Radiology最新文献

{"title":"Granular Insights into Myocardial Scarring: Advancing Risk Stratification in Ischemic Cardiomyopathy.","authors":"João A C Lima, Elnaz Ebrahimihoor","doi":"10.1148/radiol.243672","DOIUrl":"https://doi.org/10.1148/radiol.243672","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"314 1","pages":"e243672"},"PeriodicalIF":12.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142954068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantification of Vascular Remodeling and Sinusoidal Capillarization to Assess Liver Fibrosis with Photoacoustic Imaging.","authors":"Wenya Li, Jing Lv, Honghui Li, Liwen Song, Rui Zhang, Xingyang Zhao, Feichao Xuan, Tong Sun, Kai Long, Yinghua Zhao, Liming Nie","doi":"10.1148/radiol.241275","DOIUrl":"https://doi.org/10.1148/radiol.241275","url":null,"abstract":"<p><p>Background Photoacoustic microscopy (PAM) can be used to detect strong absorption from endogenous and exogenous contrast material, making it promising for detailed structural and functional imaging of hepatic sinusoids, including dynamic visualization of permeability. Purpose To evaluate whether PAM-based quantitative parameters of liver function and integrity (lacunarity, blood oxygen saturation [Sao₂], and Evans blue [EB] permeability) are associated with histopathologic indexes of fibrosis in a mouse model. Materials and Methods Between October 2022 and July 2023, a total of 35 male C57BL/6 mice were included in this study and received intraperitoneal injection of carbon tetrachloride to establish mouse models of progressive liver fibrosis, with seven mice in each group. PAM was performed to visualize vascular structure, Sao₂ distribution, and EB penetration within the hepatic lobule. Histologic findings were used as the reference standard. Associations between the PAM parameters and the pathologic results were evaluated with Spearman rank correlation. Results Mean lacunarity, a PAM parameter, gradually increased with liver fibrosis stage (control: 0.018 arbitrary units [au] ± 0.004 [SD]; fibrosis: 1 week, 0.024 au ± 0.002; 2 weeks, 0.028 au ± 0.003; 4 weeks, 0.034 au ± 0.002; 10 weeks, 0.040 au ± 0.005; <i>P</i> < .001) and was positively correlated with collagen-positive area (Spearman <i>r</i> = 0.88-0.90; <i>P</i> < .001). PAM revealed that Sao₂ decreased with disease progression (control, 0.921 au ± 0.017; 1 week, 0.875 au ± 0.019; 2 weeks, 0.846 au ± 0.020; 4 weeks, 0.802 au ± 0.025; 10 weeks, 0.732 au ± 0.036; <i>P</i> < .001) and was inversely related to hypoxia-inducible factor 1α expression (Spearman <i>r</i> = -0.83; <i>P</i> < .001). EB permeability, indicative of hepatic sinusoid capillarization, was reduced at advanced stages of fibrosis (control: 11.6% [IQR, 11.2%-11.8%]; fibrosis: 1 week, 24.8% [IQR, 23.3%-25.8%]; 2 weeks, 18.4% [IQR, 18.4%-20.0%]; 4 weeks, 5.1% [IQR, 4.9%-6.2%]; 10 weeks, 3.7% [IQR, 3.4%-4.5%]; <i>P</i> < .001). Conclusion PAM-based structural and functional parameters were associated with liver fibrosis severity, and PAM imaging of EB dynamics helped detect sinusoidal capillarization. © RSNA, 2025 <i>Supplemental material is available for this article.</i> See also the editorial by Li and Yao in this issue.</p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"314 1","pages":"e241275"},"PeriodicalIF":12.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leveraging GPT-4 as a Proofreader: Addressing the Growing Workload of Radiologists.","authors":"Yangsean Choi","doi":"10.1148/radiol.243859","DOIUrl":"https://doi.org/10.1148/radiol.243859","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"314 1","pages":"e243859"},"PeriodicalIF":12.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance Tests for Automation Routines in Radiology.","authors":"Mark P Langer","doi":"10.1148/radiol.250043","DOIUrl":"https://doi.org/10.1148/radiol.250043","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"314 1","pages":"e250043"},"PeriodicalIF":12.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep Learning Superresolution for Simultaneous Multislice Parallel Imaging-Accelerated Knee MRI Using Arthroscopy Validation.","authors":"Sven S Walter, Jan Vosshenrich, Tatiane Cantarelli Rodrigues, Danoob Dalili, Benjamin Fritz, Richard Kijowski, Eun Hae Park, Aline Serfaty, Steven E Stern, Inge Brinkmann, Gregor Koerzdoerfer, Jan Fritz","doi":"10.1148/radiol.241249","DOIUrl":"https://doi.org/10.1148/radiol.241249","url":null,"abstract":"<p><p>Background Deep learning (DL) methods can improve accelerated MRI but require validation against an independent reference standard to ensure robustness and accuracy. Purpose To validate the diagnostic performance of twofold-simultaneous-multislice (SMSx2) twofold-parallel-imaging (PIx2)-accelerated DL superresolution MRI in the knee against conventional SMSx2-PIx2-accelerated MRI using arthroscopy as the reference standard. Materials and Methods Adults with painful knee conditions were prospectively enrolled from December 2021 to October 2022. Participants underwent fourfold SMSx2-PIx2-accelerated standard-of-care and investigational DL superresolution MRI at 3 T. Seven radiologists independently evaluated the MRI examinations for overall image quality (using Likert scale scores: 1, very bad, to 5, very good) and the presence or absence of meniscus and ligament tears. Articular cartilage was categorized as intact, or partial or full-thickness defects. Statistical analyses included interreader agreements (Cohen κ and Gwet AC2) and diagnostic performance testing used area under the receiver operating characteristic curve (AUC) values. Results A total of 116 adults (mean age, 45 years ± 15 [SD]; 74 men) who underwent arthroscopic surgery within 38 days ± 22 were evaluated. Overall image quality was better for DL superresolution MRI (median Likert score, 5; range, 3-5) than conventional MRI (median Likert score, 4; range, 3-5) (<i>P</i> < .001). Diagnostic performances of conventional versus DL superresolution MRI were similar for medial meniscus tears (AUC, 0.94 [95% CI: 0.89, 0.97] vs 0.94 [95% CI: 0.90, 0.98], respectively; <i>P</i> > .99), lateral meniscus tears (AUC, 0.85 [95% CI: 0.78, 0.91] vs 0.87 [95% CI: 0.81, 0.94], respectively; <i>P</i> = .96), and anterior cruciate ligament tears (AUC, 0.98 [95% CI: 0.93, >0.99] vs 0.98 [95% CI: 0.93, >0.99], respectively; <i>P</i> > .99). DL superresolution MRI (AUC, 0.78; 95% CI: 0.75, 0.81) had higher diagnostic performance than conventional MRI (AUC, 0.71; 95% CI: 0.67, 0.74; <i>P</i> = .002) for articular cartilage lesions. DL superresolution MRI did not introduce hallucinations or erroneously omit abnormalities. Conclusion Compared with conventional SMSx2-PIx2-accelerated MRI, fourfold SMSx2-PIx2-accelerated DL superresolution MRI in the knee provided better image quality, similar performance for detecting meniscus and ligament tears, and improved performance for depicting articular cartilage lesions. © RSNA, 2025 <i>Supplemental material is available for this article.</i> See also the editorial by Nevalainen in this issue.</p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"314 1","pages":"e241249"},"PeriodicalIF":12.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editor's Recognition Awards.","authors":"Linda Moy","doi":"10.1148/radiol.243298","DOIUrl":"https://doi.org/10.1148/radiol.243298","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"314 1","pages":"e243298"},"PeriodicalIF":12.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142979746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges and Advances in Management of Acute Isolated Extracranial Internal Carotid Artery Occlusions.","authors":"Badih Junior Daou, Neeraj Chaudhary","doi":"10.1148/radiol.243753","DOIUrl":"https://doi.org/10.1148/radiol.243753","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"314 1","pages":"e243753"},"PeriodicalIF":12.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143010653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How I Do It: Management of Pleural-attached Pulmonary Nodules in Low-Dose CT Screening for Lung Cancer.","authors":"Yeqing Zhu, David F Yankelevitz, Claudia I Henschke","doi":"10.1148/radiol.240091","DOIUrl":"https://doi.org/10.1148/radiol.240091","url":null,"abstract":"<p><p>Lung cancer is the leading cause of cancer deaths globally. In various trials, the ability of low-dose CT screening to diagnose early lung cancers leads to high cure rates. It is widely accepted that the potential benefits of low-dose CT screening for lung cancer outweigh the harms. The ability to reliably predict the benignity of nodules, especially at the baseline round, further reduces the potential for harm. Pleural-attached nodules are an important subgroup that represents nodules attached (distance from any pleural surface, 0 mm) to any pleural surfaces (fissural, costal, mediastinal, and diaphragmatic). Pleural-attached solid nodules less than 10 mm in average diameter with smooth margins and triangular, lentiform, oval, or semicircular shapes have a high likelihood of benignity. The 2019 Lung CT Screening Reporting and Data System (Lung-RADS) version 1.1 assigned pleural-attached nodules with these features to categories 3 (probably benign, recommend follow-up in 6 months) or 4 (suspicious for malignancy, recommend follow-up in 3 months or PET/CT). However, Lung-RADS version 2022 now recommends annual follow-up rather than short-term follow-up. These changes downgrade these nodules to category 2 (benign) and limits additional workup. This review article summarizes the terminology used to describe these nodules, characteristics for determining benignity, and the accuracy of the evidence used to make these recommendations.</p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"314 1","pages":"e240091"},"PeriodicalIF":12.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143010691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MRI of the Rectum: A Decade into DISTANCE, Moving to DISTANCED.","authors":"Stephanie Nougaret, Kirsten Gormly, Doenja M J Lambregts, Caroline Reinhold, Vicky Goh, Elena Korngold, Quentin Denost, Gina Brown","doi":"10.1148/radiol.232838","DOIUrl":"10.1148/radiol.232838","url":null,"abstract":"<p><p>Over the past decade, advancements in rectal cancer research have reshaped treatment paradigms. Historically, treatment for locally advanced rectal cancer has focused on neoadjuvant long-course chemoradiotherapy, followed by total mesorectal excision. Interest in organ preservation strategies has been strengthened by the introduction of total neoadjuvant therapy with improved rates of complete clinical response. The administration of systemic induction chemotherapy and consolidation chemoradiotherapy in the neoadjuvant setting has introduced a new dimension to the treatment landscape and patients now face a more intricate decision-making process, given the expanded therapeutic options. This complexity underlines the importance of shared decision-making and brings to light the crucial role of radiologists. MRI, especially high-spatial-resolution T2-weighted imaging, is heralded as the reference standard for rectal cancer management because of its exceptional ability to provide staging and prognostic insights. A key evolution in MRI interpretation for rectal cancer is the transition from the DISTANCE mnemonic to the more encompassing DISTANCED-DIS, distal tumor boundary; T, T stage; A, anal sphincter complex; N, nodal status; C, circumferential resection margin; E, extramural venous invasion; D, tumor deposits. This nuanced shift in the mnemonic captures a wider range of diagnostic indicators. It also emphasizes the escalating role of radiologists in steering well-informed decisions in the realm of rectal cancer care.</p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"314 1","pages":"e232838"},"PeriodicalIF":12.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142954069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling Inner Doubts beyond ChatGPT's Apparent Overconfidence.","authors":"Aghiles Hamroun, Philippe Amouyel, Raphaël Bentegeac, Gregory Kuchcinski, Bastien Le Guellec","doi":"10.1148/radiol.241766","DOIUrl":"https://doi.org/10.1148/radiol.241766","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"314 1","pages":"e241766"},"PeriodicalIF":12.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143010697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}