{"title":"Phytochemistry, Ethnobotanical uses and Pharmacology of Borago officinalis Linn: A Review","authors":"Archana Kumari, Kamal Jeet, Sanjay Kumar","doi":"10.52711/0975-4385.2023.00046","DOIUrl":"https://doi.org/10.52711/0975-4385.2023.00046","url":null,"abstract":"The plant Borage (Borago officinalis L.) family-Boraginaceae, also known as \"starflower\" is an annual herb originating in Syria, but naturalized throughout the Mediterranean region, as well as Asia Minor, Europe, North Africa, and South America. Aims of the Review The purpose of this study is to provide comprehensive scientific information on the phytochemistry, traditional uses and pharmacological activities of Borago officinalis L. The plant is reputed as hepatoprotective, gastrointestinal, respiratory anxiolytic, antispasmodic, antihypertensive, antipyretic, aphrodisiac, demulcent, diuretic and is also considered useful to treat asthma, bronchitis, cramps, palpitations and kidney ailments. Borage oil has been reported to lower serum cholesterol, phospholipids and triglyceride levels and increases the levels of 6 polyunsaturated fatty acids in the plasma, liver, aorta and renal artery tissues and ω -3 polyunsaturated fatty acids (PUFAs) obtained from Borago officinalis L. Dietary use of borage oil exhibited immuno -modulatory, cytotoxic and free radical scavenging activities. Borage has gained importance, due to the occurrence of high levels of g-linolenic acid in its seed oil. Flavonoids and phenolic compounds were the important essential oils in this plant and no have tannin. Borago officinalis extracts demonstrated excellent antioxidant properties and these effects were attributed to their phenolic constituents. Few studies examining Iron, Copper, Zinc and Manganese fertility in Borage have been conducted, but they are not specific to the medicinal use of this plant.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139281889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adesh S. Musale, Sakshi S. Bhandwakar, Dhananjay Ghodke, Devidas B. Nikam
{"title":"A Phytochemical Constituents and Pharmacological Properties of plant Tridax procumbeans","authors":"Adesh S. Musale, Sakshi S. Bhandwakar, Dhananjay Ghodke, Devidas B. Nikam","doi":"10.52711/0975-4385.2023.00045","DOIUrl":"https://doi.org/10.52711/0975-4385.2023.00045","url":null,"abstract":"Tridax procumbeans Linn., a member of the Asteraceae family, is an Ayurvedic herb that has been traditionally used in Asia. Throughout ancient times, Tridax procumbeans has been employed for the treatment of wounds, skin diseases, and as a remedy for preventing blood clotting in traditional medicine. It exhibits a range of beneficial properties including anticoagulant, antiseptic, insecticidal, antimicrobial, anticancer, and antioxidant effects. This herb is widely recognized for its therapeutic potential. Native to tropical America, Tridax procumbeans is found in tropical and subtropical regions worldwide, including various parts of India. Referred to as \"coat button\" in English and locally known as \"Ghamara,\" it is also commonly referred to as \"bhringraj\" and used in Ayurvedic medicine for liver diseases and hair problems. The plant's different components contain a variety of phytochemical compounds such as alkaloids, flavonoids, carotenoids, saponins, fumaric acid, and tannins. These compounds make it a valuable source for novel drug development. This review aims to provide a comprehensive understanding of the phytochemical constituents and pharmacological properties of T. procumbeans. Scientific research on Tridax procumbeans has been gathered from reputable sources such as ScienceDirect, Google Scholar, and PubMed.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"135 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139281854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Determination of Ash values of some Anti-anaemic Ethnomedicinal plants of Ranchi District, Jharkhand","authors":"Farha Fatma, Anil Kumar","doi":"10.52711/0975-4385.2023.00043","DOIUrl":"https://doi.org/10.52711/0975-4385.2023.00043","url":null,"abstract":"The traditional health care system (hodopathy) is based on the use of medicinal plants as the natural medications show better compatibility with human body, easily available with less side effects. These plants contain so many chemical compounds like alkaloids, flavonoids, tannins, saponins, phenolic compounds etc. that make them potential herbs and are used to cure various ailments like anaemia. Anaemia is a condition in which the hemoglobin level of the body decreases. The present study is based on extensive and intensive field survey that was made during 2019-2023. A large number of ethno medicinal plants have been documented during the survey work by interviewing local healers, knowledgeable persons, vaidyas etc. by preparing a questionnaire. Some of the medicinal plants like Psidium guajava, Carica papaya, Moringa oleifera and Spinacia oleracia were selected and ash values were determined which was found to be highest in Spinacea oleraceae i.e. 20.8 % followed by Moringa oleifera (14.5%), Carica papaya (14%) and Psidium guajava (9.5 %). The findings will help help in determining potential, quality and benefit of these plants in treatment of anaemia.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139281655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Overview of Trachyspermum ammi and its Medicinal applications","authors":"Nayan Rajaram Vharamble, Sanket Bhaskar Patil, Omkar Sanjay Naik, Rutuja Shah","doi":"10.52711/0975-4385.2023.00050","DOIUrl":"https://doi.org/10.52711/0975-4385.2023.00050","url":null,"abstract":"Trachyspermum ammi (1) Sprague or commonly Ajwain is a herbaceous herb belongs to the family Apiaceae and vastly grown in Egypt iran, Pakistan, Afghanistan, and India as well as European region. In India, it is mostly cultivated in Gujarat and Rajastan. Morphological features the fruit are consisting of two mericarps with bifid slyopod and have five light-coloured ridges. It is avoid in shape and has pungent taste, aromatic odour and is greyish brown in colour. It is 2mm long and 1mm wide in size. The temprature of fruit according to unani literature is hot and dry. The most useful element of ajwain is the little fruit like caraway, which always especially admired in Indian delectable recipes, flavorful baked goods, and snacks. In Ayurvedic meds, it is utilized as a restorative plant for its stimulant, carminative, antispasmodic, and tonic properties. The volatile components of essential oils mainly consist of monoterpenes, sesquiterpenes and their oxygenated derivatives such as alcohols, aldehyde, ketones, acids and esters (Suntar et al. 2014). Terpenes having a diverse variety of structures with specific functions constituted the largest amount (71.10%) of essential oils (Zule et al. 2003) Ajwain seeds revealed to possess antiseptic, stimulant, carminative, diuretic, anesthetic,antimicrobial, antiviral, nematicidal, antiulcer, antihypertensive, antitussive, bronchodilatory, antiplatelet and hepatoprotective as well as antihyperlipidemic effects, many of those were remarked by early Persian physicians.Ajwain methanolic extract revealed to exhibit in vivo hepatoprotective activity with 80% defense against an in general deadly dose of paracetamol in pests. The bronchodilatory impact of the decocted concentrate of Ajwain on the asthmatic patients' airways was inspected in an ensuing examination ponders. According to the outcomes, the concentrate has a reasonably bronchodilatory impact on asthmatic airways assessed to the impact of Theophylline at fixations utilized.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139282265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. N, Neha Basaiye, Roshan Lal Nanama, Sakhitha K.S., Sanjay Kumar, Anupam Srivastava
{"title":"Pharmaceutical and Preliminary Analytical Evaluation of Tutthamruta malahara","authors":"S. N, Neha Basaiye, Roshan Lal Nanama, Sakhitha K.S., Sanjay Kumar, Anupam Srivastava","doi":"10.52711/0975-4385.2023.00042","DOIUrl":"https://doi.org/10.52711/0975-4385.2023.00042","url":null,"abstract":"Malahara is an ointment an unique dosage form used for topical applications and have been introduced quite late as medicine in Ayurvedic System of Medicine. The current study aims to introduce Tutthamruta Malahara, as an easy preparation as explained in Rasatarangini a treatise of Ayurvedic Pharmaceutics (Ras Shastra avum Bhaishajya kalpna), with special indication in Paama Kushta. The formulation was prepared by adopting fusion method as per the classical reference. Analytical study was carried out to understand quality, purity of the formulation. Dark olive pastel green coloured, homogenous mixture with characteristic smell was obtained. Its refractive Index, spreadability, peroxide value acid values were 1.483, 11g.cm/ s, 41.01m eq O2/Kg, 0.35mg KOH/ g respectively and rancidity was absent. This study also evaluates the basic quality parameters of Malahara Kalpana.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139281789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Potential of Natural products for Chemoprevention of Breast Cancer","authors":"Ekta Khare, Aditi Sharma, Anurima Chowdhury, Shailendra Singh Narwariya","doi":"10.52711/0975-4385.2023.00048","DOIUrl":"https://doi.org/10.52711/0975-4385.2023.00048","url":null,"abstract":"Background: Breast cancer is the most frequent female cancer and one of the leading causes of cancer death in women. There are many chemotherapy agents available for the treatment of breast cancer. Still, the current therapeutic options have not fulfilled the desired outcomes, especially for drug-resistant breast cancer therapy. Thus, there is an urgent need to develop novel anti-breast cancer agents. Objective: This overview targets to portray the new advancement of herbal and artificial derivatives with anti-breast cancer potential, protecting the articles allotted from the ultimate year. Method: We found significant articles of interest in the field of breast cancer and proposed a review based on relevant information. Description of the studies included in the review. Result: Various key components are found in vegetables, fruits, seeds, nuts, coffee, tea, and wine. Therefore, dietary exposure is significant. Natural products having low-cost toxicity, their availability in foods, and their existence in a variety of herbal treatments, caution should be exercised in further assessment of their properties and applications. Conclusion: We tried to analyze the anti-breast cancer potency of quite a few extracts from different plant sources and to compare their antiproliferative efficiency of crude extracts with the action of their purified ingredients while an additional study is required.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139282106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nishigandha D. Naikawadi, Mayuri C. More, Prakash D. Jadhav, Sanket J. Kapse, V. Redasani
{"title":"A Review on Formulation Development using Chaulmoogra Oil","authors":"Nishigandha D. Naikawadi, Mayuri C. More, Prakash D. Jadhav, Sanket J. Kapse, V. Redasani","doi":"10.52711/0975-4385.2023.00049","DOIUrl":"https://doi.org/10.52711/0975-4385.2023.00049","url":null,"abstract":"To investigate the many bacteriocidal properties of chaulmoogra oil, which are used to treat leprosy and TB. Chaulmoogric acid, an antibacterial substance, is the main active component of chaulmoogra oil. The common name Chaulmoogra is used to refer to the tree Hydnocarpus kurzii, which belongs to the Flacourtiaceae family. Thailand, Myanmar, and India are the native countries of this tree. The two main Indian states where this tree can be found are Assam and Tripura. The ripe seeds of plants like Taraktogenos kurzii King, also called Hydnocarpus kurzii (King) Warb., Hydnocarpus wightiana Blume, Hydnocarpus anthelminticta Pierre, Hydnocarpus heterophylla, and other species of Hydnocarpus that are members of the Flacourtiaceae family are used to make the fixed oil known as chaulmoogra. Chaulmoogra oil has powerful bactericidal effect against the bacteria that cause leprosy and tuberculosis because it contains unsaturated fatty acids. Leprosy, TB, gout, and skin disorders have all been treated with it for millennia in Ayurveda.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139282306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Review Article on Phytochemical and Pharmacological Activities of Alpinia purpurata and Erythrina variegata","authors":"P. Sumi, N. N. Devi","doi":"10.52711/0975-4385.2023.00047","DOIUrl":"https://doi.org/10.52711/0975-4385.2023.00047","url":null,"abstract":"In this review the phytochemistry and pharmacology of an ornamental ginger, Alpinia purpurata (red ginger) and Erythrina variegata are updated. Alpinia is the largest genus in ginger family in which. The phytochemical studies on Alpinia purpurata revealed that it possess flavonoids, rutin, kaempferol-3-rutinoside and kaempferol-3-glucuronide. These phytoconstituents promote antimicrobial activity, anti-inflammatory disease and also have the potential to treat tuberculosis. It also serves as a potential source of natural antioxidants. Alpinia purpurata also used for headache, sore throat and renal disease. Plant Erythrina variegata rich in secondary metabolites such as phenolics, alkaloids, tannins. and saponins in their ethanolic extract. They also show anti-allergic, anti-inflammatory, antimicrobial and anticancer activity. In the phytochemical investigation, ethanolic extract of Erythrina variegata L. flowers confirmed more phytoconstituents while comparing to leaf and bark. The Erythrina variegata flowers exhibit more antioxidant activity and also have high protective activity against oxidative stress and also helps to fight against diseases like cancer, diabetes mellitus and other diseases.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139281819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kalyani U. Chande, Nikhil S. Ekhande, Mayuri H. Padwal
{"title":"Phytochemical and Pharmacological Activities of black Turmeric: A Review","authors":"Kalyani U. Chande, Nikhil S. Ekhande, Mayuri H. Padwal","doi":"10.52711/0975-4385.2023.00052","DOIUrl":"https://doi.org/10.52711/0975-4385.2023.00052","url":null,"abstract":"The plant Curcuma caesia, also referred to as kali haldi, is a member of the Zingiberaceae family. South East Asia's black turmeric is a rare endemic plant that also plays a significant role in traditional medicine. The north-east, central India, the Papi Hills of the East and West Godavari, and Andhra Pradesh all have access to this plant. The fresh and dried rhizomes of Curcuma cassia are used in traditional medicine to treat leucoderma, asthma, tumours, piles, bronchitis, bruising, and other conditions. Numerous therapeutic properties of curcuma caesia, including antioxidant, antibacterial, antipyretic, larvicidal, insecticidal, antimicrobial, wound healing, and anti-hyperglycemic, have been professionally investigated. The current study aims to provide a thorough overview of the literature on its phytochemistry, historical applications, and therapeutic research.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139281659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Synthesized green silver nano particles of Herpetospermum darjeelingense shows enhanced In vitro Antimicrobial, Antioxidant and Hepatoprotective activity","authors":"Sourav Chakraborty, S. Saha, M. Bhattacharya","doi":"10.52711/0975-4385.2023.00044","DOIUrl":"https://doi.org/10.52711/0975-4385.2023.00044","url":null,"abstract":"Silver nanoparticles (AgNP’s) are 1 - 100nm sized constituents providing additional surface area in formation of plentiful coordinate bonds with various ligands. Green mode of AgNP’s synthesis has aided in development of advanced formulations towards treating complex human ailments. Herpetospermum darjeelingense (C.B.Clarke) H. Schaef. and S.S. Renner is an under investigated endemic ethnomedicinally significant cucurbit climber with no work based on synthesis and exploration of biogenic AgNP’s being conducted previously employing its solvent extracts. This paper aims to provide insights on the green synthesized AgNP’s besides studying its antimicrobial, antioxidant and hepatoprotective efficacy. Methanolic extracts of H. darjeelingense were utilized to synthesize AgNP’s via reduction of silver nitrate following UV-Visible spectroscopic and scanning electron microscopic characterization depicting surface plasmon resonance bands at around 430nm wavelength with spherical to cubical shaped AgNP’s ranging between 40–80nm. The methanol based sample extracts did not portray any inhibition zone in antimicrobial assay with the AgNP’s showing considerable zone of inhibition against Escherichia coli, Klebsiella pneumoniae and Staphylococcus aureus indicating anti-microbial effectiveness of silver nano formulations. The highest free radical scavenging potential was shown by 50mg/ml (91.99%) silver nano formulation with minimal being recorded in 12.5mg/ml (50.11%) nanoparticle concentrate including a noted gradual increase in anti-lipid peroxidation ability from 12.5mg/ml (7.157±0.08273mg/ml Tocopherol equivalent) to 50mg/ml (18.128±0.03152mg/ml Tocopherol equivalent) nanoparticle formulation clearly portraying statistically significant elevated results in comparison to plain sample extracts depicting its anticipated usage in pharmaceutical applications concerning antibacterial, antioxidative and hepatoprotective features.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"124 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139282297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}