suzetriine (VX-548):告别阿片类药物:最新的急性疼痛口服非阿片类镇痛药。

IF 1.4 Q3 ANESTHESIOLOGY
Saudi Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-16 DOI:10.4103/sja.sja_366_25
Konica Chittoria, Ankur Sharma, Nikhil Kothari, Kamlesh Kumari
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引用次数: 0

摘要

Suzetrigine是fda批准的第一个也是唯一一个用于治疗中度至重度急性疼痛的非阿片类口服药物。它通过提供良好的缓解而没有与阿片类药物使用相关的危险,代表了疼痛治疗向前迈出的重要一步。它的批准改变了术后疼痛护理,满足了关键的公共卫生需求,同时降低了对成瘾的担忧。虽然其不良反应需要进一步的研究,但其独特的机制和安全性在镇痛领域具有改变游戏规则的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Suzetrigine (VX-548): Bidding goodbye to opioids: The latest oral non-opioid analgesic for acute pain.

Suzetrigine is the first and only FDA-approved non-opioid oral medication designed to be used for the treatment of moderate-to-severe acute pain. It represents a significant step forward in pain treatment by providing excellent relief without the hazards associated with opiate usage. Its approval transforms postoperative pain care, meeting a key public health need while lowering addiction concerns. While the adverse effect profile requires additional investigation, its distinctive mechanism and safety feature represent a game-changing potential in the area of analgesia.

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来源期刊
CiteScore
1.90
自引率
8.30%
发文量
141
审稿时长
36 weeks
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