Saudi Journal of Medical and Pharmaceutical Sciences最新文献_第7页

Experience of Prevalence of Thyroid Carcinoma in Thyroid Swelling 甲状腺肿大中甲状腺癌发病率的经验

Saudi Journal of Medical and Pharmaceutical Sciences Pub Date : 2023-11-08 DOI: 10.36348/sjmps.2023.v09i11.003

Dr. Bashudeb Kumar Saha, Dr. I.M. Hashim, Dr. Md. Iqbal Hossen, Senior Consultant

引用次数: 0

Pterygium Recurrence Prevention Utilizing Mitomycin C Washing, Case Series 利用丝裂霉素C清洗预防翼状胬肉复发，病例系列

Saudi Journal of Medical and Pharmaceutical Sciences Pub Date : 2023-11-06 DOI: 10.36348/sjmps.2023.v09i11.002

Luis Juan, Rafael Francisco, Frida Antonio, Lucia Fernado

引用次数: 0

Antibacterial Activity of Mentha piperita (Peppermint) Oil against Wound Infections Caused by Carbapenem-Resistant Klebsiella in Rats 薄荷油对耐碳青霉烯克雷伯菌所致大鼠创面感染的抗菌作用

Saudi Journal of Medical and Pharmaceutical Sciences Pub Date : 2023-11-02 DOI: 10.36348/sjmps.2023.v09i11.001

Fahad Alturaiki, Babu Joseph, Fahad Mohammed Asad

{"title":"Antibacterial Activity of Mentha piperita (Peppermint) Oil against Wound Infections Caused by Carbapenem-Resistant Klebsiella in Rats","authors":"Fahad Alturaiki, Babu Joseph, Fahad Mohammed Asad","doi":"10.36348/sjmps.2023.v09i11.001","DOIUrl":"https://doi.org/10.36348/sjmps.2023.v09i11.001","url":null,"abstract":"Drug resistant Klebsiella pneumoniae causes nosocomial infections, pneumonia, wound sepsis and infections of newborns and intensive care patients. In many cases antibiotics are no longer very effective in patients treated for K. pneumoniae infections. Various studies have shown antimicrobial properties of essential oils and different compounds that are part of them. This study aimed to determine the antibacterial efficacy and minimum inhibitory concentration of the Mentha piperita essential oil against resistant strain of K. pneumoniae. Efficiency of peppermint oil when used with antibiotics in wound management as well as controlling K. pneumoniae infection was also investigated in this study. Well diffusion method was used to determine the antibacterial activity of peppermint oil, where its inhibitory capacity was observed along with antibiotics and compared with control. Bacterial load of K. pneumonia OXA48 resistant strain on wound in rat models was also studied and compared. Klebsiella pneumoniae OXA48 and K. pneumoniae ATCC 700603 were inhibited by effectively by 40 µl/ml of peppermint oil in well diffusion assays. In rat models the wounds were healed, and epithelization was quicker in 10% peppermint oil treated wounds. Wounds applied with a combination of peppermint oil and Imipenem were more effectively protected from infection and showed better healing as well. Peppermint oil depicted both inhibitory capacities against K. pneumonia OXA48 and promoted wound healing as well. Further studies regarding PMO and its efficacy in wound management as well as its associated molecular mechanism would provide better understanding regarding its potential.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"104 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135976041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

To Asses Maternal Morbidity and Mortality of Induced Abortion among Admitted Cases in Rajshahi Medical College Hospital, Rajshahi 评估拉杰沙希医学院医院住院病例中产妇人工流产的发病率和死亡率

Saudi Journal of Medical and Pharmaceutical Sciences Pub Date : 2023-10-31 DOI: 10.36348/sjmps.2023.v09i10.007

Marzina Khatun, Shadia Sharmin Sultana, Rehana Parven, Sharifa Begum, Mousumee Mondal

{"title":"To Asses Maternal Morbidity and Mortality of Induced Abortion among Admitted Cases in Rajshahi Medical College Hospital, Rajshahi","authors":"Marzina Khatun, Shadia Sharmin Sultana, Rehana Parven, Sharifa Begum, Mousumee Mondal","doi":"10.36348/sjmps.2023.v09i10.007","DOIUrl":"https://doi.org/10.36348/sjmps.2023.v09i10.007","url":null,"abstract":"Background: Abortion is pregnancy termination before the 24th week. Unsafe induced abortions, lacking proper skills or medical standards, cause 67,000 annual deaths in developing countries, according to WHO. Ensuring access to safe and legal abortion services is critical to reducing maternal mortality and safeguarding women's health globally. Objectives: The aim of this study was to find out maternal mortality as well as morbidity related to induce abortion for termination of unwanted pregnancy in our set up. Methods: A cross-sectional study was conducted on 92 patients who admitted as cases of induced abortion in Rajshahi Medical College Hospital from March' 2014 to September 2014Those who had given informed written consent was finally enrolled in this study. Patients' details history, clinical examination investigation, and operation note was collected in a preformed data sheet. Data was presented in the form of tables and graphs. Data was presented with descriptive statistics the level of significance of 0.05 was used for this study. Results: Among 92 patients were 15(16.3%) hemorrhage, 9(9.8%) hypovolemic shock, 10(10.9%) generalized peritonitis, 34(36.9%) pelvic peritonitis5 (5.4%) perforation of uterus, 4(4.3%) cervical injury, 1(1.1%) perforation of gut, 2(2.2%) septic shock, 2(2.2%) acute renal failure, 10(10.9%) no major complication. Among 92 patient 86 (93.5%) patients were improved and discharged and 6(6.5%) patients were expired. Conclusion: Induced abortion is a common gynecological problem requiring hospital admission and treatment. It has serious short term and long-term complications affecting women's health and life.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135977013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pneumonia Infection Incidence with Enteral Feeding in Intensive Care Patients 重症监护患者肠内喂养后肺炎感染的发生率

Saudi Journal of Medical and Pharmaceutical Sciences Pub Date : 2023-10-29 DOI: 10.36348/sjmps.2023.v09i10.006

Mashael Alharbi, Kamal K. Alsofyani, Mohammed Alshehri, Rakan Alshareef, Osama A. Alshehri, Saad Alsaad, Nuha M. Barnawi

{"title":"Pneumonia Infection Incidence with Enteral Feeding in Intensive Care Patients","authors":"Mashael Alharbi, Kamal K. Alsofyani, Mohammed Alshehri, Rakan Alshareef, Osama A. Alshehri, Saad Alsaad, Nuha M. Barnawi","doi":"10.36348/sjmps.2023.v09i10.006","DOIUrl":"https://doi.org/10.36348/sjmps.2023.v09i10.006","url":null,"abstract":"Background: Enteral nutrition (EN) is the administration of a nutritionally complete feed through a tube into the stomach, duodenum, or jejunum. It has been proposed that EN helps to maintain the health and integrity of the gut barrier and is connected to increased levels of immunoglobulin synthesis, which may help to boost defenses against respiratory infections. However, critically ill patients may have a poor tolerance for enteral feeding and may develop unpleasant gastrointestinal effects such as nausea and vomiting. Aim: To investigate at the incidence between enteral nutrition and the risk of pneumonia in intensive care unit patients. Methods: This is an updated review of research that were published between 2016 and 2018. To research our topic, we employed the Google Scholar, Web of Science, and PubMed databases. The keywords used in various combinations included \"enteral nutrition, feeding, incidence, aspiration, pneumonia, adults, ICU.\" In addition, original research on the relationship between entreat feeding and the risk of pneumonia in critically ill individuals was reviewed. The inclusion criterion was full-text publications. Results: Despite obtaining 17 papers, only three research met the inclusion requirements. All of the research were conducted in the past. The study included 413 adult patients in the intensive care unit. Conclusion: In critically ill people, enteral feeding was related with a lower risk of aspiration pneumonia and overall infections. Enteral feeding was found to be safe and effective for critically ill patients, with no major problems.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"8 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136157579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In-Silico Validation of Niazinin-A Against Proinflammatory Mediator: Anti-Proliferative Potential Niazinin-A抗促炎介质的计算机验证:抗增殖潜能

Saudi Journal of Medical and Pharmaceutical Sciences Pub Date : 2023-10-25 DOI: 10.36348/sjmps.2023.v09i10.005

Shobharam Sahu, Chhaya Rathor Sahu, Divakar Kanakagiri, Jitender Kumar Malik

{"title":"In-Silico Validation of Niazinin-A Against Proinflammatory Mediator: Anti-Proliferative Potential","authors":"Shobharam Sahu, Chhaya Rathor Sahu, Divakar Kanakagiri, Jitender Kumar Malik","doi":"10.36348/sjmps.2023.v09i10.005","DOIUrl":"https://doi.org/10.36348/sjmps.2023.v09i10.005","url":null,"abstract":"Background: Cancer is one of the most dreaded human diseases, that has become an ever-increasing health problem and is a prime cause of death globally. Munga, also known as Moringa oleifera Lam., is one of the most significant plants grown extensively in India. This plant, Moringa oleifera Lam, is used extensively as a dietary supplement and has valuable pharmacological properties including anti-asthmatic, anti-diabetic, hepatoprotective, anti-inflammatory, anti-cancer, antimicrobial, anti-oxidant, cardiovascular, anti-ulcer, CNS activity, anti-allergic, wound healing, analgesic, and antipyretic action. This plant has great therapeutic properties in every area. It is a good source of milk protein, vitamin A, and vitamin C. Alkaloids, protein, quinine, saponins, flavonoids, tannin, steroids, glycosides, fixed oil, and lipids are only a few examples of the several active phytoconstituents that are present. Aim: The current work sought to elucidate the molecular basis for Niazinin A antiproliferative activity against the VEGF-1 & AURKA, which functions as a proinflammatory factor in proliferation. Method: A molecular docking method was employed in the current work to look for VEGFR-1 & AURKA protein inhibitors. The binding was determined by the Auto Dock software utilising a grid-based docking method. Results: The molecular docking result revealed that Niazinin A showed encouraging docking score. The docking score found to be -7& -6.11 for VEGF-1 & AURKA kcal mol–1 respectively. Conclusion: The interaction of ligand hits to targeted site and docking score finding it can be predicted that Niazinin A found in the plants Moringa exhibited good inhibitor of VEGF-1 & AURKA protein.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135167290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges of Health Informatics Systems in Primary Health Care 初级卫生保健卫生信息系统的挑战

Saudi Journal of Medical and Pharmaceutical Sciences Pub Date : 2023-10-13 DOI: 10.36348/sjmps.2023.v09i10.004

Amro A. Alamro, Mohammed S. Aljuma, Sami S. Alateeq, Nader M. Alharbi, Abdulaziz S. Alharbi, Rayan S. Alghufaili, Ahmed A. Alsharekh, Abdullah A. Alharbi

{"title":"Challenges of Health Informatics Systems in Primary Health Care","authors":"Amro A. Alamro, Mohammed S. Aljuma, Sami S. Alateeq, Nader M. Alharbi, Abdulaziz S. Alharbi, Rayan S. Alghufaili, Ahmed A. Alsharekh, Abdullah A. Alharbi","doi":"10.36348/sjmps.2023.v09i10.004","DOIUrl":"https://doi.org/10.36348/sjmps.2023.v09i10.004","url":null,"abstract":"Health informatics systems are indispensable implements for cultivating the eminence and effectiveness of primary health care. Health informatics systems are formed of databases and figures regarding all clinical facilities. The utilization of health informatics systems helps both healthcare providers and patients in the management of disorders and disease risks and in developing well-being. However, there are a number of challenges to the application and practice of health informatics systems in the settings of primary health care. These challenges embrace; the absence of capital and money, the absence of technical skill, the absence of user recognition and approval, information quality problems, safety and confidentiality concerns, incorporation with other systems, and interoperability deficiency. Human, cultural, and financial barriers with deficiency of technical proficiency, deficiency of a relation between clinicians and patients, worries about information privacy, absence of administration guidelines, bureaucracy, lack of training, English language barrier, the degree of workload due to the time shortness during clinical settings, infrastructure concerns e.g. availability of the electricity, computers, and internet, also high turnover in IT among healthcare are also some challenges that should be addressed. These challenges can hold back the capacity of health informatics systems to comprehend their complete perspective in primary health care. To address these challenges, it is essential to provide sufficient capital and funds, offer practice and maintenance for users, overcome information quality concerns, apply safety and confidentiality procedures, incorporate health informatics systems with other systems, and endorse interoperability. By overcoming these challenges, health informatics systems can play a major role in developing the quality and efficiency of primary health care.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135923034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A dragging Externotitis Hiding Tuberculosis of the External Ear 外耳拖拽性隐匿性外耳炎1例

Saudi Journal of Medical and Pharmaceutical Sciences Pub Date : 2023-10-06 DOI: 10.36348/sjmps.2023.v09i10.003

N. Belhaj, R. Bencheikh, M. A. Benbouzid, L. Houssayni, Essakalli Essakalli

引用次数: 0

Scrub Typhus – An Emerging Public Health Threat in Northern India 丛林斑疹伤寒——印度北部新出现的公共卫生威胁

Saudi Journal of Medical and Pharmaceutical Sciences Pub Date : 2023-10-05 DOI: 10.36348/sjmps.2023.v09i10.002

Rahul Shil

引用次数: 0

Ascertaining the Level of Psychological Effects of Delayed Menstrual Period among Female Students in Tertiary Institutions in South-South, Nigeria 尼日利亚南南高等院校女生月经延迟的心理影响程度

Saudi Journal of Medical and Pharmaceutical Sciences Pub Date : 2023-10-02 DOI: 10.36348/sjmps.2023.v09i10.001

Gbaranor, K. B, Dickson, I. C, Okocha, A. N, Mube, W. A, Ile, V. I, Kinako, S. E, Dimkpa, B. M, Oluoha, R. U, Kue, D. S, Dimkpa, C. R, Chris-Biriowu H., George, A. F, Nwogu H. C, Pepple, B. G

{"title":"Ascertaining the Level of Psychological Effects of Delayed Menstrual Period among Female Students in Tertiary Institutions in South-South, Nigeria","authors":"Gbaranor, K. B, Dickson, I. C, Okocha, A. N, Mube, W. A, Ile, V. I, Kinako, S. E, Dimkpa, B. M, Oluoha, R. U, Kue, D. S, Dimkpa, C. R, Chris-Biriowu H., George, A. F, Nwogu H. C, Pepple, B. G","doi":"10.36348/sjmps.2023.v09i10.001","DOIUrl":"https://doi.org/10.36348/sjmps.2023.v09i10.001","url":null,"abstract":"Menstrual period is a monthly activity that every woman who has attained the age of puberty experienced. It is a natural process and when it does not show or come, the woman in question will be worried and until the root cause of the delayed or stoppage is known and if possible, rectify the cause of the abnormally, the woman will not be happy. The aim of the study is Ascertaining the Level of Psychological Effects of Delayed Menstrual Period Among Female Students in Tertiary Institutions in South South, Nigeria. The study was a cross-sectional study and a total of 250 female students within participated in the study. A well-structured questionnaire was distributed to each participant by the research assistant after consent was granted by the participants. The study was carried out in the six States that make up South-South Geopolitical Zones and it lasted for a period of 3 months. The findings revealed that 243(97.20%) of the participants affirmed being depressed as a result of delayed menstrual period while 7(2.80%) disagreed being depressed due to delayed menstrual period. Also, 240(96.00%) of the respondents isolated themselves due to delayed menstrual period. The results shows that 238(95.20%) of the respondents were ashamed due to delayed menstrual period and 239(95.60%) were deeply thinking. The research revealed that 240(96.00%) of the participants agreed that delayed menstrual period affects their academic performance and 243(97.20%) of the respondents worried about the delayed in their menstrual period. The data were analysed using SPSS version 23 and P < 0.05 was said to be significant.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135900611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0