Przeglad epidemiologiczny最新文献

{"title":"Implementation of the preventive vaccination program in the time of the COVID-19 pandemic - single center study.","authors":"Marek Wojczyk,&nbsp;Marcelina Potocka","doi":"10.32394/pe.77.08","DOIUrl":"https://doi.org/10.32394/pe.77.08","url":null,"abstract":"<p><strong>Introduction: </strong>In addition to many diagnostic and therapeutic procedures, the COVID-19 pandemic also limited prophylaxis, including the implementation of the vaccination program among children.</p><p><strong>Objective: </strong>The aim of the study was to assess the implementation of the vaccination program in the area covered by the care of patients of a selected Primary Health Care clinic in the city of Krakow in the field of selected vaccinations during the COVID-19 pandemic.</p><p><strong>Material and methods: </strong>A retrospective study based on secondary data was conducted in a selected clinic (Kraków, Poland) that cares for 1,982 children aged 0-19 years. An analysis of the vaccination coverage in selected groups of children in 2019, 2020 and 2021 was carried out based on annual reports (MZ-54). Vaccination coverage against: diphtheria, tetanus, whooping cough, measles, mumps, rubella, influenza and pneumococcal infection was analyzed. The collected data were analyzed using descriptive statistics, Chi2 test and Fisher's exact test.</p><p><strong>Results: </strong>In the general vaccination status of two-year-olds, no significant differences were observed in the period 2019-2021 (p=0.156). The percentage of fully vaccinated increased from 77.6% in 2019, to 81.5% in 2020 and to 85.2% in 2021. However, a high rate of vaccination refusals was observed in 2021 (4.1%) in this group. The percentage of 2-year-olds vaccinated against pneumococci (PCV) and 3-year-olds against diphtheria, tetanus, pertussis (DTP), and measles, mumps, rubella (MMR) in the years 2019-2021 was increasing. For DTP and MMR, this increase was significant (p<0.05). In the group of older children, in 2020 the percentage of 7- and 15-year-olds vaccinated decreased compared to 2019 and 2021, but the difference was insignificant (p>0.05). A significant difference in vaccination coverage was observed in the group of 19-year-olds, in which in 2020 the percentage of vaccinated was 58% (in 2019 - 74.6%, in 2021 - 81%). The largest number of children under the age of 5 were vaccinated against influenza in 2021, but it was only less than 2% of this group.</p><p><strong>Conclusions: </strong>Sanitary restrictions introduced during the COVID-19 pandemic did not significantly affect the vaccination status of children in selected age groups against the analyzed vaccine-preventable diseases. The exception is the group of 19-year-olds, whose vaccination coverage in 2020 was much lower than in 2019 and 2021. In addition, an increase in refusals of vaccination was observed, reaching 4.1% in 2021 in the group of the youngest patients.</p>","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":"77 1","pages":"74-83"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9590891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Asymptomatic carrier of Babesia spp. among blood donors - epidemiological situation in Poland.","authors":"Adam Kaczmarek,&nbsp;Aleksandra Matras,&nbsp;Agata Stasiak,&nbsp;Tomasz Chmielewski,&nbsp;Marta Stanek,&nbsp;Rusłan Sałamatin","doi":"10.32394/pe.77.14","DOIUrl":"10.32394/pe.77.14","url":null,"abstract":"<p><strong>Introduction: </strong>Babesiosis is caused by one of several Babesia species. In Europe, B. divergens predominates in humans, while in North America it is B. microti. Babesia spp. infection in donors with a disease-free course of infection can be a major problem in blood recipients. A recipient with impaired immune system functions is at risk of full-blown development of the disease. In Poland and in most countries of the world, blood donors are not routinely tested for Babesia spp. infection. In our previous study, we detected Babesia venatorum DNA in blood donors, which was the reason for expanding the study to include more test subjects.</p><p><strong>Objective: </strong>The aim of this study was an attempt at estimating the prevalence of asymptomatic infection with Babesia spp. among blood donors from the Regional Centres for Blood Donation and Blood Treatment in Warsaw and Wrocław.</p><p><strong>Materials and methods: </strong>The material for the study was whole blood from regular blood donors from two Regional Centre for Blood Donation and Blood Treatment in Warsaw and Wrocław. Whole blood samples from 1,067 blood donors collected in June-July 2022 were analyzed. Blood collected directly from the donor during the blood donation procedure. All persons qualified by a doctor as a donor were selected for the study, regardless of age and sex. All subjects were informed in detail about the purpose of the study and gave their written consent. Isolation was made by using the Chelex 100 chelating resin, followed by the studying of the genetic material using the qPCR reaction. The results were analysed based on the amplification curve.</p><p><strong>Results: </strong>The protozoan Babesia spp. was not detected in the blood samples.</p><p><strong>Conclusions: </strong>The risk of blood-borne babesiosis is extremely low in Poland.</p>","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":"77 2","pages":"146-152"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49692055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Etiological factors of bloodstream infections in oncological patients, who was hospitalized at the National Institute of Maria Skłodowska-Curie - National Research Institute in Warsaw in 2020-2022.","authors":"Katarzyna Darmofalska, Anna Skowrońska, Agnieszka Woźniak, Maria Pawelec, Joanna Skrzeczyńska, Elżbieta Ochman, Agnieszka Magdziak","doi":"10.32394/pe.77.26","DOIUrl":"10.32394/pe.77.26","url":null,"abstract":"<p><strong>Aim of the study: </strong>The purpose of the study was the microbiological analysis of bloodstream infections in patients hospitalized at the National Institute of Oncology, Maria Skłodowska-Curie - National Research Institute in the period from 01/01/2020 to 31/10/2022.</p><p><strong>Material and methods: </strong>In the period from 01/01/2020 to 31/10/2022, 18,420 blood cultures obtained from patients hospitalized at the NIO-PIB were analysed in the Department of Clinical Microbiology (total for the presence of bacteria and fungi). Culture for the presence of bacteria was carried out in the BactAlert automatic system by bioMerieux, and for fungi in the Bactec FX automatic system by Becton Dickinson.</p><p><strong>Results: </strong>1,184 strains of bacteria and 32 strains of fungi considered to be the etiological factor of the infection were cultured from clinical samples. Gram-positive bacteria accounted for 61.57%, while Gram-negative bacteria accounted for 32.26% of all isolated bacterial strains. The most frequently cultured strains were Escherichia coli - 13.77% (including 22.1% of ESBL strains), Klebsiella penumoniae - 4.6% (44.4% of ESBL strains, 1.85% of NDM strains), Enterobacter cloacae - 2 .7% (including 40.6% of multi-resistant strains: ESBL (15.6%) or with AmpC derepression (25%), among the non-fermenting bacilli, Pseudomonas aeruginosa was the most frequently cultured - 4.18% (including 3.8% MBL) and Acinetobacter baumannii - 0.8% (including CRAB strains 50%, MBL 10%). Anaerobic microorganisms were responsible for 3.46% of blood infection cases. Yeast- like fungi were a factor in 2.7% of all fungemia cases. From blood samples taken Staphylococci were more frequently isolated directly from a vein or through a central venous catheter than aerobic Gram-negative bacilli (44.7% and 25.3% and 55.6% and 12.5%, respectively). The opposite situation occurred in the case of samples taken simultaneously directly from vein and through a central venous catheter, in which a higher share of aerobic Gram-negative bacilli (46.6%) than staphylococci (32.8%) in causing blood infections was observed.</p><p><strong>Conclusions: </strong>Gram-positive bacteria are the major contributors to bloodstream infections in cancer patients. There is a growing tendency to develop BSI caused by multi-resistant strains.</p>","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":"77 3","pages":"279-290"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139703288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of implementing Peplau's theory of interpersonal communication on the quality of life of patients with acquired immunodeficiency syndrome.","authors":"Bahareh Sarami,&nbsp;Sam Myrfendereski,&nbsp;Shahriar Salehi Tali,&nbsp;Ali Hasanpour-Dehkordi,&nbsp;Hadi Reisi","doi":"10.32394/pe.77.10","DOIUrl":"https://doi.org/10.32394/pe.77.10","url":null,"abstract":"<p><strong>Background and objectives: </strong>Patients with AIDS face many problems, including problems related to treatment, social and family exclusion, high treatment costs, and drug complications, which affect the quality of life of these patients and change it. The aim was to determine the effect of the application of Peplau's theory of interpersonal communication on the quality of life of patients with acquired immunodeficiency syndrome.</p><p><strong>Material and method: </strong>This quasi-experimental study was performed on 50 AIDS patients referred to Shahrekord Behavioral Diseases Counseling Center. Simple random sampling was performed and then the sample was assigned to two groups experimental and control. The theory of therapeutic communication of Peplau on patients in the experimental group was performed individually and immediately after the intervention and three months later the quality of life questionnaire was completed in both groups. In this research, the data collection tool includes a demographic information questionnaire and a WHOQOL-BREF. The WHOQOLBREF questionnaire measures the four domains of physical health, mental health, social relationships, and environmental health with 24 questions. The chi-square or Fisher's exact test, independent T-test and analysis of variance with repeated measurements were used to compare the quality of life of patients.</p><p><strong>Results: </strong>Data analysis showed no statistically significant difference in the mean score of quality of life between the experimental and control groups before the implementation of Peplau's interpersonal communication theory (p=0.927). But after the intervention, there was a statistically significant difference in the mean score of quality of life between the two groups (p < 0.001).</p><p><strong>Conclusion: </strong>Findings of the study show the positive effects of using Peplau's therapeutic communication model on quality of life. Therefore, this method is recommended as an effective and cost-effective care model for all patients referred to the Shahrekord Behavioral Diseases Counseling Center.</p>","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":"77 1","pages":"101-107"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9590900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case report: severe course of encephalitis of unknown origin.","authors":"Jakub Okrzeja,&nbsp;Piotr Czupryna,&nbsp;Bożena Kubas,&nbsp;Justyna Adamczuk,&nbsp;Joanna Zajkowska,&nbsp;Adam Garkowski","doi":"10.32394/pe.77.16","DOIUrl":"10.32394/pe.77.16","url":null,"abstract":"<p><p>The exact cause of encephalitis is still unclear in many cases, although the common etiological factors of this process are viruses such as herpes simplex virus and rabies virus, and also bacteria, fungi, parasites, several medicines and autoimmune diseases. Herein, we report a case of a 56-year-old man with a history of amnestic syndrome, impaired consciousness, somnolence throughout the day, headache, dizziness and hypertension, who was admitted to hospital with suspected neurological disease, and imaging features that were consistent with encephalitis of unknown etiology. Methods which were used to examine patient: cerebrospinal fluid testing, PCR examinations for viruses, testing of antibodies against surface antigens, magnetic resonance imaging of the head, psychiatric consultation, oncology consultation. The objective of this study is to demonstrate a case about an uncommon neurologic condition, which every clinician might meet in clinical practice. In this type of cases, the use of steroids such as dexamethasone and methylprednisolone might lead to a full recovery.</p>","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":"77 2","pages":"163-171"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41238093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the usefulness of COVID-19 antigen tests in primary health care on the example of Kashubian Medical Centre in Sierakowice.","authors":"Piotr Tomczyk,&nbsp;Dominika Tomczyk,&nbsp;Stanisław Czerwonka","doi":"10.32394/pe.77.18","DOIUrl":"10.32394/pe.77.18","url":null,"abstract":"<p><strong>Introduction: </strong>The SARS-CoV-2 pandemic is described as a global health crisis. The most typical symptoms of infection prompt most patients to visit a primary care clinic (PCC). From December 2020, COVID-19 can be diagnosed in European Union countries on the basis of a positive antigen test result. These tests are widely used at the primary care level.</p><p><strong>Material and methods: </strong>The analysis covered the period from 01.09.2021 to 28.02.2022. Statistical analysis was performed on the results of a study of 1,849 patients who underwent antigen testing in primary care clinics at the Kashubian Medical Centre (KCM) in Sierakowice and data published by the Ministry of Health on the results of tests performed from the whole country, Pomeranian Voivodeship and Kartuzy County.</p><p><strong>Results: </strong>Statistical analysis showed that the results of studies conducted in KCM in Sierakowice (antigen-only tests) were consistent with the results of studies conducted in Kartuzy County, Pomeranian Voivodeship and nationwide (molecular PCR - Polymerase Chain Reaction and antigen tests).</p><p><strong>Conclusions: </strong>Rapid antigen tests are a useful diagnostic tool in the fight against the SARS-CoV-2 pandemic because of their easy availability and simplicity of performance, and their widespread dissemination, especially in primary care settings, could contribute to multibillion-dollar savings in the health care system.</p>","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":"77 2","pages":"185-198"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41238095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seroprevalance of anti-SARS-CoV-2 antibodies in the IgG class in hospitalized children in the north-eastern part of Poland in 2021.","authors":"Katarzyna Leszko,&nbsp;Artur Sulik,&nbsp;Beata Żelazowska-Rutkowska","doi":"10.32394/pe.77.15","DOIUrl":"10.32394/pe.77.15","url":null,"abstract":"<p><strong>Introduction: </strong>In children, SARS-CoV-2 infection may manifest with symptoms of fever, cough, muscle pain, diarrhea or waste smell and taste. However, in most cases it is mild or asymptomatic. Determination of the level of anti-SARS CoV-2 IgG antibodies in children enables to assess retrospectively the incidence of the SARS-CoV-2 infection among children.</p><p><strong>Aim of the study: </strong>The aim of the research was to analyze the results of anti-SARS-CoV-2 antibodies in the IgG class contained in children hospitalized in north-eastern Poland in 2021.</p><p><strong>Material and methods: </strong>The material for the study was venous blood collected once from children hospitalized in Children's University Hospital in Białystok in 2021. The results obtained from 615 children aged from 1 month to 11 years were analyzed. Determination of the level of antibodies was performed using the automated SARS-COV-2 IgG II test on the VIDAS® analyzer.</p><p><strong>Results: </strong>The analysis of the results of the anti-SARS-CoV-2 IgG value showed that half of children (52%, n=319) had contact with SARS-CoV-2 virus of which approximately 15% (n=47) had documented infection with this virus. There was no difference in the frequency of infections among boys and girls, antibodies were detected in 51% and 53%, respectively. The highest percentage of positive results was observed in children aged 7 to 10 years, 62% (91/147). The least children with a positive result were in the group below 1 year of age, 24% (4/17). High values of the antibody index (>15.00) were most often found among younger children, aged 1-2 years.</p><p><strong>Conclusions: </strong>The presented results showed that infection with the SARS-CoV-2 virus does not depend on the sex of children but the value of anti-SARS-CoV-2 IgG antibodies decreased with the age of the child.</p>","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":"77 2","pages":"153-162"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41238097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of lifestyle and nutritional status between women with and without metabolic syndrome.","authors":"Lucyna Pachocka, Małgorzata Mękus","doi":"10.32394/pe.77.31","DOIUrl":"10.32394/pe.77.31","url":null,"abstract":"<p><strong>Introduction: </strong>Amidst the growing epidemic of obesity and diabetes, metabolic syndrome (MetS) is one of the greatest health problems. Lifestyle factors and bad habits are responsible for the emergence and development of MetS.</p><p><strong>Objective: </strong>The aim of the study was to compare and check whether women with MetS adhered to a healthy diet and had a healthier lifestyle than women without MetS, and to compare the impact of women's lifestyles on their nutritional status.</p><p><strong>Material and methods: </strong>The study included 167 women aged 20-78. As per guidelines, all tests required fasting. Comparisons of individual quantitative variables between groups were made using the Student's t-test for independent variables or the Mann-Whitney U-test. The relationship between quantitative variables was verified with the Spearman correlation coefficient. All statistical tests were based on a significance level of p<0.05.</p><p><strong>Results: </strong>Women with MetS were more likely to have bad habits such as smoking, adding sugar to beverages and adding salt to food on the plate, while alcohol consumption was more common in women without MetS, but there was a statistically significant positive correlation between alcohol consumption and HDL-cholesterol levels in both groups. Women with MetS showed statistically significantly higher body weight, BMI, waist and hip circumferences (p<0.001), a statistically significant positive relationship between adding sugar to beverages and triglyceride levels (r=0.2699, p=0.015). In women without MetS, there was a statistically significant negative correlation between HDL-cholesterol levels and cigarette smoking (r= 0.2709, p=0.014). Women with MetS had statistically significantly higher mean systolic and diastolic blood pressure and mean serum levels of total cholesterol (p<0.001), LDL-cholesterol (p=0.007), triglycerides (p<0.001) and glucose (p<0.001) than women without MetS.</p><p><strong>Conclusions: </strong>Nutritional errors were shown in both groups, including deficiencies in calcium, folates, iron, vitamin D and excessive sodium and phosphorus intake. Therefore, it is important to prevent the onset of MetS components and to educate and assist professionals in setting realistic goals individually adapted to each patient.</p>","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":"77 3","pages":"344-358"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139703286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulmonary embolism in patients in acute COVID-19, long-COVID and post-COVID syndrome.","authors":"Piotr Tomczyk,&nbsp;Dominika Tomczyk","doi":"10.32394/pe.77.17","DOIUrl":"10.32394/pe.77.17","url":null,"abstract":"<p><p>COVID-19 is a disease caused by the SARS-CoV-2 virus, which, after entering a living organism, uses the ACE-2 protein as a receptor and several other proteins as cofactors of infection. Disease symptomatology is extensive, involving mostly predominant respiratory symptoms, as well as those of the nervous, gastrointestinal, circulatory and other systems. Incidence of COVID-19 also results in markedly different laboratory findings on the hemostatic system with the predominant feature of increased D-dimer levels. In the pathogenesis of thromboembolic complications in COVID-19, all elements of Virchow's triad are involved: endothelial damage, coagulation disorders and blood flow disorders. Coagulopathy increases with the severity of the clinical course of COVID-19. One of the causes of mortality associated with COVID-19 is pulmonary embolism. SARS-CoV-2 infection increases the risk of thromboembolic complications not only in the acute period of the disease. Also in the period of about a month after recovery, there is an increased risk of venous thrombosis and consequently, life-threatening pulmonary embolism. The classic biomarker of pulmonary embolism in the general population is D-dimers. Among imaging studies, the gold standard for diagnosing this disease is computed tomography of the pulmonary arteries (CTPA). Other useful diagnostic tests are ventilation-perfusion lung scintigraphy (VQ Scans) or echocardiography. Currently reviewed guidelines and recommendations recommend extens ive thromboprophylaxis in COVID-19 patients in both acute and chronic phases of the disease. Keywords: COVID-19, pulmonary embolism, laboratory and imaging diagnostics, thromboprophylaxis.</p>","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":"77 2","pages":"172-184"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41238096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-drug resistant strains as etiological agents of urinary tract infections in patients after solid organ transplantation.","authors":"Piotr Wilkowski,&nbsp;Ewa Hryniewiecka,&nbsp;Kornelia Jasińska,&nbsp;Michał Ciszek","doi":"10.32394/pe.77.12","DOIUrl":"10.32394/pe.77.12","url":null,"abstract":"<p><strong>Introduction: </strong>Urinary tract infections (UTIs) caused by multi-drug resistant strains are a serious and growing problem in organ transplant (TX) recipients.</p><p><strong>Aim of the study: </strong>The aim of the study was to assess the prevalence and risk factors of UTIs caused by multi-drug resistant strains in hospitalized patients after kidney or liver transplantation in a large transplant center.</p><p><strong>Material and methods: </strong>392 cases of UTIs in patients after kidney or liver TX hospitalized in 2014, 2015 and 2016 were analyzed. Among the assessed cases of UTIs, 66.07% occurred in women, 33.93% - in men, 80.1% - in kidney TX recipients and 19.9% - in liver TX recipients. The median age of the patients was 57.51 years and the median time since TX was 41.44 months.</p><p><strong>Results: </strong>Most episodes of UTIs were observed during the first year after TX - 121 (30.78%) of cases. A total of 506 pathogens were cultured: 345 Gram-negative bacteria (68.182%), 146 Gram-positive bacteria (28.854%) and 15 fungi (2.964%). More than one pathogen was found in 25.51% of urine cultures. Among bacteria (n=491), a resistance mechanism was detected in 166 (33.81%) pathogens (133 Gram-negative and 33 Gram-positive). The most common etiological agents were: E. coli ESBL- (23.72%), K. pneumoniae ESBL+ (17.19%), E. faecalis (11.27%) and E. faecium (7.71%). Diabetes was present in 129 (35.46%) of patients, and the number of UTI cases was similar in the group with and without diabetes.</p><p><strong>Conclusions: </strong>Compared to the general population, in hospitalized patients after kidney or liver transplantation UTIs occur more often in men and are more often caused by Gram-positive bacteria. In 33.81% of cases UTIs are caused by multi-drug resistant strains, predominantly Gram-negative bacteria.</p>","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":"77 2","pages":"127-135"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41210710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}