{"title":"An Overview of Recent Patents and Patented Technology Platforms Based on Co-Processed Excipients.","authors":"Deepak Kaushik, Etisha Goel, Ravinder Verma, Parijat Pandey, Deepika Purohit, Vineet Mittal, Kuldeep Kumar, Md Habibur Rahman","doi":"10.2174/1872211314999210104211125","DOIUrl":"https://doi.org/10.2174/1872211314999210104211125","url":null,"abstract":"<p><strong>Background: </strong>There is no single-component excipient that fulfills all the requisite performance to allow an active pharmaceutical ingredient to be formulated into a specific dosage form. Co-processing is a novel concept that incorporates a combination of two or more excipients, that is advantageous and cannot be achieved using a physical admixture.</p><p><strong>Objective: </strong>This review provides an overview of co-processed excipients, recent patents granted and filed in this field and the commercial patented technology platforms based on these excipients.</p><p><strong>Methods: </strong>Various online patent databases were used for collecting the information on recent patents and patented co-processed excipient technologies. The recent patents such as single-step coprocessing by dry coating, novel co-processed excipients for oily drugs and novel silica-coated compositions have been discussed.</p><p><strong>Results: </strong>Co-processed excipients are evolving as a current and future trend of excipient technology in pharmaceutical manufacturing, which is evident by the increasing number of patents based on these excipients. Among various techniques, the maximum number of patents is based on the spray drying technique.</p><p><strong>Conclusion: </strong>In this work, the authors have focussed on recent patents and commercial technologies on co-processed excipient. A better understanding of this will help researchers and pharmaceutical industries to select the appropriate platform, or to develop new innovative co-processed excipients with improved tableting characteristics.</p>","PeriodicalId":20955,"journal":{"name":"Recent advances in drug delivery and formulation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38779701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preface.","authors":"Stefano Giovagnoli","doi":"10.2174/266738781501210816122827","DOIUrl":"https://doi.org/10.2174/266738781501210816122827","url":null,"abstract":"","PeriodicalId":20955,"journal":{"name":"Recent advances in drug delivery and formulation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39504716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nur Umairah Ali Hazis, Nagender Aneja, Rajan Rajabalaya, Sheba Rani David
{"title":"Systematic Patent Review of Nanoparticles in Drug Delivery and Cancer Therapy in the Last Decade.","authors":"Nur Umairah Ali Hazis, Nagender Aneja, Rajan Rajabalaya, Sheba Rani David","doi":"10.2174/1872211314666210521105534","DOIUrl":"https://doi.org/10.2174/1872211314666210521105534","url":null,"abstract":"<p><strong>Background: </strong>The application of nanotechnology has been considered a powerful platform in improving the current situation in drug delivery and cancer therapy, especially in targeting the desired site of action.</p><p><strong>Objective: </strong>The main objective of the patent review is to survey and review patents from the past ten years that are related to the two particular areas of nanomedicines.</p><p><strong>Methods: </strong>The patents related to the nanoparticle-based inventions utilized in drug delivery and cancer treatment from 2010 onwards were browsed in databases like USPTO, WIPO, Google Patents, and Free Patents Online. After conducting numerous screening processes, a total of 40 patents were included in the patent analysis. See the PRISMA checklist 2020 checklist.</p><p><strong>Results: </strong>Amongst the selected patents, an overview of various types of nanoparticles is presented in this paper, including polymeric, metallic, silica, lipid-based nanoparticles, quantum dots, carbon nanotubes, and albumin-based nanomedicines.</p><p><strong>Conclusion: </strong>Nanomedicines' advantages include improvements in terms of drug delivery, bioavailability, solubility, penetration, and stability of drugs. It is concluded that the utilization of nanoparticles in medicines is essential in the pursuit of better clinical practice.</p>","PeriodicalId":20955,"journal":{"name":"Recent advances in drug delivery and formulation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f6/e5/DDF-15-59.PMC8811617.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39504712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}