{"title":"Allergic granulomatous angiitis.","authors":"F Veevaete, M van der Straeten, M de Vos, H Roels","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 15-year-old boy died after a 3 years' illness; asthmatic bronchitis, recurrent heart failure and eosinophilia were the essential manifestations. The autopsy elicited a diagnosis of allergic granulomatous angiitis, because of angiitis with fibrinoid necrosis and granulomatous lesions in vascular and extravascular regions. The most important differential diagnostic aspects of this disease are discussed, especially the resemblances to Wegener's granulomatosis, hypersensitivity angiitis and polyarteritis nodosa.</p>","PeriodicalId":21508,"journal":{"name":"Scandinavian journal of respiratory diseases","volume":"59 6","pages":"287-96"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11258261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Blood eosinophil leucocytes and eosinophil cationic protein. Diurnal variation in normal subjects and patients with bronchial asthma.","authors":"R Dahl, P Venge, I Olsson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Normal subjects and patients with bronchial asthma showed a similar diurnal variation in blood eosinophil count and serum eosinophil cationic protein concentration. The blood eosinophils showed the highest count during the night whereas serum eosinophil cationic protein showed the highest concentration in the early evening. It is concluded that this may result from a difference in hormonal or other influences.</p>","PeriodicalId":21508,"journal":{"name":"Scandinavian journal of respiratory diseases","volume":"59 6","pages":"323-5"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11775704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Long-term trial of an alpha adrenoceptor blocking drug (Indoramin) in asthma. A preliminary report.","authors":"J L Black, D M Temple, S D Anderson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Eight patients suffering from both asthma and migraine underwent a clinical trial for 3 months of indoramin, an alpha adrenoceptor antagonist with antihistamine and antiserotonin activity. Patients were told indoramin was prescribed for migraine prophylaxis. In three asthmatic patients there was a marked increase in airflow meter (AFM) readings which were recorded daily, the remaining five showing no significant change or a decrease in AFM readings. Indoramin did not appear to potentiate the action of the beta sympathomimetic aerosols. It is suggested that a small population of asthmatic patients may derive therapeutic benefit from an alpha adrenoceptor antagonist. Seven of the eight patients experienced a 50% decrease in the frequency of their migraine headaches.</p>","PeriodicalId":21508,"journal":{"name":"Scandinavian journal of respiratory diseases","volume":"59 6","pages":"307-12"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11582380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Blood eosinophil leucocyte and eosinophil cationic protein. In vivo study of the influence of beta-2-adrenergic drugs and steroid medication.","authors":"R Dahl, P Venge","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The in vivo effect of beta-2-adrenergic stimulating and blocking drugs and of corticosteroid medication on blood eosinophils and serum eosinophil cationic protein (S-ECP) has been studied. The beta-2-adrenergic drugs, salbutamol and terbutaline, had an eosinopenic effect. They were able to decrease S-ECP concentration, which administration of steroid was not, indicating that only the adrenergic stimulators affect leucocyte secretion. Care must be taken in interpretation of blood eosinophil count and S-ECP concentration, and the actual medical treatment must be known.</p>","PeriodicalId":21508,"journal":{"name":"Scandinavian journal of respiratory diseases","volume":"59 6","pages":"319-22"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11258262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prognosis of chronic obstructive lung disease in relation to radiology and electrocardiogram.","authors":"A Kok-Jensen, K Ebbehøj","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Survival in relation to radiological and electrocardiographical changes was examined in a retrospective study of 228 hospital patients aged 40-69 years with a FEV1 of 1.5 1 or less, and a FEV1 of 70% or less of the vital capacity due to chronic obstructive lung disease. The only radiological changes which influenced survival after 4 years were enlarged heart and pronounced dilatation of the pulmonary artery. Thirty-eight percent of the patients with normal ECG but with pronounced dilatation of the pulmonary artery were alive after 4 years. In patients with normal ECG and normal or moderate dilatation of the pulmonary artery about 80% had survived after 4 years. There was only 18% survival after 4 years in patients with abnormal ECG and pronounced dilatation of the pulmonary artery and/or with enlarged heart, and only 6% in patients from age group 60-69. In patients with abnormal ECG without enlarged heart and without pronounced dilatation of the pulmonary artery 50-63% had survived after 4 years. Pulmonary hyperinflation was not important for survival during the first 4 years.</p>","PeriodicalId":21508,"journal":{"name":"Scandinavian journal of respiratory diseases","volume":"58 6","pages":"304-10"},"PeriodicalIF":0.0,"publicationDate":"1977-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11364846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mepacrine hydrochloride in the treatment of malignant pleural effusion. A controlled randomized trial.","authors":"J Mejer, K M Mortensen, H H Hansen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of local instillation of mepacrine hydrochloride (quinacrine hydrochloride U.S.P., Atabrine) was compared with triethylenethiophosphoramide (Thiotepa) applied locally and with pleurocentesis alone. Twentyfive patients with disseminated malignant disease were allocated at random to one of these three treatments. A finding of more than 500 ml effusion within 3 months of instituting treatment was regarded as a failure, and subsequently one of the other treatments was used at random. Sixty-four per cent of the patients treated with mepacrine responded, compared with 27% treated with triethylenethiophosphoramide, and 11% treated with pleurocentesis alone.</p>","PeriodicalId":21508,"journal":{"name":"Scandinavian journal of respiratory diseases","volume":"58 6","pages":"319-23"},"PeriodicalIF":0.0,"publicationDate":"1977-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11622181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ventilatory lung function following two years of tobacco abstinence.","authors":"B Bake, H Oxhöj, R Sixt, L Wilhelmsen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Spirometry, maximal expiratory flows and the nitrogen closing volume test were studied in 59 subjects following their attempt to give up smoking. Seventeen subjects were tobacco abstinent for at least 5 months. This group showed significant improvement of vital capacity (VC), forced expiratory volume in 1 sec (FEV1) and the slope of phase III. Nine of these subjects remained ex-smokers for at least 24 months. However, no significant improvement of any of the measured variables could be established in this group. This may be due to the small number in the group and the circumstance that they were older and had worse lung function before smoking cessation compared with those who resumed smoking.</p>","PeriodicalId":21508,"journal":{"name":"Scandinavian journal of respiratory diseases","volume":"58 6","pages":"311-8"},"PeriodicalIF":0.0,"publicationDate":"1977-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11809879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Systemic hypertension, left ventricular hypertrophy and myocardial infarction in patients with chronic obstructive lung disease.","authors":"E Kassis","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Left ventricular function was evaluated prospectively during 1 year in a controlled clinical study of 73 patients with chronic obstructive lung disease. The control group comprised 68 patients matched for age and sex and with no evidence of airways obstruction. Left ventricular hypertrophy was found in 52% and systemic hypertension in 58% of patients in the study group compared with 6% and 15% respectively in the controls. Left ventricular hypertrophy was diagnosed in 70% of patients with chronic bronchitis and in 19% of those with chronic emphysema. Systemic hypertension was observed in 45% of the bronchitic type patients and in 81% of those with emphysema. The incidence of myocardial infarction in the study group was not lower than in the controls. The high frequency of left ventricular hypertrophy in patients with chronic obstructive lung disease can probably be related to a similar high frequency of systemic hypertension. Hypertension per se does not explain left ventricular hypertrophy in all patients with chronic bronchitis, but hypoxemia and acidosis seem to be of pathogenetic importance in these cases.</p>","PeriodicalId":21508,"journal":{"name":"Scandinavian journal of respiratory diseases","volume":"58 6","pages":"324-9"},"PeriodicalIF":0.0,"publicationDate":"1977-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11364848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A new ear oximeter for assessment of exercise-induced arterial desaturation in patients with pulmonary diseases.","authors":"H Poppius, A A Viljanen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Changes in arterial oxygen saturation during exercise were measured with a new eight-wavelength ear oximeter and calculated from blood gas measurements on simultaneously drawn arterial blood samples from 48 patients with pulmonary diseases. When the calculated oxygen saturation during exercise was more than 80% there change in oxygen saturation (SEE 1.0%). This non-invasive, simple and rapid method seems to be clinically useful for detecting the development of significant arterial hypoxaemia during exercise in patients with pulmonary diseases.</p>","PeriodicalId":21508,"journal":{"name":"Scandinavian journal of respiratory diseases","volume":"58 5","pages":"279-83"},"PeriodicalIF":0.0,"publicationDate":"1977-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11804270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}