Yahui Liu, Jie Du, Yang Li, Qingxuan Zhang, Pu Li, Sha Li, Xiao Ma, Fupeng Xu
{"title":"A randomized controlled clinical trial to investigate the efficacy and safety of dexmedetomidine in treating postoperative acute pain.","authors":"Yahui Liu, Jie Du, Yang Li, Qingxuan Zhang, Pu Li, Sha Li, Xiao Ma, Fupeng Xu","doi":"10.4103/sja.sja_511_24","DOIUrl":"10.4103/sja.sja_511_24","url":null,"abstract":"<p><strong>Background: </strong>This study aims to investigate the efficacy and safety of dexmedetomidine in treating postoperative acute pain through a clinical randomized controlled trial.</p><p><strong>Methods: </strong>This study selected 165 patients who underwent general anesthesia surgeries at our hospital from October 2022 to May 2023 as research subjects. They were enrolled and randomly allocated to a control group (<i>n</i> = 73) and an experimental group (<i>n</i> = 74) based on a computer-generated random numbers table. Firstly, we compared the general clinical data before surgery. Secondly, we compared the pain degree, sedative degree, and vital signs at 6 time points (before surgery [T0], 1 h postoperatively [T1], 6 h postoperatively [T2], 12 h postoperatively [T3], 24 h postoperatively [T4], and 48 h postoperatively [T5]). Lastly, we compared the incidence of adverse reactions and comprehensive satisfaction degree for the two groups of patients after surgery.</p><p><strong>Results: </strong>The results showed that compared to the control group, the experimental group had lower VAS score, Ramsay score, mean arterial pressure (MAP), heart rate (HR), systolic blood pressure (SBP), and diastolic blood pressure (DBP) (<i>P</i> < 0.05), whereas blood oxygen saturation (SpO<sub>2</sub>) showed no change (<i>P</i> > 0.05). No difference was observed in the incidence of adverse reactions between the experimental and control groups (<i>P</i> > 0.05). The comprehensive satisfaction degree of patients in the experimental group was higher compared to the control group (<i>P</i> < 0.05).</p><p><strong>Conclusions: </strong>Dexmedetomidine could effectively manage the vital signs of patients with postoperative acute pain, improve treatment outcomes, alleviate pain, enhance sedation, ensure safety, and enhance comprehensive satisfaction.</p>","PeriodicalId":21533,"journal":{"name":"Saudi Journal of Anaesthesia","volume":"19 3","pages":"318-326"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240532/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anesthetic management challenges in a pediatric patient with Ellis Van Creveld syndrome and complex cardiac anomalies: A case report.","authors":"Madan Mohan Maddali, Mohammed Al Ghafri","doi":"10.4103/sja.sja_485_24","DOIUrl":"10.4103/sja.sja_485_24","url":null,"abstract":"<p><p>The case report discusses the anesthetic management and postoperative course of a 4-month-old girl with Ellis Van Creveld syndrome. Key challenges included an abnormal chest wall, tracheal abnormalities, and complex cardiac issues, requiring tailored anesthetic planning and vigilant monitoring. The patient experienced complications such as complete heart block and persistent hypercapnia after the surgery, which required a permanent pacemaker and prolonged noninvasive ventilation, leading to an extended hospital stay.</p>","PeriodicalId":21533,"journal":{"name":"Saudi Journal of Anaesthesia","volume":"19 3","pages":"395-399"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240526/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Robvis Shiny App: A tool for risk of bias assessment.","authors":"Nitinkumar Borkar, Abhijit Nair, Shilpa Meshram","doi":"10.4103/sja.sja_840_24","DOIUrl":"10.4103/sja.sja_840_24","url":null,"abstract":"","PeriodicalId":21533,"journal":{"name":"Saudi Journal of Anaesthesia","volume":"19 3","pages":"451-453"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240505/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Team-based learning versus traditional lectures in local anesthesia course: A cross-sectional study exploring dental students' perception and performance.","authors":"Salah Sakka","doi":"10.4103/sja.sja_582_24","DOIUrl":"10.4103/sja.sja_582_24","url":null,"abstract":"<p><strong>Background: </strong>Team-based learning (TBL) as a student-centered approach can be encouraged and supported by transforming the conventional lecture format into an engaging and active process of learning. The objective of this study was to explore students' perception of team-based learning and compare their performance after TBL sessions and traditional lectures in the local anesthesia course.</p><p><strong>Materials and methods: </strong>Eight topics of local anesthesia during the academic years 2022-2023 and 2023-2024 were divided into team-based learning sessions and traditional lectures. Teaching activities in TBL included tests and group discussions. A cross-sectional descriptive questionnaire comprising 10 written questions targeting students' perception of TBL and traditional lectures was handed to students at the end of the course.</p><p><strong>Results: </strong>The mean average scores of responses agreed with the related questions' statements. The results of Pearson's correlation test revealed that there was a significant relationship (<i>r</i> = 0.780, <i>P</i> < 0.05) between the statements of teaching methods and student's responses in both academic years.</p><p><strong>Conclusion: </strong>Students performed better and had positive opinions of TBL as their preferred learning technique when team-based learning substituted some didactic lectures.</p>","PeriodicalId":21533,"journal":{"name":"Saudi Journal of Anaesthesia","volume":"19 3","pages":"266-270"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tao Ma, Long Feng, Guan-Hua Li, Xiu-Yan Sun, Yang Chu, Wen-Hui Zhao, Shuai Feng, Hao Zhang, Wei Wang
{"title":"The impact of 24-hour sleep deprivation on cognition and inflammatory response in anesthesiologists and nurses in operating rooms.","authors":"Tao Ma, Long Feng, Guan-Hua Li, Xiu-Yan Sun, Yang Chu, Wen-Hui Zhao, Shuai Feng, Hao Zhang, Wei Wang","doi":"10.4103/sja.sja_772_24","DOIUrl":"10.4103/sja.sja_772_24","url":null,"abstract":"<p><strong>Introduction: </strong>The effects of acute sleep deprivation on cognitive function and inflammatory responses remain inadequately defined. This study aimed to evaluate changes in cognitive function and inflammatory responses among anesthesiologists and nurses in the operating room following 24-hour shift work-induced sleep deprivation.</p><p><strong>Material and methods: </strong>Forty anesthesiologists and nurses were assigned to either the sleep deprivation group (n = 20, working from 8:00 AM to 8:00 AM the following day) or the rest control group (n = 20, working regular hours from 8:00 AM to 5:00 PM). All participants underwent assessments of cognitive functions and peripheral blood sample collections for brain-derived neurotrophic factor (BDNF), tumor necrosis factor-alpha (TNF-α), and interleukin-1 beta (IL-1β) at 8:00 AM, 4:00 PM, 0:00, and 8:00 AM the following day. Cognitive functions were assessed using the Trail Making Test and the Stroop Color-Word Test.</p><p><strong>Results: </strong>Cognitive assessments revealed no significant effect on reaction time following one night of sleep deprivation (<i>P</i> > 0.05 for all). However, the learning effect from repeated administrations of the Trail Making Test and the Stroop Color-Word Test did not result in decreased reaction times in the sleep deprivation group (<i>P</i> > 0.05 for all). Increased fluctuations in serum levels of TNF-α and BDNF were observed after 24-hour shift work at 8:00 AM (<i>P</i> < 0.05 for all).</p><p><strong>Conclusion: </strong>Sleep deprivation induced by 24-hour shifts did not impair cognitive performance but did affect learning ability in anesthesiologists and nurses. Additionally, sleep deprivation caused increased fluctuations in serum levels of TNF-α and BDNF at 8:00 AM.</p>","PeriodicalId":21533,"journal":{"name":"Saudi Journal of Anaesthesia","volume":"19 3","pages":"353-362"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Riccardo Pulitanò, Flavia Bracci, Francesca La Verde, Marco Giudice
{"title":"When the FICC-PORT is (maybe) the first option: A case report.","authors":"Riccardo Pulitanò, Flavia Bracci, Francesca La Verde, Marco Giudice","doi":"10.4103/sja.sja_832_24","DOIUrl":"10.4103/sja.sja_832_24","url":null,"abstract":"<p><p>Ports are totally implanted intravenous devices used to administer intravenous therapies that require the central venous pathway. Traditionally, ports are implanted mostly on the chest wall or on the arms (PICC PORTs). In some patients, CHEST PORTs and PICC PORTs are contraindicated, and ports are implanted by inserting the catheter into the femoral vein (FEMORAL PORT or FICC PORT). In this report, we want to describe an unusual case of placement of a FICC-PORT using the most recent techniques of implantation and tip location.</p>","PeriodicalId":21533,"journal":{"name":"Saudi Journal of Anaesthesia","volume":"19 3","pages":"440-442"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240488/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Regional anesthesia for hip surgery: A review of current approaches and their application to clinical practice.","authors":"Tiberio Evangelista, Camilla Pugno, Simone Finazzi, Alessandro Colombi, Dario Bugada","doi":"10.4103/sja.sja_68_25","DOIUrl":"https://doi.org/10.4103/sja.sja_68_25","url":null,"abstract":"<p><p>Hip surgery is extremely common and ranges from surgery for hip fracture to elective procedures in younger adults. Pain can mark the postoperative period and compromise functional recovery. Nevertheless, major comorbidities may occur in the perioperative period, especially in elderly fragile patients. The approach to patients undergoing hip surgery has significantly evolved, focusing on multimodal strategies to optimize pain control while minimizing side effects, prompting patients' recovery. The seek for motor-sparing, analgesic techniques with a better risk benefit profile has promoted the application of new peripheral nerve blocks, with special attention paid to the newest fascial plane blocks. However, significant interest is addressed toward other outcomes (such major comorbidities and deaths) that may influence intermediate and long-term recovery. Specific strategies have been investigated to improve outcomes after hip surgery in elderly patients, considering the higher risk for complications, including delirium. In this narrative review, we aim to summarize the role of regional anesthesia and analgesia in the context of hip surgery by detailing on the effects of regional anesthesia on major outcomes. Considering the specific innervation of hip joint, we summarize the available evidence on newer peripheral nerve blocks for hip patients by focusing on potential complications associated with each technique, especially the occurrence of motor block. In this review, we aim to provide an updated and concise overview of the available evidence to help the reader planning the most appropriate strategy for hip surgery.</p>","PeriodicalId":21533,"journal":{"name":"Saudi Journal of Anaesthesia","volume":"19 2","pages":"164-173"},"PeriodicalIF":1.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12007850/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Huiying Hu, Zisu Luo, Bixi Li, Tingting Wang, Tanguan Wu, Bin Li, Xiaoyang Song
{"title":"Effect of ultrasound-guided PecS II block on the incidence of chronic postmastectomy pain in patients after radical mastectomy: A randomized controlled trial.","authors":"Huiying Hu, Zisu Luo, Bixi Li, Tingting Wang, Tanguan Wu, Bin Li, Xiaoyang Song","doi":"10.4103/sja.sja_398_24","DOIUrl":"https://doi.org/10.4103/sja.sja_398_24","url":null,"abstract":"<p><strong>Background: </strong>The pectoral nerve (PecS) II block is a recently introduced technique utilized for surgical anesthesia and postoperative analgesia during breast surgery. This study aims to investigate the impact of ultrasound-guided PecS II block on the incidence of chronic postmastectomy pain in patients following radical mastectomy.</p><p><strong>Methods: </strong>Ninety-eight patients undergoing selective radical mastectomy were included in this study. Based on whether the ultrasound-guided PecS II block was performed, the patients were randomly divided into the PecS II block group (group P) and the control group (group C). The primary outcomes included the incidence of chronic pain at 12 weeks after surgery, and the secondary outcomes included intraoperative dosage of remifentanil, the amount of oxycodone used in 48 h after surgery, time for the first analgesia administration, postoperative acute pain score 48 h after surgery, and HADS score at 48 h and 12 weeks after surgery. The presence or absence of pain in the previous week was recorded every 7 days after surgery (beginning on the 8<sup>th</sup> day after surgery). The postoperative pain duration curves of the two groups were plotted and compared by Kaplan-Meier estimation and log-rank test.</p><p><strong>Results: </strong>Compared with group C, the incidence of chronic pain in group P at 12 weeks after surgery was significantly decreased by 14.13% (20.65% vs. 34.78%, <i>P</i> < 0.05). The amount of remifentanil used in group P was significantly reduced (1.46 ± 0.11 mg vs. 2.66 ± 0.18 mg, <i>P</i> < 0.001), and the amount of oxycodone used 48 h after surgery in group P was remarkably reduced than that in group C (22.57 ± 3.21 mg vs. 31.62 ± 4.71 mg, <i>P</i> < 0.001). The first analgesic requirement time of group P was significantly longer than that of group C (368.80 ± 157.68 min vs. 96.60 ± 40.12 min, <i>P</i> < 0.001). Compared with group C, the postoperative acute pain score 48 h after surgery and the HADS score 48 h and 12 weeks after surgery in group P were significantly decreased (<i>P</i> < 0.05). The postoperative pain duration curve of the two groups was significantly different (<i>P</i> < 0.05), and the postoperative pain duration of group P was lower than that of group C (<i>P</i> < 0.05).</p><p><strong>Conclusions: </strong>PecS II block can reduce the incidence of chronic postmastectomy pain after radical mastectomy, reduce perioperative opioid consumption, provide better analgesia, and improve the degree of anxiety and depression of patients.</p><p><strong>Trial registration: </strong>ChiCTR2200066968, 22/12/2022.</p>","PeriodicalId":21533,"journal":{"name":"Saudi Journal of Anaesthesia","volume":"19 2","pages":"235-242"},"PeriodicalIF":1.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12007852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advancing regional anesthesia - Innovations, insights, and impact on patient care.","authors":"Alessandro De Cassai, Abdelazeem Eldawlatly","doi":"10.4103/sja.sja_140_25","DOIUrl":"https://doi.org/10.4103/sja.sja_140_25","url":null,"abstract":"","PeriodicalId":21533,"journal":{"name":"Saudi Journal of Anaesthesia","volume":"19 2","pages":"163"},"PeriodicalIF":1.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12007857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143980274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fascial plane blocks in pediatric anesthesia: A narrative review.","authors":"Nur N Yucal, Can Aksu","doi":"10.4103/sja.sja_146_25","DOIUrl":"https://doi.org/10.4103/sja.sja_146_25","url":null,"abstract":"<p><p>Regional anesthesia techniques have become a cornerstone of pain management in the adult population, providing adequate analgesia while minimizing systemic side effects. Despite the numerous benefits demonstrated in pediatric studies, the implementation of regional anesthesia in children remains insufficiently adopted in clinical settings. One primary concern preventing broader application is the potential for complications of these techniques in pediatric patients, which understandably raises apprehension among clinicians. However, the introduction of fascial plane blocks in the literature has led to a significant advancement in this field. These regional anesthesia techniques are increasingly being incorporated into routine clinical practice, as they are relatively easy to learn and apply and safe techniques. Fascial plane blocks provide adequate pain management while minimizing opioid consumption, which not only helps reduce the risk of opioid-related side effects but also contributes to a more comfortable perioperative and postoperative experience for young patients. These blocks can significantly enhance patient recovery and satisfaction by facilitating analgesia. This narrative review briefly summarizes different indications of fascial plane blocks and their effectiveness in managing pain among pediatric patients, illuminating critical points to consider when applying these techniques.</p>","PeriodicalId":21533,"journal":{"name":"Saudi Journal of Anaesthesia","volume":"19 2","pages":"190-197"},"PeriodicalIF":1.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12007847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}