Przeglad epidemiologiczny最新文献

{"title":"Foodborne infections and intoxications in Poland in the years 2018-2020.","authors":"Piotr Polański, M. Sadkowska-Todys, Ewelina Księżak, Zuzanna Nowacka","doi":"10.32394/pe.76.57","DOIUrl":"https://doi.org/10.32394/pe.76.57","url":null,"abstract":"AIM\u0000The purpose of this study is to assess the epidemiological situation of foodborne infections and intoxications in Poland in the years 2018-2020.\u0000\u0000\u0000MATERIALS AND METHODS\u0000The evaluation was based on the analysis of information sent to Department of Epidemiology NIPH NIH - NRI through ROE (pol. Rejestr Ognisk Epidemicznych) - an electronic system created for uploading, transfer and analysis of data acquired during the outbreak investigations. Additional sources for the analysis were NIPH NIH - NRI annual bulletins (Czarkowski MP et al. \"Infectious diseases and poisonings in Poland\", 2014-2020. Warsaw, NIPH NIH and GIS).\u0000\u0000\u0000RESULTS\u0000In the years 2018-2020 a total number of 2,108 foodborne outbreaks were reported in which 52,175 persons were exposed and 17,023 got sick (in 2016 n=916, in 2019 n=918, in 2020 n=274). In 2020 over 3 fold decrease in the number of outbreaks comparing to 2019 and over 4 fold decrease in the number of cases in those outbreaks was observed. Among outbreaks which took place in 3 most frequent settings (private household, food facility and hospital) the steepest decrease was in 12th week of 2020 (ISO 2020-W12). The most frequent etiological agent of outbreaks in the years 2018-2020 was Salmonella sp. (38.3% of outbreaks in 2018, 32.7% in 2019 and 47.8% in 2020) and specifically serotype Enteritidis (38.3%, 27% and 39.4% accordingly). The most frequent setting of outbreaks was private household (59.7% outbreaks in 2018, 66% in 2019 and 62% in 2020), followed by hospital (17.4%, 18.3% i 19.7% accordingly). Up until 2019 an increasing trend in the number of small outbreaks (up to 4 cases) caused by Salmonella sp. was observed (in 2018 - 605 and in 2019 - 612 were reported).\u0000\u0000\u0000CONCLUSIONS\u0000Decrease in the number of outbreaks in selected settings from 12th ISO week of 2020 might have been due to introduction of restrictions during COVID-19 pandemic and enhancement of personal hygiene practices. An increase in identified and registered small outbreaks caused by Salmonella sp. comparing to the median of the number of those outbreaks from 2014-2016 could partly be a result of routine surveillance enhancement after introducing System for Registry of Epidemiological Interviews (pol. SRWE).","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":"76 4 1","pages":"626-640"},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45062107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19-associated acute pancreatitis: a systematic review of case reports.","authors":"Zahra Rahimian,&nbsp;Afrooz Feili,&nbsp;Rezvan Ghaderpanah,&nbsp;Seyedhassan Sadrian,&nbsp;Seyed Ali Hosseini,&nbsp;Maryam Ranjbar,&nbsp;Maryam Feili,&nbsp;Kamran Bagheri Lankarani","doi":"10.32394/pe.77.07","DOIUrl":"https://doi.org/10.32394/pe.77.07","url":null,"abstract":"<p><strong>Introduction: </strong>Coronavirus disease 2019 (COVID-19) mainly involves the respiratory system but can also affect the digestive system and cause several gastrointestinal manifestations. Acute pancreatitis has been reported as one of the rare presentations of COVID-19. This study aimed to systematically review case reports on COVID-19-associated acute pancreatitis.</p><p><strong>Methods: </strong>Publications were retrieved through a comprehensive search in four databases on October 1, 2021. Eligible ones that demonstrated the potential association of acute pancreatitis and COVID-19 were included for data extraction.</p><p><strong>Results: </strong>After screening 855 citations, 82 articles containing 95 cases were included, and their data were extracted. The most common presentation was abdominal pain (88/95, 92.6%), followed by nausea/vomiting (61/95, 64.2%). Mortality was reported in 10.5% of cases. The initial presentation was acute pancreatitis, COVID-19, and concomitant in 32.6% (31/95), 48.4% (46/95), and 18.9% (18/95) of cases, respectively. Among the included cases, acute pancreatitis severity was associated with ICU admission, COVID-19 severity, and the outcome. Also, the initial presentation was associated with COVID-19 severity (P values ˂0.05).</p><p><strong>Conclusions: </strong>Current evidence indicates that acute pancreatitis can present before, after, or concomitant with COVID-19. Appropriate investigations should be performed in cases with suspicious clinical presentations. Longitudinal studies should address whether or not, there is a causative relationship between COVID-19 and acute pancreatitis.</p>","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":"77 1","pages":"66-73"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9590897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacterial complications in patients with coronavirus infection, new diagnostic and therapeutic possibilities.","authors":"Marceli Łukaszewski,&nbsp;Kamil Nelke","doi":"10.32394/pe.77.06","DOIUrl":"https://doi.org/10.32394/pe.77.06","url":null,"abstract":"<p><p>We present the case of a young patient who developed pneumonia during the COVID-19 outbreak. The course of the disease with involvement of interstitial lung tissue atypical for bacterial infections, the picture of infection markers could indicate SARS-CoV-2. The patient was tested by PCR method on admission with negative results. Due to the atypical follow-up of the disease, suggesting a severe course of SARS, PCR testing of the material collected by BAL was performed BIOFIRE® FILMARRAY® Pneumonia plus Panel (bioMérieux). Legionella pneumophilla and coronavirus genetic materials were found. We conclude that in the described case there was a bacterial co-infection, paved by virus infection. The similar radiological picture of the two cases of pneumonia, as well as the similar infectious response in the blood, specific for atypical infections, may pose a problem in the differential diagnosis. The study was able to confirm the bacterial etiology of pneumonia and introduce targeted treatment. The patient was discharged from the hospital. We believe that in any case of pneumonia of non-bacterial etiology, extending the diagnosis with a PCR pulmonary panel allows early and effective treatment of patients. In the treatment of patients with pulmonary interstitial lesions in the course of virus infections, one should always keep in mind the possibility of atypical co-infections.</p>","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":"77 1","pages":"59-65"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9589404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychosocial functioning of women suffering from stress and mixed form of urinary incontinence depending on the severity of the symptoms.","authors":"Agnieszka Chrostek,&nbsp;Joanna Witkoś,&nbsp;Magdalena Hartman-Petrycka,&nbsp;Agata Lebiedowska","doi":"10.32394/pe.77.09","DOIUrl":"https://doi.org/10.32394/pe.77.09","url":null,"abstract":"<p><strong>Introduction: </strong>Urinary incontinence is a troublesome symptom that negatively affects many aspects of life among woman suffering from this disease. It disturbs social, professional and intimate relations, and thus contributes to a negative self-image, loss of self-confidence, withdrawal of a woman from social and family life, and consequently promotes negative state of mind and depression.</p><p><strong>Aim: </strong>The aim of the study was to analyse the influence of urinary incontinence on the psychosocial functioning of women suffering from this disease.</p><p><strong>Material and methods: </strong>The study included a group of 202 women aged 40.1 ± 13.9 years. A proprietary questionnaire was used, aimed at all women who had an episode of urinary incontinence at any time in their life.</p><p><strong>Results: </strong>The impact and perception of the urinary incontinence symptoms depended on its form and severity. Comparing stress urinary incontinence with the mixed form, a greater severity of symptoms in women with the mixed form were observed, respectively 13.6% vs. 53.9%. Taking into account the aspects of life affected by urinary incontinence, it was found that the greatest impact UI had on the social (52.5%), then on the professional (28.7%), and the least impact on the family aspect of life (21.8%).</p><p><strong>Conclusions: </strong>Research has shown that urinary incontinence has the greatest impact on the social aspect of the surveyed women's life. The reported impact largely depended on the form and severity of urinary incontinence. In over 40% of women, symptoms related to urinary incontinence caused a deterioration of wellbeing and body acceptance. The mixed form was by far the most problematic and had the greatest impact on the daily functioning of women compared to, for example, the stress form.</p>","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":"77 1","pages":"84-100"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9582601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacterial meningitis in adults - principles of diagnosis and antibiotic treatment.","authors":"Aleksander M Garlicki,&nbsp;Mirosław Jawień,&nbsp;Sławomir A Pancewicz,&nbsp;Anna Moniuszko-Malinowska","doi":"10.32394/pe.77.01","DOIUrl":"https://doi.org/10.32394/pe.77.01","url":null,"abstract":"<p><p>The emergence of antibiotic-resistant bacterial strains in recent years has necessitated the development of new strategies for empiric antimicrobial therapy for bacterial meningitis. Bacterial meningitis is associated with significant morbidity and mortality despite the availability of effective antimicrobial therapy. The management approach to patients with suspected or proven bacterial meningitis includes initiation of appropriate antimicrobial and adjunctive therapies and decides on the patients survival.</p>","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":"77 1","pages":"3-22"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9592164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the prevalence of risk factors for Toxoplasma Gondii infection among pregnant women in rural and urban areas in Poland.","authors":"Carlo Bieńkowski, Maciej Stępień, Martyna Cholewik, Małgorzata Aniszewska, Maria Pokorska-Śpiewak","doi":"10.32394/pe.77.27","DOIUrl":"10.32394/pe.77.27","url":null,"abstract":"<p><strong>Introduction: </strong>Toxoplasma gondii is a protozoan parasite. While this infection typically exhibits no symptoms in humans, it poses a potential threat to the developing fetus in pregnant women. Several risk factors contribute to toxoplasmosis infection. Adherence to hygiene protocols and avoiding the consumption of raw meat, unwashed vegetables, and fruits may mitigate the risk of this disease.</p><p><strong>Objective: </strong>This study aimed to compare the prevalence of toxoplasmosis risk factors among pregnant women suspected of toxoplasmosis living in rural areas with those residing in urban areas.</p><p><strong>Materials and methods: </strong>A retrospective observational study was conducted by analyzing data from the medical records of pregnant women suspected of toxoplasmosis. These women were consulted at the Provincial Infectious Diseases Hospital between September 2019 and March 2020. The analysis encompassed patients' demographic data and information concerning toxoplasmosis risk factors. A total of 273 women's data were included in the analysis. Diagnosis relied on serological verification using the VIDAS® analyzer (bioMérieux, Lyon, France).</p><p><strong>Results: </strong>Women residing in rural areas were less likely to report a good socio-economic status (p=0.0064), and toxoplasmosis infection was less frequently ruled out (p=0.0023). In comparison to women living in urban areas, pregnant women from rural regions were more likely to have confirmed primary toxoplasmosis (p=0.0164). Additionally, they were more prone to working in gardens without gloves (p<0.0001), consuming unwashed vegetables (p=0.0025), eating raw meat during pregnancy (p=0.0008), and cats caregiving during pregnancy (p=0.0002). This exposure included both care for domestic cats before and during pregnancy (p=0.0069) and interactions with wild cats (p<0.0001).</p><p><strong>Conclusions: </strong>Pregnant women living in rural areas exhibited significantly higher exposure to toxoplasmosis risk factors. They also displayed a higher incidence of primary infections during pregnancy and a lower rate of excluded infections.</p>","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":"77 3","pages":"291-301"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139703287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychosocial contexts of the HIV epidemic in Poland.","authors":"Agnieszka Walendzik-Ostrowska, Rafał Majka, Joanna Dec-Pietrowska, Maria Brodzikowska, Magdalena Ankiersztejn-Bartczak","doi":"10.32394/pe.77.28","DOIUrl":"10.32394/pe.77.28","url":null,"abstract":"<p><p>The article is an attempt to collect and describe non-medical aspects of the HIV epidemic in Poland in 2023, aspects that often elude epidemiology and treatment specialists. However, they are crucial to public health and, as such, require a presence in the discourse on the broader issue of the HIV epidemic in our country.</p>","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":"77 3","pages":"302-316"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139703290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seroprevalence of Helicobacter pylori infections in children and adults in Poland in the years 2020-2023.","authors":"Waldemar Rastawicki, Klaudia Wiechetek-Płaza","doi":"10.32394/pe.77.29","DOIUrl":"10.32394/pe.77.29","url":null,"abstract":"<p><strong>Introduction: </strong>Helicobacter pylori is a common cause of gastrointestinal infections in people around the world. Various microbiological methods are used in the laboratory diagnosis of infections, including determining the presence of specific antibodies in the serum. Serological tests can also be used in epidemiological studies aimed at determining the incidence of H. pylori infections.</p><p><strong>Objective: </strong>The aim of the study was to obtain insight into the incidence of antibodies to H. pylori in subjects of different ages living in Poland in the years 2020-2023.</p><p><strong>Material and methods: </strong>The research used serum samples obtained between January 2020 and September 2023 from 600 subjects living in Poland. The Anti-Helicobacter pylori ELISA IgG enzyme immunoassay from Euroimmun was used to test the level of IgG antibodies to H. pylori antigens. Additionally, selected serum samples were tested for the presence of antibodies to the most important protein virulence factors of H. pylori by Western Blot.</p><p><strong>Results: </strong>IgG antibodies to H. pylori, at a diagnostically significant level, were detected in 28.3% of the examined persons. Antibodies to H. pylori were least frequently detected in children under 10 years of age (12.1%) and teenagers (13.2%). In adults aged 20 to 50, these antibodies were more common (23.9% to 29.5%). Statistically, H. pylori antibodies were most often detected in subjects over 50 years of age (52.3%). There were no statistically significant differences in the frequency of antibodies to H. pylori depending on the gender of the examined persons. In most serum samples tested by Western Blot, the presence of antibodies to the CagA protein was detected (66.7%).</p><p><strong>Conclusions: </strong>The conducted research and analysis of literature data showed a similar percentage of serum samples with a diagnostically significant level of antibodies to H. pylori in people living in Poland as in people living in other European countries. The epidemiology of infections is also very similar, characterized by low morbidity in children and adolescents and an increase in the incidence of infections with the age of the examined persons. Importantly, compared to research conducted in our country several years ago, the percentage of positive results is much lower, which may be due to the improvement of social and living conditions and hygiene habits.</p>","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":"77 3","pages":"317-326"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139703292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meningitis and encephalitis in Poland in 2021.","authors":"Karolina Mrozowska-Nyckowska, Jakub Zbrzeźniak, Iwona Paradowska-Stankiewicz","doi":"10.32394/pe.77.35","DOIUrl":"10.32394/pe.77.35","url":null,"abstract":"<p><strong>Introduction: </strong>Meningitis meningitis and/or encephalitis regardless of etiology are subject to monitoring in Poland as part of routine epidemiological surveillance. In this paper, meningitis and/or encephalitis in 2021 caused by Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae and tick-borne encephalitis virus are discussed in detail. In Poland, immunoprophylaxis in the form of mandatory or recommended vaccinations is used to prevent diseases caused by the aforementioned etiological agents.</p><p><strong>Aim of the study: </strong>The aim of this study was to assess the epidemiological incidence of meningoencephalitis and encephalitis in Poland, in 2021 including analysis of the impact of the COVID-19 pandemic.</p><p><strong>Material and methods: </strong>To analyse the epidemiological situation of neuroinfections in Poland, we used data sent to NIPH NIH - NRI by Voivodeship Sanitary and Epidemiological Stations and published in the annual bulletin: \"Infectious diseases and poisonings in Poland in 2021\" and \"Protective vaccination in Poland in 2021\" as well as individual epidemiological interviews recorded in the EpiBase system.</p><p><strong>Results: </strong>In 2021, a total of 973 cases of meningitis and/or encephalitis were registered in Poland. This is a 16.1% increase in the number of cases compared to 2020, but still a 57% decrease in the number of cases compared to 2019 when 2,249 cases were recorded. For infections of bacterial etiology, including cases of neuroborreliosis, the number of cases increased by 38.3% (from 376 to 520, incidence from 0.96 to 1.76 per 100,000). Compared to 2020 and 2019, the incidence of meningitis and/or encephalitis of N. meningitidis decreased by 10.7% (from 0.13 to 0.15) and 47.4% (from 0.25 to 0.13), respectively, and for H. influenzae by 75% (from 0.01 to 0.03) and 70% (from 0.01 to 0.03). For S. pneumoniae, we can speak of an increase in incidence against 2020 of 57.1% (121 vs 77 cases, incidence 0.32 vs 0.20) and a decrease against 2019. (121 vs 190, incidence 0.32 vs 0.47). Infections of viral etiology accounted for 47% of all registered cases. There was a slight decrease in their number, by 2% (from 462 to 453 cases). In addition, there was an increase in cases of tick-borne encephalitis, from 158 in 2020 to 210 in 2021 (an increase of 32.9%), and a decrease in cases from 265 in 2019 (a decrease of 20.8%).</p><p><strong>Summary and conclusions: </strong>2021 showed an overall upward trend in the number of recorded cases of bacterial meningitis and/or encephalitis, and a slight decrease in the number of viral meningitis and/or encephalitis cases compared to 2020. Still, the observed number of meningitis and/or encephalitis cases in 2021, both bacterial and viral incidences, remains below the levels observed in the pre-pandemic COVID-19 period (2019). As a result of the SARS-CoV-2 outbreak, the introduction of measures to limit the transmission of the SARS-CoV-","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":"77 3","pages":"387-402"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139707687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sir Frederick Grant Banting - the discoverer of insulin. On the 100th anniversary on the Nobel Prize.","authors":"Konrad Barszczewski,&nbsp;Radosław Karaś,&nbsp;Martyna Biadasiewicz,&nbsp;Halina Kulik,&nbsp;Tomasz Lepich","doi":"10.32394/pe.77.11","DOIUrl":"https://doi.org/10.32394/pe.77.11","url":null,"abstract":"<p><p>Over the past thousands of years, diabetes has deprived people all over the world of their lives. Until 1922, mankind remained powerless. However, change came, with Frederick Banting (1891-1941), the discoverer of insulin. This breakthrough discovery was made not by a great scientist, but by a hard-working and persistent doctor. Perhaps Banting's conscientiousness and integrity stemmed from where he grew up? A small farm in the provinces certainly influenced his further development. A development that was not obvious, because as a child little Freddie had learning difficulties. Determination led him to medicine. It must not have been without surprise to Professor MacLeod (1876-1935) when, in his office at the University of Ontario, he heard from the 30-year-old doctor that he had an idea on how to save lives from an incurable disease. The opportunity Banting was given, he used effectively. Together with the help of his student Charles Best (1899-1978), he isolated insulin. The dissemination of insulin in Poland was very quickly taken up by Kazimierz Funk (1884-1967), the discoverer of thiamine and creator of the term 'vitamin'. As head of the Department of Biochemistry at the National Institute of Hygiene (PZH), he began producing insulin from bovine pancreases in 1924. He carried out this initiative using his private funds, equipping the laboratory with the appropriate equipment. Banting's remarkable feat was rewarded in 1923. Nobel Prize, which he shared with MacLeod. The fact that the actual co-discoverer of insulin, Charles Best, was not included in the award outraged Banting to such an extent that he decided not to accept the prize. After much persuasion, he changed his mind, but shared the financial reward with his faithful assistant. The discoverer's determination and behaviour in the face of success provides an invaluable lesson for today's doctors and scientists. By following the principles Banting espoused, we can honour his memory.</p>","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":"77 1","pages":"108-118"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9590899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}