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Scandinavian journal of respiratory diseases最新文献

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Immunoprofile studies in patients with pulmonary tuberculosis. II. Correlation of levels of different classes of immunoglobulins and specific antibodies with the extent of tuberculosis. 肺结核患者的免疫谱研究。2不同种类的免疫球蛋白和特异性抗体水平与结核程度的相关性。
Scandinavian journal of respiratory diseases Pub Date : 1979-08-01
J Skvor, L Trnka, Z Kugukovová
{"title":"Immunoprofile studies in patients with pulmonary tuberculosis. II. Correlation of levels of different classes of immunoglobulins and specific antibodies with the extent of tuberculosis.","authors":"J Skvor,&nbsp;L Trnka,&nbsp;Z Kugukovová","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Humoral immune response of patients with newly detected, bacteriologically confirmed pulmonary tuberculosis was determined prior to initiation of chemotherapy. Correlation with the extent of the disease was studied. A significant rise in the IgA and IgG levels in the serum was observed, the increase in the IgA levels correlated with the extent of the disease. In tuberculous patients elevated levels of anti-OT (ppd) antibodies were found by haemaggluination, but no marked correlation was observed with the extent of the disease. There was no interrelationship between the IgA or IgG increase and that of specific anti-OT (PPD) antibodies. The importance of the mentioned findings is discussed.</p>","PeriodicalId":21508,"journal":{"name":"Scandinavian journal of respiratory diseases","volume":"60 4","pages":"168-71"},"PeriodicalIF":0.0,"publicationDate":"1979-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11339241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lung cancer. Treatment and early results. 肺癌。治疗和早期结果。
Scandinavian journal of respiratory diseases Pub Date : 1979-08-01
H Rostad, J R Vale
{"title":"Lung cancer. Treatment and early results.","authors":"H Rostad,&nbsp;J R Vale","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Of 1053 patients with primary cancer of the lung, 549 (52%) underwent thoracotomy and 40% a presumably radical resection. Lobectomies were performed in 227 patients (41% of those operated), pneumonectomy in 160 (29%). Early mortality (death within 30 days) was 5.5% with the highest figure (11%) after pneumonectomy, 5% after explorative thoracotomy and 3% after lobectomy. Cardiorespiratory failure and myocardial infarction occurred in 19 (3.5%) of the operated cases and were responsible for 14 early deaths. Bronchopleural fistula developed in 11 patients. Of 874 morphologically classified tumours, squamous cell composed 45%, undifferentiated large cell 17%, small cell anaplastic 14%, adenocarcinoma 19%, carcinoid 2% and others 3%. Of 21 tumours typed as small cell anasplastic prior to therapy, six were differently classified at the later (postoperative/postmortal) stage.</p>","PeriodicalId":21508,"journal":{"name":"Scandinavian journal of respiratory diseases","volume":"60 4","pages":"191-6"},"PeriodicalIF":0.0,"publicationDate":"1979-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11735113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunoprofile studies in patients with pulmonary tuberculosis. I. Correlation of pretherapy cellular tests with characteristics of the disease. 肺结核患者的免疫谱研究。1 .治疗前细胞试验与疾病特征的相关性。
Scandinavian journal of respiratory diseases Pub Date : 1979-08-01
J Skvor, L Trnka
{"title":"Immunoprofile studies in patients with pulmonary tuberculosis. I. Correlation of pretherapy cellular tests with characteristics of the disease.","authors":"J Skvor,&nbsp;L Trnka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cell immunity profiles were determined in 46 patients with previously untreated pulmonary tuberculosis, confirmed bacteriologically, and in 21 blood donors. Evaluations were made of T-lymphocytes, blastic transformation of lymphocytes after stimulation with phytohaemagglutinin or tuberculoprotein, and migration inhibition of blood leukocytes stimulated by tuberculo-protein. The average proportion of T-lymphocytes in the peripheral blood was significantly diminished in the group of tuberculous patients, and the intensity of the decline correlated both with age and extent of the disease. Similarly, migration of leukocytes in tuberculous patients was, in the presence of tuberculoprotein, markedly inhibited. The inhibition was correlated to the extent of the disease, expressed as the number of bacilli excreted. It can be concluded that, despite the depression of immunocompetent cells, active daughter clones under the influence of a specific antigen are capable of producing a factor conditioning migration inhibition.</p>","PeriodicalId":21508,"journal":{"name":"Scandinavian journal of respiratory diseases","volume":"60 4","pages":"161-7"},"PeriodicalIF":0.0,"publicationDate":"1979-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11602252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lung compliance and lung morphology following artificial ventilation in the premature and full-term rabbit neonate. 人工通气对兔早产儿和足月新生儿肺顺应性和肺形态的影响。
Scandinavian journal of respiratory diseases Pub Date : 1979-08-01
R Nilsson
{"title":"Lung compliance and lung morphology following artificial ventilation in the premature and full-term rabbit neonate.","authors":"R Nilsson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Rabbit neonates delivered on day 27--30 of gestation were subjected to intermittent positive pressure ventilation (IPPV) for 60 min. Tidal volume was standardized to 10 ml/kg, and the insufflation pressure required to maintain this tidal volume was recorded. The quasistatic compliance of the lung-thorax system, corrected for variations in body weight, was significantly lower in animals delivered on day 27--28 than in those delivered on day 29--30. Immature animals with low lung-thorax compliance (less than 0.40 ml/cm H2O.kg) regularly developed widespread necrosis of bronchiolar epithelium following IPPV, whereas no such lesions were observed in mature animals. It seems probable that these lesions are secondary to overdistension of bronchioles during IPPV and that this abnormal expansion pattern is related to a deficiency of surfactant in the lungs of immature newborn animals.</p>","PeriodicalId":21508,"journal":{"name":"Scandinavian journal of respiratory diseases","volume":"60 4","pages":"206-14"},"PeriodicalIF":0.0,"publicationDate":"1979-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11602253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corticosteroid therapy of pulmonary sarcoidosis. A prospective evaluation of alternate day and daily dosage in stage II disease. 肺结节病的皮质类固醇治疗。II期疾病隔日和每日剂量的前瞻性评价。
Scandinavian journal of respiratory diseases Pub Date : 1979-08-01
O Selroos, T L Sellergren
{"title":"Corticosteroid therapy of pulmonary sarcoidosis. A prospective evaluation of alternate day and daily dosage in stage II disease.","authors":"O Selroos,&nbsp;T L Sellergren","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Thirty-nine sarcoidosis patients with pulmonary infiltrations (stage II) of less than 5 years duration and not treated earlier with corticosteroids were randomly allocated for treatment with methylprednisolone for 7 months or for observation without therapy. Every other treated patient was given the drugs daily and every other followed an alternate-day regimen. After 7 months the chest radiographic finding, the forced vital capacity and the diffusion capacity for carbon monoxide were superior in the treated group. There was no difference between the two drug regimens. After 24 and 48 months no statistically significant differences between the untreated and the treated groups were found.</p>","PeriodicalId":21508,"journal":{"name":"Scandinavian journal of respiratory diseases","volume":"60 4","pages":"215-21"},"PeriodicalIF":0.0,"publicationDate":"1979-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11735115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunoprofile studies in patients with pulmonary tuberculosis. III. Study of haemolytic complement in serum and phagocytic activity of blood neutrophils. 肺结核患者的免疫谱研究。3血清溶血补体及嗜中性粒细胞吞噬活性的研究。
Scandinavian journal of respiratory diseases Pub Date : 1979-08-01
M Rieger, L Trnka, J Skvor, P Mison
{"title":"Immunoprofile studies in patients with pulmonary tuberculosis. III. Study of haemolytic complement in serum and phagocytic activity of blood neutrophils.","authors":"M Rieger,&nbsp;L Trnka,&nbsp;J Skvor,&nbsp;P Mison","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The total level of haemolytic complement in serum, and the phagocytic activity of blood neutrophils were found to be significantly increased in patients with active pulmonary tuberculosis prior to treatment. A relationship could not, however, be demonstrated between the elevation in the two studied values and the extent of tuberculous changes in the lungs of the patients.</p>","PeriodicalId":21508,"journal":{"name":"Scandinavian journal of respiratory diseases","volume":"60 4","pages":"172-5"},"PeriodicalIF":0.0,"publicationDate":"1979-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11735110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serological diagnosis of tuberculosis. Evaluation of two years' experience. 肺结核的血清学诊断。二年工作经验评估。
Scandinavian journal of respiratory diseases Pub Date : 1979-08-01
G W Bradley, A C Nicholls, L Banfield
{"title":"Serological diagnosis of tuberculosis. Evaluation of two years' experience.","authors":"G W Bradley,&nbsp;A C Nicholls,&nbsp;L Banfield","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Two years' experience of a simple serological test for the diagnosis of tuberculosis has been evaluated. This test fails to distinguish clearly between tuberculous and non-tuberculous patients. There is an unacceptably high incidence of false positive and false negative results, although the latter would be reduced by taking the highest titre values of several samples from one patient. Modification of the test to eliminate IgM agglutination produced a marked fall in false positive results. These preliminary results suggest that this modified test is more useful, in that a positive test is a strong indication of tuberculosis. The use of a Coombs' test to agglutinate incomplete complexes did not improve results.</p>","PeriodicalId":21508,"journal":{"name":"Scandinavian journal of respiratory diseases","volume":"60 4","pages":"176-83"},"PeriodicalIF":0.0,"publicationDate":"1979-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11735111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lung cancer. Symptoms, signs and diagnostic criteria. 肺癌。症状、体征和诊断标准。
Scandinavian journal of respiratory diseases Pub Date : 1979-08-01
H Rostad, J R Vale, I Nesthus
{"title":"Lung cancer. Symptoms, signs and diagnostic criteria.","authors":"H Rostad,&nbsp;J R Vale,&nbsp;I Nesthus","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A consecutive hospital series of 1 053 patients treated for lung cancer during the period 1962 through 1971 has been studied. Clinical symptoms were present more often in men than in women and in 42% symptoms had been noted more than 6 months prior to the diagnosis. Peripheral tumours gave less symptoms than central ones. Although in 22% of the patients the tumour was discovered on a chest film in the absence of relevant symptoms, 12% only had been detected by regular mass X-ray screening. More than 40% of the peripherally located tumours were clinically silent. Squamous cell and anaplastic small cell cancers were predominantly centrally located (80 and 90%, respectively) against 65% and 74% for adenocarcinomas and undifferentiated large cell tumours.</p>","PeriodicalId":21508,"journal":{"name":"Scandinavian journal of respiratory diseases","volume":"60 4","pages":"184-90"},"PeriodicalIF":0.0,"publicationDate":"1979-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11735112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of recurrent pleural effusion by pleurodesis with quinacrine. Comparison between instillation by repeated thoracenteses and by tube drainage. 奎宁治疗胸腔积液复发的疗效观察。反复胸腔灌注与管引流的比较。
Scandinavian journal of respiratory diseases Pub Date : 1979-08-01
G Stiksa, R Korsgaard, B G Simonsson
{"title":"Treatment of recurrent pleural effusion by pleurodesis with quinacrine. Comparison between instillation by repeated thoracenteses and by tube drainage.","authors":"G Stiksa,&nbsp;R Korsgaard,&nbsp;B G Simonsson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A total of 121 pleurodeses using instillations of quinacrine (mepacrine) in patients with recurrent pleural effusion were performed. All but three patients suffered from pleural malignancy. A comparison was made between the results achieved by repeated thoracenteses (73 cases) and by simultaneous tube drainage (48 cases). Tube drainage shortened the treatment and lowered the number of painful interventions. There was no difference in the quality of pleurodesis achieved by the two methods. The treatment failed in 12% of patients treated by repeated thoracenteses and in 14% of those treated by tube drainage. Patients with pleurodeses survive longer than non-treated subjects and have a considerably better quality of life.</p>","PeriodicalId":21508,"journal":{"name":"Scandinavian journal of respiratory diseases","volume":"60 4","pages":"197-205"},"PeriodicalIF":0.0,"publicationDate":"1979-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11735114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plasma concentrations of lidocaine during inhalation anaesthesia for fiberoptic bronchoscopy. 纤维支气管镜吸入麻醉时利多卡因的血药浓度。
Scandinavian journal of respiratory diseases Pub Date : 1979-06-01
N P Boye, J E Bredesen
{"title":"Plasma concentrations of lidocaine during inhalation anaesthesia for fiberoptic bronchoscopy.","authors":"N P Boye,&nbsp;J E Bredesen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The plasma concentration of lidocaine and its metabolite, mono-ethyl-glycine-xylidine, was measured furing fiberoptic bronchoscopy (FB) using an ultrasonic nebulizer to achieve topical anaesthesia. Most patients received additional anaesthesia of the laryngeal region and the tracheobronchial tree during the procedure. The achieved plasma concentrations showed that a substantial amount of lidocaine was absorbed, but toxic plasma levels were not reached. Lidocaine plasma concentration above the therapeutic range for treating cardiac diseases was observed in one patient. The use of an ultrasonic nebulizer with lidocaine before FB seems to give sufficient local anaesthesia and to be a safe method.</p>","PeriodicalId":21508,"journal":{"name":"Scandinavian journal of respiratory diseases","volume":"60 3","pages":"105-8"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11697677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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