Research and Practice in Thrombosis and Haemostasis最新文献

{"title":"153 Implementation of a Clinical Surveillance Tool for Direct Oral Anticoagulation Monitoring in the Outpatient Setting","authors":"Kosha Patel , Alissa Nathans , Drew Armstrong , Jennifer Campbell","doi":"10.1016/j.rpth.2025.102757","DOIUrl":"10.1016/j.rpth.2025.102757","url":null,"abstract":"","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 ","pages":"Article 102757"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"129 Risk Mitigation of Gastrointestinal Bleeding in Patients Co-Prescribed Antiplatelets with Oral Anticoagulants: VISN 8 Anticoagulation Stewardship Proton Pump Inhibitor Initiative","authors":"David Parra , Jeffery L. Kibert II , Natalie R. Ciccone , Litzalee Camacho-Vega , Joseph Capriola , Jennifer L. Crowley , Joseph J. Fierro , Alida Marrero-Hernandez , Maria J. Irias , Robert D. Stewart , Jaclyn Stoppi , Elyse C. Wilson , Laura K. Vinieratos , VISN 8 Pharmacy Anticoagulation Workgroup","doi":"10.1016/j.rpth.2025.102752","DOIUrl":"10.1016/j.rpth.2025.102752","url":null,"abstract":"","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 ","pages":"Article 102752"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"97 Assessment of Patient's Knowledge and Its Impact on Achieving Therapeutic International Normalized Ratio Goal","authors":"Reema Syed","doi":"10.1016/j.rpth.2025.102740","DOIUrl":"10.1016/j.rpth.2025.102740","url":null,"abstract":"","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 ","pages":"Article 102740"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"63 Increased Neonatal Mortality and Increasing Rate of Cerebral Venous Sinus Thrombosis in Hospitalized Children: A Pediatric Health Information System Database Study","authors":"Jiasen He , Natalie Montanez , Stuart Fraser , Audrey Barnett , Christin Silos , Keely Smith , Lakshmi Srivaths","doi":"10.1016/j.rpth.2025.102792","DOIUrl":"10.1016/j.rpth.2025.102792","url":null,"abstract":"","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 ","pages":"Article 102792"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"164 Safety and Efficacy of the Use of Direct Oral Anticoagulants in Patients with a History of Bariatric Surgery","authors":"Nicholas Shabanowitz , Kayla Popova , Michelle Schultz , Nghi Ha","doi":"10.1016/j.rpth.2025.102821","DOIUrl":"10.1016/j.rpth.2025.102821","url":null,"abstract":"","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 ","pages":"Article 102821"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guidelines for management of hemophilia—why, what, and how?","authors":"Alok Srivastava , Johnny Mahlangu , Steven W. Pipe","doi":"10.1016/j.rpth.2025.102879","DOIUrl":"10.1016/j.rpth.2025.102879","url":null,"abstract":"","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 4","pages":"Article 102879"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144139489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inhibitor development in nonsevere hemophilia: data from the European Haemophilia Safety Surveillance (EUHASS) registry","authors":"Kathelijn Fischer ,&nbsp;Riitta Lassila ,&nbsp;Flora Peyvandi ,&nbsp;Alexander Gatt ,&nbsp;Samantha C. Gouw ,&nbsp;Robert Hollingsworth ,&nbsp;Thierry Lambert ,&nbsp;Radek Kaczmarek ,&nbsp;Diana Carbonero Alvarez ,&nbsp;Michael Makris ,&nbsp;EUHASS participants","doi":"10.1016/j.rpth.2025.102887","DOIUrl":"10.1016/j.rpth.2025.102887","url":null,"abstract":"<div><h3>Background</h3><div>Information on inhibitor development in nonsevere hemophilia and its association with clotting factor concentrate type is limited.</div></div><div><h3>Objectives</h3><div>To assess inhibitor development in patients with nonsevere hemophilia A (HA) and hemophilia B (HB) in the European Haemophilia Safety Surveillance system.</div></div><div><h3>Methods</h3><div>Inhibitors and total treated patients are reported annually. Any exposure to concentrate per year was considered a treatment year. Incidence rates per 1000 treatment years and 95% CIs were calculated according to type of concentrate and compared using incidence rate ratios (IRRs).</div></div><div><h3>Results</h3><div>During 2008 to 2023, 90 centers reported on 36,074 (HA) and 9238 (HB) treatment years. The inhibitor rate for nonsevere HA receiving factor (F)VIII was 4.2 per 1000 treatment years (95% CI, 3.5-4.9). Inhibitors developed at median 47.5 years (P25-P75 [IQR], 17.0-69.0), after median 40 exposure days (EDs; IQR, 17-80), with 58% occurring &lt;50 EDs and 88% &lt;100 EDs. Overall, 4 of 149 (2.7%) patients in the inhibitor group were female. Only one inhibitor was reported in nonsevere HB, in a female patient (FIX 7%, after 6 EDs), resulting in an inhibitor rate of 0.1 per 1000 treatment years (95% CI, 0.0-0.6). Compared with standard half-life recombinant FVIII, inhibitor rates on both plasma-derived FVIII (IRR, 0.27; 95% CI, 0.11-0.58; <em>P</em> &lt; .001) and extended half-life FVIII (IRR, 0.18; 95% CI, 0.02-0.68; <em>P</em> = .002) were significantly reduced.</div></div><div><h3>Conclusion</h3><div>Inhibitors in nonsevere hemophilia occurred at a rate of 4.2 per 1000 treatment years in HA and 0.1 per 1000 treatment years in HB. Compared with standard half-life FVIII, inhibitor development on plasma-derived and extended half-life FVIII were reduced. These data show that inhibitor monitoring is relevant with nonsevere HA in both sexes and should be continued lifelong.</div></div>","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 4","pages":"Article 102887"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144241052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Title page","authors":"","doi":"10.1016/S2475-0379(25)00228-6","DOIUrl":"10.1016/S2475-0379(25)00228-6","url":null,"abstract":"","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 ","pages":"Article 102904"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"131 Evaluation of Hemoglobin Monitoring Frequency in Patients on Anticoagulation Therapy","authors":"Liana Ha ,&nbsp;Saira Mirza ,&nbsp;Alyssa E. Utz ,&nbsp;Salman Hasham ,&nbsp;Mikhail Y. Akbashev","doi":"10.1016/j.rpth.2025.102784","DOIUrl":"10.1016/j.rpth.2025.102784","url":null,"abstract":"","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 ","pages":"Article 102784"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"130 Point-of-Care INR Monitoring for Patients with Antiphospholipid Syndrome","authors":"Morgan T. Quinn ,&nbsp;Tara Mohit ,&nbsp;Amy Hebbard ,&nbsp;Rebecca Chapin ,&nbsp;Brittany Cogdill","doi":"10.1016/j.rpth.2025.102789","DOIUrl":"10.1016/j.rpth.2025.102789","url":null,"abstract":"","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 ","pages":"Article 102789"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}