Saudi Journal of Anaesthesia最新文献_第4页

Propofol-Fentanyl versus propofol-ketamine sedation in gastrointestinal endoscopy: A systematic review and meta-analysis. 异丙酚-芬太尼与异丙酚-氯胺酮在胃肠道内窥镜中的镇静作用：一项系统综述和荟萃分析。

IF 1.3

Saudi Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-16 DOI: 10.4103/sja.sja_588_24

Elliott N Rees, Lucy Ms Hoade, Luke Mattey

{"title":"Propofol-Fentanyl versus propofol-ketamine sedation in gastrointestinal endoscopy: A systematic review and meta-analysis.","authors":"Elliott N Rees, Lucy Ms Hoade, Luke Mattey","doi":"10.4103/sja.sja_588_24","DOIUrl":"10.4103/sja.sja_588_24","url":null,"abstract":"Background: The optimal procedural sedation and analgesic regime for gastrointestinal endoscopy is uncertain. Ketamine and fentanyl are commonly used analgesic agents alongside propofol but both have significant side effect profiles.Objectives: This systematic review and meta-analysis compares the efficacy and safety of propofol-ketamine (PK) to propofol-fentanyl (PF) sedation for patients undergoing gastrointestinal endoscopy.Methods: Medline, EMBASE, and CENTRAL were searched to identify all comparative studies comparing PF to PK sedation. Nine randomized control trials (RCTs) met inclusion criteria. The primary outcomes were procedure time and recovery time. Secondary outcomes included adverse effects. All outcome data analyses were conducted using random-effects modeling.Findings: Nine RCTs with a total of 1006 patients were analyzed (508 (50.5%) PF, 498 PK). Sedation-analgesia regimes with PF were associated with both shorter procedure times (mean difference (MD) = -1.670 minutes (95% CI, -2.890, -0.450); P < 0.01) and recovery times (MD = -1.215 minutes (95% CI,-2.131, -0.300)) compared with PK. In the PF group, there was a higher incidence of desaturation (PF: 18.03% vs PK: 7.84%, OR = 3.163 (95% CI, 1.552, 6.444); P < 0.01) and hypotension (PF: 17.20% vs PK: 8.33%, OR = 2.501 (95% CI, 1.296, 4.824); P < 0.01).Conclusions: There is moderate certainty evidence that PF reduces procedure time and low certainty that it improves recovery time compared to PK for gastrointestinal endoscopy. The risk of potentially life-threatening hypotension and desaturation was significantly greater in the PF group.","PeriodicalId":21533,"journal":{"name":"Saudi Journal of Anaesthesia","volume":"19 3","pages":"292-302"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful management of a pediatric cardiac patient with Bombay blood group and leukocyte adhesion deficiency type II: A case report and literature review. 1例孟买血型及II型白细胞黏附不足小儿心脏病患者的成功治疗：1例报告及文献复习。

IF 1.3

Saudi Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-16 DOI: 10.4103/sja.sja_605_24

Ahmad Abuzaid, Ahmed Abdalwahab

{"title":"Successful management of a pediatric cardiac patient with Bombay blood group and leukocyte adhesion deficiency type II: A case report and literature review.","authors":"Ahmad Abuzaid, Ahmed Abdalwahab","doi":"10.4103/sja.sja_605_24","DOIUrl":"10.4103/sja.sja_605_24","url":null,"abstract":"Bombay blood group is a rare blood phenotype, frequently misinterpreted as \"O\" blood group, and sometime causes severe hemolytic transfusion reactions. We are reporting a 4-year-old cardiac patient with congenital heart disease. During routine intraoperative evaluation, the patient was confirmed as having Bombay blood group and leukocyte adhesion deficiency type II. As this condition is extremely rare in Saudi Arabia, matched blood donors were secured from outside the country. The patient underwent bilateral peripheral artery stenosis reconstruction. Successful intraoperative management was done using one unit of matched blood transfusion, acute normovolemic hemodilution strategy, intravenous injection of antifibrinolytic agents, and regular antimicrobial surgical prophylaxis. The postoperative period was uneventful, and the patient was discharged from the hospital 1 week later. Correct and preoperative identification of Bombay phenotype, patient labeling and flagging, maintaining records for rare blood groups, and collaborations with other blood banks are necessary strategies for safe management of patients with Bombay blood group.","PeriodicalId":21533,"journal":{"name":"Saudi Journal of Anaesthesia","volume":"19 3","pages":"413-415"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Suzetrigine (VX-548): Bidding goodbye to opioids: The latest oral non-opioid analgesic for acute pain. suzetriine (VX-548)：告别阿片类药物：最新的急性疼痛口服非阿片类镇痛药。

IF 1.3

Saudi Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-16 DOI: 10.4103/sja.sja_366_25

Konica Chittoria, Ankur Sharma, Nikhil Kothari, Kamlesh Kumari

引用次数: 0

Evaluating the efficacy of serratus posterior superior ıntercostal plane block as an optimal technique in breast cancer surgery: A case series. 评价后上锯肌ıntercostal平面阻滞作为乳腺癌手术最佳技术的疗效：一个病例系列。

IF 1.3

Saudi Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-16 DOI: 10.4103/sja.sja_592_24

Mihrican Sayan, Ozan Sayan, Mesut Erbas

引用次数: 0

Monitoring nociception in patients with morbid obesity undergoing bariatric surgery. 在接受减肥手术的病态肥胖患者中监测伤害感受。

IF 1.3

Saudi Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-16 DOI: 10.4103/sja.sja_661_24

Salvatore Fabrizio Favitta, Danilo Santolamazza, Ersilia Luca, Roberto De Cicco, Paola Aceto

{"title":"Monitoring nociception in patients with morbid obesity undergoing bariatric surgery.","authors":"Salvatore Fabrizio Favitta, Danilo Santolamazza, Ersilia Luca, Roberto De Cicco, Paola Aceto","doi":"10.4103/sja.sja_661_24","DOIUrl":"10.4103/sja.sja_661_24","url":null,"abstract":"Bariatric surgery is a rapidly developing field and presents a challenge for anesthesia management, especially in the treatment of acute postoperative pain. Severely obese patients have a greater risk of intra and postoperative complications due to their cardiovascular and respiratory pathophysiological alterations. Excessive fat also alters the normal metabolism of analgesic drugs, in particular opioids, thus reducing their therapeutic range and increasing the risk of reaching toxic doses with accumulation and overdose effects. Nociception, in contrast to pain, is not a subjective experience but a physiological response to a nociceptive stimulus, which manifests as objective modifications in vital parameters. An increasing number of monitoring methods have been approved in recent years, especially developed for the detection of intraoperative nociception to enable better control of opioid titration. This review aimed to provide an overview of the main monitoring systems commercially available devices, which could be used to monitor nociception during bariatric surgery. Eighteen studies evaluating the most widespread nociception monitoring systems were analyzed. These studies were mostly conducted on patients undergoing abdominal laparoscopic surgery, which is comparable to bariatric surgery in terms of pain stimulation. Intraoperative and postoperative opioid consumption were compared between patients subject to nociceptive monitoring and those in whom analgesia was guided by their changes in vital parameters. Although the devices seem able to optimize the anesthetic management of these patients, studies on bariatric populations are scarce and do not allow us to state whether the routine use of these tools can modify the patient's clinical outcome.","PeriodicalId":21533,"journal":{"name":"Saudi Journal of Anaesthesia","volume":"19 3","pages":"368-374"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nerve block or fascial block: This is the question. 神经阻滞还是筋膜阻滞：这是个问题。

IF 1.3

Saudi Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-16 DOI: 10.4103/sja.sja_682_24

Pierfrancesco Fusco, Gian Marco Petroni, Francesca De Sanctis, Chiara Maggiani, Emanuele Nazzarro

引用次数: 0

Anesthetic challenges in a pregnant patient with Von Hippel-Lindau disease: A case report. 妊娠冯希佩尔-林道病患者的麻醉挑战：1例报告。

IF 1.3

Saudi Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-16 DOI: 10.4103/sja.sja_839_24

Francisco Machado, Henrique Gouveia, Sara Freitas, Filipa Rodrigues

引用次数: 0

Breathing new life: Cutting-edge anesthetic strategies for whole lung lavage in pulmonary alveolar proteinosis. 呼吸新生命：肺泡蛋白沉积症全肺灌洗的尖端麻醉策略。

IF 1.3

Saudi Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-16 DOI: 10.4103/sja.sja_375_24

Anita Chouhan, Simran Kaur, Manoj Kamal, Nishant Kumar Chauhan, Alok Kumar Sharma, Goverdhan Dutt Puri

{"title":"Breathing new life: Cutting-edge anesthetic strategies for whole lung lavage in pulmonary alveolar proteinosis.","authors":"Anita Chouhan, Simran Kaur, Manoj Kamal, Nishant Kumar Chauhan, Alok Kumar Sharma, Goverdhan Dutt Puri","doi":"10.4103/sja.sja_375_24","DOIUrl":"10.4103/sja.sja_375_24","url":null,"abstract":"Pulmonary Alveolar Proteinosis (PAP) is a rare condition where surfactant accumulates in the lungs' alveoli, causing respiratory failure. Whole lung lavage (WLL) is the primary treatment, requiring careful perioperative management due to potential complications. We present the case of a 38-year-old man with severe PAP who underwent WLL with cardiopulmonary bypass standby. Preoperative assessment revealed severe hypoxemia and respiratory alkalosis. During surgery, he experienced desaturation and hemodynamic instability, necessitating noradrenaline support and real-time lung ultrasound monitoring. Postoperatively, significant improvements in oxygen levels and radiographic findings were observed. Diagnosis relies on Broncho alveolar lavage fluid analysis, and WLL is effective for patients with impaired gas exchange, improving symptoms and survival. This case highlights the importance of multidisciplinary care and meticulous perioperative management in achieving positive outcomes in PAP treatment with WLL.","PeriodicalId":21533,"journal":{"name":"Saudi Journal of Anaesthesia","volume":"19 3","pages":"400-402"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on: "Modified lumbar-sacral erector spinae plane block for the treatment of low back pain". 点评：“改良腰骶直肌脊柱平面阻滞治疗腰痛”。

IF 1.3

Saudi Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-16 DOI: 10.4103/sja.sja_21_25

Pranjali Kurhekar, Raghuraman M Sethuraman

引用次数: 0

Suprainguinal fascia iliaca block combined with a sacral erector spinae plane (S-ESP) block is a valid alternative for hip fracture surgery in frail patients. 腹股沟上筋膜髂阻滞联合骶竖棘平面（S-ESP）阻滞是治疗体弱患者髋部骨折手术的有效选择。

IF 1.3

Saudi Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-16 DOI: 10.4103/sja.sja_813_24

Marco Giudice, Riccardo Pulitanò, Francesca La Verde

引用次数: 0