Reviews in cardiovascular medicine最新文献

{"title":"New Insights into Cardiac Intensive Care.","authors":"Cheng Chen, Yanming Wu, Biao Wang","doi":"10.31083/RCM49773","DOIUrl":"10.31083/RCM49773","url":null,"abstract":"<p><p>In recent years, there have been significant advances in both theoretical knowledge and technological applications in cardiac intensive care, a crucial area of cardiovascular medicine. This study methodically outlines the most recent developments in the field's research, including new understandings of pathophysiological mechanisms, advancements in monitoring technology, improvements to prognostic evaluation systems, and optimization of therapeutic approaches. The article emphasizes cutting-edge advancements like artificial intelligence-assisted decision-making systems, microcirculation monitoring tools, and precision medicine approaches, which are customized to individual patient needs by combining evidence from basic research and clinical practice. Precision medicine in the cardiac intensive care unit (CICU) is described in this review as a reactive, patient-centered approach that uses real-time clinical, molecular, imaging, and hemodynamic data to customize acute therapeutic and monitoring interventions for critically ill cardiac patients with complicated, frequently multi-organ pathophysiology. Despite tremendous advancements, there are still difficulties in ensuring individualized care and converting these developments into standardized clinical procedures. In order to promote the development of standardized therapy and customized medical practice in this developing field, this thorough overview attempts to provide researchers and doctors with up-to-date information on cardiac intensive care.</p>","PeriodicalId":20989,"journal":{"name":"Reviews in cardiovascular medicine","volume":"27 7","pages":"49773"},"PeriodicalIF":2.2,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13419952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148631306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When Time Matters in Aortic Stenosis: Can Transcatheter Aortic Valve Replacement Make a Difference in Non-Elective Cases?","authors":"Cecilia Villa Etchegoyen, Laurève Chollet, Mina Ahmed, Christine Bilauca, Juan M Farina, Milagros Pereyra, Isabel G Scalia, Mahshad Razaghi, Fatmaelzahraa E Abdelfattah, Kamal Awad, Abdelrahman Hafez, Sherif Ahmed, Chadi Ayoub, Said Alsidawi, John P Sweeney, Steven J Lester, Kwan S Lee, David Fortuin, Kristen A Sell-Dottin, Reza Arsanjani","doi":"10.31083/RCM49738","DOIUrl":"10.31083/RCM49738","url":null,"abstract":"<p><strong>Background: </strong>The development of symptoms or left ventricular dysfunction in severe aortic stenosis (AS) is associated with high morbidity and mortality. While elective transcatheter aortic valve replacement (TAVR) is supported by robust randomized evidence, data on TAVR performed in non-elective settings (urgent, emergent, or salvage) remain limited and heterogeneous. In these settings, outcomes may be influenced more by baseline clinical severity than by procedural factors. This study aimed to systematically evaluate the safety and effectiveness of non-elective TAVR and to compare the associated outcomes with those of elective TAVR.</p><p><strong>Methods: </strong>This systematic review and meta-analysis were conducted in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines and registered with PROSPERO. The PubMed, Embase, and Scopus databases were searched for studies published after 2002 evaluating urgent, emergent, or salvage TAVR in adult patients with severe AS. Eligible studies were required to include elective TAVR as a comparator. Outcomes included mortality and major procedural complications. Prespecified era-based analyses and sensitivity analyses excluding studies at critical risk of bias were performed. Risk of bias was assessed using the ROBINS-I tool.</p><p><strong>Results: </strong>A total of 17 observational studies published between 2015 and 2025 were included, comprising 215,141 patients. Compared with elective patients, those undergoing non-elective TAVR had more advanced heart failure, higher NYHA class, greater comorbidity burden, and higher surgical risk scores, whereas baseline echocardiographic severity of AS was similar. Pooled outcomes for non-elective TAVR showed in-hospital, 30-day, and 1-year mortality rates of 5.1%, 12.4%, and 26.7%, respectively. Non-elective TAVR was associated with higher mortality at all time points compared with elective procedures; meanwhile, rates of stroke, vascular complications, and permanent pacemaker implantation were similar, while major bleeding and acute kidney injury were more frequent. Era-based analyses showed a stable relative mortality risk over time.</p><p><strong>Conclusions: </strong>Although non-elective TAVR is associated with worse outcomes than elective procedures, these differences appear to be largely driven by baseline clinical severity rather than by the transcatheter intervention. In unstable patients with severe AS, non-elective TAVR remains the most effective definitive treatment option compared with balloon aortic valvuloplasty or conservative management.</p><p><strong>The prospero registration: </strong>CRD420251239620, https://www.crd.york.ac.uk/PROSPERO/view/CRD420251239620.</p>","PeriodicalId":20989,"journal":{"name":"Reviews in cardiovascular medicine","volume":"27 7","pages":"49738"},"PeriodicalIF":2.2,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13419951/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148631348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echocardiography and Sports Cardiology: Expanding Horizons From Elite Athletes to Advanced Cardiovascular Disease.","authors":"Eduardo M Vilela, Francisco Sampaio, José Ribeiro, Ricardo Fontes-Carvalho","doi":"10.31083/RCM53090","DOIUrl":"10.31083/RCM53090","url":null,"abstract":"","PeriodicalId":20989,"journal":{"name":"Reviews in cardiovascular medicine","volume":"27 7","pages":"53090"},"PeriodicalIF":2.2,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13419963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148631165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Amr et al. Assessing the Applicability of Cardiac Myosin Inhibitors for Hypertrophic Cardiomyopathy Management in a Large Single Center Cohort. Reviews in Cardiovascular Medicine. 2024; 25(6): 225.","authors":"Ali Amr, Elham Kayvanpour, Christoph Reich, Jan Koelemen, Shamily Asokan, Norbert Frey, Benjamin Meder, Farbod Sedaghat-Hamedani","doi":"10.31083/RCM56238","DOIUrl":"10.31083/RCM56238","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.31083/j.rcm2506225.].</p>","PeriodicalId":20989,"journal":{"name":"Reviews in cardiovascular medicine","volume":"27 7","pages":"56238"},"PeriodicalIF":2.2,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13423721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148654316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary Exploration of Quantitative Stress Myocardial Contrast Echocardiography for Risk Stratification in Hypertrophic Cardiomyopathy: A 5-Year Prospective Study.","authors":"Ye Su, Chunmei Li, Lixue Yin","doi":"10.31083/RCM49216","DOIUrl":"10.31083/RCM49216","url":null,"abstract":"<p><strong>Background: </strong>Hypertrophic cardiomyopathy (HCM) is an autosomal dominant genetic cardiovascular disease caused by mutations in genes encoding sarcomeric proteins. Positron emission tomography (PET) has demonstrated prognostic value in assessing myocardial perfusion; however, the clinical utility of PET is limited by radiation exposure and cost. Myocardial contrast echocardiography (MCE) is a radiation-free, widely available imaging modality that shows promise for assessing microcirculatory function; however, the ability of MCE to predict long-term cardiovascular events in HCM remains unclear.</p><p><strong>Methods: </strong>This study recruited 142 patients with HCM and 80 healthy controls from the Sichuan Provincial People's Hospital. All participants underwent exercise-stress MCE to quantify myocardial perfusion using wash-in slope (WIS) and perfusion intensity (PI). Obstructive coronary artery disease was excluded by coronary computed tomography or invasive angiography. A 5-year follow-up was conducted for patients with HCM to monitor adverse cardiovascular events. Subgroup analyses were performed according to clinical event status, left ventricular outflow tract pressure gradient (LVOT-PG), and genetic classification.</p><p><strong>Results: </strong>The event-positive group showed significantly reduced resting and peak WIS and peak PI, along with complete loss of both WIS and PI reserves. Compared with the variant of uncertain significance (VUS) group, the genetic risk group had significantly lower resting and peak WIS and PI, with a significantly lower WIS reserve (ΔWIS) but comparable PI reserve (ΔPI). Among the resting obstruction, latent obstruction, and non-obstruction subgroups, WIS differed significantly, with the resting obstruction subgroup exhibiting the lowest WIS values and complete loss of both WIS and PI reserves. Resting and peak WIS were strongly and inversely correlated with adverse events. Receiver operating characteristic (ROC) analysis demonstrated that both resting and peak WIS had favorable predictive performance for adverse events.</p><p><strong>Conclusions: </strong>This preliminary, single-center, hypothesis-generating study suggests that WIS derived from exercise-stress MCE may be a useful marker for risk stratification in HCM; however, larger, multicenter studies are needed to confirm these findings.</p>","PeriodicalId":20989,"journal":{"name":"Reviews in cardiovascular medicine","volume":"27 7","pages":"49216"},"PeriodicalIF":2.2,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13419960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148631370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter Aortic Valve Replacement is Associated With a Lower Risk of Aortic Dissection Than Surgical Aortic Valve Replacement: A Propensity Score-Matched Analysis.","authors":"Mohamed Doma, Mangesh Kritya, Adham Ramadan, Ibrahim Kamel, Iuri Ferreira Felix, Seif Shlkamy, Shanmukh Sai Pavan Lingamsetty, Ahmed K Mahmoud, Mahmoud Ismayl, Ashwin Mahesh, Andrew M Goldsweig","doi":"10.31083/RCM50574","DOIUrl":"10.31083/RCM50574","url":null,"abstract":"<p><strong>Background: </strong>Aortic valve replacement is the primary treatment for aortic valve disease and can be performed using either transcatheter (TAVR) or surgical (SAVR) approaches. The risk of aortic dissection (AD) with TAVR compared with SAVR remains unclear. We aimed to compare AD risk between TAVR and SAVR using a large, real-world cohort.</p><p><strong>Methods: </strong>We conducted a retrospective cohort analysis using the TriNetX research network. Patients with a diagnosis of aortic stenosis, aortic insufficiency, mixed aortic valve disease (AVD), or unspecified AVDwho underwent either TAVR or SAVR were included. A 1:1 propensity score-matching (PSM) based on baseline characteristics was performed to adjust for potential confounding. Logistic regression and Cox proportional hazards models were used to estimate odds ratios (ORs) and hazard ratios (HRs), with 95% confidence intervals (CIs).</p><p><strong>Results: </strong>Among 95,043 patients undergoing isolated aortic valve replacement, 20,237 matched pairs were analyzed after 1:1 PSM. Baseline characteristics were well balanced, with a mean age of 73.3 ± 9.3 years in the TAVR group and 73.2 ± 8.5 years in the SAVR group; 60.8% and 60.7% were male, respectively. TAVR was associated with significantly lower odds of composite AD than SAVR at all time points (1-year OR 0.60; 95% CI 0.44-0.82; 3-year OR 0.64; 95% CI 0.48-0.83; 5-year OR 0.66; 95% CI 0.51-0.85; <i>p</i> < 0.01 for all). Stratified analyses demonstrated lower odds of both Stanford type A and type B AD at all time points. Kaplan-Meier analysis demonstrated a separation in composite AD-free survival between the two groups (HR 0.66; 95% CI 0.51-0.86; <i>p</i> = 0.002).</p><p><strong>Conclusion: </strong>In this large, real-world cohort, despite a low event rate, TAVR was associated with a significantly lower likelihood of composite AD than SAVR.</p>","PeriodicalId":20989,"journal":{"name":"Reviews in cardiovascular medicine","volume":"27 7","pages":"50574"},"PeriodicalIF":2.2,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13419957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148631290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Coronary Endarterectomy on Mid-Term Left Ventricular Functional Recovery in Diffuse Coronary Artery Disease.","authors":"Uğur Göçen, Mehmet Aslan, Murat Yüksel, Umut Serhat Sanrı, Dolunay Odabaşı, Onur Benli, Vecih Keklik","doi":"10.31083/RCM52886","DOIUrl":"10.31083/RCM52886","url":null,"abstract":"<p><strong>Purpose: </strong>Although coronary endarterectomy performed for diffuse coronary artery disease is known to increase early postoperative morbidity, its effects on mid-term myocardial functional recovery remain controversial. Therefore, this study aimed to examine changes in preoperative and sixth-month postoperative left ventricular ejection fraction, as assessed by echocardiography, in patients undergoing single or multiple coronary endarterectomy concomitantly with coronary artery bypass grafting.</p><p><strong>Methods: </strong>A total of 151 patients who underwent coronary artery bypass grafting with concomitant coronary endarterectomy, performed by experienced surgical teams between 2023 and 2025, were included in this retrospective, multicenter cohort study. Early morbidity and mortality were evaluated in the entire cohort of 151 patients, whereas the mid-term changes in echocardiographic left ventricular ejection fraction were examined in the remaining 138 patients after exclusion of the 13 patients who died in the early postoperative period. Recovery dynamics were analyzed according to the number of target vessels undergoing endarterectomy and aortic cross-clamp times.</p><p><strong>Results: </strong>Endarterectomy was performed on a total of 298 target lesions (mean 1.97 per patient) in the 151 patients included in the study, and multiple vessel endarterectomy was performed in 58.3% of the cases. The mean preoperative left ventricular ejection fraction was 46.6% ± 9.9%, and a clinically significant relative improvement of 16.8% was observed by the end of the sixth postoperative month (<i>p</i> < 0.001). Although multiple endarterectomy procedures and prolonged cross-clamp time tended to increase early morbidity, including postoperative atrial fibrillation and bleeding, no statistically significant difference was detected compared with single procedures (<i>p</i> > 0.05, <i>p</i> = 0.388)<i>.</i> In particular, complete revascularization of the left anterior descending artery territory was identified as the strongest predictor of functional recovery.</p><p><strong>Conclusions: </strong>Although coronary endarterectomy carries early risks related to increased surgical surface area and prolonged ischemia, it is associated with significant and sustained improvement in mid-term left ventricular functions among surviving patients, likely through reverse remodeling resulting from complete resolution of myocardial hibernation in the ischemic myocardium.</p>","PeriodicalId":20989,"journal":{"name":"Reviews in cardiovascular medicine","volume":"27 7","pages":"52886"},"PeriodicalIF":2.2,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13419988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148631224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammation-Mediated Mechanisms of Arrhythmias After Acute Myocardial Infarction.","authors":"Huijie Guo, Jin Liu, Jinchun Wu","doi":"10.31083/RCM49761","DOIUrl":"10.31083/RCM49761","url":null,"abstract":"<p><p>Acute myocardial infarction (AMI) remains a leading cause of cardiovascular death. Arrhythmias are the most common complication after AMI and can worsen disease progression and lead to sudden cardiac death (SCD). Therefore, prompt and accurate diagnosis, together with proactive and effective treatment, is crucial. This article reviews the mechanisms of inflammation in post-AMI arrhythmias, including inflammatory cell infiltration, cytokine release, oxidative stress, cardiac structural remodeling, and neuroimmune interactions. Additionally, this review discusses the predictive value of inflammatory markers and the clinical prospects of anti-inflammatory therapy, thereby providing a reference for future research and clinical prevention.</p>","PeriodicalId":20989,"journal":{"name":"Reviews in cardiovascular medicine","volume":"27 7","pages":"49761"},"PeriodicalIF":2.2,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13419948/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148631358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancements in Cardiac Magnetic Resonance Imaging: Innovations, Challenges, and Future Directions.","authors":"Jasmine K Dugal, Roger Woolley, Alexis Liszewski, Rooz Razmi, Sean Nemeh, Jaskirat S Malhi, Arpinder S Malhi, Aditi Singh","doi":"10.31083/RCM48251","DOIUrl":"10.31083/RCM48251","url":null,"abstract":"<p><p>Cardiac magnetic resonance (CMR) imaging has become one of the most comprehensive noninvasive tools for evaluating cardiac structure, function, and myocardial tissue characteristics. Moreover, the role of CMR imaging in cardiovascular tomography has become increasingly central, providing unparalleled insights across a wide range of cardiac diseases. Over the past decade, several technical advances have expanded the clinical applications of CMR imaging and strengthened the role of this modality in diagnosis and management. Therefore, this review synthesizes these rapid advances and the associated growing influence on contemporary cardiovascular imaging practice. This literature review examines recent advances in CMR imaging, including improved contrast agents, refined mapping techniques, integration of artificial intelligence (AI), and accelerated imaging protocols, and highlights how these innovations are enhancing CMR imaging performance and delivering meaningful benefits in clinical practice. Recent advances in CMR imaging include higher-resolution imaging, novel gadolinium-enhanced and parametric mapping sequences, strain imaging, and four-dimensional (4D) flow magnetic resonance imaging (MRI), enabling more comprehensive assessment of myocardial structure, function, and hemodynamics. Improvements in contrast agents, the development of gadolinium alternatives, and increasing integration of AI have further enhanced the diagnostic accuracy and workflow efficiency. Advances in CMR imaging have strengthened the role of this technique as a highly accurate and increasingly accessible tool for cardiovascular evaluation, despite ongoing challenges related to cost, patient tolerance, and contrast use. Future directions should include enhanced tissue characterization, integration with complementary imaging modalities, and continued technological innovation to expand clinical applications, improve patient outcomes, and reduce reliance on radiation-based techniques.</p>","PeriodicalId":20989,"journal":{"name":"Reviews in cardiovascular medicine","volume":"27 7","pages":"48251"},"PeriodicalIF":2.2,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13419998/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148631517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Undeflatable Coronary Balloons During Percutaneous Coronary Intervention: A Case-Based Review and Practical Bailout Algorithm.","authors":"Allam Harfoush, Tammam Harfouch, Muntasir Abo-Al-Hayja, Khaled Albouaini, Ammar Ezeldin, Hanady Hamdallah, Abdalazeem Ibrahem","doi":"10.31083/RCM51754","DOIUrl":"10.31083/RCM51754","url":null,"abstract":"<p><strong>Background: </strong>Undeflatable coronary balloons during percutaneous coronary intervention (PCI) are rare but particularly hazardous because persistent intracoronary inflation can cause abrupt coronary occlusion, ischaemia, and haemodynamic collapse. We aimed to synthesise the published experience to define mechanistic patterns, identify recurring predisposing factors, and propose a practical bailout algorithm.</p><p><strong>Methods and results: </strong>We performed a case-based review of PubMed, the Cochrane Library, and EBSCO from inception to February 2026. Eligible reports described balloons that could not be deflated while positioned in a coronary artery. A total of 15 coronary cases (2011-2025) met the inclusion criteria. Events occurred most often during post-dilatation or after stent deployment in complex anatomy, frequently involving severe calcification, aorto-ostial segments, chronic total occlusion-like lesions, and settings with limited guide engagement. Mechanistic patterns clustered into (i) intact-system non-deflation, where restoration of an exit pathway (system checks, sustained negative suction, and contrast dilution), followed by controlled decompression (wire puncture or mechanical- or energy-assisted disruption), was feasible; (ii) shaft-compromised events (fracture or detachment), where management shifted from decompression to mechanical retrieval, with surgery reserved for percutaneous failure.</p><p><strong>Conclusion: </strong>Undeflatable coronary balloons represent distinct failure modes with different viable rescue options. Outcomes appear to be driven by rapid restoration of perfusion and early recognition of shaft integrity. A structured escalation approach prioritising stabilisation, low-risk troubleshooting, controlled decompression, and decisive transition to retrieval, exclusion, or surgery when decompression is impossible could reduce secondary iatrogenic harm.</p>","PeriodicalId":20989,"journal":{"name":"Reviews in cardiovascular medicine","volume":"27 7","pages":"51754"},"PeriodicalIF":2.2,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13419944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148631374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}