Revista Brasileira de Hematologia e Hemoterapia最新文献

{"title":"Patient posture for blood collection by venipuncture: recall for standardization after 28 years","authors":"Gabriel Lima-Oliveira,&nbsp;Gian Cesare Guidi,&nbsp;Gian Luca Salvagno,&nbsp;Elisa Danese,&nbsp;Martina Montagnana,&nbsp;Giuseppe Lippi","doi":"10.1016/j.bjhh.2017.01.004","DOIUrl":"10.1016/j.bjhh.2017.01.004","url":null,"abstract":"<div><h3>Background</h3><p>Although data about the effect of posture on routine hematological testing were published 28 years ago, this pre-analytical issue has not been standardized so far. This study was planned to evaluate whether postural changes influence the results of hematology testing.</p></div><div><h3>Methods</h3><p>A complete blood count was performed in 19 healthy volunteers after 25<!--> <!-->min in the supine position, 20<!--> <!-->min in a sitting position and 20<!--> <!-->min stationary standing in an upright position.</p></div><div><h3>Results</h3><p>The change from supine to sitting position caused clinically significant increases in the hemoglobin, hematocrit and red blood cell count. Furthermore, the change from supine to standing caused clinically significant increases in the hemoglobin, hematocrit, red blood cell, leukocyte, neutrophil, lymphocyte, basophil and platelet counts, and mean platelet volume, and that from sitting to standing caused clinically significant increases in hemoglobin, hematocrit, and red blood cell, leukocyte, neutrophil and lymphocyte counts.</p></div><div><h3>Conclusion</h3><p>The results of this investigation provide further support to the notion that effort should be made to achieve widespread standardization in the practice of phlebotomy, including patient posture.</p></div>","PeriodicalId":21233,"journal":{"name":"Revista Brasileira de Hematologia e Hemoterapia","volume":"39 2","pages":"Pages 127-132"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bjhh.2017.01.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35057145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum to “Alloimmunization screening after transfusion of red blood cells in a prospective study” [Rev Bras Hematol Hemoter. 2012;34(3):206–211]","authors":"Vitor Mendonça Alves ,&nbsp;Paulo Roberto Juliano Martins ,&nbsp;Sheila Soares ,&nbsp;Gislene Araújo ,&nbsp;Luciana Cayres Schmidt ,&nbsp;Sidneia Sanches de Menezes Costa ,&nbsp;Dante Mário Langhid ,&nbsp;Helio Moraes-Souza","doi":"10.1016/j.bjhh.2017.04.001","DOIUrl":"10.1016/j.bjhh.2017.04.001","url":null,"abstract":"","PeriodicalId":21233,"journal":{"name":"Revista Brasileira de Hematologia e Hemoterapia","volume":"39 2","pages":"Page 186"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bjhh.2017.04.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35056636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical activity level and performance in the six-minute walk test of children and adolescents with sickle cell anemia","authors":"Hugo Nivaldo Melo ,&nbsp;Simone Joanna-Maria Stoots ,&nbsp;Marijn Aimee Pool ,&nbsp;Vitor Oliveira Carvalho ,&nbsp;Lucas Oliveira Carvalho Almeida ,&nbsp;Max Luan De Carvalho Aragão ,&nbsp;Charles Agyemang ,&nbsp;Rosana Cipolotti","doi":"10.1016/j.bjhh.2017.02.009","DOIUrl":"10.1016/j.bjhh.2017.02.009","url":null,"abstract":"<div><h3>Background</h3><p>To establish determinants of maximum walking distance in the 6-minute walk test of children and adolescents with sickle cell anemia, and to compare the performance in this test with physical activity level between patients and healthy controls.</p></div><div><h3>Methods</h3><p>A cross-sectional study was performed in which the participants answered the Physical Activity Questionnaire for Older Children and Adolescents, and completed the 6-minute walk test.</p></div><div><h3>Main results</h3><p>Fifty-seven patients and 58 controls were studied. By univariate analysis of the patients, age (<em>p</em> <!-->&lt;<!--> <!-->0.0001) and indirect bilirubin (<em>p</em> <!-->=<!--> <!-->0.008) were associated with maximum walking distance in the 6-minute walk test. In multivariate analysis, age was positively associated (<em>p</em> <!-->&lt;<!--> <!-->0.0001; beta: 0.75), while body mass index was inversely associated with distance walked (<em>p</em> <!-->=<!--> <!-->0.047; beta: −0.32). This yields the following equation: maximum distance walked<!--> <!-->=<!--> <!-->487.7 (age<!--> <!-->×<!--> <!-->18.3)<!--> <!-->−<!--> <!-->(12<!--> <!-->×<!--> <!-->body mass index) meters. Patients reported a lower physical activity level however there was no significant difference in the distance walked in six minutes between patients (500.6<!--> <!-->±<!--> <!-->88.7<!--> <!-->m) and controls (536.3<!--> <!-->±<!--> <!-->94<!--> <!-->m).</p></div><div><h3>Conclusion</h3><p>The determinants for the 6-minute walk test in children and adolescents with sickle cell anemia were age and body mass index. There was no significant difference in the 6-minute walk test but patients with sickle cell anemia had a lower physical activity level compared to healthy controls.</p></div>","PeriodicalId":21233,"journal":{"name":"Revista Brasileira de Hematologia e Hemoterapia","volume":"39 2","pages":"Pages 133-139"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bjhh.2017.02.009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35057146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Telomere length correlates with disease severity and inflammation in sickle cell disease","authors":"Marina Pereira Colella ,&nbsp;Barbara A. Santana ,&nbsp;Nicola Conran ,&nbsp;Vinicius Tomazini ,&nbsp;Fernando F. Costa ,&nbsp;Rodrigo T. Calado ,&nbsp;Sara T. Olalla Saad","doi":"10.1016/j.bjhh.2017.02.007","DOIUrl":"10.1016/j.bjhh.2017.02.007","url":null,"abstract":"<div><h3>Background</h3><p>Telomeres, the ends of linear chromosomes, shorten during mitotic cell division and erosion may be aggravated by inflammation or proliferative and oxidative stress. As the bone marrow is under hyperproliferative pressure in sickle cell disease and several tissues are submitted to chronic inflammation, this study sought to determine the telomere length of patients with sickle cell disease.</p></div><div><h3>Methods</h3><p>The mean telomere length was measured in peripheral blood leukocytes by quantitative polymerase chain reaction. The age-adjusted telomere to single copy gene ratio was compared between 91 adult sickle cell disease patients and 188 controls.</p></div><div><h3>Results</h3><p>Sickle cell disease patients had significantly shorter telomeres than the controls (<em>p</em>-value<!--> <!-->&lt;<!--> <!-->0.0001). Moreover, among sickle cell disease genotypes, Hb SS patients had significantly shorter telomeres compared to Hb SC and Hb Sβ patients (<em>p</em>-value<!--> <!-->&lt;<!--> <!-->0.0001). Patients on hydroxyurea also had shorter telomeres in comparison to those off the drug (<em>p</em>-value<!--> <!-->=<!--> <!-->0.02). A positive correlation was observed between telomere length and hemoglobin level (<em>r</em> <!-->=<!--> <!-->0.3; <em>p</em>-value<!--> <!-->=<!--> <!-->0.004), whereas negative correlations were detected between telomere length and lymphocyte count (<em>r</em> <!-->=<!--> <!-->−0.3; <em>p</em>-value<!--> <!-->=<!--> <!-->0.005) and interleukin-8 serum levels (<em>r</em> <!-->=<!--> <!-->−0.4; <em>p</em>-value<!--> <!-->=<!--> <!-->0.02).</p></div><div><h3>Conclusions</h3><p>The findings of this study indicate that telomeres are short in sickle cell disease patients and that telomere erosion directly correlates with disease genotype, inflammation markers, and the use of hydroxyurea.</p></div>","PeriodicalId":21233,"journal":{"name":"Revista Brasileira de Hematologia e Hemoterapia","volume":"39 2","pages":"Pages 140-145"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bjhh.2017.02.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35057147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Splenic marginal zone lymphoma: a literature review of diagnostic and therapeutic challenges","authors":"Tayse Silva dos Santos,&nbsp;Renato Sampaio Tavares,&nbsp;Danielle Leão Cordeiro de Farias","doi":"10.1016/j.bjhh.2016.09.014","DOIUrl":"10.1016/j.bjhh.2016.09.014","url":null,"abstract":"<div><p>Splenic marginal zone lymphoma (SMZL) is a low-grade B-cell non-Hodgkin's lymphoma characterized by massive splenomegaly, moderate lymphocytosis with or without villous lymphocytes, rare involvement of peripheral lymph nodes and indolent clinical course. As a rare disease, with no randomized prospective trials, there is no standard of care for SMZL so far. Splenectomy has been done for many years as an attempt to control disease, but nowadays it has not been encouraged as first line because of new advances in therapy as rituximab, that are as effective with minimal toxicity. Facing these controversies, this review highlights advances in the literature regarding diagnosis, prognostic factors, treatment indications and therapeutic options.</p></div>","PeriodicalId":21233,"journal":{"name":"Revista Brasileira de Hematologia e Hemoterapia","volume":"39 2","pages":"Pages 146-154"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bjhh.2016.09.014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35056625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bone marrow transplant donor recruitment strategies to maximize, optimize, and equalize recipient chances of an acceptable match","authors":"Luís Cristóvão Porto","doi":"10.1016/j.bjhh.2016.12.002","DOIUrl":"10.1016/j.bjhh.2016.12.002","url":null,"abstract":"","PeriodicalId":21233,"journal":{"name":"Revista Brasileira de Hematologia e Hemoterapia","volume":"39 2","pages":"Pages 177-179"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bjhh.2016.12.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35056631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human platelet antigens and primary immune thrombocytopenia","authors":"Vagner Castro","doi":"10.1016/j.bjhh.2017.02.008","DOIUrl":"10.1016/j.bjhh.2017.02.008","url":null,"abstract":"","PeriodicalId":21233,"journal":{"name":"Revista Brasileira de Hematologia e Hemoterapia","volume":"39 2","pages":"Pages 95-97"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bjhh.2017.02.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35056635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stressed ends: telomere attrition in chronic diseases","authors":"Wilson Chun Fok,&nbsp;Luis Francisco Zirnberger Batista","doi":"10.1016/j.bjhh.2017.03.004","DOIUrl":"10.1016/j.bjhh.2017.03.004","url":null,"abstract":"","PeriodicalId":21233,"journal":{"name":"Revista Brasileira de Hematologia e Hemoterapia","volume":"39 2","pages":"Pages 98-99"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bjhh.2017.03.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35056637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral lesions associated with Fanconi anemia","authors":"Eric T. Stoopler,&nbsp;Lujain Homeida,&nbsp;Thomas P. Sollecito","doi":"10.1016/j.bjhh.2017.03.003","DOIUrl":"10.1016/j.bjhh.2017.03.003","url":null,"abstract":"","PeriodicalId":21233,"journal":{"name":"Revista Brasileira de Hematologia e Hemoterapia","volume":"39 2","pages":"Pages 175-176"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bjhh.2017.03.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35056630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tides within ourselves: how posture can affect blood volume, blood cells and clinical reasoning","authors":"Erich Vinicius De Paula","doi":"10.1016/j.bjhh.2017.03.007","DOIUrl":"10.1016/j.bjhh.2017.03.007","url":null,"abstract":"","PeriodicalId":21233,"journal":{"name":"Revista Brasileira de Hematologia e Hemoterapia","volume":"39 2","pages":"Pages 100-101"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bjhh.2017.03.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35057140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}