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Relationship between age and cellular suppressive activity in resistance to Histoplasma capsulatum infection. 抗荚膜组织浆体感染细胞抑制活性与年龄的关系。
Sabouraudia Pub Date : 1985-10-01
M R Reyes Montes, J Casasola, N E Elizondo, M L Taylor
{"title":"Relationship between age and cellular suppressive activity in resistance to Histoplasma capsulatum infection.","authors":"M R Reyes Montes,&nbsp;J Casasola,&nbsp;N E Elizondo,&nbsp;M L Taylor","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>One-month-old and 1-year-old male BALB/c mice showed a lower resistance than 4.5-month-old mice to Histoplasma capsulatum infection. 4.5-month-old mice successfully resolved the infection when challenged with either a LD50 or LD100 for 1-month-old mice. A critical clinical course of experimental histoplasmosis was observed in 4.5-month-old syngeneic mice when spleen cells from 1-month-old BALB/c mice were transferred to them. Irradiated recipient mice, into which bone marrow and spleen cells were transferred, died when infected with the LD100 for 1-month-old mice. The same occurred with 4.5-month-old non-irradiated infected mice which received only spleen cells and with 1-month-old mice which were used as a control of infection. However, infected and non-transferred 4.5-month-old mice survived this dose. Thus, the adoptive transference of spleen cells from 1-month-old mice to 4.5-month-old mice suppressed the resistance of these adult mice to infection. Apparently, the transference of the suppressive state requires the presence of two cell populations, a non-adherent and an adherent and radioresistant cell present in the spleen of male 1-month-old mice.</p>","PeriodicalId":21469,"journal":{"name":"Sabouraudia","volume":"23 5","pages":"351-60"},"PeriodicalIF":0.0,"publicationDate":"1985-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15021681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Scedosporium (Monosporium) apiospermum: multiple brain abscesses. 尖孢子虫:多发性脑脓肿。
Sabouraudia Pub Date : 1985-10-01 DOI: 10.1080/00362178585380531
M Gari, J Fruit, P Rousseaux, J M Garnier, C Trichet, J C Baudrillart, P Comte, P Feucheres, J M Pinon
{"title":"Scedosporium (Monosporium) apiospermum: multiple brain abscesses.","authors":"M Gari,&nbsp;J Fruit,&nbsp;P Rousseaux,&nbsp;J M Garnier,&nbsp;C Trichet,&nbsp;J C Baudrillart,&nbsp;P Comte,&nbsp;P Feucheres,&nbsp;J M Pinon","doi":"10.1080/00362178585380531","DOIUrl":"https://doi.org/10.1080/00362178585380531","url":null,"abstract":"<p><p>A 32-year-old female with alcoholic cirrhosis attempted to drown herself in a pond. She remained in a coma for 57 days. After a stormy course she developed multiple brain abscesses due to Scedosporium (Monosporium) apiospermum. Despite intravenous and intrathecal amphotericin B (total dose 870 mg) the patient died 71 days after the near drowning.</p>","PeriodicalId":21469,"journal":{"name":"Sabouraudia","volume":"23 5","pages":"371-6"},"PeriodicalIF":0.0,"publicationDate":"1985-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/00362178585380531","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15183170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 31
In-vitro killing of Candida species by murine immunoeffectors and its relationship to the experimental pathogenicity. 小鼠免疫效应剂体外杀灭念珠菌及其与实验致病性的关系。
Sabouraudia Pub Date : 1985-10-01 DOI: 10.1080/00362178585380541
A Vecchiarelli, F Bistoni, E Cenci, S Perito, A Cassone
{"title":"In-vitro killing of Candida species by murine immunoeffectors and its relationship to the experimental pathogenicity.","authors":"A Vecchiarelli,&nbsp;F Bistoni,&nbsp;E Cenci,&nbsp;S Perito,&nbsp;A Cassone","doi":"10.1080/00362178585380541","DOIUrl":"https://doi.org/10.1080/00362178585380541","url":null,"abstract":"<p><p>Killing of yeast cells of several species of Candida by murine phagocytic cells was assessed in vitro by a radiolabel release microassay and measurement of colony forming units. The most effective candidacidal phagocytes, i.e. polymorphonuclear and bone marrow cells, were able to kill equally well cells of any species or isolate tested, given sufficient time (4 h) and an appropriate effector: target ratio. However, C. guilliermondii, C. krusei and C. parapsilosis were killed by polymorphonuclear and bone marrow cells much more promptly (1 h) and at a significantly lower effector:target ratio than C. albicans, C. tropicalis and C. viswanathii. Moreover, there were immune effectors such as peritoneal resident macrophages and, mostly, spleen cells which were practically ineffective against C. albicans and C. tropicalis but showed significant activity against C. guilliermondii, C. krusei and C. parapsilosis, even in mice immuno-depressed with cyclophosphamide. Three isolates of C. albicans, differing in the capacity to form germ tubes, also differed in mouse virulence: the germ-tube forming isolate was the most virulent. However, they showed an identical pattern of susceptibility to killing by mouse immunoeffectors, suggesting that virulence is probably not due to the resistance of hyphal cell to phagocytosis.</p>","PeriodicalId":21469,"journal":{"name":"Sabouraudia","volume":"23 5","pages":"377-87"},"PeriodicalIF":0.0,"publicationDate":"1985-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/00362178585380541","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15022399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 41
The ecology of Paracoccidioides brasiliensis: a puzzle still unsolved. 巴西副球虫的生态学:一个尚未解决的谜题。
Sabouraudia Pub Date : 1985-10-01
A Restrepo
{"title":"The ecology of Paracoccidioides brasiliensis: a puzzle still unsolved.","authors":"A Restrepo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Some aspects pertaining to the ecology of the dimorphic fungus, Paracoccidioides brasiliensis, are reviewed. The available facts concerning the interactions among the only known host (man), the environment (limited to certain Latin-American countries) and the parasite (with an unknown habitat), are analysed. Efforts are made to detect clue circumstances which may lead to discovery of the fungus micro-niche. An analysis of P. brasiliensis mycelial form reveals that such a form has the required capabilities to be the natural infectious form. Its requirements for a moist environment in vitro as well as the high relative humidity predominating in the heart of the endemic areas point towards the possibility of an aquatic--or at least, an extremely humid--habitat for P. brasiliensis.</p>","PeriodicalId":21469,"journal":{"name":"Sabouraudia","volume":"23 5","pages":"323-34"},"PeriodicalIF":0.0,"publicationDate":"1985-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15021680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The ecology of Paracoccidioides brasiliensis: a puzzle still unsolved. 巴西副球虫的生态学:一个尚未解决的谜题。
Sabouraudia Pub Date : 1985-09-01 DOI: 10.1080/00362178585380481
Angela Restrepo M
{"title":"The ecology of Paracoccidioides brasiliensis: a puzzle still unsolved.","authors":"Angela Restrepo M","doi":"10.1080/00362178585380481","DOIUrl":"https://doi.org/10.1080/00362178585380481","url":null,"abstract":"Some aspects pertaining to the ecology of the dimorphic fungus, Paracoccidioides brasiliensis, are reviewed. The available facts concerning the interactions among the only known host (man), the environment (limited to certain Latin-American countries) and the parasite (with an unknown habitat), are analysed. Efforts are made to detect clue circumstances which may lead to discovery of the fungus micro-niche. An analysis of P. brasiliensis mycelial form reveals that such a form has the required capabilities to be the natural infectious form. Its requirements for a moist environment in vitro as well as the high relative humidity predominating in the heart of the endemic areas point towards the possibility of an aquatic--or at least, an extremely humid--habitat for P. brasiliensis.","PeriodicalId":21469,"journal":{"name":"Sabouraudia","volume":"77 1","pages":"323-34"},"PeriodicalIF":0.0,"publicationDate":"1985-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83880666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 304
A comparison between Dactylaria gallopava and Scolecobasidium humicola: first report of an infection in a tortoise caused by S. humicola. 龟头革螨与龟头革螨的比较:龟头革螨引起的陆龟感染的首次报道。
Sabouraudia Pub Date : 1985-08-01
I Weitzman, S A Rosenthal, J L Shupack
{"title":"A comparison between Dactylaria gallopava and Scolecobasidium humicola: first report of an infection in a tortoise caused by S. humicola.","authors":"I Weitzman,&nbsp;S A Rosenthal,&nbsp;J L Shupack","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Scolecobasidium humicola, a soil fungus and etiologic agent of phaeohyphomycosis in fish, is herein reported to cause cutaneous lesions in a tortoise, Terrapine carolina var. carolina. S. humicola was isolated from lesions on the foot and dematiaceous hyphae were observed in KOH preparations of the biopsy and in stained preparations. This isolate and others were compared morphologically and physiologically with isolates of Dactylaria gallopava which it resembles. As a result of this investigation, we concluded that D. gallopava may be differentiated from S. humicola macroscopically, by the production in D. gallopava of an extensive diffusible purplish-red to reddish-brown pigment when cultured on Sabouraud dextrose agar; microscopically, by the presence and usually predominance of conidia, whose apical cell is markedly wider than the basal cell, and usually constricted at the septum; and physiologically, by the ability to grow on media containing cycloheximide and by the ability to grow well at 36-45 degrees C. In contrast, S. humicola does not usually produce a diffusible pigment on Sabouraud's dextrose agar or if present, is not extensive; it lacks the wider upper cell; is less constricted or non-constricted at the central septum; grows on media containing cycloheximide, although some inhibition may occur and lastly, does not grow at 36 degrees C or higher. Both species were urease positive, hydrolysed tyrosine but not casein, xanthine, or gelatin.</p>","PeriodicalId":21469,"journal":{"name":"Sabouraudia","volume":"23 4","pages":"287-93"},"PeriodicalIF":0.0,"publicationDate":"1985-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15160831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A novel method for estimating killing ability and digestion of Paracoccidioides brasiliensis by phagocytic cells in vitro. 一种估算巴西副球虫体外吞噬能力和消化能力的新方法。
Sabouraudia Pub Date : 1985-08-01
M Goihman-Yahr, A Rothenberg, R Rosquete, E Avila-Millán, M C de Albornoz, M H de Gómez, B San Martín, A Ocanto, J Pereira, T Molina
{"title":"A novel method for estimating killing ability and digestion of Paracoccidioides brasiliensis by phagocytic cells in vitro.","authors":"M Goihman-Yahr,&nbsp;A Rothenberg,&nbsp;R Rosquete,&nbsp;E Avila-Millán,&nbsp;M C de Albornoz,&nbsp;M H de Gómez,&nbsp;B San Martín,&nbsp;A Ocanto,&nbsp;J Pereira,&nbsp;T Molina","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We describe a novel method by which phagocytosis, digestion and killing of Paracoccidioides brasiliensis yeast cells by polymorphonuclear leukocytes or other phagocytic cells may be estimated simultaneously. Suspensions of P. brasiliensis (yeast-like phase) were sonicated, counted and incubated at 37 degrees C with known numbers of phagocytes. Control preparations contained no phagocytic cells. At given intervals samples were incorporated into gelatin nutrient medium and droplets of the mixtures were incubated at room temperature. Live yeast-like P. brasiliensis germinate in vitro and produce filaments. After incubation, droplets may be melted and examined under phase contrast optics, or the cells may be washed and stained by a variation of Papanicolaou's method. Digested P. brasiliensis, intact but non-germinating yeasts and filamented (viable) yeasts may be identified and counted. Killing and digestive abilities of phagocytes may be estimated by the difference between values obtained from phagocyte-containing and control preparations.</p>","PeriodicalId":21469,"journal":{"name":"Sabouraudia","volume":"23 4","pages":"245-51"},"PeriodicalIF":0.0,"publicationDate":"1985-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13562310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative electrophoresis, isoelectric focusing and numerical taxonomy of some isolates of Fonsecaea pedrosoi and allied fungi. 部分枫香菌及其亲缘真菌分离株的比较电泳、等电聚焦及数值分类。
Sabouraudia Pub Date : 1985-08-01 DOI: 10.1080/00362178585380381
O Ibrahim-Granet, C de Bievre, F Romain, S Letoffe
{"title":"Comparative electrophoresis, isoelectric focusing and numerical taxonomy of some isolates of Fonsecaea pedrosoi and allied fungi.","authors":"O Ibrahim-Granet,&nbsp;C de Bievre,&nbsp;F Romain,&nbsp;S Letoffe","doi":"10.1080/00362178585380381","DOIUrl":"https://doi.org/10.1080/00362178585380381","url":null,"abstract":"<p><p>The proteins in broken-cell extracts from eight isolates of Fonsecaea pedrosoi, the principal agent of chromomycosis, were studied and compared by electrophoresis and isoelectric focusing. A type pattern was established with 16 fractions ranging in molecular weight between 7600 and 78500 daltons and 16 fractions varying in isoelectric point between 4.95 and 7.90. A genetic distance of 0.1 found by the numerical study applied to both analyses reveals a considerable similarity among the isolates studied. This resemblance was moreover observed between F. pedrosoi and other related dematiaceous fungi.</p>","PeriodicalId":21469,"journal":{"name":"Sabouraudia","volume":"23 4","pages":"253-64"},"PeriodicalIF":0.0,"publicationDate":"1985-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/00362178585380381","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15160830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
Growth of Candida albicans in dexamethasone-supplemented media. 白色念珠菌在添加地塞米松培养基中的生长。
Sabouraudia Pub Date : 1985-08-01
M Ghannoum, G Burns, K Abu Elteen
{"title":"Growth of Candida albicans in dexamethasone-supplemented media.","authors":"M Ghannoum,&nbsp;G Burns,&nbsp;K Abu Elteen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Candida albicans grown in dexamethasone (DXM) shows an apparent increase in dry weight. This increase, however, represents an artefact due to entrapment and incorporation of DXM by the yeast. Thus opportunistic infections by C. albicans which are promoted by DXM must be due entirely to effects other than growth enhancement of the organism.</p>","PeriodicalId":21469,"journal":{"name":"Sabouraudia","volume":"23 4","pages":"313-5"},"PeriodicalIF":0.0,"publicationDate":"1985-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15015429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of various antibiotics on gastrointestinal colonization and dissemination by Candida albicans. 各种抗生素对白色念珠菌胃肠道定植和传播的影响。
Sabouraudia Pub Date : 1985-08-01 DOI: 10.1080/00362178585380391
M J Kennedy, P A Volz
{"title":"Effect of various antibiotics on gastrointestinal colonization and dissemination by Candida albicans.","authors":"M J Kennedy,&nbsp;P A Volz","doi":"10.1080/00362178585380391","DOIUrl":"https://doi.org/10.1080/00362178585380391","url":null,"abstract":"<p><p>Mice were treated orally with various antibiotics to determine which members of the indigenous intestinal microflora normally suppress Candida albicans colonization and dissemination from the gastrointestinal (GI) tract. The mice were given penicillin, clindamycin, vancomycin, erythromycin, or gentamicin for 3 days, and then challenged orally with C. albicans. Penicillin, clindamycin, and vancomycin, but not gentamicin or erythromycin, decreased the total anaerobic bacterial populations in the animals ceca, and increased the enteric bacilli population levels. All three of the former antibiotics allowed C. albicans to proliferate in the gut and, subsequently, disseminate from the GI tract to visceral organs. The ability of C. albicans to associate with intestinal mucosal surfaces was also tested. It was found that antibiotics which reduced anaerobic population levels, but not enteric bacilli or aerobes, also predisposed animals to mucosal association by C. albicans. It is suggested that the strictly anaerobic bacterial populations which predominate in the gut ecosystem are responsible for the inhibition of C. albicans adhesion, colonization and dissemination from the GI tract.</p>","PeriodicalId":21469,"journal":{"name":"Sabouraudia","volume":"23 4","pages":"265-73"},"PeriodicalIF":0.0,"publicationDate":"1985-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/00362178585380391","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15015426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 124
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