Romanian Journal of Internal Medicine最新文献_第6页

Cross sectional study about nutritional risk factors of metabolically unhealthy obesity. 代谢不健康肥胖的营养危险因素横断面研究。

IF 1.9

Romanian Journal of Internal Medicine Pub Date : 2023-03-01 DOI: 10.2478/rjim-2022-0023

Rym Ben Othman, Olfa Berriche, Amel Gamoudi, Ramla Mizouri, Donia Jerab, Nadia Ben Amor, Faten Mahjoub, Henda Jamoussi

{"title":"Cross sectional study about nutritional risk factors of metabolically unhealthy obesity.","authors":"Rym Ben Othman, Olfa Berriche, Amel Gamoudi, Ramla Mizouri, Donia Jerab, Nadia Ben Amor, Faten Mahjoub, Henda Jamoussi","doi":"10.2478/rjim-2022-0023","DOIUrl":"https://doi.org/10.2478/rjim-2022-0023","url":null,"abstract":"Introduction: A substantial proportion of obese subjects are metabolically healthy and free from metabolic complications. Many mechanisms that could explain the existence of the metabolically healthy obese phenotype have been suggested, involving in particular a healthy lifestyle and diet. The aim of this study was to study the anthropometric, nutritional and biological profile of two groups: obese with metabolic syndrome (MS+) and obese without metabolic syndrome (MS-).Methods: It is a cross-sectional study, conducted between January 2022 and 15 March 2022. We recruited 90 obese MS+ and 82 obese MS - . Both groups were matched for age and sex. The glycemia, triglycerides (TG), total cholesterol (TC), HDL-C, LDL-C were measured as well as the body composition and anthropometric data. The diet was determined by the 24-hour recalls. Eating disorders, sleep disorders (PSS4 scale) and depression (HADS) were also searched.Results: In MS+ group we noticed: higher BMI, waist circumference, more caloric diet, elevated consumption of saccharides. This group had more eating disorders such as night eating syndrome and bulimia and sleeping disorders (sleep onset and total insomnia). MS + group was more stressed and depressed. The MS - group had a Mediterranean diet and had more intake of: EPA, DHA, olive oil, green tea, oleaginous fruits, linseed, vegetables and whole grains. They also practiced more fasting.Conclusions: It is important to know the protective nutritional factors of the metabolic syndrome in order to be able to focus on them during education sessions and thus protect the obese from metabolic complications.","PeriodicalId":21463,"journal":{"name":"Romanian Journal of Internal Medicine","volume":"61 1","pages":"53-62"},"PeriodicalIF":1.9,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9134380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnosis, symptoms, and treatment knowledge of aberrant right subclavian artery in followers of a social media group. 某社交媒体群体关注者右锁骨下动脉异常的诊断、症状及治疗知识

IF 1.9

Romanian Journal of Internal Medicine Pub Date : 2023-03-01 DOI: 10.2478/rjim-2022-0019

Caroline G Olson, Pedro Cortés, Fernando F Stancampiano, Jose R Valery, Yan Bi, Alberto Pocchetino, Dana M Harris

引用次数: 0

Effects of underlying heart failure on outcomes of COVID-19; a systematic review and meta-analysis. 潜在心力衰竭对COVID-19预后的影响系统回顾和荟萃分析。

IF 1.9

Romanian Journal of Internal Medicine Pub Date : 2023-03-01 DOI: 10.2478/rjim-2022-0021

Soroush Morsali, Erfan Rezazadeh-Gavgani, Mobina Oladghaffari, Shirin Bahramian, Sina Hamzehzadeh, Zahra Samadifar, Elgar Enamzadeh, Zahra Sheikhalipour, Haniyeh Moradi, Hanieh Salehi Pourmehr, Amirreza Naseri, Mohammadreza Taban-Sadeghi, Sara Daneshvar

{"title":"Effects of underlying heart failure on outcomes of COVID-19; a systematic review and meta-analysis.","authors":"Soroush Morsali, Erfan Rezazadeh-Gavgani, Mobina Oladghaffari, Shirin Bahramian, Sina Hamzehzadeh, Zahra Samadifar, Elgar Enamzadeh, Zahra Sheikhalipour, Haniyeh Moradi, Hanieh Salehi Pourmehr, Amirreza Naseri, Mohammadreza Taban-Sadeghi, Sara Daneshvar","doi":"10.2478/rjim-2022-0021","DOIUrl":"https://doi.org/10.2478/rjim-2022-0021","url":null,"abstract":"Background: The risk for worse outcomes of COVID-19 (Coronavirus 2019 disease) is higher in patients with cardiac conditions. In this study, we aim to investigate the risks of COVID-19-induced conditions in cases with underlying heart failure. Methods: We systematically searched PubMed, Scopus, Ovid, ProQuest, Web of Science, and the Cochrane library, to collect the English language articles that investigated patients with underlying heart failure who get infected by COVID-19. The second version of comprehensive meta-analysis (CMA.2) software was used to conduct the meta-analysis. Results: From 5997 publications, our eligibility criteria were met by 27 studies. Overall, outcomes investigated in all studies include but are not limited to mortality rate, length of hospitalization, need for Intensive care unit (ICU) admission, need for mechanical ventilation, and major cardiovascular conditions. Regarding mortality heart failure patients were more susceptible to death (OR:2.570, 95%CI: 2.085 to 3.169; p-value:<0.001). Also in heart failure patients, the risk of mechanical ventilation was higher (OR:1.707, 95%CI: 1.113 to 2.617; p-value: 0.014). Conclusion: Pre-existing heart failure is associated with the increased risk of mortality and the need for mechanical ventilation while getting infected with COVID-19. Finding an answer to determine the risk of hospitalization, length of stay, readmission rate, and multiorgan failure is necessary for further development of preventive care and making a plan for providing optimal healthcare facilities for these patients.","PeriodicalId":21463,"journal":{"name":"Romanian Journal of Internal Medicine","volume":"61 1","pages":"6-27"},"PeriodicalIF":1.9,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9142741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A review of transthyretin cardiac amyloidosis. 转甲状腺素型心脏淀粉样变性的研究进展。

IF 1.9

Romanian Journal of Internal Medicine Pub Date : 2023-03-01 DOI: 10.2478/rjim-2022-0018

Nikita Jhawar, Juan Carlos Leoni Moreno, Razvan Chirila

引用次数: 0

Pre-treatment Neutrophil-to-Lymphocyte Ratio significantly affects progression free survival in positive EGFR mutation advanced lung adenocarcinoma with EGFR-TKI treatment in Bali, Indonesia. 在印度尼西亚巴厘岛，治疗前中性粒细胞与淋巴细胞比率显著影响EGFR阳性突变晚期肺腺癌患者接受EGFR- tki治疗的无进展生存期。

IF 1.9

Romanian Journal of Internal Medicine Pub Date : 2023-03-01 DOI: 10.2478/rjim-2022-0020

Ni Putu Ayu Widiasari, Ida Bagus Ngurah Rai, Ida Ayu Jasminarti Dk, I Gede Ketut Sajinadiyasa, Ni Wayan Candrawati, Ni Luh Putu Eka Arisanti

{"title":"Pre-treatment Neutrophil-to-Lymphocyte Ratio significantly affects progression free survival in positive EGFR mutation advanced lung adenocarcinoma with EGFR-TKI treatment in Bali, Indonesia.","authors":"Ni Putu Ayu Widiasari, Ida Bagus Ngurah Rai, Ida Ayu Jasminarti Dk, I Gede Ketut Sajinadiyasa, Ni Wayan Candrawati, Ni Luh Putu Eka Arisanti","doi":"10.2478/rjim-2022-0020","DOIUrl":"https://doi.org/10.2478/rjim-2022-0020","url":null,"abstract":"Introduction: Today, recommendations about initial Response Evaluation Criteria in Solid Tumor (RECIST) and its frequency still vary, while early diagnosis of progression affects patient's prognosis and subsequent treatment options. Methods: This study aims to examine Progression Free Survival (PFS) of positive EGFR mutations advanced lung adenocarcinoma receiving Tyrosine Kinase Inhibitor (TKI) and factors that influence it. This was an observational study with retrospective cohort design conducted at Prof IGNG Ngoerah Hospital from January to December 2021. Sample was data from Epidermal Growth Factor Receptor (EGFR) positive mutation advanced lung adenocarcinoma patient who were treated with EGFR-TKI at Prof IGNG Ngoerah Hospital, Denpasar, Bali from January 2017 to February 2021. Total sample was 63. Results: Median PFS was 12 months (95% CI 10.28-13.71) and minimum PFS was 3 months. In univariate analysis, Hazard Ration (HR) of older age, smoker, distant metastasis, brain metastasis, increased Neutrophil-to-Lymphocyte Ration (NLR), and exon 21 mutation to shorter PFS was 0.99 (95% CI 0.95-1.02); 1.03 (95% CI 0.57-1.85); 1.45 (95% CI 0.85-2.49); 2.14 (95% CI 1.02-4.49); 1.08 (95% CI 1.03-1.13); and 1.21 (95% CI 0.67-2.18). Multivariate analysis showed only increased NLR affected PFS significantly with HR 1.06 (95% CI 1.007-1.13). Conclusion: Median PFS of EGFR positive mutation advanced lung adenocarcinoma patients who received TKI was 12 months and minimum value was 3 months. Increased age, smoking, distant metastases, brain metastases, and exon 21 mutations were not associated with PFS. NLR significantly affected PFS.","PeriodicalId":21463,"journal":{"name":"Romanian Journal of Internal Medicine","volume":"61 1","pages":"63-71"},"PeriodicalIF":1.9,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9489362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

External validation of the 4C Mortality Score and PRIEST COVID-19 Clinical Severity Score in patients hospitalized with COVID-19 pneumonia in Greece. 希腊住院COVID-19肺炎患者4C死亡率评分和PRIEST COVID-19临床严重程度评分的外部验证

IF 1.9

Romanian Journal of Internal Medicine Pub Date : 2022-11-23 Print Date: 2022-12-01 DOI: 10.2478/rjim-2022-0015

Themistoklis Paraskevas, Christos Michailides, Iosif Karalis, Anastasios Kantanis, Charikleia Chourpiliadi, Evgenia Matthaiakaki, Markos Marangos, Dimitrios Velissaris

{"title":"External validation of the 4C Mortality Score and PRIEST COVID-19 Clinical Severity Score in patients hospitalized with COVID-19 pneumonia in Greece.","authors":"Themistoklis Paraskevas, Christos Michailides, Iosif Karalis, Anastasios Kantanis, Charikleia Chourpiliadi, Evgenia Matthaiakaki, Markos Marangos, Dimitrios Velissaris","doi":"10.2478/rjim-2022-0015","DOIUrl":"https://doi.org/10.2478/rjim-2022-0015","url":null,"abstract":"Background: Prognostic scores can be used to facilitate better management of patients suffering from life-threatening diseases, provided that they have been tested in the population of interest. Aim: To perform external validation of the 4C Mortality Score and PRIEST COVID-19 Clinical Severity Score. Study Design: Prospective observational Study. Methods: Patients hospitalized with COVID-19 pneumonia in a tertiary hospital in Greece were enrolled in the study. The prognostic scores were calculated based on hospital admission data and ROC curve analysis was performed. We assessed a composite outcome of either in-hospital death or need for invasive ventilation. Results: Both 4C and PRIEST scores showed good discriminative ability with an AUC value of 0.826 (CI 95%: 0.765-0.887) and 0.852 (CI 95%: 0.793-0.910) respectively. Based on the Youden Index the optimal cut-off for the 4C score was 11 (Sensitivity 75%, Specificity 75.5%) and 10 for the PRIEST score (Sensitivity 83% and Specificity 69.4%). Calibration was adequate for both scores, except for the low and very high risk groups in the PRIEST score. Conclusion: The 4C Mortality Score and PRIEST COVID-19 Clinical Severity Score can be used for early identification of patients with poor prognosis in a Greek population cohort hospitalized with COVID-19.","PeriodicalId":21463,"journal":{"name":"Romanian Journal of Internal Medicine","volume":"60 4","pages":"244-249"},"PeriodicalIF":1.9,"publicationDate":"2022-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33481296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Comparison of scoring systems for predicting remission of type 2 diabetes in sleeve gastrectomy patients. 预测袖式胃切除术患者2型糖尿病缓解的评分系统比较。

IF 1.9

Romanian Journal of Internal Medicine Pub Date : 2022-11-23 Print Date: 2022-12-01 DOI: 10.2478/rjim-2022-0016

Suleyman Baldane, Murat Celik, Muslu Kazim Korez, Emine Gul Baldane, Huseyin Yilmaz, Sedat Abusoglu, Levent Kebapcilar, Husnu Alptekin

{"title":"Comparison of scoring systems for predicting remission of type 2 diabetes in sleeve gastrectomy patients.","authors":"Suleyman Baldane, Murat Celik, Muslu Kazim Korez, Emine Gul Baldane, Huseyin Yilmaz, Sedat Abusoglu, Levent Kebapcilar, Husnu Alptekin","doi":"10.2478/rjim-2022-0016","DOIUrl":"https://doi.org/10.2478/rjim-2022-0016","url":null,"abstract":"Introduction: This study aims to compare the predictive capacity of ABCD, DiaRem2, Ad-DiaRem, and DiaBetter scoring systems for type 2 diabetes mellitus (T2DM) remission in Turkish adult morbidly obese patients who underwent SG. Methods: This retrospective cohort study included 80 patients who underwent sleeve gastrectomy (SG) operation who were diagnosed with T2DM preoperatively, and had at least one-year follow-up after surgery. Because bariatric surgery is performed on patients with class III obesity (BMI ≥ 40 kg/m2) or class II obesity (BMI ≥ 35 kg/m2) with obesity releated comorbid conditions in our hospital, our study cohort consisted of these patients. Results: The diagnostic performance of the DiaBetter, DiaRem2, Ad-DiaRem and ABCD for identifying diabetes remission, assessed by the AUC was 0.882 (95% CI, 0.807-0.958, p < 0.001), 0.862 (95% CI, 0.779-0.945, p < 0.001), 0.849 (95% CI, 0.766-0.932, p < 0.001) and 0.726 (95% CI, 0.601-0.851, p = 0.002), respectively. The AUCs of the Ad-Diarem, DiaBetter and DiaRem2 were statistically higher than AUC of the ABCD (all p-value < 0.001). Besides, there was no statistically significant difference in AUCs of the Ad-Diarem, DiaBetter and DiaRem scores (all p-value > 0.05). Conclusion: Ad-Dairem, DiaBetter and DaiRem scoring systems were found to provide a successful prediction for diabetes remission in sleeve gastrectomy patients. It was observed that the predictive power of the ABCD scoring system was lower than the other systems. We think that the use of scoring systems for diabetes remission, which have a simple use, will become widespread.","PeriodicalId":21463,"journal":{"name":"Romanian Journal of Internal Medicine","volume":"60 4","pages":"235-243"},"PeriodicalIF":1.9,"publicationDate":"2022-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33481338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between serum midkine levels and tumor size in Indonesian hepatocellular carcinoma patients: a cross-sectional study. 印度尼西亚肝细胞癌患者血清midkine水平与肿瘤大小之间的关系:一项横断面研究。

IF 1.9

Romanian Journal of Internal Medicine Pub Date : 2022-11-23 Print Date: 2022-12-01 DOI: 10.2478/rjim-2022-0014

Darmadi Darmadi, Riska Habriel Ruslie, Cennikon Pakpahan

{"title":"Association between serum midkine levels and tumor size in Indonesian hepatocellular carcinoma patients: a cross-sectional study.","authors":"Darmadi Darmadi, Riska Habriel Ruslie, Cennikon Pakpahan","doi":"10.2478/rjim-2022-0014","DOIUrl":"https://doi.org/10.2478/rjim-2022-0014","url":null,"abstract":"Background: The incidence of liver cancer is increased worldwide with 75%-85% diagnosed as hepatocellular carcinoma (HCC). Current practice has low sensitivity limitations to diagnose the early stages of HCC, thus urging the need for a biomarker with higher sensitivity to detect HCC, specifically in the early stage. This study aimed to determine the association between midkine levels and progressiveness of hepatocellular carcinoma (HCC), according to tumor size, Barcelona Clinic Liver Cancer (BCLC), and presence of portal venous thrombosis. Methods: This cross-sectional study involved 100 patients in Adam Malik General Hospital diagnosed with HCC, collected with a consecutive sampling method, whose diagnoses were confirmed by findings of hypervascular on arterial phase imaging and portal vein or delayed phase washout triple-phase CT Scan. Samples are later categorized according to Barcelona Clinic Liver Cancer (BCLC) stages, tumor size, and presence of portal venous thrombosis. Blood samples were drawn to measure serum midkine using ELISA. Kruskal-Wallis and Mann-Whitney U tests were conducted to determine the difference of midkine levels based on tumor size, BCLC staging, and presence of portal venous thrombosis. Results: Serum midkine level shows a significant difference over tumor size (p=0.014), no significant difference found compared to BCLC stages and presence of portal venous thrombosis. Conclusion: Serum midkine levels are associated with the tumor size of HCC, thus helping physicians determine treatment plans.","PeriodicalId":21463,"journal":{"name":"Romanian Journal of Internal Medicine","volume":"60 4","pages":"229-234"},"PeriodicalIF":1.9,"publicationDate":"2022-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33481695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Autoimmune polyglandular syndrome type II presenting as subacute combined degeneration of spinal cord: a neuroendocrinology crossroad. 表现为亚急性脊髓合并变性的自身免疫性多腺综合征II型:神经内分泌学的十字路口

IF 1.9

Romanian Journal of Internal Medicine Pub Date : 2022-06-14 Print Date: 2022-06-01 DOI: 10.2478/rjim-2021-0038

Prateek Bapat, Suman Kushwaha, Chirag Gupta, R Kirangowda, Vaibhav Seth

{"title":"Autoimmune polyglandular syndrome type II presenting as subacute combined degeneration of spinal cord: a neuroendocrinology crossroad.","authors":"Prateek Bapat, Suman Kushwaha, Chirag Gupta, R Kirangowda, Vaibhav Seth","doi":"10.2478/rjim-2021-0038","DOIUrl":"https://doi.org/10.2478/rjim-2021-0038","url":null,"abstract":"Introduction: Autoimmune polyglandular syndrome (APS) is a condition having multiple endocrine abnormalities. It is divided into three types depending on the involvement of various endocrinopathies. It is also associated with other systemic involvement. The basic pathophysiology of this syndrome revolves around autoimmunity.Case presentation: We discuss the case of a 50-year-old gentleman who presented to us in emergency with subacute onset progressive weakness of both lower limbs followed by upper limbs. On examination, patient was confused and disoriented. General examination findings include hypotension, pallor, facial puffiness and vitiligo. Neurological examination revealed spasticity and motor weakness in all four limbs with extensor planter response. Sensory examination during hospital course revealed posterior column involvement. Laboratory and radiological investigations confirmed subacute combined degeneration of spinal cord secondary to pernicious anaemia, Addison's disease and autoimmune thyroid disease. The final diagnosis of autoimmune polyglandular syndrome type II was made after fulfilment of the required criteria.Conclusion: Autoimmune polyglandular syndrome type II can rarely present to neurologist as subacute combined degeneration of spinal cord. This syndrome and its systemic association should be kept in mind in order to reach the final diagnosis.","PeriodicalId":21463,"journal":{"name":"Romanian Journal of Internal Medicine","volume":"60 2","pages":"123-126"},"PeriodicalIF":1.9,"publicationDate":"2022-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39765127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Systematic approach to celiac disease: a comprehensive review for primary providers. 乳糜泻的系统方法:对主要提供者的全面回顾。

IF 1.9

Romanian Journal of Internal Medicine Pub Date : 2022-06-14 Print Date: 2022-06-01 DOI: 10.2478/rjim-2022-0002

Pedro Cortés, Dana M Harris, Yan Bi

引用次数: 2