Radiology. Imaging cancer最新文献

{"title":"From Precise Segmentation to Scalable Annotation: A Critical Step Toward Clinical Translation of Multisequence MRI for Predicting Microvascular Invasion in Hepatocellular Carcinoma.","authors":"Zhibin Huang, Fajin Dong","doi":"10.1148/rycan.260068","DOIUrl":"10.1148/rycan.260068","url":null,"abstract":"","PeriodicalId":20786,"journal":{"name":"Radiology. Imaging cancer","volume":"8 2","pages":"e260068"},"PeriodicalIF":5.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13036669/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147366208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retroperitoneal Fetus in Fetu.","authors":"Jun Guo, Xian-Zheng Tan","doi":"10.1148/rycan.250723","DOIUrl":"10.1148/rycan.250723","url":null,"abstract":"","PeriodicalId":20786,"journal":{"name":"Radiology. Imaging cancer","volume":"8 2","pages":"e250723"},"PeriodicalIF":5.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13036686/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147309530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum for: Evaluation, Optimization, and Validation of a Multiparametric CT Algorithm for Solid Renal Masses: CT-Score Version 2.0.","authors":"Satheesh Krishna, Mayooran Kandasamy, Rajesh Bhayana, Bipin Nanda, Kanika Diwan, Ameen Kamona, Sabah Sairafi, Susan Prendeville, Yangqing Deng, Antonio Finelli, Matthew S Davenport, Nicola Schieda","doi":"10.1148/rycan.269005","DOIUrl":"10.1148/rycan.269005","url":null,"abstract":"","PeriodicalId":20786,"journal":{"name":"Radiology. Imaging cancer","volume":"8 2","pages":"e269005"},"PeriodicalIF":5.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13036673/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147487177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective Head-to-Head Comparison of ¹⁸F-FDG and ⁶⁸Ga-FAPI PET/CT in De Novo and Recurrent Epstein-Barr Virus-associated Nasopharyngeal Carcinoma.","authors":"Bingxin Gu, Shuyi Lin, Liyan Bai, Chaosu Hu, Xiaomin Ou, Zhongyi Yang, Shaoli Song","doi":"10.1148/rycan.250437","DOIUrl":"10.1148/rycan.250437","url":null,"abstract":"<p><p>Purpose To compare gallium 68 (⁶⁸Ga) fibroblast activation protein inhibitor (FAPI) PET/CT with plasma Epstein-Barr virus (EBV)-DNA load measurement, contrast-enhanced MRI/CT, and fluorine 18 (¹⁸F) fluorodeoxyglucose (FDG) PET/CT for nasopharyngeal carcinoma (NPC) initial assessment and recurrence surveillance. Materials and Methods Participants with NPC who underwent both ¹⁸F-FDG and ⁶⁸Ga-FAPI PET/CT examinations within 1 week for initial assessment (treatment-naive cohort) and recurrence surveillance (posttreatment cohort) were enrolled in this prospective study conducted between July 2020 and November 2023 (Chinese Clinical Trial Registry identifier no. ChiCTR2100054163). The data of plasma EBV DNA load and contrast-enhanced MRI/CT were analyzed. Diagnostic performance was compared using the McNemar test. The relationships between plasma EBV DNA and the two tracers were assessed by using simple linear regression analysis. Results Sixty-five participants (median age, 50 years [IQR, 41.50-61 years]; 50 male) were included, with 31 in the treatment-naive cohort and 34 in the posttreatment cohort. In participant-level analysis, ⁶⁸Ga-FAPI PET/CT demonstrated the highest accuracy rate in identifying the participants with de novo (100% [31 of 31] vs 84% [26 of 31], 77% [24 of 31], and 84% [26 of 31], <i>P</i> = .06, .02, and .06, respectively) and recurrent (94% [32 of 34] vs 53% [18 of 34], 68% [23 of 34], and 85% [29 of 34], <i>P</i> = .001, .02, and .25, respectively) NPC, compared with plasma EBV DNA, contrast-enhanced MRI/CT, and ¹⁸F-FDG PET/CT. Furthermore, compared with contrast-enhanced MRI/CT and ¹⁸F-FDG PET/CT, ⁶⁸Ga-FAPI PET/CT led to upstaging in five of 31 (16%) and downstaging in four of 31 (13%) treatment-naive participants. Lesion uptake at ⁶⁸Ga-FAPI PET/CT did not correlate with plasma EBV DNA load (<i>P</i> > .05). Conclusion ⁶⁸Ga-FAPI PET/CT outperformed plasma EBV DNA level, contrast-enhanced MRI/CT, and ¹⁸F-FDG PET/CT in initial assessment and recurrence surveillance of NPC. <b>Keywords:</b> Head/Neck, PET/CT, Nasopharyngeal Carcinoma, Epstein-Barr Virus, Fibroblast Activation Protein Inhibitor, FDG Chinese Clinical Trial Registry identifier no. ChiCTR2100054163 <i>Supplemental material is available for this article.</i> © RSNA, 2026.</p>","PeriodicalId":20786,"journal":{"name":"Radiology. Imaging cancer","volume":"8 2","pages":"e250437"},"PeriodicalIF":5.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13036655/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146258979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lymph Node Metastases Prediction in Cervical Cancer Using Time-Dependent Diffusion MRI and Macromolecular Proton Fraction Imaging.","authors":"Nan Meng, Jiayin Pan, Wei Wei, Jing Sun, Bo Dai, Yan Wang, Xuan Yu, Wanyue Li, Baiyan Jiang, Jian Hou, Weitian Chen, Meiyun Wang","doi":"10.1148/rycan.250452","DOIUrl":"10.1148/rycan.250452","url":null,"abstract":"<p><p>Purpose To examine whether time-dependent diffusion MRI (T_d-dMRI) and macromolecular proton fraction (MPF) mapping-derived quantitative metrics can effectively distinguish between cervical cancer with and without lymph node metastasis (LNM) before treatment. Materials and Methods In this prospective study of adults with clinically suspected cervical cancer who underwent T_d-dMRI, MPF mapping, and pulsed gradient spin-echo diffusion-weighted imaging (DWI_PGSE) examinations between October 2023 and June 2025, authors calculated T_d-dMRI-derived parameters (cellularity, diameter, intracellular volume fraction [V_in], and extracellular diffusivity [D_ex]), MPF, and DWI_PGSE-derived parameter (pulsed gradient spin-echo apparent diffusion coefficient [ADC_PGSE]). Through Ridge regression analysis, the authors identified independent predictors of LNM and developed a composite diagnostic tool using logistic regression analysis. To evaluate tool performance, the area under the receiver operating characteristic curve was determined. Results Among 98 female individuals with cervical cancer (mean age, 56.69 years ± 11.63 [SD]), participants who were LNM positive exhibited higher cellularity, V_in, and MPF but lower diameter, D_ex, and ADC_PGSE than their counterparts who were LNM negative (<i>P</i> < .001 to <i>P</i> = .007). Cellularity, maximum tumor diameter, and MPF were independent predictors of LNM status, with their combination yielding the best diagnostic performance (area under the receiver operating characteristic curve, 0.95; 95% CI: 0.89, 0.98). The performance of this combination surpassed that of individual imaging modality, including DWI_PGSE (ADC_PGSE), and MPF, as well as any individual parameter, including cellularity, V_in, diameter, and D_ex. Conclusion T_d-dMRI and MPF mapping were effective for predicting LNM in cervical cancer, with the combination of cellularity, maximum tumor diameter, and MPF showing the best diagnostic performance. <b>Keywords:</b> Time-Dependent Diffusion MRI, Macromolecular Proton Fraction, Cervical Cancer, Lymph Node Metastases © RSNA, 2026.</p>","PeriodicalId":20786,"journal":{"name":"Radiology. Imaging cancer","volume":"8 2","pages":"e250452"},"PeriodicalIF":5.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13036659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147309559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Software-specific A0 Thresholds for Minimum Ablative Margins after Liver Tumor Thermal Ablation: A Large-Scale Simulation Study.","authors":"Fiona Mankertz","doi":"10.1148/rycan.269006","DOIUrl":"10.1148/rycan.269006","url":null,"abstract":"","PeriodicalId":20786,"journal":{"name":"Radiology. Imaging cancer","volume":"8 2","pages":"e269006"},"PeriodicalIF":5.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13036652/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147487121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI and Breast Cancer Screening at a Crossroads: Insights from the MASAI Trial.","authors":"Andrea Cozzi","doi":"10.1148/rycan.269007","DOIUrl":"10.1148/rycan.269007","url":null,"abstract":"","PeriodicalId":20786,"journal":{"name":"Radiology. Imaging cancer","volume":"8 2","pages":"e269007"},"PeriodicalIF":5.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13036691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147532302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spectral CT Electron Density Mapping for Lung Biopsy Targeting.","authors":"Yingying Hu, Hongliang Sun","doi":"10.1148/rycan.250778","DOIUrl":"10.1148/rycan.250778","url":null,"abstract":"","PeriodicalId":20786,"journal":{"name":"Radiology. Imaging cancer","volume":"8 2","pages":"e250778"},"PeriodicalIF":5.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13036672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147532333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular Imaging of Hepatocellular Carcinoma with Third-Generation US Contrast Agents: Toward Clinical Translation.","authors":"Jinshun Xu","doi":"10.1148/rycan.260025","DOIUrl":"10.1148/rycan.260025","url":null,"abstract":"","PeriodicalId":20786,"journal":{"name":"Radiology. Imaging cancer","volume":"8 2","pages":"e260025"},"PeriodicalIF":5.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13036671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147366188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intrahepatic Splenosis Mimicking Hepatocellular Carcinoma.","authors":"Hui-Hui Zhang, Xian-Zheng Tan","doi":"10.1148/rycan.250444","DOIUrl":"10.1148/rycan.250444","url":null,"abstract":"","PeriodicalId":20786,"journal":{"name":"Radiology. Imaging cancer","volume":"8 2","pages":"e250444"},"PeriodicalIF":5.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13036676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147366257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}