Saudi Journal of Medical and Pharmaceutical Sciences最新文献

{"title":"Features of Obtaining and Properties of Fulvic Acid from the Peat of Nizhny Novgorod Region","authors":"Konnova, M. A, Volkov, A. A, Kostryukov, S. G, Melnikova, N. B","doi":"10.36348/sjmps.2023.v09i09.004","DOIUrl":"https://doi.org/10.36348/sjmps.2023.v09i09.004","url":null,"abstract":"Properties of fulvic acid (FA) extracted from the peat of the Nizhny Novgorod region of Russia by ultrasonic extraction with alkaline or ethanol solutions and further purification were studied in the paper. The purification of FA by the Lamar method was shown to possibly lead to the formation of FA polymorphs of the same composition but different structure (IR, solid-state 13С NMR, fluorescence, UV, energy-dispersive X-ray spectroscopy, SEM and optical microscopy, concentration of carboxyl and phenol groups). Aggregation of FA polymorphs in water led to the formation of nanoparticles with the average size of 8–10 nm and the zeta potential of –22 to –27 mV. The formation and properties of polymorphic supramolecular structures are greatly influenced by the drying mode. The solubility of the two FA polymorphs varied from freely soluble (3.3 mL of water per gram) after the FA solution freeze-drying to soluble (12 mL of water per gram) after the FA solution vacuum drying. The FA sample extracted by ethanol ultrasonic extraction from the peat, followed by convection drying, had a solubility of 666.7 mL of water per gram (Slightly soluble), a zeta potential of -6 mV, and a particle size of 15–20 nm.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135786014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge and Training Needs of Primary Healthcare Physicians Regarding Obesity Management in Saudi Arabia: A Systematic Review","authors":"Alhazmi Trke Mohammed A, Maha Khaled H. Alenezi, Meshari Fazzaa S. Alanazi, Almatrafi Abdulaziz Ramdan H","doi":"10.36348/sjmps.2023.v09i09.003","DOIUrl":"https://doi.org/10.36348/sjmps.2023.v09i09.003","url":null,"abstract":"Background/Objectives: Obesity has surged globally, posing various health risks. Its prevalence and management, especially in primary health care settings in Saudi Arabia, have recently been under the spotlight. This research synthesized various studies, analyzing the knowledge and preparedness of primary health care physicians in addressing and management of obesity in Saudi Arabia. Methods: An exhaustive evaluation of studies spanning different regions of Saudi Arabia, focusing on physicians' capabilities, knowledge, and practices in obesity management. This analysis also took into account the comparative approaches of countries like Canada, the UK, USA, and Hungary. Various factors, such as specialized obesity treatments, patient-centric approaches in pediatric obesity, career stages of physicians, obesity's correlation with noncommunicable diseases, and nutritional competence, were studied. Results: Nine studies were included. From a collective pool of 2430 participants across the discussed studies, challenges in obesity management were consistent. Despite having an understanding of obesity, there was a significant knowledge gap in specialized treatments, with many physicians feeling unprepared to manage the condition. Factors such as geographical diversity, physicians' experiences, external influences on pediatric obesity management, and the correlation between obesity and other health conditions were highlighted. The need for effective nutrition care, despite perceived capability, was a notable finding. Conclusion: Saudi Arabia faces a significant challenge in obesity management in primary health care settings, marked by knowledge gaps and the need for continuous training. The analyzed studies emphasize the importance of tailored interventions, robust training modules, and public health campaigns within Saudi Arabia's unique context to combat the obesity epidemic effectively.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136193754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Per Oral Endoscopic Myotomy in Treatment of Moroccan Patients with Achalasia: Prelimanary Result","authors":"Mohamed Acharki, Soumaya Merzouk, Mouna Salihoun, Ilham Serraj, Nawal Kabbaj","doi":"10.36348/sjmps.2023.v09i09.002","DOIUrl":"https://doi.org/10.36348/sjmps.2023.v09i09.002","url":null,"abstract":"Background and Objectives: Endoscopic myotomy is a recent technique that did spread quickly across high-income countries. The aim of this study is to report the experience of our department regarding the practice of POEM. Study design: It is a retrospective study including 13 patients with achalasia treated by POEM at the Department of Digestive Functional Explorations (EFD-HGE) of University Hospital Center Ibn Sina of Rabat, between January 2017 and June 2023. There was a break during the COVID19 pandemic and the endoscopic activity was stopped for a while. Results: The median age was 40, 46. Women were more affected than men: 69% and 31% respectively. Only 15% of cases had previous treatment (pneumatic dilation/surgical myotomy). The clinical success rate reached 84.6%. The mean of Eckardt scores decreased from 8 at baseline to 3 at 2 months. The IRP’s mean decreased from 23.9 mmHg to 15.6 mmHg after the gesture. The post-POEM reflux rate was less than 16%, but the rate of serious adverse events was relatively high. Conclusions: POEM is an effective procedure to treat achalasia with a low morbidity, provided that it is carried out in an expert center with suitable and good quality material.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136363393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and Radiological outcome of Gartland Type-III closed supercondylar fracture of humerus in Children treatment by percutaneous K-wires fixation","authors":"Md. Insanul Alam, Hosne Ara, Md. Faridul Islam, Md. Ismail Hossain, Razia Sultana, Mahbubul Alama, Khaleda Akter, Md. Saidul Hoque, Zubayer Ashraf, Md. Anisuzzaman Md. Anisuzzaman","doi":"10.36348/sjmps.2023.v09i09.001","DOIUrl":"https://doi.org/10.36348/sjmps.2023.v09i09.001","url":null,"abstract":"Introduction: Supracondylar fracture of the humerus is the most common fracture of the elbow in children and displacement is common. Main problem regarding management of early supracondylar fracture are obtaining and maintaining reduction as they commonly present in the emergency department with varying degrees of soft tissue swelling. Objective: To assess the Clinical and Radiological Outcome Type III Closed Supracondylar Fracture Of Humerus in Children treatment by percutaneous K-wires fixation. Methods: This study was carried out at the NITOR, over a period of 24 months between January 2015 to December 2016. The total number of patients were 30. All patients suffering from closed supracondylar fracture of humerus in children. Each Gartland type-III closed Supracondylar Fracture of humerus among supracondylar Fracture in children attended at emergency, outpatient department and admitted in NITOR. Results: A total number of 30 patients were enrolled in this study as per inclusion and exclusion criteria. Diagnosis of the supracondylar fracture of humerus was made by history, clinical examination and radiological evidence. The youngest patient in our series is 3 years old and the oldest is 12 years. Majority were in 5-8years. Among 30 patients mean age was 6.85 years with SD = ± 2.37 years. In the present series, maximum patients were male 22 (73.3%) and 8 (26.7%) patients were female. Male female ratio 2.75:1. Male patients were predominant in this study. The results are shown in table-I. In the present series, 19 (63.3%) with left sided supracondylar fracture of humerus and 11(36.7%) presented with right sided supacondylar fracture of humerus. The results are shown in Table-II. Out of 30 cases 15 (50%) cases gave history of fall from tree, 6(20%) cases gave history of fall from bed, 4(13.3%) cases gave history of fall during playing, 5(16.7%) cases gave history of RTA due to fall from bicycle. In the present series, postero-medial fracture was found in 18(60.0%) cases and postero-lateral fracture in 12 (40.0%) cases. Out of 30 patient’s about 16 (53.3%) of the patient’s was operated between (13-18) hours of receiving injury, 11 (36.7%) with in (7-12) hours and 1 (3.3%) within (0-6) hours of injury and 2(6.7%) with in (19-24) hours of injury, mean interval between injury and Operation was 8.06 ± 5.52 hours. Out of 30 patient’s, 22 (73.3%) of the patients stayed in the hospital for 1 day and 8 (26.7%) of the patients stayed in the hospital for 2 days. The mean duration of hospital stay was 1.26 ± 0.45 days. In this series, among 30 Patients, 27(90.0%) had radiologically sufficient callus formation and 3(10.0%) patients had no sufficient callus formation. Functional outcome was satisfactory result (Excellent, Good and Fair) were 27(90.0%) and unsatisfactory result (poor) was 3 (10.0%). Conclusion: Finally, the result shows that in Gartland type-III closed supracondylar fracture of the humerus, closed reduction and stabilization by two lateral paral","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75863559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Report on Recurrent Gastro Intestinal Stromal Tumor (GIST)","authors":"Rathuna Rajeev, Shanet Nissy Nelson, A. Malik","doi":"10.36348/sjmps.2023.v09i08.017","DOIUrl":"https://doi.org/10.36348/sjmps.2023.v09i08.017","url":null,"abstract":"Gastrointestinal stromal tumor (GIST) is a rare sarcoma, typically starts in the cells that line the gastrointestinal tract’s (GIT) wall. While certain GISTs may develop slowly over time, others might spread drastically. However, it will indicate recurrence for certain people. Patients with locally resectable gastro intestinal stromal tumours continue to be treated primarily with radical surgery, which, in more than 50% of instances, results in a long-term remission of this disease. The first targeted medication for the GISTs treatment was the tyrosine kinase inhibitor imatinib, and is now the preferred option for treating advanced gastro intestinal stromal tumours. This case highlights recurrence of GIST for two times even after laparotomy which provides an information, that the hazards associated with this type of tumour must be reduced by receiving appropriate therapy because it can recur.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85342400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological Aspects of Lefort II Fractures Treated at Nianankoro Fomba Hospital in Segou: About 17 Cases","authors":"BM Dramé, I. Diarra, H. Toungara, O. Koné, M. Diallo, N. Koné, A. Touré, C. Touré, B. Dramé","doi":"10.36348/sjmps.2023.v09i08.016","DOIUrl":"https://doi.org/10.36348/sjmps.2023.v09i08.016","url":null,"abstract":"The Lefort II fracture (pyramidal fracture) or high transfacial is a solution of bone continuity of the middle stage of the face whose fracture line concerns the glabella, the ethmoid massif, the two maxillary sinuses and the pterygoids causing more or less important the mobility of the middle stage of the face. Objectives: of this study were to study the frequency of Lefort II fractures at Nianankoro FOMBA Hospital in Segou; to study the target population of Lefort II fractures at the Nianankoro FOMBA hospital in Segou; evaluate the treatment option for this pathology; to study the fate of treated patients. This was a prospective study, carried out in the stomatology and maxillofacial surgery department of Nianankoro FOMBA Hospital in Ségou over a period of 3 years, i.e. 36 months from October 1, 2016 to October 1, 2019. It covered all cases of Lefort II fractures admitted to this department for their care. During our study we recorded 225 cases of maxillofacial trauma including 17 cases of Lefort II fractures or 7.55% of all traumatic injuries admitted to the service. Lefort II fractures are a social and public health problem affecting mainly young male subjects in the 20 to 29 age group most often following accidents on public roads. Their diagnosis is made by clinical examination associated with paraclinical examination (computed tomography) which makes it possible to locate the fracture foci.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74508007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Usefulness of Endoscopic Ultrasound in the Diagnosis of Gastric Tumours","authors":"Abdouh Chaimae, Salihoun Mouna, Serraj Ilham, Acharki Mohamed, Kabbaj Nawal","doi":"10.36348/sjmps.2023.v09i08.015","DOIUrl":"https://doi.org/10.36348/sjmps.2023.v09i08.015","url":null,"abstract":"Endoscopic ultrasound (EUS) is is a technique used for the exploration of the digestive system, enabling the diagnosis and classification of gastric tumors. The aim of our study was to describe the contribution of EUS and fine needle aspiration in the diagnosis and determination of the histological type of gastric tumors. Our study consists of a retrospective descriptive study involving 36 patients. The mean age was 54 ± 14.4 years, with a female-to-male sex ratio of 2. EUS revealed an ulcerated and polypoid appearance with prominent folds in half of the cases. Fine needle aspiration biopsy was performed in 80.5% of cases. The histopathological findings were predominantly gastrointestinal stromal tumors and adenocarcinomas.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79652816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and Analgesic Efficacy of General Versus Caudal Block in Pediatric Infra Umbilical Surgery","authors":"Mohammed Mamun Morshed","doi":"10.36348/sjmps.2023.v09i08.014","DOIUrl":"https://doi.org/10.36348/sjmps.2023.v09i08.014","url":null,"abstract":"Background: Caudal analgesia has become popular in the management of intraoperative and postoperative pain management, further with the use of adjuvants to prolong its duration each with varying results. Caudal block is the most preferred postoperative analgesia in pediatrics, despite its limited duration of action. Many additives are used to improve the effectiveness of caudal blocks, such as opioids or a2 agonists. Recently, the use of caudal dexamethasone as an analgesic after surgery has increased. Objectives: The aim of this study is to evaluate the safety and analgesic efficacy of general versus caudal block in pediatric infra umbilical surgery. Methods: This is an observational study. This study was carried out on 50 patients the find out about the population including children in the Department of Anaesthesia, Uttara Adhunik Medical College Hospital, Dhaka, Bangladesh. The duration of the period from January 2022 to December 2022. Statistical evaluation of the results used to be got via the use of a window-based computer software program devised with Statistical Packages for Social Sciences (SPSS-24). Results: The mean duration of postoperative analgesia was 3 times longer in Bupivacaine with preservative free Clonidine Group. Bupivacaine solution Group received significantly more doses of rescue analgesic than Bupivacaine with preservative free Clonidine Group (p-value of 0.004). There was no significant bradycardia, hypotension, sedation or urinary retention in either of the groups. There was no residual motor blockade at 6 hours. Incidence of vomiting was similar in both the groups. Conclusion: Dexamethasone in combination with bupivacaine reduces postoperative pain intensity and total analgesic consumption and prolongs analgesia.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"247 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75869469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Pattern of Alleged Rape Case in Dhaka City","authors":"Mohammad Kykobad Hosain, B. K. Das, Faizunnahar Faizunnahar, M. Das, Md. Ghulam Mostofa","doi":"10.36348/sjmps.2023.v09i08.012","DOIUrl":"https://doi.org/10.36348/sjmps.2023.v09i08.012","url":null,"abstract":"Background: Rape is a common social problem having great implication on the Victim, family, Judiciary and state. However it is very difficult to prove the actual rape because it is difficult to establish whether it is a consented sex or actual rape. Objective: To assess the pattern of alleged rape case in Dhaka city. Method: 176 cases of alleged rape were studied during the period of 2019-2022 at the Tertiary hospital, Dhaka. Results: Of these, 130 cases had consented sexual intercourse. 46 victims were subjected to rape. Cases include different age groups, their occupations, living areas, time of arrival for medicolegal examination have been studied. Most of the cases were students. An alarming number of victims were subjected to gang rape. Examination and reporting of the cases with have been discussed. Conclusion: This study shows that only one fourth of the alleged rape victims are the real rape cases. The victims of other cases had consent to sexual intercourse. There were several victims below the age of consent who cannot give valid consent to sexual intercourse as per law.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78108666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and Feasibility of SAB in Otherwise Healthy Individuals Undergoing Laparoscopic Cholecystectomy","authors":"M. Begum, Md Abdul Baki, Kawser Ahmed, Nirmal Kumar Barman, Md. Monwar Hossein, Md Shafiqul Islam, Shiladitya Shil","doi":"10.36348/sjmps.2023.v09i08.013","DOIUrl":"https://doi.org/10.36348/sjmps.2023.v09i08.013","url":null,"abstract":"Background: The safety and feasibility of utilizing SAB as the sole anesthetic technique in otherwise healthy individuals undergoing laparoscopic cholecystectomy have been increasingly recognized. SAB offers potential advantages in terms of reduced complications, improved pain control, and avoidance of general anesthesia-related risks. Objective: To assess safety and feasibility of SAB in otherwise healthy individuals undergoing laparoscopic cholecystectomy. Method: The study included a cohort of 40 patients who underwent elective laparoscopic cholecystectomy and met specific inclusion criteria. All patients received a subarachnoid block (SAB) with 3 ml of 0.5% bupivacaine and 25 micrograms of fentanyl at the L2-L3 level. The laparoscopic cholecystectomy procedure was performed using a standard 4-port technique, while maintaining a low intra-abdominal pressure of 9-10 mm Hg through CO2 pneumoperitoneum. The patients were followed up at various time points, including 30 minutes, 4 hours, the time of discharge, and on the 7th day after the operation. Any voluntary or involuntary movements or exaggerated diaphragmatic excursions during the operation were carefully monitored. The study recorded parameters such as operation time, duration of operating room occupancy, length of hospital stay, post-operative pain levels, analgesic requirements, occurrences of nausea, vomiting, headache, right shoulder pain, wound-related complications, and patient satisfaction. Results: SAB demonstrated efficacy in all 40 patients undergoing surgery. Conversion to general anesthesia was required in two cases due to persisting low oxygen saturation. Hypotension occurred in 23.7% of patients, while 10.5% experienced right shoulder pain. The average operating time was 37.3 minutes, ranging from 21 to 77 minutes. Awkward movements and exaggerated respiratory excursions were observed in 23.7% and 18.4% of cases, respectively. Only two cases required conversion to general anesthesia. The mean hospital stay duration was 29.3 hours. No major complications were reported during the study. Conclusion: These findings suggest that SAB can be successfully and effectively used for laparoscopic cholecystectomy in healthy patients, providing a safe alternative to general anesthesia.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75152562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}