners should be informed accordingly.

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来源期刊
Schweizer Archiv fur Tierheilkunde
Schweizer Archiv fur Tierheilkunde 农林科学-兽医学
CiteScore
1.50
自引率
14.30%
发文量
46
审稿时长
18-36 weeks
期刊介绍: Das Schweizer Archiv für Tierheilkunde ist die älteste veterinärmedizinische Zeitschrift der Welt (gegründet 1816). Es ist das wissenschaftliche und praxisbezogene offizielle Publikationsorgan der Gesellschaft Schweizer Tierärztinnen und Tierärzte.
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