Journal of Alzheimer’s & Neurodegenerative Diseases最新文献

Case-Control Study Comparing the Relationship between Pain, Neurobehavioral Functioning and a History of Playing Professional Contact Sports 比较疼痛、神经行为功能和职业接触运动史之间关系的病例-对照研究

Journal of Alzheimer’s & Neurodegenerative Diseases Pub Date : 2021-12-31 DOI: 10.24966/and-9608/100058

Barry S Willer

{"title":"Case-Control Study Comparing the Relationship between Pain, Neurobehavioral Functioning and a History of Playing Professional Contact Sports","authors":"Barry S Willer","doi":"10.24966/and-9608/100058","DOIUrl":"https://doi.org/10.24966/and-9608/100058","url":null,"abstract":"Objective: Chronic pain is known to affect neurocognitive function- ing; retired professional athletes are at high risk of having chronic musculoskeletal pain. However, this relationship has not been in-vestigated in retired professional contact sport athletes who are sus- pected to have early neurocognitive decline due to repetitive head injuries during their careers. Participants: Twenty-one retired National Football League and National Hockey League players (Contact Sport, CS) and 21 age-matched non-contact sport athletic controls (Non-contact Sport, NS). Design: Case-control Main measures: Behavior Regulatory Index (BRI) and Metacogni- tive Index (MI) from Behavioral Rating Inventory of Executive Func-tion-Adult, anxiety from Beck Anxiety Index, depression from Beck Depression Inventory-II, and Pain Intensity and Interference from Patient Reported Outcome Measure Information System-43. Results: CS group reported significantly more pain intensity and interference (p<0.001) than NS. On exploratory binary logistic re-gressions, body mass index (p=0.039), pain interference (p=0.014), and anxiety (p=0.010) were significant predictors of BRI. Pain interference (p=0.002) was the sole significant predictor of MI. A history of playing contact sports was significant for neither. Conclusion: Our results suggest there may be important causes of early neurocognitive decline in this population other than just a history of playing contact sports.","PeriodicalId":205994,"journal":{"name":"Journal of Alzheimer’s & Neurodegenerative Diseases","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122094247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Parkinsonism Variant of Alzheimer’s Disease 阿尔茨海默病的帕金森变体

Journal of Alzheimer’s & Neurodegenerative Diseases Pub Date : 2021-12-31 DOI: 10.24966/and-9608/100057

N. Kasahata

引用次数: 0

Longitudinal Assessment of tau Phosphorylation in the Brainstem of P301L tau-transgenic pR5 Mice P301L tau转基因pR5小鼠脑干中tau磷酸化的纵向评估

Journal of Alzheimer’s & Neurodegenerative Diseases Pub Date : 2021-10-30 DOI: 10.24966/and-9608/100051

S. Huggenberger

引用次数: 0

The Use of a Musical Mnemonic Strategy to Support Verbal Memory Recall in People with Alzheimer’s Disease: A Review 使用音乐记忆策略支持阿尔茨海默病患者的言语记忆回忆:综述

Journal of Alzheimer’s & Neurodegenerative Diseases Pub Date : 2021-10-30 DOI: 10.24966/and-9608/100050

F. Costa

引用次数: 0

Quantum Effects Challenge Navier-Stokes Equation 量子效应挑战Navier-Stokes方程

Journal of Alzheimer’s & Neurodegenerative Diseases Pub Date : 2021-10-30 DOI: 10.24966/and-9608/100053

Shantilal Gangadas Goradia

引用次数: 0

The Role of Peripheral Cells in Neurocognitive Disorders Detection 外周细胞在神经认知障碍检测中的作用

Journal of Alzheimer’s & Neurodegenerative Diseases Pub Date : 2021-10-30 DOI: 10.24966/and-9608/100052

A. Mandas

引用次数: 0

Supranuclear Opthalmoplegia, Neck Dorsiflexion, and Midbrain Tegmentum Atrophy Associated with Brainstem Pathology of Alzheimer’s disease 核上眼麻痹、颈背屈和中脑被盖萎缩与阿尔茨海默病的脑干病理相关

Journal of Alzheimer’s & Neurodegenerative Diseases Pub Date : 2021-10-30 DOI: 10.24966/and-9608/100054

N. Kasahata

引用次数: 0

NLRP3 Inflammasome and Alzheimer's Disease NLRP3炎性体与阿尔茨海默病

Journal of Alzheimer’s & Neurodegenerative Diseases Pub Date : 2020-12-30 DOI: 10.24966/and-9608/100045

Xuemei Feng

引用次数: 1

Are “Sartans” the Common Treatment for COVID-19 and Parkinson’s Disease? “沙坦”是治疗COVID-19和帕金森病的常用药物吗?

Journal of Alzheimer’s & Neurodegenerative Diseases Pub Date : 2020-12-30 DOI: 10.24966/and-9608/100048

A. Sfera

引用次数: 1

Derivation of Diagnostic Criteria for a Slight Cognitive Impairment using CKPT (Japanese Version of CWPT) 用CKPT推导轻度认知障碍诊断标准(CWPT日文版)

Journal of Alzheimer’s & Neurodegenerative Diseases Pub Date : 2020-12-30 DOI: 10.24966/and-9608/100046

T. Shimura

{"title":"Derivation of Diagnostic Criteria for a Slight Cognitive Impairment using CKPT (Japanese Version of CWPT)","authors":"T. Shimura","doi":"10.24966/and-9608/100046","DOIUrl":"https://doi.org/10.24966/and-9608/100046","url":null,"abstract":"Objective: CWPT, which is able to detect a slight cognitive impair- ment in PCSD (Preclinical Stage of Dementia) or MCI (Mild Cognitive Impairment), is attracting attention as a neuropsychological test that allows screening at the stage where we must rely on expensive testing equipment such as PET, MRI and X-CT. CWPT is a test for identifying colors and remembering episodes while reading a story containing Color Words, so it can be easily translated and used in various languages. Therefore, the purpose of this paper is to show foreign researchers how to deriver the diagnostic criteria in Japan. Methods: Diagnostic criteria were derived by analyzing large-scale data. At this time, since it is impossible to perform MMSE on all the subjects, CKPT was performed after receiving a report that I was normal. As shown in the evidence in the previous paper, the CKPT results show a normal distribution for each age, so a method to check the distribution by subjecting the subjects who disturb the normal distribution of the resulting histogram to trial and error is achieved. Results: The total number of subjects used for the diagnostic criteria was 1325, and 199 subjects were excluded. The average value ± SD, and the average value ± 1.5SD were derived as the diagnostic criteria for male and female in their 60s, 70s, and 80s. Conclusion: Using the derived diagnostic criteria, we have gained a foothold to develop various CKPT applications.","PeriodicalId":205994,"journal":{"name":"Journal of Alzheimer’s & Neurodegenerative Diseases","volume":"529 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123360779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0