Reproductive Health最新文献

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Opportunities for improving abortion care: a key stakeholder analysis of best practices for addressing the needs of transgender, nonbinary, and gender expansive people seeking abortions. 改善堕胎护理的机会:主要利益相关者对满足寻求堕胎的变性人、非二元人和性别扩张者需求的最佳做法的分析。
IF 3.6 2区 医学
Reproductive Health Pub Date : 2024-09-27 DOI: 10.1186/s12978-024-01863-5
Aliza J Barnett, Subasri Narasimhan, Sophie A Hartwig, Anna Newton-Levinson
{"title":"Opportunities for improving abortion care: a key stakeholder analysis of best practices for addressing the needs of transgender, nonbinary, and gender expansive people seeking abortions.","authors":"Aliza J Barnett, Subasri Narasimhan, Sophie A Hartwig, Anna Newton-Levinson","doi":"10.1186/s12978-024-01863-5","DOIUrl":"10.1186/s12978-024-01863-5","url":null,"abstract":"<p><strong>Objectives: </strong>Transgender, nonbinary, and gender expansive (TGE) persons experience pregnancies and have abortions, yet abortion care remains rooted in a gender binary, often centering the needs, experiences, and challenges of cisgender women. Despite guidance supporting gender-affirming sexual and reproductive healthcare (SRH), barriers for TGE people seeking abortions persist. We conducted an exploratory case study with key informants to understand their perception of TGE abortion seekers' needs with specific considerations for those in restrictive abortion settings.</p><p><strong>Methods: </strong>Qualitative interviews focused on gender-affirming care and abortion provision were conducted with U.S.-based key informant clinicians (n = 4) who could provide powerful insights into gaps and experiences faced by TGE individuals. Participants were eligible if they currently or previously provided abortions and had experience practicing gender-affirming care. Interviews focused on informants' perceptions of TGE patients' needs when seeking abortions.</p><p><strong>Results: </strong>Findings highlight the unique barriers TGE patients face when seeking abortions, including lack of provider knowledge, in-clinic stigmatization, and gender marginalization. It is notable that key informants who practiced in abortion-protective political environments have greater access to resources to implement gender-affirming care than those in restrictive contexts. Results are summarized in a clinical recommendations document which provides an accessible starting point for clinicians to begin building gender-inclusive abortion spaces.</p><p><strong>Conclusions: </strong>It is necessary to further understand barriers facing TGE abortion seekers and integrate recommendations and emerging evidence into abortion practice. This study contributes to a growing knowledge base which emphasizes the need for inclusive abortion spaces and highlights key considerations for improving access and quality for TGE abortions seekers.</p>","PeriodicalId":20899,"journal":{"name":"Reproductive Health","volume":"21 1","pages":"137"},"PeriodicalIF":3.6,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11437809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142352748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Telemedicine for the provision of medication abortion to pregnant people at up to twelve weeks of pregnancy: a systematic literature review and meta-analysis 为怀孕 12 周以内的孕妇提供药物流产的远程医疗:系统文献综述和荟萃分析
IF 3.4 2区 医学
Reproductive Health Pub Date : 2024-09-19 DOI: 10.1186/s12978-024-01864-4
Leonardo Cely-Andrade, Karen Cárdenas-Garzón, Luis Carlos Enríquez-Santander, Biani Saavedra-Avendano, Guillermo Antonio Ortiz Avendaño
{"title":"Telemedicine for the provision of medication abortion to pregnant people at up to twelve weeks of pregnancy: a systematic literature review and meta-analysis","authors":"Leonardo Cely-Andrade, Karen Cárdenas-Garzón, Luis Carlos Enríquez-Santander, Biani Saavedra-Avendano, Guillermo Antonio Ortiz Avendaño","doi":"10.1186/s12978-024-01864-4","DOIUrl":"https://doi.org/10.1186/s12978-024-01864-4","url":null,"abstract":"Telemedicine represents an important strategy to facilitate access to medication abortion (MAB) procedures, reduces distance barriers and expands coverage to underserved communities. The aim is evaluating the self-managed MAB (provided through telemedicine as the sole intervention or in comparison to in-person care) in pregnant people at up to 12 weeks of pregnancy. A literature search was conducted using electronic databases: MEDLINE, Embase, Cochrane (Central Register of Controlled Trials and Database of Systematic Reviews), LILACS, SciELO, and Google Scholar. The search was based on the Population, Intervention, Comparison, Outcome, and Study Design (PICOS) framework, and was not restricted to any years of publication, and studies could be published in English or Spanish. Study screening and selection, risk of bias assessment, and data extraction were performed by peer reviewers. Risk of bias was evaluated with RoB 2.0 and ROBIS-I. A narrative and descriptive synthesis of the results was conducted. Meta-analyses with random-effects models were performed using Review Manager version 5.4 to calculate pooled risk differences, along with their individual 95% confidence intervals. The rate of evidence certainty was based on GRADE recommendations. 21 articles published between 2011 and 2022 met the inclusion criteria. Among them, 20 were observational studies, and 1 was a randomized clinical trial. Regarding the risk of bias, 5 studies had a serious risk, 15 had a moderate risk, and 1 had an undetermined risk. In terms of the type of intervention, 7 compared telemedicine to standard care. The meta-analysis of effectiveness revealed no statistically significant differences between the two modalities of care (RD = 0.01; 95%CI 0.00, 0.02). Our meta-analyses show that there were no significant differences in the occurrence of adverse events or in patient satisfaction when comparing the two methods of healthcare delivery. Telemedicine is an effective and viable alternative for MAB, similar to standard care. The occurrence of complications was low in both forms of healthcare delivery. Telemedicine services are an opportunity to expand access to safe abortion services. Globally, unsafe abortion causes 47,000 deaths and 5 million sexual and reproductive dysfunctions in young pregnant people due to complications of the procedure. This practice is related to barriers to accessing safe abortion services secondary to health system limitations and inequities in the distribution of resources. Telemedicine has proven to be an efficient care alternative to reduce distancing gaps, decrease waiting time and rationalize the costs derived from the procedure. Consequently, several health systems in the world use this model with differences in treatment schemes, weeks of gestation, pregnancy confirmation methods and measurement of reported outcomes. For this reason, evaluating the effectiveness and safety of self-managed medication abortion (MAB) by telemedicine is a sup","PeriodicalId":20899,"journal":{"name":"Reproductive Health","volume":"65 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142252991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Socioecologies in shaping migrants and refugee youths’ sexual and reproductive health and rights: a participatory action research study 影响移民和难民青年性健康和生殖健康及权利的社会生态:参与式行动研究
IF 3.4 2区 医学
Reproductive Health Pub Date : 2024-09-18 DOI: 10.1186/s12978-024-01879-x
Michaels Aibangbee, Sowbhagya Micheal, Pranee Liamputtong, Rashmi Pithavadian, Syeda Zakia Hossain, Elias Mpofu, Tinashe Dune
{"title":"Socioecologies in shaping migrants and refugee youths’ sexual and reproductive health and rights: a participatory action research study","authors":"Michaels Aibangbee, Sowbhagya Micheal, Pranee Liamputtong, Rashmi Pithavadian, Syeda Zakia Hossain, Elias Mpofu, Tinashe Dune","doi":"10.1186/s12978-024-01879-x","DOIUrl":"https://doi.org/10.1186/s12978-024-01879-x","url":null,"abstract":"This study explores socioecological factors facilitating the sexual and reproductive health and rights (SRHR) experiences of migrant and refugee youth (MRY) in Greater Western Sydney, Australia. MRY may be at higher risk for poorer SRH outcomes due to cultural, linguistic, and systemic barriers. Using participatory action research, 17 focus groups were conducted with 87 MRY aged 15–29 from diverse cultural backgrounds. Data were analysed thematically, using socioecological framework. Key facilitators of MRY's SRHR were identified at the microsystem and exosystem levels, including (1) Peer dynamics and support, with friends serving as trusted confidants and sources of advice; (2) Safety and contraceptive choices, highlighting the importance of access to contraception and STI prevention; and (3) Digital platforms for SRHR information access, with online resources filling knowledge gaps. Findings suggest the need for SRHR interventions to leverage peer support networks, expand access to contraceptive options, and develop culturally appropriate digital resources for MRY. Further research is needed to identify and enhance facilitators across all socioecological levels to comprehensively support MRY's SRHR needs. Migrants and refugee youth often struggle to access sexual and reproductive health information and services in their new countries. This study is an attempt to understand what helps young migrants and refugee maintain their sexual and reproductive health and rights in Greater Western Sydney, Australia. Our aim was to identify the positive factors in their environment that make it easier for them to access and use sexual health resources. We talked to 87 migrants and refugee youth aged 15–29 from various cultural backgrounds, conducting 17 group discussions about their experiences with sexual health. Our main results show three important factors that help these young people. The results were, that (1) Many young people trust their friends for advice and information about sexual health, (2) Having choices about contraception and ways to prevent sexually transmitted infections was important, and (3) The internet, especially social media and search engines, is a major source of sexual health information for young people. Understanding these helpful factors can guide better support for young migrants and refugees. It shows sexual health programs need to use peer support in sexual health programs, make sure young people can easily access contraception and protection and create trustworthy online resources about sexual health that are culturally appropriate. Our findings show more research is needed to find other ways to support young migrants and refugees with their sexual and reproductive health. This will help create better health services and education programs for these young people.","PeriodicalId":20899,"journal":{"name":"Reproductive Health","volume":"7 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142252958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of perceived stress on fertility intention among women of childbearing age without children: multiple mediating effect of anxiety, family communication and subjective well-being 无子女育龄妇女感知到的压力对生育意愿的影响:焦虑、家庭沟通和主观幸福感的多重中介效应
IF 3.4 2区 医学
Reproductive Health Pub Date : 2024-09-18 DOI: 10.1186/s12978-024-01855-5
Jinping Zhao, Weijing Qi, Yu Cheng, Ran Hao, Meina Yuan, Haoyu Jin, Yongjian Wang, Huicong Lv, Yibo Wu, Jie Hu
{"title":"Influence of perceived stress on fertility intention among women of childbearing age without children: multiple mediating effect of anxiety, family communication and subjective well-being","authors":"Jinping Zhao, Weijing Qi, Yu Cheng, Ran Hao, Meina Yuan, Haoyu Jin, Yongjian Wang, Huicong Lv, Yibo Wu, Jie Hu","doi":"10.1186/s12978-024-01855-5","DOIUrl":"https://doi.org/10.1186/s12978-024-01855-5","url":null,"abstract":"In recent years, there has been a significant decrease in the desire to have children among Chinese women of childbearing age, particularly for the first child. This trend has sparked a growing interest in understanding the underlying factors. Although perceived stress has been speculated as an important factor in decreasing fertility intention, the precise mechanism is unclear. The current study, therefore, aims to investigate the psychological mechanisms linking perceived stress to fertility intentions among women of childbearing age without children, a topic of significant relevance and importance. Data were sourced from Chinese residents' psychology and behavior investigation (PBICR-2022). A multistage random sampling method was applied to recruit eligible participants. The Mplus8.3 software constructed a chain path model among the variables. The median fertility intention was 30(3–60) on a scale of 0 to 100. The mediation analysis revealed a significant negative influence of perceived stress on fertility intention (β = − 0.076, P < 0.001). Additionally, a more intricate pattern of chain-mediating effect was observed involving perceived stress, anxiety (β = 0.037, P < 0.05), family communication (β = 0.106, P < 0.001), subjective well-being (β = 0.088, P < 0.001) and fertility intention. Perceived stress not only directly suppressed fertility intention but also indirectly affected it through anxiety, family communication, and subjective well-being. Effective family communication and favorable subjective well-being emerged as factors that could augment fertility intentions among women of childbearing age without children.","PeriodicalId":20899,"journal":{"name":"Reproductive Health","volume":"44 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142252956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contraceptive risk events among family planning specialists: a cross sectional study 计划生育专家的避孕风险事件:一项横断面研究
IF 3.4 2区 医学
Reproductive Health Pub Date : 2024-09-13 DOI: 10.1186/s12978-024-01870-6
Taylor N. Weckstein, Rebecca G. Simmons, Jami Baayd, Kathryn E. Fay
{"title":"Contraceptive risk events among family planning specialists: a cross sectional study","authors":"Taylor N. Weckstein, Rebecca G. Simmons, Jami Baayd, Kathryn E. Fay","doi":"10.1186/s12978-024-01870-6","DOIUrl":"https://doi.org/10.1186/s12978-024-01870-6","url":null,"abstract":"Proponents of abortion restriction cite advancements in contraceptive technology as a reason against the need for abortion care today, most recently through oral arguments in the Supreme Court of the United States case, Dobbs v. Jackson Women’s Health. However, consistent and correct use of contraception requires reproductive health literacy. Our objectives were to quantify contraceptive risk events and assess contraceptive history and preferences among a population well-equipped to evade contraceptive risks, family planning specialists following initiation of their medical training. “Risk events” are defined as reported episodes of contraceptive failure, emergency contraception use and/or unprotected or underprotected intercourse. This was a cross-sectional study among current members of a professional organization of family planning specialists. Inclusion criteria included: status as a current or retired clinician, consensual penile-vaginal intercourse and personal or partner capacity to become pregnant since the start of medical training. Descriptive statistics were performed. This study was IRB exempt. Among 229 respondents, 157 (69%) reported experiencing a contraceptive risk event since training. Twenty-nine (13%) respondents reported an occurrence within the last year. By category, 47% (108/229; 3 reported unknown) reported under- or unprotected intercourse, 35% (81/229) reported emergency contraception use, and 52% of participants (117/227; 2 unknown) reported known or suspected contraceptive failure. The mean number of contraceptive methods used was 3.7 (SD 1.7) out of the 13 methods listed. Almost all (97%) participants reported at least one method was not an acceptable option, with a mean of 5.6 (SD 2.7) of the 13 listed methods. The majority of family planning specialists have experienced contraceptive risk events during times of active pregnancy prevention since their medical training. Contraceptive method change is common and most respondents were limited in the number of methods that were personally acceptable to them. Dialogue idealizing the role of contraception in minimizing or eliminating abortion need is simplistic and inaccurately represents the lived realities of pregnancy-capable individuals and their partners, including among those with exceptional contraceptive literacy and access. Since Dobbs v. Jackson, the landmark Supreme Court of the United States case overturning the right to abortion, it is very important to better understand current birth control use and the risk of unintended pregnancy. While birth control helps people to avoid unintended pregnancy, current methods are not perfect. This study examined the limitations of current birth control, even when used by expert clinicians with special knowledge and access. We provided an online survey to doctors and advanced practice clinicians who specialize in birth control. We measured risk of unintended pregnancy by asking about experiences with birth control failure, e","PeriodicalId":20899,"journal":{"name":"Reproductive Health","volume":"31 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142185556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring women’s knowledge of abortion legality and association with source of abortion care using population-based survey data in Côte d’Ivoire and Ghana 利用科特迪瓦和加纳的人口调查数据,探讨妇女对堕胎合法性的认识及其与堕胎护理来源的关系
IF 3.4 2区 医学
Reproductive Health Pub Date : 2024-09-12 DOI: 10.1186/s12978-024-01871-5
Grace Sheehy, Caroline Moreau, Easmon Otupiri, Sarah Keogh, Georges Guiella, Suzanne O. Bell
{"title":"Exploring women’s knowledge of abortion legality and association with source of abortion care using population-based survey data in Côte d’Ivoire and Ghana","authors":"Grace Sheehy, Caroline Moreau, Easmon Otupiri, Sarah Keogh, Georges Guiella, Suzanne O. Bell","doi":"10.1186/s12978-024-01871-5","DOIUrl":"https://doi.org/10.1186/s12978-024-01871-5","url":null,"abstract":"Knowledge of the conditions under which abortion is legal is important so that people can advocate for their right to abortion care. Yet minimal research has explored the association between women’s knowledge of abortion legality and the induced abortion care they receive, particularly using population-based survey data. Using national survey data collected by Performance Monitoring for Action (PMA) in Côte d’Ivoire and Ghana, we aimed to compare the prevalence of accurate knowledge of abortion legality, factors associated with knowledge of the law, and the association between knowledge of abortion legality and the source of women’s induced abortion care in these two settings. We ran bivariate and multivariable logistic regressions to assess the relationships of interest. We found that awareness and knowledge of the abortion law were low in both Côte d’Ivoire and Ghana. In Cote d’Ivoire, women who were older, more educated, and with past abortion experience were more likely to be aware of the law. In Ghana, knowledge of the law did not vary significantly by demographic characteristics. However, in Ghana, knowledge of the law was correlated with women’s use of the formal healthcare system for abortion care, with greater use of clinical sources in rural areas. It is possible that for populations with reduced access to abortion services, such as those in rural areas, knowledge of the law is advantageous for those seeking facility-based abortion care, particularly in settings where abortion is legal for a range of indications. Interventions seeking to improve access to facility-based abortion care in settings where abortion is legal on various grounds should incorporate education on the legal grounds for abortion. Knowledge of the conditions under which abortion is legal is important for people to advocate for their right to abortion care, yet minimal research has explored the association between women’s knowledge of abortion legality and the abortion care they receive, particularly using population-based survey data. Using national survey data collected by Performance Monitoring for Action (PMA) in Côte d’Ivoire and Ghana, we aimed to compare the prevalence of accurate knowledge of abortion legality, factors associated with knowledge of the law, and the association between knowledge of abortion legality and the source of women’s abortion care in these two settings. We ran bivariate and multivariable logistic regressions to assess the relationships of interest. We found that awareness and knowledge of the abortion law were low in both Côte d’Ivoire and Ghana. In Côte d’Ivoire, knowledge was unequally distributed according to sociodemographic factors, while such inequities did not exist in Ghana. However, in Ghana, knowledge of the law was correlated with women’s use of the formal healthcare system for abortion care, with greater use of clinical sources in rural areas. It is possible that for populations with reduced access to abortion services, such ","PeriodicalId":20899,"journal":{"name":"Reproductive Health","volume":"2021 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142185554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring comprehensive sexuality education experiences and barriers among students, teachers and principals in Nepal: a qualitative study 探索尼泊尔学生、教师和校长的全面性教育经验和障碍:一项定性研究
IF 3.4 2区 医学
Reproductive Health Pub Date : 2024-09-11 DOI: 10.1186/s12978-024-01876-0
Sara Rivenes Lafontan, Felicia Jones, Niru Lama
{"title":"Exploring comprehensive sexuality education experiences and barriers among students, teachers and principals in Nepal: a qualitative study","authors":"Sara Rivenes Lafontan, Felicia Jones, Niru Lama","doi":"10.1186/s12978-024-01876-0","DOIUrl":"https://doi.org/10.1186/s12978-024-01876-0","url":null,"abstract":"Comprehensive sexuality education (CSE) is essential in empowering adolescents with the knowledge and confidence to manage their sexual and reproductive health. Despite its recognized benefits, access to quality CSE remains limited, especially in low-income countries, where societal norms and structural barriers hinder effective delivery. The aim of this study is to investigate the experiences and perceptions among students, teachers, and principals in Nepal about comprehensive sexuality education. Qualitative methods were used. 13 Semi-structured interviews and 1 focus group discussion were carried out with 15 teachers and principals working at higher secondary schools and two focus group discussions were conducted with a total of 13 adolescents. Thematic analysis was used to analyze the data. Four themes were developed: Resistance to Teaching and Learning, Preparation and Engagement Strategies, Taboos and Silencing and Structural Barriers. Students, teachers, principals and students reported discomfort and embarrassment when discussing sensitive topics, with gender dynamics playing a significant role. Strategies like warm-up sessions and continuous interaction with students and parents were used to create a supportive learning environment. However, socio-cultural barriers and family attitudes continued to hinder open discussions about sexuality. Structural barriers, including the lack of formal training for teachers and inadequate instructional materials, further impeded effective CSE delivery. The experiences of CSE in Nepal among students, teachers and principals highlight significant barriers including cultural taboos, gender dynamics and insufficient resources. Addressing these barriers through comprehensive teacher training, curriculum reform, and societal engagement is critical to ensure access to CSE.","PeriodicalId":20899,"journal":{"name":"Reproductive Health","volume":"5 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142185555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the link between chromosomal polymorphisms and reproductive abnormalities. 探索染色体多态性与生殖异常之间的联系。
IF 3.6 2区 医学
Reproductive Health Pub Date : 2024-09-05 DOI: 10.1186/s12978-024-01854-6
Haiyan Pang, Tong Zhang, Xin Yi, Xiaojing Cheng, Guiling Wang
{"title":"Exploring the link between chromosomal polymorphisms and reproductive abnormalities.","authors":"Haiyan Pang, Tong Zhang, Xin Yi, Xiaojing Cheng, Guiling Wang","doi":"10.1186/s12978-024-01854-6","DOIUrl":"10.1186/s12978-024-01854-6","url":null,"abstract":"<p><strong>Objective: </strong>This work aimed to investigate the potential correlation between chromosomal polymorphisms and various reproductive abnormalities.</p><p><strong>Methods: </strong>We examined 21,916 patients affected by infertility who sought care at the Department of Reproductive Medicine, Affiliated Hospital of Shandong Second Medical University between January 2018 and December 2022. A total of 2227 individuals identified as chromosomal polymorphism carriers constituted the polymorphism group, and 2245 individuals with normal chromosome karyotypes were randomly selected to form a control group. Clinical manifestations, histories of spontaneous miscarriage, abnormal reproductive developments, fetal abnormalities, and male sperm quality anomalies were statistically compared between these two groups.</p><p><strong>Results: </strong>Of the 21,916 patients analyzed, 2227 displayed chromosomal polymorphism, representing a 10.16% detection rate. Amongst the male patients, 1622 out of 10,827 exhibited polymorphisms (14.98%), whereas 605 out of 11,089 females showed polymorphisms (5.46%). Female carriers in the polymorphism group, showed statistically significant increased rates of spontaneous abortion (29.75% vs. 18.54%), fetal anomalies (1.32% vs. 0.81%), and uterine abnormalities compared with the control group (1.32% vs. 0.81%). Male carriers in the polymorphism group had higher rates of spontaneous abortion in partners (22.87% vs. 10.37%), fetal anomalies (1.97% vs. 0.25%), compromised sperm quality (41.74% vs. 7.18%), testicular underdevelopment (2.28% vs. 0.92%), and hypogonadotropic hypogonadism (0.62% vs. 0.37%) compared with the control group.</p><p><strong>Conclusion: </strong>Chromosomal polymorphisms may have a certain negative effect on reproductive irregularities, including spontaneous abortions, fetal anomalies, and reduced sperm quality in males. Their clinical effects deserve further investigation.</p>","PeriodicalId":20899,"journal":{"name":"Reproductive Health","volume":"21 1","pages":"130"},"PeriodicalIF":3.6,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11378481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is MIStreatment of women during facility-based childbirth an independent risk factor for POstpartum Depression in Ethiopia and Guinea? A mixed methods prospective study protocol-MISPOD study. 在埃塞俄比亚和几内亚,妇女在设施内分娩时受到的不当治疗是产后抑郁症的独立风险因素吗?混合方法前瞻性研究方案--MISPOD 研究。
IF 3.6 2区 医学
Reproductive Health Pub Date : 2024-09-04 DOI: 10.1186/s12978-024-01850-w
Anteneh Asefa, Samson Gebremedhin, Alexandre Delamou, Bruno Marchal, Lenka Benová
{"title":"Is MIStreatment of women during facility-based childbirth an independent risk factor for POstpartum Depression in Ethiopia and Guinea? A mixed methods prospective study protocol-MISPOD study.","authors":"Anteneh Asefa, Samson Gebremedhin, Alexandre Delamou, Bruno Marchal, Lenka Benová","doi":"10.1186/s12978-024-01850-w","DOIUrl":"10.1186/s12978-024-01850-w","url":null,"abstract":"<p><strong>Background: </strong>Worldwide, 10% of postpartum women experience postpartum depression, which can lead to diverse sequalae at individual, family, and societal levels. In sub-Saharan Africa, it is estimated that 17% of women experience depression in the postpartum period, which could be an underestimate as 48% of women in the region do not receive postnatal care (81% in Ethiopia and 51% in Guinea) and a large share of postpartum depression remains undiagnosed and untreated as a result. Globally, despite a critical evidence gap, there are growing reports of postpartum depression among women mistreated (disrespected and abused) during childbirth in health facilities, making a strong case to examine the association between mistreatment and postpartum depression. This study in Addis Ababa (Ethiopia) and Conakry (Guinea) uses a mixed methods design to 1) examine the link between mistreatment and postpartum depression, 2) explore the health system capacity to provide respectful maternity care and maternal mental health services, and 3) explore the experiences of women in accessing care and support for postpartum depression.</p><p><strong>Methods: </strong>We will conduct a prospective longitudinal survey of women (434 in Addis Ababa and 408 in Conakry) from the third trimester of pregnancy to eight weeks postpartum and carry out in-depth interviews with key health system informants (20-25 in each city) and women who recovered from a clinically confirmed episode of postpartum depression (15-25 in each city). Quantitative data from the women's survey will be analysed using a multilevel mixed-effects model; qualitative data from key-informants will be analysed by using a hybrid thematic analysis approach, whereas data from women's in-depth interviews will be analysed using the phenomenological approach. The inclusion of two different settings in our study (Addis Ababa and Conakry) will enable us to apply a comparative health systems lens to explore the dynamics of respectful maternity care and maternal mental health services within the broader health systems of the two countries (Ethiopia and Guinea).</p><p><strong>Discussion: </strong>The findings from this study will inform actions aimed at mitigating the mistreatment of women in maternity settings and improving promotive, preventive, and treatment interventions for postpartum depression in Ethiopia and Guinea. The findings can also be extrapolated to other low-resource settings.</p>","PeriodicalId":20899,"journal":{"name":"Reproductive Health","volume":"21 1","pages":"129"},"PeriodicalIF":3.6,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11375852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effects of a quality improvement project to reduce caesarean sections in selected private hospitals in Brazil. 巴西部分私立医院减少剖腹产的质量改进项目的效果。
IF 3.6 2区 医学
Reproductive Health Pub Date : 2024-09-04 DOI: 10.1186/s12978-024-01851-9
Maria do Carmo Leal, Rosa Maria Soares Madeira Domingues, Thaís Cristina Oliveira Fonseca, Tatiana Henriques Leite, Ana Claudia Figueiró, Ana Paula Esteves Pereira, Mariza Miranda Theme-Filha, Bárbara Vasques da Silva Ayres, Oliver Scott, Rita de Cássia Sanchez, Paulo Borem, Maria Carolina de Maio Osti, Marcos Wengrover Rosa, Amanda S Andrade, Fernando Maia Peixoto Filho, Marcos Nakamura-Pereira, Jacqueline Alves Torres
{"title":"The effects of a quality improvement project to reduce caesarean sections in selected private hospitals in Brazil.","authors":"Maria do Carmo Leal, Rosa Maria Soares Madeira Domingues, Thaís Cristina Oliveira Fonseca, Tatiana Henriques Leite, Ana Claudia Figueiró, Ana Paula Esteves Pereira, Mariza Miranda Theme-Filha, Bárbara Vasques da Silva Ayres, Oliver Scott, Rita de Cássia Sanchez, Paulo Borem, Maria Carolina de Maio Osti, Marcos Wengrover Rosa, Amanda S Andrade, Fernando Maia Peixoto Filho, Marcos Nakamura-Pereira, Jacqueline Alves Torres","doi":"10.1186/s12978-024-01851-9","DOIUrl":"10.1186/s12978-024-01851-9","url":null,"abstract":"<p><strong>Background: </strong>Brazil is one of the countries with the highest rates of caesarean sections (CS), reaching almost 90% of births in the private sector. A quality improvement project called \"Adequate Childbirth Project (PPA)\" was conceived to reduce CS in the private sector. This project consisted of four primary components: \"Governance\", \"Participation of Women\", \"Reorganization of Care\" and \"Monitoring\". This paper aims to evaluate: (1) which specific activities of the PPA had the largest effect on the probability of a woman having a vaginal delivery; (2) which primary component of the PPA had the largest effect on the probability of vaginal delivery and (3) which scenarios combining the implementation of different activities planned in the PPA had a higher effect on the probability of vaginal delivery.</p><p><strong>Methods: </strong>A sample of 12 private hospitals participating in the PPA was evaluated. We used a Bayesian Network (BN) to capture both non-linearities and complex cause-effect relations. The BN integrated knowledge from experts and data from women to estimate 26 model parameters. The PPA was evaluated in 2473 women belonging to groups 1-4 of the Robson classification, who were divided into two groups: those participating or not participating in the PPA.</p><p><strong>Results: </strong>The probability of a woman having a vaginal delivery was 37.7% higher in women participating in the PPA. The most important component of the project that led to an increase in the probability of vaginal delivery was \"Reorganization of Care\", leading to a 73% probability of vaginal delivery among women in labor. The activity that had the greatest effect on the type of delivery was access to best practices during labor, with a 72% probability of vaginal delivery. Considering the 12 scenarios combining the different activities of the PPA, the best scenarios included: a non-scheduled delivery, access to information about best practices, access to at least 4 best practices during labor and respect of the birth plan, with an 80% probability of vaginal delivery in the best combinations.</p><p><strong>Conclusion: </strong>PPA has been shown to be an effective quality improvement program, increasing the likelihood of vaginal delivery in private Brazilian hospitals.</p>","PeriodicalId":20899,"journal":{"name":"Reproductive Health","volume":"20 Suppl 2","pages":"194"},"PeriodicalIF":3.6,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11375826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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