体重指数与非酒精性脂肪性肝病组织学特征的相关性

IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL
Ana Calin-Necula, Vlad Enciu, Priscila Ologeanu, Alexandru Constantin Moldoveanu, Carmen Fierbinteanu Braticevici
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引用次数: 0

摘要

NAFLD与代谢综合征密切相关,多年来,脂肪肝是肥胖患者的独有特征。该研究试图评估身体质量指数(BMI)和身体周长是否与脂肪变性、纤维化或肝脏炎症活动相关。方法:对81例近期肝活检患者进行称重和测量。将活检结果与测量结果进行比较。结果:全体患者的平均BMI为30.16。不同炎症活动度组的BMI差异有统计学意义(p = 0.009):坏死炎症活动度较高的组BMI值也较高(各级别平均值:0-28、1-29、2-33、3-32、4-29)。两组脂肪变性程度差异无统计学意义(p = 0.871)。腰围方面,整体平均为90.70厘米/35.70英寸。脂肪变性类别之间存在显著差异(p < 0.001):脂肪变性评分较高的组腰围较高(每个级别的平均值:1-77厘米/ 30英寸,2-95厘米/ 37英寸,3-94厘米/ 37英寸)。两组的活动等级差异无统计学意义(p = 0.058)。结论:BMI和腰围是一种易于测量、无创的参数,可用于筛选坏死性炎症活动或严重脂肪变性的高危患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The correlation between Body Mass Index and histological features of Nonalcoholic Fatty Liver Disease.

Introduction: NAFLD is strongly associated with metabolic syndrome, and for many years, fatty liver was an exclusive feature of obese patients. The study tries to assess whether the body mass index (BMI) and body circumference is correlated to steatosis, fibrosis, or inflammatory activity of the liver. Methods: 81 patients with recent hepatic biopsy were included in the study and were weighed and measured. The biopsy results were compared to the measurements. Results: The average BMI overall for the whole lot was 30.16. There was a significant difference in BMI across the inflammatory activity categories (p = 0.009): groups with higher necro inflammatory activity tended to have higher BMI values (average values per grade: 0-28, 1-29, 2-33, 3-32, 4-29). There was no significant difference for grades of steatosis (p = 0.871). With regards to waist circumference, the overall average was 90.70cm/35.70in. There was a significant difference across the steatosis categories (p < 0.001): groups with higher steatosis scores had higher waist circumferences (average values per grade: 1-77cm / 30 in, 2-95 cm / 37 in, 3-94 cm / 37 in). There was no significant difference for grades of activity (p = 0.058). Conclusion: BMI and waist circumference are easy to measure, non-invasive parameters, which could be useful in screening patients at higher risk for necro inflammatory activity or severe steatosis.

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来源期刊
Romanian Journal of Internal Medicine
Romanian Journal of Internal Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
3.20
自引率
5.30%
发文量
35
审稿时长
15 weeks
期刊介绍: Romanian Journal of Physics is a journal publishing physics contributions on the following themes: •Theoretical Physics & Applied Mathematics •Nuclear Physics •Solid State Physics & Materials Science •Statistical Physics & Quantum Mechanics •Optics •Spectroscopy •Plasma & Lasers •Nuclear & Elementary Particles Physics •Atomic and Molecular Physics •Astrophysics •Atmosphere and Earth Science •Environment Protection
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