Romanian Journal of Internal Medicine最新文献_第8页

IF 1.9

Romanian Journal of Internal Medicine Pub Date : 2022-03-17 Print Date: 2022-03-01 DOI: 10.2478/rjim-2021-0032

Taro Horino, Masami Ogasawara, Takeshi Kashio, Satoshi Inotani, Masayuki Ishihara, Hiroshi Ohnishi, Masahiro Komori, Osamu Ichii, Yoshio Terada

{"title":"Lupus-related protein-losing enteropathy associated with pseudo-pseudo Meigs' syndrome and successfully treated with hydroxychloroquine.","authors":"Taro Horino, Masami Ogasawara, Takeshi Kashio, Satoshi Inotani, Masayuki Ishihara, Hiroshi Ohnishi, Masahiro Komori, Osamu Ichii, Yoshio Terada","doi":"10.2478/rjim-2021-0032","DOIUrl":"https://doi.org/10.2478/rjim-2021-0032","url":null,"abstract":"We herein report the first case of lupus-related protein-losing enteropathy associated with pseudo-pseudo Meigs' syndrome. Lupus-related protein-losing enteropathy and pseudo-pseudo Meigs' syndrome are extremely rare complications in patients with systemic lupus erythematosus, Both have a similar clinical course characterized by producing marked ascites, and respond to steroids in typical cases. However, in our case, steroid monotherapy was inadequate and the addition of hydroxychloroquine was effective for their treatment. Furthermore, no reports have previously confirmed elevated CA 125 levels with lupus-related protein-losing enteropathy or increased 99mTc-HSA activity with pseudo-pseudo Meigs' syndrome. In addition, we are the first to report an evaluation of the histopathology of lupus-related protein-losing enteropathy. Previously reported cases have been described as being caused by either pseudo-Meigs's syndrome or lupus-related protein-losing enteropathy as the cause of the rare pathology that causes marked pleural effusion and ascites in patients with systemic lupus erythematosus, but it has not been evaluated whether the other is co-occurring. Our case highlights that there is a potential case of overlapping lupus-related protein-losing enteropathy and pseudo-Pseudo-Meigs's syndrome. Furthermore, it is possible that patients with marked ascites with elevated CA 125 levels were mistakenly diagnosed with Meigs's syndrome or pseudo-Meigs's syndrome associated with malignant or benign ovarian tumors and underwent surgery. Clinicians should not forget SLE with pseudo-Pseudo-Meigs's syndrome as one of the differential diagnoses for marked ascites with elevated CA 125 levels.","PeriodicalId":21463,"journal":{"name":"Romanian Journal of Internal Medicine","volume":"60 1","pages":"85-89"},"PeriodicalIF":1.9,"publicationDate":"2022-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39271391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Anti-dense fine speckled (DFS) antibody: its staining pattern in indirect immunofluorescence and its clinical relevance. 抗致密细斑(DFS)抗体:间接免疫荧光染色模式及其临床意义。

IF 1.9

Romanian Journal of Internal Medicine Pub Date : 2022-03-17 Print Date: 2022-03-01 DOI: 10.2478/rjim-2021-0029

Samet Karahan, Şerife Emre, Hatice T Hörmet-Öz

{"title":"Anti-dense fine speckled (DFS) antibody: its staining pattern in indirect immunofluorescence and its clinical relevance.","authors":"Samet Karahan, Şerife Emre, Hatice T Hörmet-Öz","doi":"10.2478/rjim-2021-0029","DOIUrl":"https://doi.org/10.2478/rjim-2021-0029","url":null,"abstract":"Background: Dense fine speckled (DFS) pattern is defined by very intense, heterogeneous speckled staining of nucleoplasms of interphase HEp-2 cells and chromosomal areas of metaphase cells. The association of Anti-DFS70 and rheumatologic signs, symptoms, and diagnosis were evaluated.Methods: One-hundred-eight anti-DFS70 positives who got consecutively admitted to the Rheumatology clinic between January and June 2020 were analyzed. The clinical and laboratory findings of positives for anti-DFS70 antibody were compared with those with DFS pattern ANA IFA staining rates. Also, anti-DFS70 positivity rates and their correlation with the DFS staining pattern were analyzed retrospectively in 1016 CTD patients.Results: The most common complaint was joint pain seen in 77 (71.3%) and the most common laboratory abnormality was RF-positivity observed in 10/108 (9.3%) who had anti-DFS70 positivity. The most common ANA staining pattern was DFS (72/108; 66.7%); one-third had other than DFS. No statistical significance was found for the association of any of the rheumatological complaints and laboratory findings with the DFS staining pattern. ANA analysis was performed in a total of 964/1016 (94.88%) CTD patients and 44 (4.56%) of these positive for anti-DFS70. The correlation coefficient showed good correlations between the DFS pattern staining and anti-DFS70 antibody positivity (r=+0.773, p<0.001).Conclusions: Anti-DFS70-positives have a low rate of CTD. A low anti-DFS70 positivity rate was observed in patients with CTD. As such, it can be considered that anti-DFS70 does not predict CTD or even excludes it.","PeriodicalId":21463,"journal":{"name":"Romanian Journal of Internal Medicine","volume":"60 1","pages":"66-76"},"PeriodicalIF":1.9,"publicationDate":"2022-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39264379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Non-secretory myeloma in young man mimicking the Gorham disease: case report and the literature review. 模拟Gorham病的年轻人非分泌性骨髓瘤:病例报告及文献复习。

IF 1.9

Romanian Journal of Internal Medicine Pub Date : 2022-03-17 Print Date: 2022-03-01 DOI: 10.2478/rjim-2021-0036

Hanene Lassoued Ferjani, Moalla Mariem, Hassen Affess, Kaouther Maatallah, Dhia Kaffel, Mourad Jenzri, Wafa Hamdi

引用次数: 0

Characteristics and outcomes of patients with COVID-19 and liver injury: a retrospective analysis and a multicenter experience. COVID-19合并肝损伤患者的特征和结局:回顾性分析和多中心经验

IF 1.9

Romanian Journal of Internal Medicine Pub Date : 2022-03-17 Print Date: 2022-03-01 DOI: 10.2478/rjim-2021-0027

Andrei Voiosu, Adina Roman, Ruxandra Pop, Alina Boeriu, Cristiana Popp, Sabina Zurac, Theodor Voiosu, Daniela Dobru, Bogdan Mateescu

{"title":"Characteristics and outcomes of patients with COVID-19 and liver injury: a retrospective analysis and a multicenter experience.","authors":"Andrei Voiosu, Adina Roman, Ruxandra Pop, Alina Boeriu, Cristiana Popp, Sabina Zurac, Theodor Voiosu, Daniela Dobru, Bogdan Mateescu","doi":"10.2478/rjim-2021-0027","DOIUrl":"https://doi.org/10.2478/rjim-2021-0027","url":null,"abstract":"Background and aims. Patients with COVID-19 frequently present abnormal elevated liver function tests of unknown clinical significance. We aimed to investigate the characteristics and factors influencing outcome in patients with confirmed SARS-CoV-2 infection and liver injury on admission.Methods. This is a retrospective observational study of patients hospitalized in two COVID units in Romania. Relevant data on clinical and laboratory parameters and medication administered during the admission were analyzed to identify predictors of a negative outcome. Patients with confirmed COVID-19 and liver function tests (LFTs) above the upper limit of normal were included in the analysis.Results. From 1,207 patients, we identified 134 patients (11%) with abnormal LFTs during hospitalization. The majority of patients had mildly elevated levels and a predominantly cholestatic pattern of liver injury. Patients who received lopinavir/ritonavir were more likely to have increased ALAT levels (p<0.0001). Sixteen patients had pre-existing chronic liver disease, and they were more likely to suffer from severe COVID-19 (p=0.009) and have a negative outcome (p<0.001), but on multivariate analysis, only the severity of COVID-19 was predictive of death (OR 69.9; 95% CI 6.4-761.4).Conclusions. Mild liver injury is relatively common in COVID-19 and possibly influenced by medication. Patients with chronic liver disease are at high risk for negative outcome, but the severity of the infection is the only predictor of death.","PeriodicalId":21463,"journal":{"name":"Romanian Journal of Internal Medicine","volume":"60 1","pages":"49-55"},"PeriodicalIF":1.9,"publicationDate":"2022-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39177254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

The role of thyroid hormones in carotid arterial wall remodeling in women. 甲状腺激素在女性颈动脉壁重塑中的作用。

IF 1.9

Romanian Journal of Internal Medicine Pub Date : 2022-03-17 Print Date: 2022-03-01 DOI: 10.2478/rjim-2021-0028

Maida Seferovic Saric, Miljenka-Jelena Jurasic, Hrvoje Budincevic, Milan Milosevic, Bojana Kranjcec, Sanja Kovacic, Jana Leskovar, Vida Demarin

{"title":"The role of thyroid hormones in carotid arterial wall remodeling in women.","authors":"Maida Seferovic Saric, Miljenka-Jelena Jurasic, Hrvoje Budincevic, Milan Milosevic, Bojana Kranjcec, Sanja Kovacic, Jana Leskovar, Vida Demarin","doi":"10.2478/rjim-2021-0028","DOIUrl":"https://doi.org/10.2478/rjim-2021-0028","url":null,"abstract":"Introduction: Thyroid hormones affect the cardiovascular system, but the precise mechanisms of their effects on the development of atherosclerosis are not entirely clear. The relationship between subclinical hypothyroidism, dyslipidemia and carotid atherosclerosis has been widely investigated, but the findings were controversial. The aim of the present study was to determine whether female subjects with subclinical hypothyroidism (SHypo) have increased carotid intima-media thickness (IMT) compared with euthyroid subjects, as well as to examine the association of SHypo, carotid atherosclerosis and dyslipidemia.Methods: This research included 100 women aged 30 to 70 years who were divided into two groups: the SHypo group including subjects with signs of subclinical hypothyroidism and the control group of euthyroid subjects. Carotid IMT thickness using B mode ultrasound was determined and its correlation with serum concentrations of fT4, TSH, CRP, and lipid profile including small dense LDL (sdLDL) was analysed.Results: Subjects with SHypo had significantly increased carotid IMT (IMT ≥ 75th centile) in all three measured segments of the right (p <0.001) and the left (p = 0.001) carotid artery compared to the control group, with a significantly more frequent appearance of plaque (25% vs. 9%; p = 0.05). Significant positive correlations were found between higher TSH and higher IMT values. Increased age, LDL cholesterol, and TSH predicted thickening of the carotid artery IMT.Conclusions: It is important to screen people showing early, subclinical signs of thyroid gland dysfunction due to its impact on carotid atherosclerosis development.","PeriodicalId":21463,"journal":{"name":"Romanian Journal of Internal Medicine","volume":"60 1","pages":"24-33"},"PeriodicalIF":1.9,"publicationDate":"2022-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39217175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Association between admission blood glucose and prognosis in non-diabetic patients with first-ever acute myocardial infarction. 非糖尿病患者首次急性心肌梗死入院血糖与预后的关系

IF 1.9

Romanian Journal of Internal Medicine Pub Date : 2022-03-17 Print Date: 2022-03-01 DOI: 10.2478/rjim-2021-0033

Ramin Eskandari, Parisa Matini, Sepideh Emami, Yousef Rezaei

{"title":"Association between admission blood glucose and prognosis in non-diabetic patients with first-ever acute myocardial infarction.","authors":"Ramin Eskandari, Parisa Matini, Sepideh Emami, Yousef Rezaei","doi":"10.2478/rjim-2021-0033","DOIUrl":"https://doi.org/10.2478/rjim-2021-0033","url":null,"abstract":"Background: Admission hyperglycemia has been associated with major adverse cardiovascular and cerebrovascular events (MACCEs) in patients with acute coronary syndrome.Methods: In this study we sought to determine the association between admission blood sugar (ABS) and the outcomes of non-diabetic patients with first-ever acute myocardial infarction (MI). Non-diabetic patients with MI were evaluated from March 2016 to March 2019. Baseline characteristics, laboratories, electrocardiogram, and baseline left ventricular ejection fraction (LVEF) were recorded. All patients were followed up and outcomes were obtained. Follow-up data comprised of repeating electrocardiogram and echocardiography at 1 year, and MACCE, including re-MI, stroke, and mortality.Results: A total of 312 patients with a mean age of 54.2 ± 11.9 years were evaluated. All patients were followed up for a median of 38 months. The frequencies of in-hospital mortality and MACCE at late follow-up were higher in third tertile of ABS compared with those in first and second tertiles (both p <0.05). Based on the Cox regression analysis, the independent predictors of MACCE included age (hazard ratio [HR] 1.068, 95% confidence interval [CI] 1.033 - 1.105, p <0.001), third tertile of ABS >172 mg/dL (HR 21.257, 95% CI 2.832 - 159.577, p=0.003), and baseline LVEF (HR 0.947, 95% CI 0.901 - 0.995, p=0.031).Conclusion: Admission stress hyperglycemia is associated with increased rates of in-hospital mortality and MACCE at late follow-up in non-diabetic patients with MI. Moreover, elevated ABS, older ages, and a decreased value of baseline LVEF predicted MACCE during follow-up.","PeriodicalId":21463,"journal":{"name":"Romanian Journal of Internal Medicine","volume":"60 1","pages":"34-41"},"PeriodicalIF":1.9,"publicationDate":"2022-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39325276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Discontinuation of Eculizumab treatment after hematological remission in patients with atypical and drug-induced hemolytic uremic syndrome. 非典型和药物性溶血性尿毒症综合征患者血液学缓解后停用Eculizumab治疗。

IF 1.9

Romanian Journal of Internal Medicine Pub Date : 2022-03-17 Print Date: 2022-03-01 DOI: 10.2478/rjim-2021-0034

Hasan H Yeter, Ulver Derici, Turgay Arinsoy, Kadriye Altok, Yasemin Erten, Galip Guz

{"title":"Discontinuation of Eculizumab treatment after hematological remission in patients with atypical and drug-induced hemolytic uremic syndrome.","authors":"Hasan H Yeter, Ulver Derici, Turgay Arinsoy, Kadriye Altok, Yasemin Erten, Galip Guz","doi":"10.2478/rjim-2021-0034","DOIUrl":"https://doi.org/10.2478/rjim-2021-0034","url":null,"abstract":"Introduction. The aim was to evaluate the effect of therapeutic plasma exchange (TPE) and eculizumab on hematological and renal survival in atypical hemolytic uremic syndrome (aHUS), and additionally, to examine the reliability of discontinuation of eculizumab treatment.Methods. This was an observational and retrospective study of 18 patients diagnosed with aHUS.Results. The median age of the study population was 30 (22-66) years. Four of 18 patients achieved hematological remission with the TPE alone. However, one patient died after three sessions of TPE. Eculizumab was used in 13 patients and no death was observed. One year after treatment, improved kidney function was observed in 2 of 3 (66%) patients for TPE and 5 of 9 (56%) patients for Eculizumab. We discontinued eculizumab treatment in 9 patients. One of the patients who had a C3 gene mutation experienced disease relapse after Eculizumab discontinuation. None of the patients who had drug associated aHUS developed disease relapse after Eculizumab discontinuation.Conclusion. Eculizumab treatment is a life-saving therapy in aHUS. Treatment discontinuation may be considered at least six months after hematologic remission in patients who had stable renal function or no expectancy for renal survival. Moreover, drug-associated cases seem to tend not to develop disease relapse in the long term.","PeriodicalId":21463,"journal":{"name":"Romanian Journal of Internal Medicine","volume":"60 1","pages":"56-65"},"PeriodicalIF":1.9,"publicationDate":"2022-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39358222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Cardiac biomarkers alterations in patients with SARS-CoV-2 infection. SARS-CoV-2感染患者心脏生物标志物的改变

IF 1.9

Romanian Journal of Internal Medicine Pub Date : 2022-03-17 Print Date: 2022-03-01 DOI: 10.2478/rjim-2021-0037

Eleousa Oikonomou, Themistoklis Paraskevas, Dimitrios Velissaris

引用次数: 1

Hyper-inflammation after COVID-19 mARN vaccination: at the crossroads of multisystem inflammatory disease and adult-onset Still's disease. Does terminology matter? COVID-19 - mARN疫苗接种后的高度炎症:处于多系统炎症性疾病和成人发病斯蒂尔氏病的十字路口术语重要吗?

IF 1.9

Romanian Journal of Internal Medicine Pub Date : 2022-03-17 Print Date: 2022-03-01 DOI: 10.2478/rjim-2021-0035

Cristian Baicus, Caterina Delcea, Larisa Pinte, Gheorghe Andrei Dan

{"title":"Hyper-inflammation after COVID-19 mARN vaccination: at the crossroads of multisystem inflammatory disease and adult-onset Still's disease. Does terminology matter?","authors":"Cristian Baicus, Caterina Delcea, Larisa Pinte, Gheorghe Andrei Dan","doi":"10.2478/rjim-2021-0035","DOIUrl":"https://doi.org/10.2478/rjim-2021-0035","url":null,"abstract":"As the pandemic evolves, different facets of the SARS-CoV-2 infection, as well as immunization, with varying complexity and prognostic implications are discovered. One of them is the multisystem inflammatory syndrome (MIS)[1]. Characterized by elevated ferritin levels and hyper-inflammation with vital implications, MIS was proposed as the fifth clinical entity to constitute the “hyperferritinaemic syndromes”, alongside the macrophage activation syndrome (MAS), adult-onset Still’s disease (AOSD), catastrophic anti-phospholipid syndrome and septic shock [2]. Although most reports were related to SARS-COV-2 infection, MIS was recently described in relation to COVID-19 vaccination as well [3]. We hereby report the case of a previously healthy 22-year-old male, who received the first dose of BNT162b2 vaccine on May 1 2021. Thirteen days after vaccination, he developed a hyperinflammatory state, fulfilling the criteria for adult multisystem inflammatory syndrome (MIS-A) [2] (fever, sore throat, myalgias, myocarditis, hepatic injury, maculo-papular rash, diarrhoea, hypotension, and highly elevated inflammatory markers including a procalcitonin level of 33 ng/ml). He was initially admitted in another hospital’s Cardiology department with a diagnosis of acute coronary syndrome. At that moment the patient presented with chest pain, ST elevation on ECG, high troponin level, segmental left ventricular hypokinesia, and mid-range ejection fraction. The coronary angiography was normal,","PeriodicalId":21463,"journal":{"name":"Romanian Journal of Internal Medicine","volume":"60 1","pages":"3-5"},"PeriodicalIF":1.9,"publicationDate":"2022-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39406490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 19

The frailty phenotype in hemodialysis patients and its association with biochemical markers of mineral bone disorder, inflammation and nutrition. 血液透析患者的脆弱表型及其与骨矿物质紊乱、炎症和营养生化指标的关系。

IF 1.9

Romanian Journal of Internal Medicine Pub Date : 2022-03-17 Print Date: 2022-03-01 DOI: 10.2478/rjim-2021-0030

Alma Mutevelić-Turković, Halima Resić, Badema Čengić Roljić, Amela Dervišević, Amela Bećiragić

{"title":"The frailty phenotype in hemodialysis patients and its association with biochemical markers of mineral bone disorder, inflammation and nutrition.","authors":"Alma Mutevelić-Turković, Halima Resić, Badema Čengić Roljić, Amela Dervišević, Amela Bećiragić","doi":"10.2478/rjim-2021-0030","DOIUrl":"https://doi.org/10.2478/rjim-2021-0030","url":null,"abstract":"Introduction: Frailty is a state of increased vulnerability to physical stressors. It is common in patients with end-stage renal disease (ESRD) who are on hemodialysis (HD).The aim of this study was to analyze the presence of frailty phenotype among HD patients and to evaluate their interrelationship with different biochemical markers.Methods: For the frailty assessment the Frailty Phenotype by Fried et al. was used, where frailty was reported if three of the following criteria were met: unintentional weight loss, self-reported exhaustion, weakness, slow walking speed and low physical activity. From 281 HD patients, 126 patients were frail, 58 were pre-frail (two criteria were met) and the rest of the study population were robust (97 patients). BMI was calculated for all patients and venous blood samples were taken to determine laboratory parameters for bone alkaline phosphatase (BAP), phosphate (P), potassium (K), C-reactive protein (CRP) and albumin.Results: Patients who were on HD longer than 60 months have more characters of frailty. (p=0.019). A statistically significant positive correlations between frailty score and BAP (rho = 0.189; p = 0.001), and CRP (rho = 0.233; p < 0.001) were observed, and significant negative correlations between frailty score and albumin (rho = - 0.218; p < 0.001) and K (rho = - 0.198; p = 0.001).Conclusions: The associations of frailty with markers of mineral bone disorder, inflammation and nutrition indicate the importance of these parameters in the indirect assessment of the frailty phenotype in HD patients.","PeriodicalId":21463,"journal":{"name":"Romanian Journal of Internal Medicine","volume":"60 1","pages":"42-48"},"PeriodicalIF":1.9,"publicationDate":"2022-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39264374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3