Psychiatry Research最新文献_第8页

Reducing mental health distress and preventing depression in young people in the community: A multimethod observational study with a real-world and prospective 12-month controlled approach 减少社区年轻人的心理健康困扰和预防抑郁症：一项多方法观察性研究，采用现实世界和前瞻性12个月的对照方法：社区年轻人的心理健康困扰。

IF 4.2 2区医学

Psychiatry Research Pub Date : 2025-02-01 DOI: 10.1016/j.psychres.2024.116279

Christy Lai-Ming Hui , Eric Yu-Hai Chen , Stephanie Ming-Yin Wong , Gloria Hoi-Yan Wong , Sherry Kit-Wa Chan , Pak-Chung Sham , Michael Tak-Hing Wong , Kai-Tai Chan , Charlton Cheung , Gabriel Chun-Hei Lai , Debra Rickwood , Patrick D Mcgorry , Yi-Nam Suen

{"title":"Reducing mental health distress and preventing depression in young people in the community: A multimethod observational study with a real-world and prospective 12-month controlled approach","authors":"Christy Lai-Ming Hui , Eric Yu-Hai Chen , Stephanie Ming-Yin Wong , Gloria Hoi-Yan Wong , Sherry Kit-Wa Chan , Pak-Chung Sham , Michael Tak-Hing Wong , Kai-Tai Chan , Charlton Cheung , Gabriel Chun-Hei Lai , Debra Rickwood , Patrick D Mcgorry , Yi-Nam Suen","doi":"10.1016/j.psychres.2024.116279","DOIUrl":"10.1016/j.psychres.2024.116279","url":null,"abstract":"<div><div>Community-based youth mental health (YMH) platforms are challenging to evaluate. Using a multi-method approach, we examined the efficacy of an integrated YMH program in Hong Kong. The real-world outcomes of 1047 participants were compared with a propensity score (PS) matched control group randomly selected from the community (study 1). In a separate prospective 12-month study, a sample of up to 133 matched pairs of YMH and controls were compared for more detailed symptomatic and functional outcomes (study 2). Study 1 revealed that the YMH program was associated with a significant reduction in distress. A higher proportion of YMH participants improved, and fewer deteriorated compared with controls. The YMH program also translated into a net reduction of 1.28 % in the risk of common disorders. Study 2 revealed that the YMH program showed significant reductions in depressive symptoms, anxiety symptoms, distress, and functioning after 12 months. The two complementary studies, using PS-matched controlled comparisons, enabled the sample representativeness and the comprehensive examination of the longitudinal impact. This YMH program reduces current distress, symptoms, and functional impairment, and prevents the emergence of probable mental disorder. Findings have significant implications for developing and evaluating future YMH services.</div></div>","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"344 ","pages":"Article 116279"},"PeriodicalIF":4.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Decisional capacity to consent to treatment in children and adolescents: A systematic review 儿童和青少年同意治疗的决策能力：系统综述。

IF 4.2 2区医学

Psychiatry Research Pub Date : 2025-02-01 DOI: 10.1016/j.psychres.2024.116343

Giovanna Parmigiani , Marcello Benevento , Biagio Solarino , Anna Margari , Davide Ferorelli , Luigi Buongiorno , Roberto Catanesi , Felice Carabellese , Antonio Del Casale , Stefano Ferracuti , Gabriele Mandarelli

{"title":"Decisional capacity to consent to treatment in children and adolescents: A systematic review","authors":"Giovanna Parmigiani , Marcello Benevento , Biagio Solarino , Anna Margari , Davide Ferorelli , Luigi Buongiorno , Roberto Catanesi , Felice Carabellese , Antonio Del Casale , Stefano Ferracuti , Gabriele Mandarelli","doi":"10.1016/j.psychres.2024.116343","DOIUrl":"10.1016/j.psychres.2024.116343","url":null,"abstract":"<div><div>Obtaining informed consent in vulnerable populations like children and adolescents, is a relevant issue and raises ethical concerns. Minors are considered unable to consent to treatment, and permission from guardians is required for them. Nevertheless, several studies have been carried out on the competence of pediatric patients, with mixed results. Following PRISMA guidelines, a systematic review was performed to assess children and adolescents’ decisional capacity to consent to treatment. The search strategy identified 2,790 studies, including 10 that survived full-text screening and evaluation. Studies included in the analysis evaluated the decision-making capacity of minors using the MacArthur Competency Assessment Tool - Treatment (MacCAT-T), the Adolescent Psychiatric Patient Competency Questionnaire (CQ-ChP); the Measure of Competency (MOC), the Measure of Competency- Hypothetical (MOC<img>Hyp). Overall, minors over the age of 13 showed an acceptable decisional capacity. However, further research, preferably on larger groups, is needed to shed more light on this topic.</div></div>","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"344 ","pages":"Article 116343"},"PeriodicalIF":4.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dissociative episodes and concurrent heart rate in patients with PTSD – An ecological momentary assessment 创伤后应激障碍患者的分离性发作和并发心率--生态瞬间评估。

IF 4.2 2区医学

Psychiatry Research Pub Date : 2025-02-01 DOI: 10.1016/j.psychres.2024.116345

Sarah Beutler-Traktovenko , Marcel Franz , Judith Daniels , Julia Schellong , Kerstin Weidner , Ilona Croy

{"title":"Dissociative episodes and concurrent heart rate in patients with PTSD – An ecological momentary assessment","authors":"Sarah Beutler-Traktovenko , Marcel Franz , Judith Daniels , Julia Schellong , Kerstin Weidner , Ilona Croy","doi":"10.1016/j.psychres.2024.116345","DOIUrl":"10.1016/j.psychres.2024.116345","url":null,"abstract":"<div><div>Dissociative symptoms are a frequent complication in posttraumatic stress disorders affecting about a third of all PTSD patients. While theoretical models predict a physiological hypoarousal during posttraumatic dissociations, empirical evidence is lacking. We addressed this by studying spontaneously occurring dissociative symptoms and related heart rate changes in an ecological momentary assessment. Therefore, we continuously measured heart rate for five to ten days with mobile ECG in 47 female inpatients diagnosed with posttraumatic stress disorder and dissociative symptoms. During this observation period, patients tracked each dissociative event on a smartphone app and reported on symptom characteristics.</div><div>Patients reported a total of 164 dissociative events. Those typically lasted <30 min and involved co-occuring depersonalization and derealization of moderate to severe intensity. Tracked symptoms correlated positively with some conventional self-reports for depersonalization and derealization. Heart rate during dissociative symptoms varied greatly between and within individuals and was on average not different from baseline assessment. There was also no significant relation between dissociation intensity and heart rate change.</div><div>These results challenge the theory of reactive hypoarousal during chronic dissociation and support the view that physiological adaptation modifies in the course of posttraumatic chronification. They also highlight the individual variability of dissociative symptoms and underscore the necessity of detailed assessment for targeted therapeutic approaches.</div></div>","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"344 ","pages":"Article 116345"},"PeriodicalIF":4.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AI in substance use recovery: Innovation or risk? A call for caution 人工智能在药物使用康复中的应用：创新还是风险？请谨慎行事。

IF 4.2 2区医学

Psychiatry Research Pub Date : 2025-02-01 DOI: 10.1016/j.psychres.2024.116193

Erfan Ramadhani , Ramtia Darma Putri , Vasco Delano , M．Taheri Akhbar , Erdiansyah Erdiansyah , Muhammad Kurniawan

引用次数: 0

Maternal vitamin B12 during pregnancy and schizophrenia in offspring 孕期母体维生素 B12 与后代的精神分裂症。

IF 4.2 2区医学

Psychiatry Research Pub Date : 2025-02-01 DOI: 10.1016/j.psychres.2024.116284

Andre Sourander , Sanju Silwal , Heljä-Marja Surcel , Susanna Hinkka-Yli-Salomäki , Keely Cheslack-Postava , Subina Upadhyaya , Ian W. McKeague , Alan S. Brown

{"title":"Maternal vitamin B12 during pregnancy and schizophrenia in offspring","authors":"Andre Sourander , Sanju Silwal , Heljä-Marja Surcel , Susanna Hinkka-Yli-Salomäki , Keely Cheslack-Postava , Subina Upadhyaya , Ian W. McKeague , Alan S. Brown","doi":"10.1016/j.psychres.2024.116284","DOIUrl":"10.1016/j.psychres.2024.116284","url":null,"abstract":"<div><h3>Background</h3><div>Maternal nutritional deficiency is linked with several adverse outcomes in offspring but the link between maternal vitamin B12 levels and offspring schizophrenia remains unexplored.</div></div><div><h3>Methods</h3><div>In this nationwide population-based nested case-control design, 1145 schizophrenia cases were born between 1987-1997 and diagnosed by 2017 and each case were matched with a control. Maternal vitamin B12 levels during the first and early second trimesters of pregnancy were measured using chemiluminescence microparticle immunoassay from maternal sera. Conditional logistic regression was used to examine the association between maternal vitamin B12 levels and offspring schizophrenia.</div></div><div><h3>Results</h3><div>Low maternal vitamin B12 levels were not associated with offspring schizophrenia in unadjusted (OR 1.04, 95% CI 0.88-1.24) or adjusted analyses (aOR 1.14, 95% CI 0.95-1.37). When analyzed by quintiles, no significant association was observed between the lowest versus highest quintile of maternal vitamin B12 levels and schizophrenia in unadjusted (OR 1.01, 95% CI 0.78-1.30) or adjusted analyses (OR 0.89, 95% CI 0.68-1.17).</div></div><div><h3>Conclusion</h3><div>Maternal vitamin B12 levels in early pregnancy were not associated with offspring schizophrenia. Future studies measuring both genetic and environmental factors are required to elucidate the role of maternal vitamin B12 deficiency in schizophrenia and its potential pathways to influence schizophrenia in offspring.</div></div>","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"344 ","pages":"Article 116284"},"PeriodicalIF":4.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19′s silent scars: The urgent link between SARS-CoV-2 infection and long-term mental health consequences COVID-19 的无声伤疤：SARS-CoV-2感染与长期精神健康后果之间的紧急联系。

IF 4.2 2区医学

Psychiatry Research Pub Date : 2025-02-01 DOI: 10.1016/j.psychres.2024.116322

Yun Xie , Jiajun Wu , Shun Zhu , Ruilan Wang

引用次数: 0

The use of Experience Sampling Method in psychopharmacological studies: A systematic review 经验抽样法在精神药理学研究中的应用：系统综述。

IF 4.2 2区医学

Psychiatry Research Pub Date : 2025-02-01 DOI: 10.1016/j.psychres.2024.116327

Davy Quadackers , Fionneke Bos , Johanna Hovenkamp-Hermelink , Danielle Cath , Harriëtte Riese

{"title":"The use of Experience Sampling Method in psychopharmacological studies: A systematic review","authors":"Davy Quadackers , Fionneke Bos , Johanna Hovenkamp-Hermelink , Danielle Cath , Harriëtte Riese","doi":"10.1016/j.psychres.2024.116327","DOIUrl":"10.1016/j.psychres.2024.116327","url":null,"abstract":"<div><div>The Experience Sampling Method (ESM) is increasingly used to validate and assess treatment effects. We conducted a systematic review to update, and extend, the previous review by Bos et al. (2015), by performing literature searches in PubMed, PsycInfo, and EMBASE. Search queries included every DSM-disorder, ATC-listed psychotropic medication, and multiple search-terms for ESM. Studies included medicated psychiatric patients who filled-out ambulatory prompts ≥2/day. Templates served to distil research themes. The majority of the 79 included studies involved substance use- (<em>n</em> = 47), mood- (<em>n</em> = 17), and psychotic disorders (<em>n</em> = 11). Less studied were anxiety disorders and PTSD (<em>n</em> = 3), and ADHD (<em>n</em> = 1). We identified six research themes:1)Effects of psychopharmacological treatment on symptoms and factors influencing outcome, 2)Fluctuations of psychiatric symptoms in medicated patients, 3)Prediction of relapse, exacerbation of symptoms or medication non-compliance, 4)Added value of ESM compared to care as usual, 5)Using ESM to establish treatment response-trajectories, 6)Acceptability and feasibility of newly-devised ESM-applications. This review reveals that ESM is predominantly used in psychopharmacological studies to monitor treatment effects and establish fluctuations of momentary psychiatric symptoms. Future research might facilitate personalising psychopharmacological prescribing decisions using ESM. Currently underrepresented patient groups include elderly patients, and personality disorders. Finally, to facilitate ESM-implementation multiple context-levels should be optimised.</div></div>","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"344 ","pages":"Article 116327"},"PeriodicalIF":4.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative efficacy of multiple non-invasive brain stimulation to treat major depressive disorder in older patients: A systematic review and network meta-analysis study based on randomized controlled trials 多次无创脑刺激治疗老年患者重度抑郁症的比较疗效：基于随机对照试验的系统评价和网络荟萃分析研究

IF 4.2 2区医学

Psychiatry Research Pub Date : 2025-02-01 DOI: 10.1016/j.psychres.2024.116340

Yang Yang , Jianglin Chen , Min Yu , Cheng Xiong , Rong Zhang , Guohui Jiang

{"title":"Comparative efficacy of multiple non-invasive brain stimulation to treat major depressive disorder in older patients: A systematic review and network meta-analysis study based on randomized controlled trials","authors":"Yang Yang , Jianglin Chen , Min Yu , Cheng Xiong , Rong Zhang , Guohui Jiang","doi":"10.1016/j.psychres.2024.116340","DOIUrl":"10.1016/j.psychres.2024.116340","url":null,"abstract":"<div><h3>Background</h3><div>Major depressive disorder (MDD) is prevalent among older patients and is frequently associated with cognitive decline and a reduced quality of life. Non-invasive brain stimulation (NIBS) techniques show promise for treating MDD, but their comparative efficacy and safety older populations remain unclear. This study aimed to compare the efficacy and cognitive effects of various NIBS techniques in treating MDD in older patients.</div></div><div><h3>Methods</h3><div>We searched the PubMed, EMBASE, Cochrane Library, and Web of Science core databases from inception to March 2024. Seventeen randomized controlled trials (RCTs) were included.</div></div><div><h3>Results</h3><div>Surfaces under the cumulative ranking curve (SUCRA) values were used to rank the interventions. The SUCRA rankings for the Hamilton Depression Rating Scale (HDRS) outcomes indicated that repetitive transcranial magnetic stimulation (rTMS) (89.0 %) had the highest efficacy, followed by transcranial direct current stimulation (tDCS) (68.7 %). rTMS demonstrated significantly superior efficacy compared with bilateral electroconvulsive therapy (BL ECT) and right unilateral electroconvulsive therapy (RUL ECT). Theta burst stimulation (TBS) had the highest response rate (69.6 %), followed by rTMS (61.8 %). Based on the Mini-Mental State Examination, rTMS (86.4 %) ranked the highest, with RUL ECT showing significantly better outcomes than BL ECT.</div></div><div><h3>Conclusion</h3><div>NIBS, particularly rTMS and TBS, may offer effective treatment options for older patients with MDD. Further research with larger sample sizes and longer follow-up periods is required to validate these findings and inform clinical practice.</div></div>","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"344 ","pages":"Article 116340"},"PeriodicalIF":4.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142910407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unipolar mania over the course of a 15-year follow-up study 一项为期15年的随访研究。

IF 4.2 2区医学

Psychiatry Research Pub Date : 2025-02-01 DOI: 10.1016/j.psychres.2024.116348

Hua-Meng Shi , De-Gua Jiang

{"title":"Unipolar mania over the course of a 15-year follow-up study","authors":"Hua-Meng Shi , De-Gua Jiang","doi":"10.1016/j.psychres.2024.116348","DOIUrl":"10.1016/j.psychres.2024.116348","url":null,"abstract":"<div><h3>Objective</h3><div>A proportion of patients with bipolar disorder (BD) manifests with only Unipolar mania (UM). We conducted a follow-up study of patients diagnosed with Unipolar mania and compared them as a group if they had a mild depressive episode with those who did not.</div></div><div><h3>Method</h3><div>248 subjects were prospectively followed-up to 15 years. During the 15-year follow-up study, Pure mania was defined as patients who did not experience mild depressive episodes(203) and Mania with mild depression was defined as patients who did experience mild depressive episodes(45). Then, we compare characterization of clinical features between Pure mania (PM) and Mania with mild depression (MMD).</div></div><div><h3>Results</h3><div>Compared with the Mania with mild depression group, the Pure mania group had more psychotic symptoms, fewer suicidal behaviors, a higher proportion of morningness chronotype, better sleep quality, higher extraversion, lower neuroticism, and less harm avoidance personality traits. Substantially different lifetime comorbidity patterns were observed between the two groups.</div></div><div><h3>Conclusion</h3><div>Patients with Pure mania exhibited distinct clinical and psychosocial features compared with patients with the Mania with mild depression. Further studies are warranted to investigate the underlying mechanisms for diverse presentations in subgroups of BDs.</div></div><div><h3>Limitations</h3><div>These results apply to a relatively short outcome period, and the sample size is relatively small.</div></div>","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"344 ","pages":"Article 116348"},"PeriodicalIF":4.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142953998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Autism spectrum disorder and anorexia nervosa: Investigating the behavioural and neurocognitive overlap 自闭症谱系障碍和神经性厌食症：行为和神经认知重叠的研究。

IF 4.2 2区医学

Psychiatry Research Pub Date : 2025-02-01 DOI: 10.1016/j.psychres.2024.116285

M. Kirkovski , G. Papavasiliou , B.E. Speranza , J. Scarfo , N. Albein-Urios , J. Linardon , A. Phillipou , M. Fuller-Tyszkiewicz , P.G. Enticott

{"title":"Autism spectrum disorder and anorexia nervosa: Investigating the behavioural and neurocognitive overlap","authors":"M. Kirkovski , G. Papavasiliou , B.E. Speranza , J. Scarfo , N. Albein-Urios , J. Linardon , A. Phillipou , M. Fuller-Tyszkiewicz , P.G. Enticott","doi":"10.1016/j.psychres.2024.116285","DOIUrl":"10.1016/j.psychres.2024.116285","url":null,"abstract":"<div><div>Autism spectrum disorder (autism) and anorexia nervosa (AN) share many clinical features. Two key neurocognitive correlates of the autistic dyad, specifically, mentalising (social impairment) and set-shifting (restricted and repetitive behaviours/interests [RRBI]) were investigated in a sample of 327 adult participants with autism (<em>n</em> = 100; 50 females, 50 male), AN (<em>n</em> = 82; 54 females, 28 male), autism and AN (<em>n</em> = 45; 36 females, 9 male), and 100 (50 female, 50 male) control participants from the general population. A battery of self-report (Autism Spectrum Quotient, Eating Disorder Examination Questionnaire, Reflective Function Questionnaire, and Repetitive Behaviour Questionnaire 2 – Adult version) and performance-based (Wisconsin Card Sort Task [WCST] and Penn Emotion Recognition Test [ER-40]) measures were administered online. Clinical participants reported greater mentalising difficulty, more repetitive behaviour, and displayed worse mentalising ability compared to controls, with no difference between the clinical groups. Eating disorder psychopathology predicted error (total and perseverative) rates on the WCST, while lower levels of autistic traits were positively associated with ER-40 accuracy. We provide evidence that clinical features of autism and AN might have specific neurocognitive relevance. Improved understanding of the mechanisms underlying the overlapping features of autism and AN can have critical implications for early detection and improved and tailored intervention.</div></div>","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"344 ","pages":"Article 116285"},"PeriodicalIF":4.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0