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Association of L432V (rs1056836) polymorphism of the CYP1B1 gene with the increased risk of colorectal cancer in the population of Central Russia CYP1B1基因L432V (rs1056836)多态性与俄罗斯中部人群结直肠癌风险增加的关系
RESEARCH RESULTS IN BIOMEDICINE Pub Date : 2022-09-20 DOI: 10.18413/2658-6533-2020-6-3-0-3
Alexander S. Moskalev
{"title":"Association of L432V (rs1056836) polymorphism of the CYP1B1 gene with the increased risk of colorectal cancer in the population of Central Russia","authors":"Alexander S. Moskalev","doi":"10.18413/2658-6533-2020-6-3-0-3","DOIUrl":"https://doi.org/10.18413/2658-6533-2020-6-3-0-3","url":null,"abstract":"","PeriodicalId":20921,"journal":{"name":"RESEARCH RESULTS IN BIOMEDICINE","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80367346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Aplastic anemia, clinical implications and DNA damage in workers with occupational exposure to aromatic hydrocarbons in Rio de Janeiro 里约热内卢职业接触芳香烃工人的再生障碍性贫血、临床意义和DNA损伤
RESEARCH RESULTS IN BIOMEDICINE Pub Date : 2022-09-20 DOI: 10.18413/2658-6533-2020-6-3-0-2
Karina Melo, F. Santiago, S. B. D. de Lucena, R. T. Silvestre, Maryah Bravo, U. Otero, Adenilson de Souza Fonseca, L. P. da Silva Sergio, L. Scherrer, Gilda Alves, M. H. Ornellas
{"title":"Aplastic anemia, clinical implications and DNA damage in workers with occupational exposure to aromatic hydrocarbons in Rio de Janeiro","authors":"Karina Melo, F. Santiago, S. B. D. de Lucena, R. T. Silvestre, Maryah Bravo, U. Otero, Adenilson de Souza Fonseca, L. P. da Silva Sergio, L. Scherrer, Gilda Alves, M. H. Ornellas","doi":"10.18413/2658-6533-2020-6-3-0-2","DOIUrl":"https://doi.org/10.18413/2658-6533-2020-6-3-0-2","url":null,"abstract":"","PeriodicalId":20921,"journal":{"name":"RESEARCH RESULTS IN BIOMEDICINE","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84890716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Investigation of cerebroprotective properties of the drug «Mexidol» on the model of pneumococcal bacterial meningitis in experimental conditions 药物“墨西多”对实验性肺炎球菌细菌性脑膜炎模型脑保护特性的研究
RESEARCH RESULTS IN BIOMEDICINE Pub Date : 2022-09-20 DOI: 10.18413/2658-6533-2020-6-3-0-8
S. Skachilova, A. Agarkova
{"title":"Investigation of cerebroprotective properties of the drug «Mexidol» on the model of pneumococcal bacterial meningitis in experimental conditions","authors":"S. Skachilova, A. Agarkova","doi":"10.18413/2658-6533-2020-6-3-0-8","DOIUrl":"https://doi.org/10.18413/2658-6533-2020-6-3-0-8","url":null,"abstract":"","PeriodicalId":20921,"journal":{"name":"RESEARCH RESULTS IN BIOMEDICINE","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77629882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Features of myocardial infarction with ST segment elevation in patients of the older age group 老年组ST段抬高型心肌梗死的特点
RESEARCH RESULTS IN BIOMEDICINE Pub Date : 2022-09-20 DOI: 10.18413/2658-6533-2020-6-3-0-10
O. Osipova, Vladislav V. Bukatov
{"title":"Features of myocardial infarction with ST segment elevation in patients of the older age group","authors":"O. Osipova, Vladislav V. Bukatov","doi":"10.18413/2658-6533-2020-6-3-0-10","DOIUrl":"https://doi.org/10.18413/2658-6533-2020-6-3-0-10","url":null,"abstract":"","PeriodicalId":20921,"journal":{"name":"RESEARCH RESULTS IN BIOMEDICINE","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88124408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The proresilients in multimodal programmes for the prevention of premature ageing 预防早衰的多模式方案的促进因素
RESEARCH RESULTS IN BIOMEDICINE Pub Date : 2022-09-20 DOI: 10.18413/2658-6533-2020-6-3-0-9
Vitautas Rubikas, Tatsiana Piatryshcha, O. Rozhdestvenskaya, Elena Voronina, Alena Gerois
{"title":"The proresilients in multimodal programmes for the prevention of premature ageing","authors":"Vitautas Rubikas, Tatsiana Piatryshcha, O. Rozhdestvenskaya, Elena Voronina, Alena Gerois","doi":"10.18413/2658-6533-2020-6-3-0-9","DOIUrl":"https://doi.org/10.18413/2658-6533-2020-6-3-0-9","url":null,"abstract":"Background: Premature ageing is a common process. According to various authors, at least 10-20% of middle-aged people have unfavorable levels of discrepancy be-tween biological and passport age. That is why the preventive direction is actively developing in gerontology. Various substances like the proresilients, for example, are actively studied for their geroprotective properties in terms of their impact on cellular mechanisms of premature ageing. The aim of the study: To study the properties of the proresilients in multimodal programs for the prevention of premature ageing. Materials and methods: We studied literary figures for 2015-2020 in computer databases, PubMed, Medical-Science, Elibrary, Ceeol, JSTOR, Web of Science, Sco-pus. Results: The proresilients are used in various programs for improving the body and reducing the aging process of cells, reducing oxidative stress and other pathological mechanisms. They act at the level of the cell so they can slow down the destruction of organs and balance systems. This is due to their positive effect on the entire body and the patient's well-being. The proresilients have the criteria of a good pharmaceutical practices and quality criteria of 4G. The application of the proresilients is important in three areas of medicine like cosmetology, anti-ageing and preventive medicine. Age-related skin changes are inevitable, but it is important to take measures to prevent premature ageing. That‘s why it`s important to use the proresili-ents to prevent skin changes and premature ageing. Conclusion: In conclusion, the proresilients is a new, actively developed group of nutraceutical drugs that can be successfully used in modern health management technologies in multi-modal prevention and rehabilitation programs","PeriodicalId":20921,"journal":{"name":"RESEARCH RESULTS IN BIOMEDICINE","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91525047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modern genomics in studying the problems of human adaptation to climate in north Siberia 现代基因组学在研究西伯利亚北部人类气候适应问题中的应用
RESEARCH RESULTS IN BIOMEDICINE Pub Date : 2022-09-20 DOI: 10.18413/2658-6533-2020-6-3-0-4
L. Osipova, D. Lichman, B. Hallmark, T. Karafet, Ping Hsun Hsieh, Joseph Watkins, M. F. Hammer
{"title":"Modern genomics in studying the problems of human adaptation to climate in north Siberia","authors":"L. Osipova, D. Lichman, B. Hallmark, T. Karafet, Ping Hsun Hsieh, Joseph Watkins, M. F. Hammer","doi":"10.18413/2658-6533-2020-6-3-0-4","DOIUrl":"https://doi.org/10.18413/2658-6533-2020-6-3-0-4","url":null,"abstract":"","PeriodicalId":20921,"journal":{"name":"RESEARCH RESULTS IN BIOMEDICINE","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84879503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The final results of the ASSA-II study: the knowledge of therapeutic doctors on the subject of bronchial asthma asa - ii研究的最终结果:治疗性医生对支气管哮喘的认识
RESEARCH RESULTS IN BIOMEDICINE Pub Date : 2022-09-20 DOI: 10.18413/2658-6533-2020-6-3-0-7
R. Bontsevich, Olga I. Zemlyanskaya, A. Mikhno, G. Prozorova, E. Ebzeeva, I. F. Krotkova, O. Kompaniets, Elena V. Myronenko, E. Luchinina, G. Ketova, V. Barysheva, I. Galkina, M. L. Maximov
{"title":"The final results of the ASSA-II study: the knowledge of therapeutic doctors on the subject of bronchial asthma","authors":"R. Bontsevich, Olga I. Zemlyanskaya, A. Mikhno, G. Prozorova, E. Ebzeeva, I. F. Krotkova, O. Kompaniets, Elena V. Myronenko, E. Luchinina, G. Ketova, V. Barysheva, I. Galkina, M. L. Maximov","doi":"10.18413/2658-6533-2020-6-3-0-7","DOIUrl":"https://doi.org/10.18413/2658-6533-2020-6-3-0-7","url":null,"abstract":"","PeriodicalId":20921,"journal":{"name":"RESEARCH RESULTS IN BIOMEDICINE","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91391364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polymorphism of the VEGFA gene, smoking and coronary heart disease: the significance of gene-environmental interactions for disease susceptibility VEGFA基因多态性、吸烟与冠心病:基因-环境相互作用对疾病易感性的意义
RESEARCH RESULTS IN BIOMEDICINE Pub Date : 2022-09-20 DOI: 10.18413/2658-6533-2020-6-3-0-6
M. Solodilova, M. Medvedeva, M. Bykanova, O. Vasilyeva, V. Ivanov
{"title":"Polymorphism of the VEGFA gene, smoking and coronary heart disease: the significance of gene-environmental interactions for disease susceptibility","authors":"M. Solodilova, M. Medvedeva, M. Bykanova, O. Vasilyeva, V. Ivanov","doi":"10.18413/2658-6533-2020-6-3-0-6","DOIUrl":"https://doi.org/10.18413/2658-6533-2020-6-3-0-6","url":null,"abstract":"","PeriodicalId":20921,"journal":{"name":"RESEARCH RESULTS IN BIOMEDICINE","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83553530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2q14 de novo interstitial deletion in a girl with intellectual disabilities and malformations 智力残疾和畸形女童的2q14间质缺失
RESEARCH RESULTS IN BIOMEDICINE Pub Date : 2022-09-20 DOI: 10.18413/2658-6533-2020-6-3-0-1
Yomisisleidy B. Alvarez, A. García, L. M. Rosales, L. Méndez-Rosado
{"title":"2q14 de novo interstitial deletion in a girl with intellectual disabilities and malformations","authors":"Yomisisleidy B. Alvarez, A. García, L. M. Rosales, L. Méndez-Rosado","doi":"10.18413/2658-6533-2020-6-3-0-1","DOIUrl":"https://doi.org/10.18413/2658-6533-2020-6-3-0-1","url":null,"abstract":"Background: Neurodevelopmental disorders have a prevalence of approximately 3% in the population, the genetic factor is involved in this condition. Microdeletions that comprise the 2q14.1q14.3 region are rare events. The aim of the study: To describe a girl with an interstitial deletion of the 2q14 region with a severely affected phenotype and to compare her with reports from the international literature. Materials and methods: Cell culture and the obtaining of chromosomes were carried out according to the standardized techniques in our laboratory. Results: Girl evaluated for dismorphias and brain malformation (corpus callosum agenesis). The chromosomal study with a resolution of 565 bands showed an interstitial deletion in the long arm of chromosome 2. Karyotype: 46, XX, del (2) (q14.1q14.2). Conclusion: The correct clinical analysis of the patient and the high-resolution cytogenetic technique has been successful for detection of the microdeletion in this case helping in genetic counseling and in elucidating the genetic origin of the patient's neurodevelopmental disorder.","PeriodicalId":20921,"journal":{"name":"RESEARCH RESULTS IN BIOMEDICINE","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74029093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Premature birth modern realities 早产的现代现实
RESEARCH RESULTS IN BIOMEDICINE Pub Date : 2022-09-20 DOI: 10.18413/2658-6533-2020-6-3-0-12
Anna S. Fomina
{"title":"Premature birth modern realities","authors":"Anna S. Fomina","doi":"10.18413/2658-6533-2020-6-3-0-12","DOIUrl":"https://doi.org/10.18413/2658-6533-2020-6-3-0-12","url":null,"abstract":"","PeriodicalId":20921,"journal":{"name":"RESEARCH RESULTS IN BIOMEDICINE","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76240661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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