{"title":"AI-based Triage in Breast Cancer Screening Reduces Workload with Noninferior Cancer Detection but Higher Recall.","authors":"Rebecca Breen, Maggie Chung","doi":"10.1148/rycan.269018","DOIUrl":"10.1148/rycan.269018","url":null,"abstract":"","PeriodicalId":20786,"journal":{"name":"Radiology. Imaging cancer","volume":"8 4","pages":"e269018"},"PeriodicalIF":7.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13435063/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148631386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intratumoral Therapy with or without Pulsed Electric Field Ablation for Hepatocellular Carcinoma: A Proof-of-Concept Study.","authors":"Noreen S Siddiqi","doi":"10.1148/rycan.269017","DOIUrl":"10.1148/rycan.269017","url":null,"abstract":"","PeriodicalId":20786,"journal":{"name":"Radiology. Imaging cancer","volume":"8 4","pages":"e269017"},"PeriodicalIF":7.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13435061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148631458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luigi Nardone, Elif Öcal, Lukas Salvermoser, Matthias Philipp Fabritius, Daniel Puhr-Westerheide, Matthias Stechele, Stefanie Corradini, Jens Ricke, Moritz Wildgruber, Marianna Alunni-Fabbroni, Max Seidensticker
{"title":"MRI Mapping in Meningioma: A Clinical Perspective on Presentation and Management.","authors":"Ramona-Alexandra Todea","doi":"10.1148/rycan.260299","DOIUrl":"10.1148/rycan.260299","url":null,"abstract":"","PeriodicalId":20786,"journal":{"name":"Radiology. Imaging cancer","volume":"8 4","pages":"e260299"},"PeriodicalIF":7.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13435125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148163786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nu N Le, Wen Li, Lisa J Wilmes, Natsuko Onishi, Jessica E Gibbs, Deep Hathi, Pouya Metanat, Bonnie N Joe, John Kornak, Dariya Malyarenko, Thomas L Chenevert, Patrick Bolan, Savannah C Partridge, Nola M Hylton
{"title":"Automated Apparent Diffusion Coefficient Measurement of Breast Tumors in Diffusion-weighted MRI for Early Neoadjuvant Chemotherapy Response Assessment.","authors":"Nu N Le, Wen Li, Lisa J Wilmes, Natsuko Onishi, Jessica E Gibbs, Deep Hathi, Pouya Metanat, Bonnie N Joe, John Kornak, Dariya Malyarenko, Thomas L Chenevert, Patrick Bolan, Savannah C Partridge, Nola M Hylton","doi":"10.1148/rycan.250606","DOIUrl":"10.1148/rycan.250606","url":null,"abstract":"<p><p>Purpose To develop a fully automated method for measuring apparent diffusion coefficient (ADC) for breast tumors in diffusion-weighted MRI that is objective, repeatable, and reproducible for assessing early response to neoadjuvant chemotherapy. Materials and Methods This study was a retrospective analysis of American College of Radiology Imaging Network 6698 trial data (August 2012-January 2015). Regions of interest (ROIs) were automatically derived by transferring the tumor ROI from dynamic contrast-enhanced MRI to diffusion-weighted MRI via image registration, and the ΔADC were calculated from baseline to early treatment. The ΔADC performance was assessed for predicting a pathologic complete response (pCR) using receiver operating characteristic curve analysis. The analysis was performed in all participants and in subgroups defined by tumor human epidermal growth factor receptor 2 (HER2) status. The reproducibility of automated tumor ADC measurements was assessed in a test-retest subcohort. Results The analysis cohort included 226 participants with breast cancer (mean age, 48 years ± 10 [SD]). Automated ADC measurements were reproducible in the test-retest subcohort (<i>n</i> = 71; estimated agreement index, 0.82 [95% CI: 0.77, 0.85]). The ΔADC from the automated ROI predicted pCR, with an area under the receiver operating characteristic curve (AUC) of 0.61 (95% CI: 0.53, 0.69; <i>P</i> = .008). The AUC in the HER2-positive subcohort (0.69 [95% CI: 0.54, 0.93]) was higher than that in the HER2-negative subcohort (0.52 [95% CI: 0.41, 0.62]; <i>P</i> = .06). Conclusion The automated ADC measurement method was reproducible, and tumor ΔADC could predict pCR early. External validation will be included in future work. <b>Keywords:</b> Breast, MRI, DWI, Diffusion-weighted Imaging, Tumor Response, DCE, Dynamic Contrast-enhanced, MR Imaging, MR-Diffusion-weighted Imaging, MR-Dynamic Contrast-enhanced Clinical trial registration no. NCT01564368</p>","PeriodicalId":20786,"journal":{"name":"Radiology. Imaging cancer","volume":"8 4","pages":"e250606"},"PeriodicalIF":7.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13435071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148579760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}