Research and Practice in Thrombosis and Haemostasis最新文献_第5页

167 Optimizing Perioperative Anticoagulation Management: Impact of a Clinical Pharmacist Practitioner Managed Clinic on Patient Safety and Care Quality 167优化围手术期抗凝管理：临床药师管理的诊所对患者安全和护理质量的影响

IF 3.4 3区医学

Research and Practice in Thrombosis and Haemostasis Pub Date : 2025-05-01 DOI: 10.1016/j.rpth.2025.102795

Ruby O. Doan , April Y. Allen

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149 Social Determinants of Health Barriers within an Antithrombosis Clinic 抗血栓诊所内健康障碍的149个社会决定因素

IF 3.4 3区医学

Research and Practice in Thrombosis and Haemostasis Pub Date : 2025-05-01 DOI: 10.1016/j.rpth.2025.102774

Hannah Ayers , Karen C. Thomas , Lauren Wilcox , Ellen Uppuluri

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152 Improving the Anticoagulation Program Enrollment Process: A Collaboration between Unlicensed Assistive Personnel and Registered Nurses to Improve Practice and Patient Care 152改善抗凝项目注册流程：无证辅助人员和注册护士之间的合作，以改善实践和患者护理

IF 3.4 3区医学

Research and Practice in Thrombosis and Haemostasis Pub Date : 2025-05-01 DOI: 10.1016/j.rpth.2025.102807

Kristin D.F. Negley , Gina M. Foster , Robin Beaupre , Kelly Breck , Amanda Schulz , Marissa Ruechel , Desiree Neumann

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Neonatal intracardiac thrombosis secondary to transplacental transfer of maternal antiphospholipid antibodies-a case report and review of the literature 新生儿心内血栓形成继发于母体抗磷脂抗体经胎盘移植- 1例报告和文献复习

IF 3.4 3区医学

Research and Practice in Thrombosis and Haemostasis Pub Date : 2025-05-01 DOI: 10.1016/j.rpth.2025.102895

Katherine Girgulis , Leslie Skeith , Deborah Fruitman , Megan Barber , Nancy Soliman , Nicole Johnson , Macgregor Steele

{"title":"Neonatal intracardiac thrombosis secondary to transplacental transfer of maternal antiphospholipid antibodies-a case report and review of the literature","authors":"Katherine Girgulis , Leslie Skeith , Deborah Fruitman , Megan Barber , Nancy Soliman , Nicole Johnson , Macgregor Steele","doi":"10.1016/j.rpth.2025.102895","DOIUrl":"10.1016/j.rpth.2025.102895","url":null,"abstract":"<div><h3>Background</h3><div>Maternal antiphospholipid immunoglobulin (Ig) G antibodies can cross the placenta, placing neonates at uncertain risk for thrombosis. There are no previous reports of neonatal intracardiac thrombosis (ICT) in the context of anticardiolipin antibodies (aCL).</div></div><div><h3>Key Clinical Question</h3><div>What were the clinical manifestations, management, and outcomes for a mother and her child with ICT secondary to presumed transplacental transfer of aCL?</div></div><div><h3>Clinical Approach</h3><div>A 2-week-old female presented with reduced feeding and was found to be poorly perfused with significant lactic acidosis. A mobile mass was noted near the left atrial appendage on the echocardiogram and confirmed on cardiac magnetic resonance imaging. Magnetic resonance imaging of the brain was normal, with no evidence of stroke. The aCL IgG titers returned highly positive for the infant (115.3 IgG phospholipid (GPL)-Unit [U]/mL) and mother (>160 GPL-U/mL; >99th percentile local reference is ≥20 GPL-U/mL). There were no other overt risk factors for thrombosis. The infant received 6 months of enoxaparin until aCL normalized. There remains a small calcified thrombus adherent to the left atrial wall. At 2 years old, the child remains healthy with no cardiac, neurologic, nor thrombotic sequelae.</div></div><div><h3>Conclusion</h3><div>This is the first report of neonatal ICT presumed secondary to maternal aCL. The outcome was favorable with anticoagulation management. Further research is needed in the area of transplacental antiphospholipid antibody transfer, identification of neonates at risk, and optimal clinical management.</div></div>","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 4","pages":"Article 102895"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144231670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

External validation of the DAYS score for suspected deep vein thrombosis 疑似深静脉血栓的DAYS评分的外部验证

IF 3.4 3区医学

Research and Practice in Thrombosis and Haemostasis Pub Date : 2025-05-01 DOI: 10.1016/j.rpth.2025.102885

Thor–David Halstensen , Camilla Hardeland , Waleed Ghanima , Vigdis Abrahamsen Grøndahl , Aliaksandr Hubin , Camilla Tøvik Jørgensen , Kerstin de Wit , Mazdak Tavoly

{"title":"External validation of the DAYS score for suspected deep vein thrombosis","authors":"Thor–David Halstensen , Camilla Hardeland , Waleed Ghanima , Vigdis Abrahamsen Grøndahl , Aliaksandr Hubin , Camilla Tøvik Jørgensen , Kerstin de Wit , Mazdak Tavoly","doi":"10.1016/j.rpth.2025.102885","DOIUrl":"10.1016/j.rpth.2025.102885","url":null,"abstract":"<div><h3>Background</h3><div>Diagnosing deep vein thrombosis (DVT) involves clinical assessment, D-dimer testing, and imaging. The DAYS score, a novel 2-item prediction tool combined with D-dimer, demonstrated promising performance but required external validation.</div></div><div><h3>Objectives</h3><div>This study aimed to validate 2 DVT prediction scores: the DAYS score and a newly developed DVT score.</div></div><div><h3>Methods</h3><div>Data were collected from a prospective Norwegian DVT management study (2015-2018; NCT02486445). The DAYS score includes 2 items (DVT most likely diagnosis and calf swelling), while the new score comprises tenderness along the deep veins and previous venous thromboembolism. DVT was considered excluded if no items were present and D-dimer was < 1.0 μg/mL or if ≥1 item was present and D-dimer was < 0.5 μg/mL. The 2-tier Wells score served as the reference. Safety was defined as the number of missed DVT cases divided by the total number of patients classified as having DVT excluded and was set at 2%.</div></div><div><h3>Results</h3><div>Among 1312 patients (median age, 64 years; IQR, 52-73 years; 55% women), 261 (20.0%) had confirmed DVT. The DAYS score excluded DVT in 455 patients (34.6%), of whom 11 were diagnosed with DVT (failure rate, 2.4 %; 95% CI, 1.2-4.2). The new score excluded DVT in 519 patients (39.6%) and missed 7 cases with confirmed DVT (failure rate, 1.3%; 95% CI, 0.5-2.8). The Wells score excluded DVT in 271 patients (20.6%), missing only 2 cases with confirmed DVT.</div></div><div><h3>Conclusion</h3><div>While both the DAYS score and the new score demonstrated low failure rates, they exceeded the predefined safety threshold.</div></div>","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 4","pages":"Article 102885"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144306950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identifying and addressing underuse in hematologic care through systems-based hematology 通过以系统为基础的血液学来识别和解决血液学护理的不足

IF 3.4 3区医学

Research and Practice in Thrombosis and Haemostasis Pub Date : 2025-05-01 DOI: 10.1016/j.rpth.2025.102881

Jacob C. Cogan , Allison E. Burnett , Alexandra Power-Hays , Geoffrey D. Barnes , Ming Y. Lim

引用次数: 0

80 Thrombophilia Screening in Inpatients: A Review of Testing Appropriateness and Clinical Impact in a Tertiary Hospital in Qatar 住院患者的血栓筛查：卡塔尔一家三级医院检测适宜性和临床影响的回顾

IF 3.4 3区医学

Research and Practice in Thrombosis and Haemostasis Pub Date : 2025-05-01 DOI: 10.1016/j.rpth.2025.102801

Osama Abdelsamad , Dania Alkhiyami , Syed Yameen Hasan , Eman Alhmoud , Rasha Al Anany

引用次数: 0

158 Clinical Performance of a Novel Point-of-Care Coagulometer, the Perosphere ClotChek™, for the DOACS 用于DOACS的新型即时凝血仪Perosphere ClotChek™的临床性能

IF 3.4 3区医学

Research and Practice in Thrombosis and Haemostasis Pub Date : 2025-05-01 DOI: 10.1016/j.rpth.2025.102786

S.H. Bakhru , X. Jiang , L. Chen , D. Osmani , A. Balaj , K. Kronen , D. Mootoo , F. LaDuca , J. Ansell

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190 Patient Compliance with Aspirin and Rivaroxaban Post Elective Joint Replacement Surgery: A Quality Assurance Initiative 选择性关节置换手术后患者对阿司匹林和利伐沙班的依从性：一项质量保证倡议

IF 3.4 3区医学

Research and Practice in Thrombosis and Haemostasis Pub Date : 2025-05-01 DOI: 10.1016/j.rpth.2025.102811

Laurie A. Sardo , Julia A. Bayadinova , Emma K. Sardo

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144 Anticoagulation in Patients with Provoked Venous Thromboembolism: A Real-World Analysis of Clinical Characteristics, Management Strategies, and Outcomes from an Outpatient Tertiary Anticoagulation Clinic in Qatar 诱发性静脉血栓栓塞患者的抗凝治疗：卡塔尔一家三级抗凝门诊的临床特征、管理策略和结果分析

IF 3.4 3区医学

Research and Practice in Thrombosis and Haemostasis Pub Date : 2025-05-01 DOI: 10.1016/j.rpth.2025.102827

Ibtihal Mahmoud Abdallah , Asma Eltahir , Rana Moustafa Al-Adawi , Mohamed Abdelgelil , Abdul Moqeeth Mohammed , Asmaa Mohamed

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