Romanian journal of anaesthesia and intensive care最新文献

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Postanaesthetic shivering - from pathophysiology to prevention. 后美学颤抖——从病理生理学到预防。
Romanian journal of anaesthesia and intensive care Pub Date : 2018-04-01 DOI: 10.21454/rjaic.7518.251.xum
Maria Bermudez Lopez
{"title":"Postanaesthetic shivering - from pathophysiology to prevention.","authors":"Maria Bermudez Lopez","doi":"10.21454/rjaic.7518.251.xum","DOIUrl":"https://doi.org/10.21454/rjaic.7518.251.xum","url":null,"abstract":"<p><p>Postoperative shivering is a common complication of anaesthesia. Shivering is believed to increase oxygen consumption, increase the risk of hypoxemia, induce lactic acidosis, and catecholamine release. Therefore, it might increase the postoperative complications especially in high-risk patients. Moreover, shivering is one of the leading causes of discomfort for postsurgical patients. Shivering is usually triggered by hypothermia. However, it occurs even in normothermic patients during the perioperative period. The aetiology of shivering has been understood insufficiently. Another potential mechanism is pain and acute opioid withdrawal (especially with the use of short-acting narcotics). Besides that shivering is poorly understood, the gold standard for the treatment and prevention has not been defined yet. Perioperative hypothermia prevention is the first method to avoid shivering. Many therapeutic strategies for treating shivering exist and most are empiric. Unfortunately, the overall quality of the antishivering guidelines is low. Two main strategies are available: pharmacological and non-pharmacological antishivering methods. The combination of forced-air warming devices and intravenous meperidine is the most validated method. We also analysed different medications but final conclusion about the optimal antishivering medication is difficult to be drawn due to the lack of high-quality evidence. Nevertheless, control of PS is possible and clinically effective with simple pharmacological interventions combined with non pharmacological methods. However, to be consistent with the most up-to-date, evidence-based practice, future antishivering treatment protocols should optimize methodological rigor and transparency.</p>","PeriodicalId":21279,"journal":{"name":"Romanian journal of anaesthesia and intensive care","volume":"25 1","pages":"73-81"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.21454/rjaic.7518.251.xum","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36095001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 69
Factors associated with acute and chronic pain after inguinal herniorraphy. 腹股沟疝切开术后急性和慢性疼痛的相关因素。
Romanian journal of anaesthesia and intensive care Pub Date : 2018-04-01 DOI: 10.21454/rjaic.7518.251.oze
Elif Erdogan, Ecder Ozenc
{"title":"Factors associated with acute and chronic pain after inguinal herniorraphy.","authors":"Elif Erdogan,&nbsp;Ecder Ozenc","doi":"10.21454/rjaic.7518.251.oze","DOIUrl":"https://doi.org/10.21454/rjaic.7518.251.oze","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to analyse the relationship between types of anaesthesia, patients' demographic variables, preoperative emotional states and the prevalence of postoperative pain.</p><p><strong>Method: </strong>In this randomized prospective study, postoperative pain was assessed in 100 patients, who were ASA (American Society of Anaesthesiologist) I-II and between 18-65 years old, undergoing inguinal herniorrhaphy with either general or spinal anaesthesia. In addition, postoperative pain compared with patients' demographic properties and psychological conditions in each group was also considered. Acute pain was evaluated at 1, 2, 4, 6, 12 and 24<sup>th</sup> hours with the Numerical Rating Scale (NRS) and chronic neuropathic pain was at 1, 2 and 3<sup>rd</sup> months with Douleur Neuropathique 4 Questions (DN4). All patients were treated with the same analgesics after operation.</p><p><strong>Results: </strong>Group spinal anaesthesia had lower acute pain at 1 and 2<sup>nd</sup> hours but they felt more severe pain at the 24<sup>th</sup> hour. Also patients' anxieties were correlated with acute and chronic postoperative pain. Ten patients complained about postoperative chronic pain after 3 months and there was no significant difference between groups.</p><p><strong>Conclusion: </strong>Spinal anaesthesia decreased acute pain intensity at the first postoperative hours. Patients with anxiety felt high pain levels and they had an increased chronic pain prevalence.</p>","PeriodicalId":21279,"journal":{"name":"Romanian journal of anaesthesia and intensive care","volume":"25 1","pages":"31-35"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.21454/rjaic.7518.251.oze","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36095059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Effect of preoperative gabapentin and acetaminophen on opioid consumption in video-assisted thoracoscopic surgery: a retrospective study. 术前加巴喷丁和对乙酰氨基酚对视频胸腔镜手术中阿片类药物消耗的影响:一项回顾性研究。
Romanian journal of anaesthesia and intensive care Pub Date : 2018-04-01 DOI: 10.21454/rjaic.7518.251.gab
Robert Qiu, Albert C Perrino, Holly Zurich, Nitin Sukumar, Feng Dai, Wanda Popescu
{"title":"Effect of preoperative gabapentin and acetaminophen on opioid consumption in video-assisted thoracoscopic surgery: a retrospective study.","authors":"Robert Qiu,&nbsp;Albert C Perrino,&nbsp;Holly Zurich,&nbsp;Nitin Sukumar,&nbsp;Feng Dai,&nbsp;Wanda Popescu","doi":"10.21454/rjaic.7518.251.gab","DOIUrl":"https://doi.org/10.21454/rjaic.7518.251.gab","url":null,"abstract":"<p><strong>Background: </strong>Patients undergoing video-assisted thoracoscopic surgery (VATS) are particularly vulnerable to opioid-induced sedation and hypoventilation. Accordingly, reducing opioid consumption in these patients is a primary goal of multimodal analgesic regimens. Although administration of preoperative gabapentin and acetaminophen has been shown to decrease postoperative opioid consumption in other surgeries, this approach has not been studied in VATS lobectomy. Our objective was to examine the impact of the addition of preoperative gabapentin and acetaminophen to a VATS lobectomy multimodal analgesic plan on postoperative opioid consumption, nausea/vomiting, and sedation.</p><p><strong>Methods: </strong>With IRB approval, we performed a retrospective chart review of patients who underwent VATS lobectomy at a single center between 2015 and 2016 to identify those that received preoperative gabapentin and acetaminophen and those that received neither. Opioid consumption in the first 24 hours postoperatively was converted to oral morphine equivalents (OMEQs). Postoperative sedation was evaluated using Aldrete scores and the percentage of patients requiring antiemetics in the first 24 hours was also examined.</p><p><strong>Results: </strong>There were 133 patients who were opioid naive: 31 received preoperative gabapentin and acetaminophen and 102 received neither. Median 24 hour postoperative opioid consumption was lower but not statistically significant in the gabapentin and acetaminophen group vs. neither (36 mg vs. 45 mg, p = 0.08). Notably, there was a change in the distribution of opioid consumption, with no patients in the gabapentin and acetaminophen group requiring more than 200 mg OMEQ in the first 24 hours postoperatively. No significant difference in postoperative nausea/vomiting or sedation was observed.</p><p><strong>Conclusions: </strong>The addition of preoperative gabapentin and acetaminophen to a VATS lobectomy multimodal analgesic regimen reduces the incidence of high dose postoperative opioid consumption without observed negative side effects.</p>","PeriodicalId":21279,"journal":{"name":"Romanian journal of anaesthesia and intensive care","volume":"25 1","pages":"43-48"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931182/pdf/rjaic-25-1-43.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36094996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Neuromuscular monitoring: an update. 神经肌肉监测:最新进展。
Romanian journal of anaesthesia and intensive care Pub Date : 2018-04-01 DOI: 10.21454/rjaic.7518.251.nrm
Mădălina Duţu, Robert Ivaşcu, Oana Tudorache, Darius Morlova, Alina Stanca, Silvius Negoiţă, Dan Corneci
{"title":"Neuromuscular monitoring: an update.","authors":"Mădălina Duţu, Robert Ivaşcu, Oana Tudorache, Darius Morlova, Alina Stanca, Silvius Negoiţă, Dan Corneci","doi":"10.21454/rjaic.7518.251.nrm","DOIUrl":"10.21454/rjaic.7518.251.nrm","url":null,"abstract":"<p><p>This review makes an advocacy for neuromuscular blockade monitoring during anaesthesia care, by: (i) describing the fundamental principles of the methods currently available, at the same time emphasizing quantitative recording measurements; (ii) describing the different ways in which muscles respond to the effect of neuromuscular blockade and their use in clinical practice; (iii) presenting results of different studies on timing and agents of neuromuscular block reversal, including a recommendation for sugammadex use and experimental results with calabadion and (iv) in the end emphasizing the need for implementing neuromuscular monitoring as a practice that should be used every time a neuromuscular block is required.</p>","PeriodicalId":21279,"journal":{"name":"Romanian journal of anaesthesia and intensive care","volume":"25 1","pages":"55-60"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931185/pdf/rjaic-25-1-55.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36094998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Right Author in the Right Journal at the Right Time: future perspectives. 正确的作者,正确的期刊,正确的时间:未来的观点。
Romanian journal of anaesthesia and intensive care Pub Date : 2018-04-01 DOI: 10.21454/rjaic.7518.251.rat
Dorel Săndesc
{"title":"The Right Author in the Right Journal at the Right Time: future perspectives.","authors":"Dorel Săndesc","doi":"10.21454/rjaic.7518.251.rat","DOIUrl":"https://doi.org/10.21454/rjaic.7518.251.rat","url":null,"abstract":"","PeriodicalId":21279,"journal":{"name":"Romanian journal of anaesthesia and intensive care","volume":"25 1","pages":"5-6"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931184/pdf/rjaic-25-1-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36095053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spring recoil and supraglottic airway devices: lessons from the law of conservation of energy. 弹簧反冲与声门上气道装置:能量守恒定律的启示。
Romanian journal of anaesthesia and intensive care Pub Date : 2018-04-01 DOI: 10.21454/rjaic.7518.251.sor
Massimiliano Sorbello, Ivana Zdravkovic, Rita Cataldo, Ida Di Giacinto
{"title":"Spring recoil and supraglottic airway devices: lessons from the law of conservation of energy.","authors":"Massimiliano Sorbello, Ivana Zdravkovic, Rita Cataldo, Ida Di Giacinto","doi":"10.21454/rjaic.7518.251.sor","DOIUrl":"10.21454/rjaic.7518.251.sor","url":null,"abstract":"","PeriodicalId":21279,"journal":{"name":"Romanian journal of anaesthesia and intensive care","volume":"25 1","pages":"7-9"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931187/pdf/rjaic-25-1-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36095055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effects of mechanical ventilation on the quality of sleep of hospitalised patients in the Intensive Care Unit. 机械通气对重症监护病房住院患者睡眠质量的影响
Romanian journal of anaesthesia and intensive care Pub Date : 2018-04-01 DOI: 10.21454/rjaic.7518.251.ven
Hana Locihová, Katarína Žiaková
{"title":"The effects of mechanical ventilation on the quality of sleep of hospitalised patients in the Intensive Care Unit.","authors":"Hana Locihová,&nbsp;Katarína Žiaková","doi":"10.21454/rjaic.7518.251.ven","DOIUrl":"https://doi.org/10.21454/rjaic.7518.251.ven","url":null,"abstract":"<p><strong>Aim: </strong>To examine the effects of mechanical ventilation on the quality of sleep in patients in the intensive care unit (ICU) using recent and relevant literature.</p><p><strong>Methods: </strong>To verify the examined objective, the results of the analysis of available original scientific works have been used including defined inclusion/exclusion criteria and search strategy. Appropriate works found were analysed further. The applied methodology was in line with the general principles of Evidence-Based Medicine. The following literary databases were used: CINAHL, Medline and gray literature: Google Scholar.</p><p><strong>Results: </strong>A total of 91 trials were found. Eleven of these relevant to the follow-up analysis were selected: all trials were carried out under real ICU conditions and the total of 192 patients were included in the review. There is an agreement within all trials that sleep in patients requiring mechanical ventilation is disturbed. Most reviewed trials have shown that mechanical ventilation is probably not the main factor causing sleep disturbances, but an appropriate ventilation strategy can significantly help to improve its quality by reducing the frequency of the patient-ventilator asynchrony.</p><p><strong>Conclusion: </strong>Based on the analysis, it appears that an appropriate ventilation mode setting can have a beneficial effect on the quality of sleep in ICU patients.</p>","PeriodicalId":21279,"journal":{"name":"Romanian journal of anaesthesia and intensive care","volume":"25 1","pages":"61-72"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931186/pdf/rjaic-25-1-61.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36094999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Concurrent intraoperative uterine rupture and placenta accreta. Do preoperative chronic hypertension, preterm premature rupture of membranes, chorioamnionitis, and placental abruption provide warning to this rare occurrence? 术中并发子宫破裂和胎盘增生。术前慢性高血压、胎膜早破、绒毛膜羊膜炎和胎盘早剥是否为这种罕见的情况提供了警告?
Romanian journal of anaesthesia and intensive care Pub Date : 2018-04-01 DOI: 10.21454/rjaic.7518.251.acc
M Anthony Cometa, Scott M Wasilko, Adam L Wendling
{"title":"Concurrent intraoperative uterine rupture and placenta accreta. Do preoperative chronic hypertension, preterm premature rupture of membranes, chorioamnionitis, and placental abruption provide warning to this rare occurrence?","authors":"M Anthony Cometa,&nbsp;Scott M Wasilko,&nbsp;Adam L Wendling","doi":"10.21454/rjaic.7518.251.acc","DOIUrl":"https://doi.org/10.21454/rjaic.7518.251.acc","url":null,"abstract":"<p><p>Uterine and placental pathology can be a major cause of morbidity and mortality in the parturient and infant. When presenting alone, placental abruption, uterine rupture, or placenta accreta can result in significant peripartum hemorrhage, requiring aggressive surgical and anesthetic management; however, the presence of multiple concurrent uterine and placental pathologies can result in significant morbidity and mortality. We present the anesthetic management of a parturient who underwent an urgent cesarean delivery for non-reassuring fetal tracing in the setting of chronic hypertension, preterm premature rupture of membranes, and chorioamnionitis who was subsequently found to have placental abruption, uterine rupture, and placenta accreta.</p>","PeriodicalId":21279,"journal":{"name":"Romanian journal of anaesthesia and intensive care","volume":"25 1","pages":"83-85"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931189/pdf/rjaic-25-1-83.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36095000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical application of limiting laryngeal mask airway cuff pressures utilizing inflating syringe intrinsic recoil. 利用充气注射器内在反冲力限制喉罩气道充气罩囊压力的临床应用。
Romanian journal of anaesthesia and intensive care Pub Date : 2018-04-01 DOI: 10.21454/rjaic.7518.251.cuf
David M Corda, Christopher B Robards, Mark J Rice, Timothy E Morey, Nikolaus Gravenstein, Terrie Vasilopoulos, Sorin J Brull
{"title":"Clinical application of limiting laryngeal mask airway cuff pressures utilizing inflating syringe intrinsic recoil.","authors":"David M Corda, Christopher B Robards, Mark J Rice, Timothy E Morey, Nikolaus Gravenstein, Terrie Vasilopoulos, Sorin J Brull","doi":"10.21454/rjaic.7518.251.cuf","DOIUrl":"10.21454/rjaic.7518.251.cuf","url":null,"abstract":"<p><strong>Background: </strong>Overinflation of the laryngeal mask airway (LMA) cuff may cause many of the complications associated with the use of the LMA. There is no clinically acceptable (cost effective and practical) method to ensure cuff pressure is maintained below the manufacturer's recommended maximum value of 60 cm H<sub>2</sub>O (44 mmHg). We studied the use of the intrinsic recoil of the LMA inflating syringe as an effective and practical way to limit cuff pressures at or below the manufacturer's recommended values.</p><p><strong>Methods: </strong>We enrolled 332 patients into three separate groups: LMAs inserted and inflated per standard practice at the institution with only manual palpation of the pilot balloon; LMA cuff pressures measured by a pressure transducer and reduced to < 60 cm H<sub>2</sub>O (44 mmHg); and LMA intra-cuff pressure managed by the intrinsic recoil of the syringe.</p><p><strong>Results: </strong>There were no statistically significant differences between the pressure transducer group and the syringe recoil group for initial cuff pressure or cuff pressure 1 hour after surgery. Both the syringe recoil group and pressure transducer group were less likely than the standard practice group to have sore throat and dysphagia 1 hour after surgery. These differences remained 24 hours after surgery.</p><p><strong>Conclusions: </strong>Syringe recoil provides an efficient and reproducible method similar to manometry in preventing overinflation of the LMA cuff and decreasing the incidence of postoperative laryngopharyngeal complications.</p>","PeriodicalId":21279,"journal":{"name":"Romanian journal of anaesthesia and intensive care","volume":"25 1","pages":"11-18"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931177/pdf/rjaic-25-1-11.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36095056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pupillary dilation reflex and pupillary pain index evaluation during general anaesthesia: a pilot study. 全麻期间瞳孔扩张反射和瞳孔疼痛指数评估:一项初步研究。
Romanian journal of anaesthesia and intensive care Pub Date : 2018-04-01 DOI: 10.21454/rjaic.7518.251.wil
Davina Wildemeersch, Michiel Baeten, Natasja Peeters, Vera Saldien, Marcel Vercauteren, Guy Hans
{"title":"Pupillary dilation reflex and pupillary pain index evaluation during general anaesthesia: a pilot study.","authors":"Davina Wildemeersch,&nbsp;Michiel Baeten,&nbsp;Natasja Peeters,&nbsp;Vera Saldien,&nbsp;Marcel Vercauteren,&nbsp;Guy Hans","doi":"10.21454/rjaic.7518.251.wil","DOIUrl":"https://doi.org/10.21454/rjaic.7518.251.wil","url":null,"abstract":"<p><strong>Background: </strong>Pupillary response by pupillary dilatation reflex (PDR) is a robust reflex, even measurable during general anaesthesia. However, the ability of infrared pupillometry to detect PDR differences obtained by intraoperative opioid administration in anaesthesized patients remains largely unknown. We analyzed the performance of automated infrared pupillometry in detecting differences in pupillary dilatation reflex response by a inbuilt standardized nociceptive stimulation program in patients under general anesthesia with a standardized propofol/fentanyl scheme.</p><p><strong>Methods: </strong>In this single center, interventional cohort study 38 patients (24-74 years) were enrolled. Patients were anesthetized with propofol until loss of consciousness. Two dynamic pupil measurements were performed in each patient (before opioid administration and after opioid steady state). Automated infrared pupillometry was used to determine PDR during nociceptive stimulations (10-60 mA) applied by a inbuilt pupillary pain index protocol (PPI) to the skin area innervated by the median nerve. Increasing stimulations by protocol are device specific and automatically performed until pupil dilation of > 13%. Pupil characteristics, blood pressure, heart rate values were collected.</p><p><strong>Results: </strong>After opioid administration, patients needed a higher stimulation intensity (45.26 mA vs 30.79 mA, p = 0.00001). PPI score showed a reduction after analgesic treatment (5.21 vs 7.68, p = 0.000001), resulting in a 32.16% score reduction.</p><p><strong>Conclusions: </strong>PDR via automated increased tetanic stimulation may reflect opioid effect under general anaesthesia<i>.</i> Further research is required to detect possible confounding factors such as medication interaction and optimization of individualized opioid dosage.</p>","PeriodicalId":21279,"journal":{"name":"Romanian journal of anaesthesia and intensive care","volume":"25 1","pages":"19-23"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.21454/rjaic.7518.251.wil","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36095057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
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