One Health & Implementation Research最新文献

{"title":"A new scoring system for operational indicators guiding leprosy monitoring and surveillance in Brazil","authors":"Ferreira Anderson Fuentes, Heukelbach Jorg, Souza Eliana Amorim de, García Gabriela Soledad Márdero, Filha Carmelita Ribeiro, Braga José Ueleres, Oliveira Maria Leide Wan-Del-Rey, Reis Adriana da Silva dos, Corona Francesco, Neto Sebastião Alves de Sena, Andrade Elaine Silva Nascimento, Andrade Thainá Isabel Bessa de, Jr Alberto Novaes Ramos","doi":"10.20517/ohir.2021.09","DOIUrl":"https://doi.org/10.20517/ohir.2021.09","url":null,"abstract":"Objective: We aimed to develop a new score to facilitate and enhance the quantitative assessment of operational standard indicators guiding leprosy monitoring and surveillance, based on data from Brazilian hyperendemic regions, 2004-2019. Methods: We analyzed epidemiological and operational standard indicators of leprosy control from the database of the Notifiable Diseases Information System in Brazil’s North and Northeast regions. The so-called IntegraHans Operational Score (IHOS) was generated, integrating 10 indicators, with a final semi-quantitative score varying from 0 (worst scenario) to 1 (best scenario). We then applied the IHOS within an ecological and population-based study to assess temporal and spatial leprosy distributions from 2004 to 2019. Results: In total, 343,888 new leprosy cases were analyzed (61% of cases in the country). There was a significant temporal trend of the IHOS annual percentage change [-0.3; 95% confidence interval (CI): -0.5 to 0.0] during 2010-2019, with large cities showing a worsening trend (average annual percentage change -0.8, 95%CI: -1.1 to -0.4). After 2010, municipalities with low and medium social vulnerability, and those with medium human development and medium and high social prosperity, showed improved IHOS scores. Spatial patterns with the best IHOS scenarios were observed in the states of Rondônia, Tocantins, and Pernambuco. Conclusion: The IHOS combines different operational parameters and is an effective and simple tool to assess leprosy control programs in Brazil. The worst IHOS scores over time were identified in critical areas, such as large cities in hyperendemic areas and municipalities with lower endemicity.","PeriodicalId":211706,"journal":{"name":"One Health & Implementation Research","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122656647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of a global training program in One Health communication","authors":"D. Thomson, Doris Ma, Patrick R. Lennard, Maurizio Ferri","doi":"10.20517/ohir.2023.12","DOIUrl":"https://doi.org/10.20517/ohir.2023.12","url":null,"abstract":"Aim: A global Train-the-Trainer Program, focused on improving the communication techniques of One Health advocates, is assessed and evaluated in this study. Methods: Between November 2020 and November 2022, a Train-the-Trainer Program engaged 1.583 trainees from 98 countries between the ages of 18 and 74. Trainees practiced public speaking by teaching a lesson about One Health in mostly underserved primary school classrooms. Two surveys of trainees (n = 222 and 203) assessed the impact of the Program’s orientation session on their confidence in science communication to a novice audience. The classroom teacher survey (n = 184 teachers, representing 4.109 students) measured the trainee’s impact at the community level during and following the lesson. Results: The Program significantly improved the trainee’s confidence in communicating science (0.1 scale points) and teaching novice audiences (0.3 scale points) about One Health. Trainees cultivated student interest in One Health [median = 9 (7.3, 10)] and 90.8% of responding classroom teachers reported a desire to continue teaching about One Health after the trainee’s lesson, 99.1% noted a post-lesson increase in student interest in science, and 97.4% recommended this lesson to their colleagues. Conclusion: This study was the first to evaluate an extensive One Health-focused communication program finding the model effective for trainees and communities alike. The trainees, through public speaking, active teaching and engaging mostly primary school students, mainstreamed One Health and inspired action in communities. The classroom teachers benefited by learning about One Health and gained a desire to share this new knowledge with others in their community.","PeriodicalId":211706,"journal":{"name":"One Health & Implementation Research","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114777237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lessons learned from the history of rabies vaccination in Colombia using the one health approach","authors":"Natalia Cediel-Becerra, R. Collins, D. Restrepo, M. C. Pardo, L. Polo, L. C. Villamil","doi":"10.20517/ohir.2023.01","DOIUrl":"https://doi.org/10.20517/ohir.2023.01","url":null,"abstract":"Canine and human rabies vaccination in Colombia began at the National Institute of Health in the second decade of the 20th century. The National Veterinary School (the National University of Colombia) also contributed to the vaccination and diagnosis of canines, in addition to the diagnosis of rabies in wildlife. A combination of international cooperation and, from the 1960s onwards, increased funding of several national institutions to support the production of animal vaccines served to further progress rabies research, vaccination campaigns and diagnosis in Colombia. The country’s success in controlling canine-transmitted rabies, resulting in an approximately 90% reduction in national human rabies cases, was recognised throughout the Americas; consequently, the activities were modelled in other nations of the region. Additionally, the Ministry of Health played a key role in controlling bovine outbreaks to minimise infection risk in animal carcasses for human consumption in northern Colombia. However, in 2000, the public laboratories for vaccine production for humans and animals were closed, creating a gap in cost-effective disease control strategies in the country. In reviewing the history of rabies control in Colombia through a One Health approach, we present some lessons learned and propose improvements for the country’s long-term rabies vaccination programmes through the integration of human and animal (both domestic and wild) activities in vaccine production and roll-out. Furthermore, we highlight the importance of engaging various government, academic, private, non-government agencies and general public stakeholders in rabies control and prevention programs, especially those in remote rural settings. Finally, we present a proposal to create the national One Health Strategic Action Plan to support the operationalization of a cross-sectoral integrated zoonoses control programme in Colombia.","PeriodicalId":211706,"journal":{"name":"One Health & Implementation Research","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133387370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use and applicability of Internet search queries for infectious disease surveillance in low- to middle-income countries","authors":"J. Beckhaus, H. Becher, M. Belau","doi":"10.20517/ohir.2022.01","DOIUrl":"https://doi.org/10.20517/ohir.2022.01","url":null,"abstract":"Uncontrolled outbreaks of emerging infectious diseases can pose threats to livelihoods and can undo years of progress made in developing regions, such as Sub-Saharan Africa. Therefore, the surveillance and early outbreak detection of infectious diseases, e.g., Dengue fever, is crucial. As a low-cost and timely source, Internet search queries data [e.g., Google Trends data (GTD)] are used and applied in epidemiological surveillance. This review aims to identify and evaluate relevant studies that used GTD in prediction models for epidemiological surveillance purposes regarding emerging infectious diseases. A comprehensive literature search in PubMed/MEDLINE was carried out, using relevant keywords identified from up-to-date literature and restricted to low- to middle-income countries. Eight studies were identified and included in the current review. Three focused on Dengue fever, three analyzed Zika virus infections, and two were about COVID-19. All studies investigated the correlation between GTD and the cases of the respective infectious disease; five studies used additional (time series) regression analyses to investigate the temporal relation. Overall, the reported positive correlations were high for Zika virus (0.75-0.99) or Dengue fever (0.87-0.94) with GTD, but not for COVID-19 (-0.81 to 0.003). Although the use of GTD appeared effective for infectious disease surveillance in low- to middle-income countries, further research is needed. The low costs and availability remain promising for future surveillance systems in low- to middle-income countries, but there is an urgent need for a standard methodological framework for the use and application of GTD.","PeriodicalId":211706,"journal":{"name":"One Health & Implementation Research","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122703523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of multisectoral collaboration in implementation of One Health Approach for control of zoonoses in Kisumu, Kenya","authors":"Nobert D. Onyango, D. Onguru, Ochung’ Angeline Atieno","doi":"10.20517/ohir.2022.29","DOIUrl":"https://doi.org/10.20517/ohir.2022.29","url":null,"abstract":"Aim: One health (OH) integrates the efforts of multiple disciplines working locally, nationally, and globally to achieve optimal health for people, animals, and the environment. Changing interactions between people, animals, plants, and the environment have resulted in the growth and expansion of human populations into new geographic areas. The proximity to domestic and wild animals, climate changes, and land use distort the environment leading to opportunities for the amplification of zoonoses. Implementing the OH approach at the national, local, and project level remains limited due to the lack of practical and tested operational methods for implementation and evaluation. In Kenya, the OH approach is spearheaded by the Zoonotic Disease Unit (ZDU). This study assessed the proportion of partners collaborating for OH, the methods, and the factors affecting multisectoral collaboration to confirm its effectiveness in controlling zoonoses in Kisumu County. Methods: A cross-sectional descriptive study design was used to generate information regarding the effectiveness of multisectoral collaboration in implementing the OH approach in the control of zoonoses. Descriptive statistics determined and assessed the nature, extent, and factors that affected multisectoral collaboration. Results: Multisectoral collaboration to control zoonoses in Kisumu was limited and driven mainly by public health officers (PHOs). Collaboration was enhanced through joint sensitizations and notifications whenever a zoonosis was suspected. The need for expertise outside one sector, the desire to promote OH, and the requirement to mainstream OH as a government policy prompted multisectoral collaboration. Conclusion: Multisectoral collaboration needed to be improved owing to a deficient OH policy hence the need for review to optimize the limited funding for training and infrastructure development, addressing staffing requirements, and setting up a robust information management system for data sharing.","PeriodicalId":211706,"journal":{"name":"One Health & Implementation Research","volume":"104 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128153815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eco-epidemiological studies to develop integrated vector surveillance of leishmaniasis vectors in the Americas","authors":"O. Salomón, M. G. Quintana","doi":"10.20517/ohir.2022.09","DOIUrl":"https://doi.org/10.20517/ohir.2022.09","url":null,"abstract":"We developed an integrated vector surveillance (IVS) proposal for cutaneous leishmaniasis (CL) and visceral leishmaniasis (VL) in the Americas, based on eco-epidemiological studies conducted by researchers of the Leishmaniasis Research Network of Argentina. For CL, the transmission was explained in the framework of the edge effect, the increase of vectors and risk of exposure at ecotones and environmental interfaces, and typified as ephemeral, transient, or permanent edges, supporting a cost-effective IVS strategy for early warning of CL outbreaks through an environmental modification alert network, which includes multiple sources of information and actors. In relation to VL, the earliest colonization sites and spatial distribution were explained by modeling and forecasting the most likely hotspots, persistent in time and space, and modulated by environmental variables. Therefore, for VL, a scalar strategy of critical site selection is proposed from a “city” scale based on secondary sources such as remote sensing for the definition of possible areas to monitor and intervene, a scale of restriction from possible to most likely areas through local knowledge, and a “focal site” scale of trap placement through field observation; in this way, IVS activities are carried out at a few sites of the urban landscape and allow a sustainable program.","PeriodicalId":211706,"journal":{"name":"One Health & Implementation Research","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121251505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current status of the treatment of paragonimiasis","authors":"J. Richter","doi":"10.20517/ohir.2022.10","DOIUrl":"https://doi.org/10.20517/ohir.2022.10","url":null,"abstract":"Paragonimiasis, a foodborne trematodiasis is caused by various Paragonimus species endemic in Asia, Africa, and the Americas. Human infection occurs through consuming improperly cooked freshwater crustaceans, crabs or crayfish, eating raw meat of paratenic hosts or by ingesting metacercariae from contaminated hands and cooking utensils. More than 292 million persons worldwide are at risk. The morbidity associated with paragonimiasis includes acute febrile illness and chronic pleuro-pulmonary manifestations which may be confounded with tuberculosis or lung cancer. Ectopic manifestations mostly involve the central nervous system, heart, or subcutaneous tissues. Objectives: to evaluate the efficacy and safety of currently available drugs praziquantel (PZQ) and triclabendazole (TCZ). Methods: a PubMed and Google Scholar search and reference selection was performed according to the the Preferred Reporting Items for Systematic Reviews protocol using a combination of the terms “paragonimiasis” AND “treatment” OR “therap*” from 01/2000 to 02/2022. Results: no randomized controlled trials were identified. Five open trials on 487 patients treated with PZQ showed 81%-100% parasite clearance depending on dosage and duration. Three open trials on 226 patients with TCZ showed a 99.6% efficacy. A quantitative comparison was not applicable to retrospective analyses of hospital records, case series and case reports because of surgical interventions, various co-morbidities and -medications and definitions of cure. Some patients treated with PZQ required multiple courses or re-treatment with TCZ, whereas one patient treated with TCZ required re-treatment with PZQ. Conclusions: PZQ and TCZ are usually effective for treating paragonimiasis. Controlled randomized trials are required to compare the safety, efficacy and applicability of PZQ versus TCZ and to evaluate combined PZQ-TCZ therapy.","PeriodicalId":211706,"journal":{"name":"One Health & Implementation Research","volume":"819 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133597424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of freshwater snail intermediate hosts of schistosomes in four communities from Osun State, Southwest Nigeria","authors":"U. Ugbomoiko, Issa I. Kareem, Doyinsola O. Awe, A. Babamale, Pam V. Gyang, T. Nwafor, O. Akinwale","doi":"10.20517/ohir.2022.05","DOIUrl":"https://doi.org/10.20517/ohir.2022.05","url":null,"abstract":"Aim: Freshwater snails of the genus Bulinus act as essential intermediate hosts of Schistosoma haematobium, a trematode parasite that causes urogenital schistosomiasis. The snails are widely distributed throughout Nigerian waters. Since species identification of the Bulinus snails is important for appropriate control strategies of urogenital schistosomiasis, this study therefore aimed at identifying the Bulinus species responsible for transmission of the infection in four communities located in an endemic Local Government Area of Nigeria. It also aimed at using restriction fragment length polymorphism (RFLP) as a more affordable method than sequencing to characterize Bulinus snails from schistosomiasis endemic regions in Nigeria. Methods: In this study, 100 freshwater snails morphologically identified as Bulinus species were collected from four communities located in a previously reported schistosomiasis endemic Local Government Area (LGA), namely Olorunda LGA in Oshun State, Southwest Nigeria. All snails were screened for schistosome infection using polymerase chain reaction (PCR) targeting the DraI gene. Molecular identification of the snails was done by PCR amplification of their entire internal transcribed spacer region including the 5.8S ribosomal RNA gene and RFLP. Results: Five of the 100 snails were positive for schistosome infection. PCR-RFLP profiles showed bands of different sizes for 26 other snails including the schistosome-infected ones. RFLP analysis showed that 11 of the snails belonged to the freshwater snails of the genus Physa while 13 belonged to the freshwater snails of the genus Bulinus, including Bulinus globosus (8) and B. truncatus (5). The species of the remaining two snails could not be resolved using the reference profiles from our previous studies. Conclusion: This study confirmed previous observations that limited morphological uniqueness within the Bulinus groups hinders their identification, and RFLP is a cheaper alternative method to sequencing that can be used by laboratories with limited resources for Bulinus species identification.","PeriodicalId":211706,"journal":{"name":"One Health & Implementation Research","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129409000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A qualitative exploration of perceptions of the COVID-19 vaccine in Malawi during the vaccine rollout phase","authors":"Elvis Safary, Caroline Mtaita","doi":"10.20517/ohir.2022.08","DOIUrl":"https://doi.org/10.20517/ohir.2022.08","url":null,"abstract":"Aim: Although the COVID-19 vaccine in Malawi has been well taken up and encouraged by the current administration, many individuals either are hesitant to get vaccinated for COVID-19 or refuse to do so. Research has uncovered associated demographic and psychological reasons, but there is a lack of qualitative work involving individuals across Malawi to explore reasons for this hesitancy. We aimed to explore factors leading to hesitation and/or refusal to COVID-19 vaccination in Malawi. Methods: The study utilized an online survey to collect free-text responses to assess factors leading to hesitation or refusal of COVID-19 vaccination in Malawi. The respondents were part of an ongoing community project in Central Malawi. In total, 284 individuals took part (72 males, 212 females). The mean age was 47.94 (SD = 8.36). Sixty-nine respondents (24.3%) had been vaccinated and 215 (75.7%) had not. An inductive thematic analysis was conducted. Results: Four themes were yielded, describing semi-colon fear of vaccination, becoming vaccinated to protect others, perceived pressure to be vaccinated, and perceptions of the COVID-19 vaccine being ineffective and experimental. Conclusion: Measures to increase COVID-19 vaccine uptake and acceptance should target fear and misinformation as constraints. Interventions such as individual sensitization and motivational interviewing should be considered for guiding individuals towards considering COVID-19 vaccination.","PeriodicalId":211706,"journal":{"name":"One Health & Implementation Research","volume":"411 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122782883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ecoepidemiology of dengue in Brazil: from the virus to the environment","authors":"Ana Beatriz Souza Martins, C. Alencar","doi":"10.20517/ohir.2021.10","DOIUrl":"https://doi.org/10.20517/ohir.2021.10","url":null,"abstract":"Dengue is an infectious disease caused by the dengue virus. In Brazil, the main vector is the mosquito Aedes aegypti (L.); however, Aedes albopictus (Skuse) can also transmit this pathogen. According to the WHO, more than 125 countries are endemic for dengue, and an estimated 50-100 million infections occur annually. In Brazil, the Northeast region is one with high incidence rates and records of successive epidemics. Dengue has been circulating in Brazil for over 30 years, due to the fact that there are areas that offer favorable environmental conditions, as well as municipalities with low socioeconomic conditions and frequent water crises. In addition, Brazil is a tourist hub with an intense flow of visitors, keeping the doors open for the entry and circulation of vector-borne diseases. The role of epidemiology is to analyze the distribution of diseases and their determinants in space and time and to unveil the social inequalities that influence the health-disease process. Thus, a review study that describes the occurrence of Dengue may provide a perspective of future areas of greater risk for dengue epidemics.","PeriodicalId":211706,"journal":{"name":"One Health & Implementation Research","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132598130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}