Revista de psiquiatria y salud mental最新文献

{"title":"Sensibilidad y especificidad de los criterios diagnósticos DSM-5 en el trastorno del espectro autista en una muestra de niños y adolescentes españoles","authors":"Ana Blázquez Hinojosa ,&nbsp;Luisa Lázaro Garcia ,&nbsp;Olga Puig Navarro ,&nbsp;Eva Varela Bondelle ,&nbsp;Rosa Calvo Escalona","doi":"10.1016/j.rpsm.2019.10.004","DOIUrl":"10.1016/j.rpsm.2019.10.004","url":null,"abstract":"<div><h3>Background</h3><p>Controversy exists regarding the DSM-5 criteria for autism spectrum disorders (ASD). Given the mixed results that have been reported, our main aim was to determine DSM-5 sensitivity and specificity in a child and adolescent Spanish sample. As secondary goals, we assessed the diagnostic stability of DSM-IV-TR in DSM-5, and clinical differences between children diagnosed with an ASD or a social (pragmatic) communication disorder (SPCD).</p></div><div><h3>Methods</h3><p>This study was carried out in 2017, reviewing the medical records of patients evaluated in our service. Items from a parent report measure of ASD symptoms (Autism Diagnostic Interview-Revised) were matched to DSM-5 criteria and used to assess the sensitivity and specificity of the DSM-5 criteria and current DSM-IV criteria when compared with clinical diagnoses.</p></div><div><h3>Results</h3><p>DSM-5 sensitivity ranged from 0.69 to 1.00, and was higher in females. By age, the DSM-5 and DSM-IV-TR criteria showed similar sensitivity. In the case of intellectual quotient, DSM-5 criteria sensitivity was lower for those in the “low-functioning” category. DSM-5 specificity ranged from 0.64 to 0.73, while DSM-5 specificity was similar for all phenotypic subgroups. With respect to stability, 83.3% of autism disorder cases retained a diagnosis of ASD using the DSM-5 criteria. With regard to differences between ASD and SPCD, we found that patients diagnosed with ASD received more pharmacological treatment than those diagnosed with SPCD.</p></div><div><h3>Conclusions</h3><p>Further research is required to confirm our results. Studies focusing on the SPCD phenotype will be necessary to determine outcome differences with ASD and the most effective diagnostic and therapeutic tools.</p></div>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":null,"pages":null},"PeriodicalIF":9.2,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989119300990/pdfft?md5=79259de42c79d30e7bf5bb92caa7ab58&pid=1-s2.0-S1888989119300990-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37480791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intoxicación por litio: la amenaza SILENTiosa","authors":"Álvaro Martínez-Martín ,&nbsp;Álvaro Sánchez-Larsen ,&nbsp;Carolina Sánchez-Mora ,&nbsp;Rocío Sáez-Povedano ,&nbsp;Tomás Segura","doi":"10.1016/j.rpsm.2020.06.006","DOIUrl":"10.1016/j.rpsm.2020.06.006","url":null,"abstract":"","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":null,"pages":null},"PeriodicalIF":9.2,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989120300756/pdfft?md5=7c639bb6920c68b54166d7a59b8be2a0&pid=1-s2.0-S1888989120300756-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38200848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real clinical setting intravenous ketamine use for treatment resistant depression: 12 month follow-up after initial response","authors":"Nora Olazabal ,&nbsp;Sonia Bustamante ,&nbsp;M. Aranzazu Madrazo ,&nbsp;Luis Osa ,&nbsp;Ana M. O’Neill of Tyrone ,&nbsp;Ana Catalán ,&nbsp;Miguel Angel González-Torres","doi":"10.1016/j.rpsm.2021.01.002","DOIUrl":"10.1016/j.rpsm.2021.01.002","url":null,"abstract":"","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":null,"pages":null},"PeriodicalIF":9.2,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989121000197/pdfft?md5=01bcfa21c34c9cfd58207dc439e6c942&pid=1-s2.0-S1888989121000197-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25311706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detección de ansiedad y depresión en Atención Primaria: utilidad de 2 escalas breves adaptadas a los nuevos criterios CIE-11-AP","authors":"Celso Iglesias García ,&nbsp;Pilar López García ,&nbsp;José Luis Ayuso Mateos ,&nbsp;José Ángel García ,&nbsp;Julio Bobes","doi":"10.1016/j.rpsm.2019.12.001","DOIUrl":"10.1016/j.rpsm.2019.12.001","url":null,"abstract":"<div><h3>Introduction</h3><p>The World Health Organization has developed a new classification of mental disorders in Primary Health Care (PHC), the ICD-11-PHC, in which there are changes in the diagnostic criteria of anxiety and depression disorder. In addition, 2 screening instruments have been developed for the detection of anxious and depressive symptoms according to the criteria of the new classification.</p></div><div><h3>Objectives</h3><p>To evaluate the capacity of the Spanish version of the 2 brief scales Dep5 and Anx5 to identify cases of depression and anxiety in PHC in Spain.</p></div><div><h3>Method</h3><p>A cross-sectional study conducted by 37 PHC physicians who selected 284 patients with suspected emotional distress. This sample was administered the screening scales (Anx5 and Dep5) and a diagnostic instrument (Clinical Interview Schedule-Revised) contemplating the new ICD-11 criteria as used as gold standard.</p></div><div><h3>Results</h3><p>The Anx5, using a cut-off point of 3, showed a sensitivity of 0.75 and specificity of 0.53. Using a cut-off point of 4, the Dep5 showed a sensitivity of 0.48 and a specificity of 0.8. The 2 scales together, with a cut-off point of 3 for each, classified correctly 73,57% as cases or non-cases. The diagnosis most frequently observed was anxious depression.</p></div><div><h3>Conclusions</h3><p>The screening scales for anxious and depressive symptoms (Anx5 and Dep5) are simple and easy-to-use instruments for assessing anxious and depressive symptoms in PHC. The reliability and validity data of each of the scales separately are limited but the figures improve when they are used together.</p></div>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":null,"pages":null},"PeriodicalIF":9.2,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989120300148/pdfft?md5=896ac08fa4679a9b4c3c2dee633d8bfc&pid=1-s2.0-S1888989120300148-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37601872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depression in late life: Linking the immunometabolic dysregulation with clinical features","authors":"Alejandro de la Torre-Luque ,&nbsp;Jose Luis Ayuso-Mateos","doi":"10.1016/j.rpsm.2021.06.004","DOIUrl":"10.1016/j.rpsm.2021.06.004","url":null,"abstract":"","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":null,"pages":null},"PeriodicalIF":9.2,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989121000653/pdfft?md5=efb83bb047c0fdc1a5b6bc6f035134a5&pid=1-s2.0-S1888989121000653-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39155272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation study of the Spanish brief version of TEMPS-A.","authors":"Jessica Zapata Téllez, Hiram Ortega Ortiz, Lizette Quiroz Casián, Claudia Becerra Palars, María Del Carmen Elizabeth Lara Muñoz, Gustavo H Vázquez","doi":"10.1016/j.rpsm.2021.08.002","DOIUrl":"10.1016/j.rpsm.2021.08.002","url":null,"abstract":"<p><strong>Introduction: </strong>Identifying affective temperaments could be useful both for understanding the normal behavioral variations in the general population and to establish if there is a clinical predisposition to certain disorders. Five affective temperaments have been proposed: depressive, cyclothymic, hyperthymic, irritable and anxious. Original instrument for measuring them (TEMPS-A) is a 110-item scale but many short versions in different languages have been validated. The aim of this study was to obtain a short self-administered Spanish version of TEMPS-A with good psychometric properties.</p><p><strong>Materials and methods: </strong>A sample of 550 students who answered the argentinean version of TEMPS-A was included, after psychometric analysis a comparison between inpatients with major depression and their matched controls by sex and age who answered the brief version was performed to get an external validation.</p><p><strong>Results: </strong>The sample was composed by 298 (54.2%) women. The mean age was 23.3 year (SD=6.2). A forced five factor analysis was performed. The 7 items with the highest factorial load (more than 0.350) for each subscale were included in the brief version. The Cronbach alpha's ranged from 0.690 to .800. The most prevalent temperament was hyperthymic followed by cyclothymic for students sample. Similarities between students and controls sample were observed, but not with patients with major depression.</p><p><strong>Conclusions: </strong>This brief Spanish version of TEMPS-A (35 items) has good psychometric properties and can be used in general and clinical population.</p>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":null,"pages":null},"PeriodicalIF":9.2,"publicationDate":"2021-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39383254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of aripiprazole and risperidone effectiveness in first episode non-affective psychosis: Rationale and design of a prospective, randomized, 3-phase, investigator-initiated study (PAFIP-3)","authors":"Mayoral-van Son J. ,&nbsp;Marcos Gómez-Revuelta ,&nbsp;Rosa Ayesa-Arriola ,&nbsp;Javier Vázquez-Bourgón ,&nbsp;Víctor Ortiz-García de la Foz ,&nbsp;Miguel Ruiz-Veguilla ,&nbsp;Nathalia Garrido ,&nbsp;Diana Tordesillas-Gutiérrez ,&nbsp;Esther Setién-Suero ,&nbsp;Benedicto Crespo-Facorro","doi":"10.1016/j.rpsm.2021.01.004","DOIUrl":"10.1016/j.rpsm.2021.01.004","url":null,"abstract":"<div><h3>Background</h3><p>Selecting the most effective treatment represents a critical challenge with the potential of modifying the long-term prognosis of individuals suffering a first break of psychosis. Head-to-head clinical trials comparing effectiveness among antipsychotic drugs in individuals with a first-episode of non-affective psychosis (FEP) are scarce.</p></div><div><h3>Methods</h3><p>The rationale and design of a 3 phases clinical trial (PAFIP-3, <span>NCT02305823</span><svg><path></path></svg>) comparing the effectiveness of aripiprazole and risperidone, and to additionally assess the benefits of an early use of clozapine in primary treatment-resistant patients is reported. The design encompasses of 5 work packages (medication algorithm, cognitive functioning, psychoeducation/vocational functioning, imaging and biological markers) addressing critical issues and needs of first episode psychosis individuals and their cares. The primary outcome measure was treatment effectiveness assessed by all-cause treatment discontinuation rate.</p></div><div><h3>Results</h3><p>266 individuals have been included in the randomization study phase I (risperidone vs. aripiprazole). At 3 months, the retention rate was of 94% (249/266), 48(19.3%) patients have gone through phase II (olanzapine treatment), and 7(2.8%) entered the clozapine phase (phase III).</p></div><div><h3>Discussion</h3><p>The PAFIP 3 clinical trial may provide relevant information about clinical guidelines to optimally treat patients with a first episode of non-affective psychosis and the benefits and risks of an early use of clozapine in treatment resistant patients.</p><p>Clinicaltrials.gov: <span>NCT02305823</span><svg><path></path></svg>.</p></div>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":null,"pages":null},"PeriodicalIF":9.2,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989121000215/pdfft?md5=4c865a3c729d7be9be5e792339b6a809&pid=1-s2.0-S1888989121000215-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85666110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive value of prolactin in first episode psychosis at ten years follow-up","authors":"Manuel Delgado-Alvarado ,&nbsp;Javier Vázquez-Bourgon ,&nbsp;Rosa Ayesa-Arriola ,&nbsp;Victor Ortiz-García de la Foz ,&nbsp;Jacqueline Mayoral-van Son ,&nbsp;Javier Labad ,&nbsp;Benedicto Crespo-Facorro","doi":"10.1016/j.rpsm.2020.10.004","DOIUrl":"10.1016/j.rpsm.2020.10.004","url":null,"abstract":"","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":null,"pages":null},"PeriodicalIF":9.2,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S188898912030118X/pdfft?md5=9a17ab90eea242559542382791893c73&pid=1-s2.0-S188898912030118X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88858807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amerindians may need clozapine dosing similar to that of Asians","authors":"Dinora F. González-Esquivel ,&nbsp;Helgi Jung-Cook ,&nbsp;Trino Baptista ,&nbsp;Jose de Leon","doi":"10.1016/j.rpsm.2020.11.002","DOIUrl":"10.1016/j.rpsm.2020.11.002","url":null,"abstract":"","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":null,"pages":null},"PeriodicalIF":9.2,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989120301257/pdfft?md5=37d903869ff7fe4f21c5fda490797559&pid=1-s2.0-S1888989120301257-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80534485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prevention of relapses in first episodes of schizophrenia: The 2EPs Project, background, rationale and study design","authors":"Miguel Bernardo ,&nbsp;Silvia Amoretti ,&nbsp;Manuel Jesús Cuesta ,&nbsp;Mara Parellada ,&nbsp;Gisela Mezquida ,&nbsp;2EPs Group ,&nbsp;The acronym 2EPs Group responds to the authorship of the principal investigators of the fifteen centres that have participated in this coordinated multicenter project,&nbsp;Ana González-Pinto ,&nbsp;Daniel Bergé ,&nbsp;Antonio Lobo ,&nbsp;Eduardo J. Aguilar ,&nbsp;Judith Usall ,&nbsp;Iluminada Corripio ,&nbsp;Julio Bobes ,&nbsp;Roberto Rodríguez-Jiménez ,&nbsp;Salvador Sarró ,&nbsp;Fernando Contreras ,&nbsp;Ángela Ibáñez ,&nbsp;Miguel Gutiérrez ,&nbsp;Juan Antonio Micó","doi":"10.1016/j.rpsm.2020.07.004","DOIUrl":"10.1016/j.rpsm.2020.07.004","url":null,"abstract":"<div><p>Up to 80% of first-episode psychosis patients suffer a relapse within five years of the remission. Relapse should be an important focus of prevention given the potential harm to the patient and family. It threatens to disrupt their psychosocial recovery, increases the risk of resistance to treatment and has been associated with greater direct and indirect costs for society.</p><p>Based on a previous project entitled “Genotype–phenotype and environment. Application to a predictive model in first psychotic episodes” (PEPs Project), the project “Clinical and neurobiological determinants of second episodes of schizophrenia. Longitudinal study of first episode of psychosis” was designed, also known as the 2EPs Project. It aimed to identify and characterize those factors that predict a relapse within the years immediately following a first episode. This project has focused on following the clinical course, with neuropsychological assessments, biological and neuroanatomical measures, genetic adherence and physical health monitoring in order to compare a subgroup of patients with a second episode to another group of patients which remains in remission. The main objective of the present article is to describe the rationale of the 2EPs Project, explaining the measurement approach adopted and providing an overview of the selected clinical and functional measures.</p><p>2EPs Project is a multicenter, coordinated, naturalistic, longitudinal follow-up study over three years in a Spanish sample of patients in remission after a first-psychotic episode of schizophrenia. It is closely monitoring the clinical course of the cases recruited to compare the subgroup of patients with a second episode to that which remains in remission. The sample is composed of 223 subjects recruited from 15 clinical centres in Spain with experience of the preceding PEPs Study project, albeit 2EPs being an expanded version with new basic groups in biological research. From the total sample recruited, 63 patients presented a relapse (44%).</p><p>2EPs arose to characterize first episodes in an exhaustive, novel and multimodal way, thus contributing towards the development of a predictive model of relapse. Identifying the characteristics of patients who relapse could improve early detection and intervention.</p></div>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":null,"pages":null},"PeriodicalIF":9.2,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989120300987/pdfft?md5=824b8128318f3022b23e7ef1edd5d0c0&pid=1-s2.0-S1888989120300987-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73834568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}