Psychiatric Quarterly最新文献

{"title":"Are S100B and VILIP-1 Involved in a Common Mechanism of Neuroinflammation in Major Depressive Disorder?","authors":"Nagihan Ayaz Naycı, Aybeniz Civan Kahve, Hasan Kaya, Andaç Uzdoğan, Yağmur Darben Azarsız, Süreyya Barun, Erol Göka","doi":"10.1007/s11126-024-10102-w","DOIUrl":"10.1007/s11126-024-10102-w","url":null,"abstract":"<p><p>This study aimed to evaluate the role of neuroinflammation in neuronal and glial cells in the pathophysiology of Major Depressive Disorder (MDD) through different biomarkers.S100-B and VILIP-1 levels of patients diagnosed with MDD were evaluated before and after antidepressant treatment. A total of 65 patients diagnosed with MDD and 69 healthy controls were included. Serum levels of S100B and VILIP-1 were measured at the time of diagnosis and after eight weeks antidepressant treatment and compared with healthy controls. Hamilton Depression Rating Scale (HDRS) and the Clinical Global Impression Scale (CGI) were applied to assess the severity of depression. In our study, although serum S100B levels were higher in patients before treatment compared to healthy controls, this difference was not statistically significant. Regarding VILIP-1 levels, there was no statistically significant difference between patients and healthy controls. A positive and statistically significant correlation was found between S100B and VILIP-1 levels in MDD group before the treatment. At the eighth week of treatment, a statistically significant positive correlation was also found between S100B and VILIP-1 levels. Our research is the first study to evaluate MDD through two separate biomarkers specific to glial and neuronal cells.The fact that S100B and VILIP-1 levels showed significant correlations in patients diagnosed with MDD both before and after treatment suggests that they may play a shared role in the pathophysiology of the disorder. The correlation between S100B and VILIP-1 may serve as a guide in understanding the pathophysiology of the disorder and in identifying new drug development targets.</p>","PeriodicalId":20658,"journal":{"name":"Psychiatric Quarterly","volume":" ","pages":"19-37"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Network Analysis of Depression and Cognitive Impairments in Fibromyalgia: A Secondary Analysis Study.","authors":"Dariush Tahmasebi Aghbelaghi, Mahbobeh Jalali, Natalie Tayim, Roghayeh Kiyani","doi":"10.1007/s11126-024-10106-6","DOIUrl":"10.1007/s11126-024-10106-6","url":null,"abstract":"<p><strong>Introduction: </strong>Fibromyalgia is a chronic condition often accompanied by cognitive impairments, such as difficulties with sustained attention, and emotional disturbances, particularly depression and anxiety. Understanding how these emotional and cognitive factors interact is crucial to improving treatment for fibromyalgia patients. This study aimed to investigate the network structure of these interactions, focusing on the relationship between depression, anxiety, and cognitive performance.</p><p><strong>Method: </strong>A total of one hundred ten participants diagnosed with fibromyalgia completed self-reported assessments of depression and anxiety, alongside cognitive performance tests. Key measures included Continuous Performance Tasks (CPT) for impulsivity and sustained attention, the Stroop Interference Index (StI), Stroop Color Naming (StC), and Stroop Word Reading (StW). Network analysis was conducted to estimate the relationships between emotional and cognitive variables and assess their centrality within the network.</p><p><strong>Results: </strong>Errors in CPT emerged as the most significant indicators of the relationship between depression and cognitive performance, with high centrality values observed for the Stroop tasks (StI, StC, and StW). Additionally, Trait Anxiety (A_T) and Beck Depression Inventory (BDI) measures showed high centrality, underscoring the critical role of emotional states in the network of cognitive and emotional variables. The centrality values for cognitive flexibility, processing speed, and inhibitory control were found to be 0.85, 0.78, and 0.72, respectively.</p><p><strong>Conclusion: </strong>This study highlights the strong association between depression symptoms and deficits in cognitive domains, emphasizing the need for integrated care approaches that address both cognitive and emotional health. Multidisciplinary treatment programs, including cognitive rehabilitation and psychological support, could improve patient outcomes by targeting the most influential variables in the cognitive-emotional network.</p>","PeriodicalId":20658,"journal":{"name":"Psychiatric Quarterly","volume":" ","pages":"39-57"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142716973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conscientiousness, Public Service Motivation, Resilience, and Work Engagement among Volunteers in Lebanon.","authors":"Hussein Mreydem, Issa Kamal Eddine, Moussa Hojeij, Han Sung Lee, Pascale Salameh, Seockhoon Chung","doi":"10.1007/s11126-025-10115-z","DOIUrl":"10.1007/s11126-025-10115-z","url":null,"abstract":"<p><p>We conducted a descriptive-analytical cross-sectional study using an online survey to explore the personality traits of volunteers in Lebanon and examine their relationship with work engagement, psychological status, resilience, and public service motivation. A total of 270 volunteers were recruited through social media platforms. The survey included general questions about volunteering, Utrecht Work Engagement Scale-9 items (UWES-9), the Big Five Personality Inventory-10 (BFPI-10), the Patient Health Questionnaire-9 (PHQ-9), the Generalized Anxiety Disorder-7 (GAD-7), the Public Service Motivation (PSM), and the Connor-Davidson Resilience Scale-2 (CD-RISC2). The results revealed that agreeableness and conscientiousness levels were significantly lower among volunteers with low work engagement compared to those with high work engagement. Work engagement was positively correlated with agreeableness and conscientiousness and negatively correlated with neuroticism. Logistic regression showed that being single with a low level of conscientiousness, public service motivation, and resilience predicted low work engagement. Mediation analysis showed that conscientiousness, public service motivation, and resilience directly influenced work engagement, and depression mediated the relationship of conscientiousness and resilience with work engagement. This study highlights the importance of personality traits, mental health, and motivation in understanding work engagement among volunteers, which can help in designing strategies to enhance volunteers' experiences, well-being, and productivity.</p>","PeriodicalId":20658,"journal":{"name":"Psychiatric Quarterly","volume":" ","pages":"227-240"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143067406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychiatrists' Attitude Towards Smoking Cessation Support (PATSS): Exploring Psychometric Properties of the Measurement Tool.","authors":"Parul Parul, Bindu Joseph, Sunil Datta, Muhammad Aziz Rahman","doi":"10.1007/s11126-025-10116-y","DOIUrl":"10.1007/s11126-025-10116-y","url":null,"abstract":"<p><p>The attitude of psychiatrists plays a crucial role in screening and supporting smoking cessation, especially with people with serious mental illness (SMI). The development of an attitude scale can improve the success of quitting among people with SMI. This study aimed to develop and test the psychometric properties of psychiatrists' attitudes toward smoking cessation support (PATSS). Based on the literature review, the attitude scale, which comprised 15 items, was developed and tested with 289 psychiatrists. The tool's psychometric properties were tested by examining item performance, content and construct validity (by exploratory factor analysis (EFA), confirmatory factor analysis (CFA), and reliability. The content validity was demonstrated by content validity ratio (CVR) (0.80) and item content validity index (ICVI) (0.88). Both EFA and CFA identified four factors: Priority and Time Commitment, Recovery Impact and Training, Social Support and Patient Factors, and Coping Mechanisms and Rights. A Cronbach alpha of (0.81) demonstrated high internal consistency. PATSS was found to be a valid and reliable tool to assess the attitude of psychiatrists towards smoking cessation support provided to people with SMI.</p>","PeriodicalId":20658,"journal":{"name":"Psychiatric Quarterly","volume":" ","pages":"213-226"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11929625/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143067471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Network Analysis of Core Symptoms of Internalizing and Externalizing Symptoms Among Children with Dyslexia in Saudi Arabia.","authors":"Norah Alkhateeb","doi":"10.1007/s11126-024-10105-7","DOIUrl":"10.1007/s11126-024-10105-7","url":null,"abstract":"<p><p>Researches indicate that children with dyslexia are more likely to experience psychiatric symptoms throughout life compared to peers in the general population. Improving the classification of psychiatric symptoms in this population can be a valuable goal for strengthing therapeutic models. The current study aimed to evaluate the dynamic associations between internalizing and externalizing symptoms in children with dyslexia using network analysis. This cross-sectional study was conducted in Saudi Arabia from April to July 2024, involving 183 children aged 8-11 diagnosed with dyslexia, recruited through convenience sampling from local schools and clinics. The Child Behavior Checklist (CBCL) was utilized to assess a range of psychopathological symptoms, focusing on six clusters: affective problems, anxiety problems, somatic symptoms, ADHD symptoms, oppositional defiant problems, and conduct problems. Notably, \"cries a lot\" emerged as a central symptom in the affective network, while \"dependent\" was identified as the most pivotal symptom in the anxiety network. Centrality measures-betweenness, closeness, and strength-were employed to quantify the significance of each symptom. The findings suggest that these central symptoms may contribute to the development and persistence of psychiatric comorbidities in children with dyslexia. Interventions targeting these core symptoms could enhance psychological outcomes for this population. Overall, this study lays the groundwork for future research into tailored intervention strategies to address unique psychiatric comorbidities associated with dyslexia.</p>","PeriodicalId":20658,"journal":{"name":"Psychiatric Quarterly","volume":" ","pages":"59-74"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142732092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Network Analysis of Psychological Empowerment, Need for Cognition, and Academic Self-Efficacy among Graduate Students.","authors":"Abdulaziz Mohammed Alismail, Mazen Saleh Alqurashi, Mazen Omar Almulla","doi":"10.1007/s11126-025-10117-x","DOIUrl":"10.1007/s11126-025-10117-x","url":null,"abstract":"<p><p>The present study employed network analysis to explore the interrelationships between academic self-efficacy, psychological empowerment, and the need for knowledge at the symptom level among graduate students. Three hundred fifty-three graduate students from King Faisal University, Hofuf, Saudi Arabia (63.5% male, 72.2% in the 25-35 age range) completed the Psychological Empowerment Scale, Need for Cognition Scale (NCS), and Academic Self-Efficacy Scale as self-report measures. Different R-Studio programming software packages, such as \"graph,\" \"network tools,\" and \"botnet,\" were used to analyze the current study's data. The most central node on the network analysis was Self.2 (history of success/failure), with the greatest betweenness (2.18), closeness (1.84), and strength (1.86). This node showed that it was essential for connecting other variables, despite having an expected negative effect (-0.37). Then there was also Psy.4 (impact), which showed a high centrality of betweenness 1.13 and closeness 1.29. Indeed, positive edges for Self.2 (previous successes/failures) and MB (Need for Cognition) (edge weight 0.37) clearly showed that good past experiences increased cognitive activity. A Bridge Betweenness of 10 was the most significant bridge node (Self.4 (university behavior) in the bridge analysis), linking network elements. Bootstrapped confidence intervals proved that these connections remained stable, ensuring the network was robust over resamples. Enhancing graduate students' self-efficacy and psychological empowerment, particularly through positive past experiences, could improve their academic performance and cognitive engagement. Future research should explore the implications of these findings for designing interventions to foster academic success.</p>","PeriodicalId":20658,"journal":{"name":"Psychiatric Quarterly","volume":" ","pages":"183-200"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143041154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Antidepressant Prescriptions for Community-Dwelling Adults Diagnosed with Depressive Disorder in the UK: A Systematic Review.","authors":"Lea Francia, Roberto Mediavilla, Lok Yin Choi, José Luis Ayuso-Mateos, Riccardo De Giorgi","doi":"10.1007/s11126-024-10093-8","DOIUrl":"10.1007/s11126-024-10093-8","url":null,"abstract":"<p><p>The UK National Institute for Health and Care Excellence (NICE) guidance for the treatment of depression is widely followed and has international influence. According to these guidelines, antidepressant medications are recommended for moderate to severe depression. Nonetheless, antidepressants are increasingly prescribed, including for cases of subthreshold and mild depression. This may indicate that a proportion of depressed patients uses pharmacological interventions with unclear evidence-base, though other factors such as physical and mental health comorbidities need to be accounted for. This study aims to investigate the prevalence and trends of antidepressant prescriptions among community-dwelling adults diagnosed with depression according to NICE recommendations. We conducted a systematic review of PsycInfo, PubMed/MEDLINE, and Scopus databases. Observational studies reporting on the prevalence of antidepressant treatments in UK adults diagnosed with depression were sought. Fifteen studies were included. The prevalence of antidepressants for depression treatment ranged from 30.8 to 95% and mainly concerned selective serotonin reuptake inhibitors (SSRIs) among classes of antidepressant drugs. Little information about depression severity as well as comorbid conditions was reported. High prevalence rates of antidepressant drug use highlight the widespread adoption of pharmacological interventions, while also raising concerns about compliance with NICE guidelines. Careful assessment of depressive illness severity and comorbidities is needed to ensure the delivery of adequate care to people with depression. Systematic Review Registration Number (PROSPERO) CRD42023448152.</p>","PeriodicalId":20658,"journal":{"name":"Psychiatric Quarterly","volume":" ","pages":"731-746"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142352659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Bergen-Yale Sexual Addiction Scale (BYSAS): Longitudinal Measurement Invariance Across a Two-Year Interval.","authors":"Rapson Gomez, Taylor Brown, Vasileios Stavropoulos","doi":"10.1007/s11126-024-10087-6","DOIUrl":"10.1007/s11126-024-10087-6","url":null,"abstract":"<p><p>The Bergen-Yale Sexual Addiction Scale (BYSAS; [1]) is arguably the most popular questionnaire at present for assessing sex addiction. Employing Confirmatory Factor Analysis (CFA) and treating item scores as ordered categorical, we applied Weighted Least Square Mean and Variance Adjusted Chi-Square (WLSMV) extraction to investigate the longitudinal measurement and structural invariance of ratings on the BYSAS among 276 adults (mean = 31.86 years; SD = 9.94 years; 71% male) over a two-year period, with ratings at three yearly intervals. Overall, there was support for configural invariance, full loading, full threshold, the full unique factor invariance; and all structural (latent variances and covariances) components. Additionally, there was no difference in latent mean scores across the three-time points. The psychometric and practical implications of the findings are discussed.</p>","PeriodicalId":20658,"journal":{"name":"Psychiatric Quarterly","volume":" ","pages":"561-577"},"PeriodicalIF":2.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11568058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142111329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Multiple Mediator Model of Depression, Dysfunctional Beliefs about Sleep, and Sleep Effort in the Relationship between Psychological Inflexibility and Insomnia in Shift Working Nurses.","authors":"Myung Hee Ahn, Sooyeon Suh, Seockhoon Chung","doi":"10.1007/s11126-024-10097-4","DOIUrl":"10.1007/s11126-024-10097-4","url":null,"abstract":"<p><p>The aims of this study were to explore the influence of shift working nursing professionals' psychological inflexibility on their level of insomnia. Additionally, we investigated the mediation effect of depression and sleep-related cognitions on this association. An online survey was conducted among 202 nursing professionals at Asan Medical Center from July to August, 2023. Participants responded to questionnaires including the Insomnia Severity Index (ISI), Acceptance and Action Questionnaire-II (AAQ-II), Dysfunctional Beliefs and Attitudes about Sleep - 16 (DBAS-16), Glasgow Sleep Effort Scale (GSES), Patient Health Questionnaire-9 items (PHQ-9), and the Discrepancy between desired time in bed and desired total sleep time index (DBST index). Pearson's correlation and linear regression were performed to explore the factors predicting ISI scores. Mediation analysis was implemented. Linear regression revealed that insomnia severity was predicted by DBAS-16 (β = 0.15, p = 0.008), GSES (β = 0.48, p < 0.001), and PHQ-9 (β = 0.26, p < 0.001). Mediation analysis showed that the relationship between the psychological inflexibility of shift-working nursing professionals' and insomnia severity was fully mediated by depression, dysfunctional beliefs about sleep, and sleep effort. Psychological inflexibility does not directly influence insomnia severity, but depression, dysfunctional beliefs about sleep, and sleep effort fully mediate the relationship.</p>","PeriodicalId":20658,"journal":{"name":"Psychiatric Quarterly","volume":" ","pages":"657-667"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142473150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mediating Effect of Firefighters' Resilience and Public Service Motivation Regarding the Influence of Depression on Their Work Engagement During COVID-19.","authors":"Han-Sung Lee, Soomin Jang, Yong-Wook Shin, Jeong-Hyun Kim, Seockhoon Chung","doi":"10.1007/s11126-024-10094-7","DOIUrl":"10.1007/s11126-024-10094-7","url":null,"abstract":"<p><p>In this study, we aimed to investigate the influence of resilience or public service motivation (PSM) on firefighters' work engagement during the coronavirus disease (COVID-19) pandemic. We conducted an online survey with 304 firefighters assigned to Gyeonggi-do between October 27 and 28, 2022, and collected their demographic information; work-related data; mood, anxiety and insomnia symptoms; and work-related attitudes. The leading causes of firefighters' stress were physical and mental health decline due to heavy workloads (46.4%), verbal abuse and assault from civilians (33.9%), conflict with coworkers (18.4%), and death of colleagues (13.2%). The results of the logistic regression analysis revealed that high levels of resilience (OR = 1.28, p < 0.001), service motivation (OR = 1.17, p < 0.001), and non-exposure to death (OR = 0.33, p = 0.005) led to high work engagement. Mediation analysis showed that resilience and PSM mediated the influence of depression on work engagement. The work engagement of firefighters is influenced by resilience, PSM, and exposure to death.</p>","PeriodicalId":20658,"journal":{"name":"Psychiatric Quarterly","volume":" ","pages":"669-680"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142473151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}