Reviews in cardiovascular medicine最新文献

{"title":"Gut Commensal <i>Bacteroides thetaiotaomicron</i> Promote Atherothrombosis via Regulating L-Tryptophan Metabolism.","authors":"Honghong Liu, Siqin Feng, Muyun Tang, Ran Tian, Shuyang Zhang","doi":"10.31083/j.rcm2511395","DOIUrl":"https://doi.org/10.31083/j.rcm2511395","url":null,"abstract":"<p><strong>Background: </strong>Coronary thrombosis events continue to be the leading cause of morbidity and mortality worldwide. Recently, emerging evidence has highlighted the role of gut microbiota in cardiovascular disease, but few studies have systematically investigated the gut microbiota variation associated with atherothrombosis.</p><p><strong>Methods: </strong>We conducted multi-omics analysis (metagenomics sequencing and serum metabolomics) on 146 subjects from Peking Union Medical College Hospital-Coronary Artery Disease (PUMCH-CAD) cohort. We analyzed the key strains and metabolic pathways related to coronary artery disease (CAD) development, explored the bacterial functional pathway which contributes to atherothrombosis at strain level in depth. Single strain colonization procedures on germ free mice demonstrated the promotion of platelet activation and thrombotic phenotypes of the disordered gut microbiota.</p><p><strong>Results: </strong>Gut microbiome and serum metabolome shifts were apparent in cases of CAD progression, <i>Bacteroides spp.</i> disturbed the development of CAD by participating in lipopolysaccharide (LPS), menaquinone and methanogenesis pathways. Particularly, coronary thrombosis is characterized by increased circulatory levels of L-tryptophan, which correlate with <i>Bacteroides thetaiotaomicron</i> that has enriched biosynthetic potential. In germ free mice we demonstrate that <i>Bacteroides thetaiotaomicron</i> colonization could induce thrombosis, aggravate platelet hyperreactivity and augment fecal levels of L-tryptophan.</p><p><strong>Conclusions: </strong>The disordered gut microbiota of CAD contributed to the occurrence and development of atherothrombosis. The key members of the bacterial and metabolic features may become biomarkers for predicting the cardiovascular thrombosis event. Targeting the microbial pathway may have the potential to reduce the incidence of cardiovascular disorders.</p><p><strong>Clinical trial registration: </strong>ChiCTR2000033897, https://www.chictr.org.cn/showproj.html?proj=55023.</p>","PeriodicalId":20989,"journal":{"name":"Reviews in cardiovascular medicine","volume":"25 11","pages":"395"},"PeriodicalIF":1.9,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11607515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142771788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipoprotein (a): Underrecognized Risk with a Promising Future.","authors":"Matteo Manzato, R Scott Wright, Allan S Jaffe, Vlad C Vasile","doi":"10.31083/j.rcm2511393","DOIUrl":"https://doi.org/10.31083/j.rcm2511393","url":null,"abstract":"<p><p>Lipoprotein a (Lp(a)) is a lipid biomarker that binds cholesterol and bears independent cardiovascular risk. Strategies to lower the level of Lp(a) and mitigate such risk are important both for primary and secondary prevention. Currently there are no approved therapies targeting Lp(a) directly. Lipid lowering therapies prescribed routinely may have no effect on Lp(a) levels. Some agents such as niacin and estrogens can significantly decrease Lp(a), but their use is not recommended due to their adverse safety profile. Statins increase Lp(a) levels by 10-20%, questioning the benefit of such therapy when this biomarker is elevated. The Food and Drug Administration (FDA) endorses new agents to address dyslipidemia such as proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9-i) and Inclisiran, a small interfering RNA. These approaches have been shown to also significantly reduce Lp(a), but more clinical data is needed before implementing their use in clinical practice. Clinical trials are currently ongoing to test the efficacy of newly developed antisense oligonucleotides and small interfering RNAs targeting the gene encoding for Lp(a) in hepatocytes, while other investigations assess small molecules that inhibit Lp(a) assembly. This review summarizes the pathophysiology and clinical implications of Lp(a) elevation, and focuses on proposed Lp(a) therapies and the current state of the clinical trials of such novel agents.</p>","PeriodicalId":20989,"journal":{"name":"Reviews in cardiovascular medicine","volume":"25 11","pages":"393"},"PeriodicalIF":1.9,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11607505/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142771791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Correlation between Preoperative Average Heart Rate and Postoperative Recurrence in Patients with Paroxysmal Atrial Fibrillation Undergoing Transcatheter Radiofrequency Ablation.","authors":"Xiu Feng, Ling Yang, Zhenni Yang, Yuxia Miao, Mingxia Gong, Jun Meng, Min Xu","doi":"10.31083/j.rcm2511394","DOIUrl":"https://doi.org/10.31083/j.rcm2511394","url":null,"abstract":"<p><strong>Background: </strong>Atrial fibrillation (AF) is the most common persistent arrhythmia, with increasing incidence worldwide. Transcatheter radiofrequency ablation (RFA) represents a first-line therapy for paroxysmal atrial fibrillation (PAF), although the long-term recurrence rate of AF remains relatively high. This study aimed to investigate the relationship between the average heart rate (AHR) on a dynamic electrocardiogram before transcatheter RFA and the postoperative recurrence of AF in patients with PAF.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on patients with PAF who experienced primary transcatheter RFA. Relevant clinical indicators, dynamic electrocardiograms, and echocardiography were collected from the enrolled patients before ablation. Multivariate logistic regression analysis examined the relationship between the preoperative AHR and postoperative recurrence of AF in patients with PAF.</p><p><strong>Results: </strong>This study included 224 patients with PAF who were scheduled for transcatheter RFA. Based on the AHR in sinus rhythm state on the dynamic electrocardiogram before ablation, the patients were divided into three groups: low, medium, and high heart rate. The recurrence rates of AF after ablation for the three groups were 14.667%, 8.108%, and 4.000%, respectively. After adjusting for confounding factors, postoperative AF recurrence risk gradually decreased with an increase in preoperative AHR (odds ratio: 0.849, 95% confidence interval: 0.729-0.988, <i>p</i> = 0.035). This trend remained statistically significant even after adjusting for the three categorical variables of AHR (odds ratio = 0.025, 95% confidence interval: 0.001-0.742, <i>p</i> = 0.033). The curve fitting analysis indicated a linear and negative correlation between the preoperative AHR and postoperative AF recurrence risk in patients with PAF.</p><p><strong>Conclusions: </strong>In patients with PAF who experienced their primary transcatheter RFA, there was a linear and negative correlation between the AHR in sinus rhythm state on the preoperative dynamic electrocardiogram and the risk of postoperative AF recurrence.</p>","PeriodicalId":20989,"journal":{"name":"Reviews in cardiovascular medicine","volume":"25 11","pages":"394"},"PeriodicalIF":1.9,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11607501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142771838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Sutureless Aortic Valve Replacement and Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-Analysis of Propensity Score Matching.","authors":"Shidong Liu, Hao Chen, Wenjun Zhou, Pengying Zhao, Liang Qi, Yalan Zhang, Bing Song, Cuntao Yu","doi":"10.31083/j.rcm2511391","DOIUrl":"https://doi.org/10.31083/j.rcm2511391","url":null,"abstract":"<p><strong>Background: </strong>To evaluate the clinical outcomes of sutureless aortic valve replacement (SUAVR) and transcatheter aortic valve implantation (TAVI).</p><p><strong>Methods: </strong>We systematically searched the electronic database and the Clinical Trials Registry up to 31 February 2023. Random effects model risk ratio (<i>RR</i>) and mean differences (MD) with corresponding 95% confidence intervals (CIs) were pooled for the clinical outcomes.</p><p><strong>Results: </strong>The included 16 studies using propensity-matched analysis consisted of 6516 patients, including 3258 patients in the SUAVR group and 3258 patients in the TAVI group. The SUAVR group had lower mortality than the TAVI group at 1-year [<i>RR</i> = 0.53, 95% CI (0.32, 0.87), <i>I</i> ² = 49%, <i>p</i> = 0.01], 2-year [<i>RR</i> = 0.56, 95% CI (0.37, 0.82), <i>I</i> ² = 51%, <i>p</i> = 0.03] and 5-year [<i>RR</i> = 0.56, 95% CI (0.46, 0.70), <i>I</i> ² = 0%, <i>p</i> < 0.01]. The SUAVR group had a significantly lower rate of new permanent pacemaker implantation (PPI) [<i>RR</i> = 0.74, 95% CI (0.55, 0.99), <i>I</i> ² = 48%, <i>p</i> = 0.04], moderate-to-severe paravalvular leak (PVL) [<i>RR</i> = 0.18, 95% CI (0.11, 0.30), <i>I</i> ² = 0%, <i>p</i> < 0.01], more-than-mild residual aortic regurgitation (AR) [<i>RR</i> = 0.27, 95% CI (0.14, 0.54), <i>I</i> ² = 0%, <i>p</i> < 0.01]. In addition, the SUAVR group had a higher rate of new-onset atrial fibrillation (AF) [<i>RR</i> = 3.66, 95% CI (1.95, 6.89), <i>I</i> ² = 84%, <i>p</i> < 0.01], major or life-threatening bleeding event [<i>RR</i> = 3.63, 95% CI (1.81, 7.28), <i>I</i> ² = 83%, <i>p</i> < 0.01], and higher postoperative mean aortic gradient [<i>MD</i> = 1.91, 95% CI (0.73, 3.10), <i>I</i> ² = 91%, <i>p</i> < 0.01] than the TAVI group.</p><p><strong>Conclusions: </strong>The early and mid-term clinical outcomes of SUAVR were superior compared to TAVI. Further studies should be conducted to highlight the specific subgroups of patients. that will benefit from each technique.</p><p><strong>Inplasy registration number: </strong>INPLASY 2022110058 (https://inplasy.com/inplasy-2022-11-0058/).</p>","PeriodicalId":20989,"journal":{"name":"Reviews in cardiovascular medicine","volume":"25 11","pages":"391"},"PeriodicalIF":1.9,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11607518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142771920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Exercise in Regulating the Generation of Extracellular Vesicles in Cardiovascular Diseases.","authors":"Peng Shen, Yue Qiu, Yan-Yan Sun, Yue-Ying Jiang, Xiu-Mei Guan, Min Cheng, Yan-Xia Wang","doi":"10.31083/j.rcm2511392","DOIUrl":"https://doi.org/10.31083/j.rcm2511392","url":null,"abstract":"<p><p>Extracellular vesicles (EVs) are nanoscale vesicles released by cells, which play an important role in intercellular communication by transporting proteins, lipids, nucleic acids, and other molecules. Different intensities of exercise can induce the release of EVs from cells and tissues, such as endothelial cells, skeletal muscle and adipose tissue, hepatocytes, immune cells, and neuronal cells. Exercise-induced EVs exert cardiovascular protective effects such as anti-inflammatory and anti-oxidative by altering their contents. This paper reviews the cell and tissue sources of EVs induced by exercise of different intensities, the regulatory effects of different exercise intensities on EVs, and their mechanisms of action in cardiovascular diseases. The aim is to provide new insights for the treatment of cardiovascular diseases and offer scientific evidence for the construction of engineered EVs mimicking the effects of exercise.</p>","PeriodicalId":20989,"journal":{"name":"Reviews in cardiovascular medicine","volume":"25 11","pages":"392"},"PeriodicalIF":1.9,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11607504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142771856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolic Consequences of Advanced Chronic Heart Failure and its Modification by Implantation of a Durable Left Ventricular Assist Device.","authors":"Daniel Hlaváček, Martin Haluzík, Jakub Mahrík, Ganna Popivnyak, Barbora J Kasperová, Peter Ivák","doi":"10.31083/j.rcm2511388","DOIUrl":"https://doi.org/10.31083/j.rcm2511388","url":null,"abstract":"<p><p>Heart failure (HF) is a clinical syndrome characterized by the inability of the heart to provide adequate perfusion to tissues and organs, resulting in typical symptoms such as fatigue, dyspnea, dyspepsia, or swelling due to decreased cardiac output. With its increasing prevalence, heart failure has become one of the leading causes of morbidity and mortality worldwide, imposing a significant burden on the population by reducing long-term life expectancy and raising hospital costs. Indeed, over 20 million people worldwide suffer from heart failure, with a 5-year mortality rate of 60-70%. As heart failure progresses, various structural and metabolic changes occur within the myocardium and organ systems. In the past two decades, therapeutic options for heart failure patients have significantly expanded. In addition to novel pharmacological treatment, advanced surgical methods such as heart transplantation (HTx) and the implantation of durable left ventricular assist devices (LVADs) are available for patients with end-stage heart failure. This review discusses the pathophysiological aspects and metabolic consequences of heart failure and metabolic changes, as well as the benefits and challenges of implanting a left ventricular assist device. Furthermore, future targets for heart failure diagnostics and therapy will be highlighted.</p>","PeriodicalId":20989,"journal":{"name":"Reviews in cardiovascular medicine","volume":"25 11","pages":"388"},"PeriodicalIF":1.9,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11607500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142771694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges and Innovations in Postoperative Care for Acute Type A Aortic Dissection: The Role of Structured Surveillance and Virtual Wards.","authors":"Robert Pruna-Guillen, Laerke Ghosh, Tara M Mastracci, Vikas Kapil, Ana Lopez-Marco, Aung Oo","doi":"10.31083/j.rcm2511389","DOIUrl":"https://doi.org/10.31083/j.rcm2511389","url":null,"abstract":"<p><p>Acute Type A aortic dissection (ATAAD) represents a life-threatening medical emergency that requires emergent surgical repair. Despite improvement in surgical techniques and perioperative management, ATAAD remains associated with high early mortality and postoperative complications. A structured and individualized postoperative surveillance program is essential, not only for improving survival rates but also for identifying risk factors necessitating reintervention and enhancing the quality of life. Comprehensive postoperative care should address both medical monitoring and psychological support to meet the holistic needs of ATAAD survivors. In real-world settings adherence to guideline-directed imaging surveillance (GDIS) is poor, leading to underestimation of reintervention rates. A comprehensive aortic service should include GDIS, clinical assessments, cardiovascular risk management, and psychological support. Since August 2022, a virtual ward has been implemented in our department to facilitate remote monitoring, ensuring tight blood pressure control and early detection of complications.</p>","PeriodicalId":20989,"journal":{"name":"Reviews in cardiovascular medicine","volume":"25 11","pages":"389"},"PeriodicalIF":1.9,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11607483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142771918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Salt Substitution on Cardiac Structure and ECG Parameters in Middle-aged and Elderly Hypertensive Patients.","authors":"Li Che, Ying Zhang, Xia Chen, Haiqing Du, Wei Song, Yinong Jiang","doi":"10.31083/j.rcm2511390","DOIUrl":"https://doi.org/10.31083/j.rcm2511390","url":null,"abstract":"<p><strong>Background: </strong>Salt substitution (SS) has been found to reduce blood pressure (BP). However, the impact of SS on cardiac structure, as assessed through ultrasonic cardiogram (UCG) and electrocardiograms (ECG), remains poorly understood. This study aims to evaluate the effects of SS on cardiac structure and ECG parameters.</p><p><strong>Methods: </strong>This 12-month prospective, multi-center, randomized, double-blind study involved hypertensive patients aged 50 to 70 years with office systolic BP (SBP) ranging from 140 to 180 mmHg and diastolic BP (DBP) ranging from 90 to 110 mmHg. A total of 352 patients were enrolled and equally randomized to either the normal salt (NS) group or SS group. Office BP measurements (OBPM) were obtained at baseline and at 3, 6, and 12 months, while home BP measurements (HBPM) were recorded at baseline, 3, 6, 9, and 12 months. Fasting blood, UCG, and ECG parameters were obtained at baseline and at the end of the study.</p><p><strong>Results: </strong>Of the 352 enrolled patients, 322 completed the study. In the SS group, the reductions in systolic OBPM, HBPM, and diastolic HBPM were significantly greater than those in the NS group. Notable cardiac parameter changes included a reduction in QT dispersion (QTd) by -5 ms (-10, 5) in the NS group and -5 ms (-15, 0) in the SS group (<i>p</i> = 0.001); the T wave peak-to-end (Tp-e) value was 0 ms (-5, 10) and -5 ms (-10, 0) (<i>p</i> < 0.001), respectively; and Tp-e/QT was 0 (-0.01, 0.02) and -0.02 (-0.04, 0) (<i>p</i> < 0.001), respectively. Additionally, left atrial diameter (LAD) was 0 mm (-1, 1) and -1 mm (-2, 1) (<i>p</i> < 0.001), and the change in left ventricular mass (LVM) was -2 g (-17.75, 11) and -7 g (-18, 6) (<i>p</i> = 0.035), respectively.</p><p><strong>Conclusions: </strong>This study demonstrates that SS not only significantly decreased LAD and LVM, indicating a significant effect on cardiac structure, but also improves UCG parameters, including reductions in QTd, Tp-e, and Tp-e/QT. These findings highlight the potential of SS as a beneficial intervention in managing cardiac risks in hypertensive patients.</p><p><strong>Clinical trial registration: </strong>ChiCTR1800019727. (https://www.chictr.org.cn/showproj.html?proj=31036).</p>","PeriodicalId":20989,"journal":{"name":"Reviews in cardiovascular medicine","volume":"25 11","pages":"390"},"PeriodicalIF":1.9,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11607495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142771757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on the Predictive Value of a Pulmonary Edema Imaging Score for Delayed Extubation in Patients after Heart Valve Surgery on Cardiopulmonary Bypass.","authors":"Xuefeng Lin, Funan Wang, Yuting Wang","doi":"10.31083/j.rcm2510387","DOIUrl":"10.31083/j.rcm2510387","url":null,"abstract":"<p><strong>Background: </strong>Delayed extubation with mechanical ventilation after cardiac valve surgery is an important clinical challenge. Early extubation can improve the survival rate and prognosis of patients. The study aims to explore the predictive value of a chest X-ray pulmonary edema imaging score on the first day after surgery for delayed extubation in patients after cardiac valve surgery on cardiopulmonary bypass.</p><p><strong>Method: </strong>Retrospective analysis of the clinical data of patients undergoing cardiac valve surgery under extracorporeal circulation admitted to the intensive care unit of Zhongshan Hospital Affiliated with Fudan University (Xiamen) from January 2020 to October 2023. The patients were divided into an early extubation group according to the postoperative mechanical ventilation time (time: <24 h) and a delayed extubation group (time: ≥24 h). The radiographic assessment of lung edema (RALE) score was performed on the chest X-ray of the patient on the first day after surgery to analyze the correlation between delayed extubation of mechanical ventilation and the chest radiograph RALE score on the first day after surgery and to verify its predictive performance.</p><p><strong>Results: </strong>Significant differences in age, the incidence of hypertension, body mass index (BMI), left ventricular ejection fraction (LVEF), pump time, RALE score, ventilation time, oxygenation index, P_aCO₂, and brain natriuretic peptide (BNP) levels after the first 24 h were seen between patients who were extubated before and 24 h post operation (<i>p</i> = 0.013, 0.001, 0.034, <0.001, <0.001, <0.001, <0.001, <0.001, 0.014, and <0.001, respectively). No significant differences were observed in the proportion of males and the lactate level after the first 24 h between the two groups (<i>p</i> = 0.792 and 0.191, respectively). The time of mechanical ventilation was positively correlated with the RALE score in all patients, and the correlation coefficient was 0.419; the difference was statistically significant (<i>p</i> < 0.001). Multivariate binary logistic regression analysis with stepwise regression was performed on each research factor, and it was found that RALE score, pump time, oxygenation index, and postoperative BNP were independent risk factors for predicting delayed extubation in patients undergoing cardiac surgery on cardiopulmonary bypass. A 10-fold cross-validation revealed that the mean accuracy, sensitivity, specificity, and area under the curve (AUC) of the regression model were 0.737, 0.749, 0.741, and 0.825, respectively.</p><p><strong>Conclusions: </strong>The RALE score on the chest radiograph on the first day after surgery is an independent risk factor for predicting delayed extubation in patients after cardiac valve surgery on cardiopulmonary bypass and has good predictive value.</p>","PeriodicalId":20989,"journal":{"name":"Reviews in cardiovascular medicine","volume":"25 10","pages":"387"},"PeriodicalIF":1.9,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11522776/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142558677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Advances in the Wearable Devices for Monitoring and Management of Heart Failure.","authors":"Victor Adeyi Odeh, Yifan Chen, Wenyan Wang, Xiaorong Ding","doi":"10.31083/j.rcm2510386","DOIUrl":"10.31083/j.rcm2510386","url":null,"abstract":"<p><p>Heart failure (HF) is an acute and degenerative condition with high morbidity and mortality rates. Early diagnosis and treatment of HF can significantly enhance patient outcomes through admission and readmission reduction and improve quality of life. Being a progressive condition, the continuous monitoring of vital signs and symptoms of HF patients to identify any deterioration and to customize treatment regimens can be beneficial to the management of this disease. Recent breakthroughs in wearable technology have revolutionized the landscape of HF management. Despite the potential benefits, the integration of wearable devices into HF management requires careful consideration of technical, clinical, and ethical challenges, such as performance, regulatory requirements and data privacy. This review summarizes the current evidence on the role of wearable devices in heart failure monitoring and management, and discusses the challenges and opportunities in the field.</p>","PeriodicalId":20989,"journal":{"name":"Reviews in cardiovascular medicine","volume":"25 10","pages":"386"},"PeriodicalIF":1.9,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11522764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142558674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}